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The efficacy of temperature-guided preventive care in reducing diabetic foot ulcer incidence and prolonging ulcer-free survival: a systematic review and meta-analysis of randomized controlled trials.

INTRODUCTION: Recurrence of diabetic foot ulcers (DFU) is a major clinical challenge, often leading to amputation. Temperature-guided preventive care based on skin temperature monitoring has been proposed as an early warning tool that can trigger preventive actions before overt ulceration develops. We conducted a systematic review and meta-analysis to evaluate its efficacy in preventing DFU recurrence in high-risk individuals. METHODS: We systematically searched PubMed, Embase, the Wiley Online Library, and Web of Science for randomized controlled trials comparing temperature-guided preventiv…