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Influence of combined cardio-respiratory motion on dose to different segments of the left anterior descending coronary artery during left-sided breast cancer radiotherapy.

This study aimed to analyze and quantify the influence of cardiac positional variation on the amplitude of coronary artery movement and its potential dosimetric impact during breast carcinoma radiotherapy. 121 4DCT datasets from female patients with left-sided breast cancer were collected. The left anterior descending (LAD) coronary artery and its three segments (proximal, middle, and distal) were delineated to determine its movement amplitude. Subsequently, the dosimetric impact due to the LAD motion-inclusion effect was evaluated. All three LAD segments exhibited different displacement magni…

Reduced-Cost Four-Component Relativistic Double Ionization Potential Equation-of-Motion Coupled-Cluster Approaches with 4-Hole-2-Particle Excitations and Three-Body Clusters.

The double ionization potential (DIP) equation-of-motion (EOM) coupled-cluster (CC) method with 4-hole-2-particle (4h-2p) excitations on top of the CC with singles, doubles, and triples calculation, abbreviated as DIP-EOMCCSDT(4h-2p), along with its perturbative DIP-EOMCCSD(T)(a)(4h-2p) approximation, are extended to a relativistic four-component (4c) framework. In addition, we introduce and test a new computationally practical DIP-EOMCC approach, which we call DIP-EOMCCSD(T)(ã)(4h-2p), that approximates the treatment of 4h-2p correlations within the DIP-EOMCCSD(T)(a)(4h-2p) method and reduces…

Cardiac point-of-care ultrasound detection of regional wall motion abnormalities optimizes clinical assessment in patients with acute myocardial infarction in the emergency department.

BACKGROUND: Accurate assessment of the patient’s condition in the emergency department (ED) is critical for individuals with acute myocardial infarction (AMI). In this study, point-of-care ultrasound (PoCUS) was utilized to evaluate ventricular wall motion in AMI patients in the ED, aiming to determine its clinical value in early risk stratification and condition assessment. METHODS: A retrospective cohort study was conducted by systematically collecting clinical data from patients who presented to the ED, were ultimately diagnosed with AMI, and underwent cardiac PoCUS examinations. RESULTS: A…

The effect of the liquid motion bubbler timer soothing sensory toy on children's fear and anxiety levels during blood sampling: a randomized clinical trial.

BACKGROUND: Blood sampling is one of the invasive procedures in a hospital setting that can cause fear, anxiety, and stress in children. AIM: The study aimed to determine the effect of the Liquid Motion Bubbler Timer Soothing Sensory Toy on children's fear and anxiety levels during blood sampling. METHODS: The study was conducted with a total of 90 children aged 4-6 years, divided into two groups (45 in the intervention group and 45 in the control group). The data were collected by face-to-face interviews using the "Questionnaire Form", "Children's Fear Scale", and "Children's State Anxiety"…

Equation-of-motion coupled-cluster methods for doubly ionized and doubly electron-attached states with single, double, and triple substitutions: Theory, implementation, and benchmarks.

We present new and computationally efficient implementation of the equation-of-motion (EOM) coupled-cluster methods for doubly ionized (DIP) and doubly electron-attached (DEA) states including single, double, and triple substitutions. In particular, EOM operators include up to 4-hole-2-particle substitutions in EOM-DIP-CCSDT and up to 4-particle-2-holes substitutions in EOM-DEA-CCSDT; both treatments include up to 3-hole-3-particle substitutions in the CC part. These methods have been implemented in the Q-CHEM package using effective and open-mp parallel libtensor and libxm backends. The imple…

Effects of Hip Joint Motion-Style Acupuncture Treatment in Patients with Acute Radiating Leg Symptoms After Traffic Accidents: A Pilot Pragmatic Randomized Controlled Trial.

PURPOSE: We aimed to evaluate the short-term efficacy and safety of early MSAT intervention in patients with acute radiating leg pain following traffic accidents. PATIENTS AND METHODS: This single-center, pragmatic, randomized controlled trial was conducted at a Korean medicine hospital and included 40 patients with radiating leg pain following traffic accidents hospitalized between November 2023 and October 2024. The patients received integrative Korean medicine treatment (IKMT, control) or IKMT combined with MSAT on hospitalization Days 2, 3, and 4. Primary and secondary outcomes, including

Markerless 3D motion capture in return to sport decision making for ACL injured high level athletes: a narrative review with proposed clinical implementation pathway.

BACKGROUND AND OBJECTIVE: Anterior cruciate ligament (ACL) injury remains a career-defining event for high-level athletes, and current return to sport (RTS) criteria often fail to detect residual neuromuscular deficits that drive graft failure and contralateral tears. Three-dimensional (3D) markerless motion capture has emerged as a scalable technology that may address these gaps by quantifying movement quality during sport-specific tasks. The objective of this narrative review is to summarize the current evidence on markerless 3D motion capture in ACL rehabilitation and RTS decision-making, w…

Dynamic motion of bacterial surface pili based on structural analyses of covalently linked complexes formed by tip and shaft pili proteins from Clostridium perfringens.

The pathogenesis and infectivity of Gram-positive bacteria are mediated by many surface proteins covalently attached to the bacterial cell w … The determined structures allowed us to construct a three-dimensional structure model with dynamic motion of C. perfringens pili, and proposed new insights into the mechanism by which CppB is preferentially attached to CppA.

The Evaluation of Combined Diffusion Kurtosis Imaging and Intravoxel Incoherent Motion Diffusion Weighted Imaging in Preoperatively Predicting Sentinel Lymph Node Metastasis of Breast Cancer.

PURPOSE: To evaluate the diagnostic performance of quantitative diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) parameters for preoperative, noninvasive detection of sentinel lymph node metastasis (SLNM) in breast cancer. METHODS AND MATERIALS: Clinicopathologic and MRI data from 61 patients with histologically confirmed breast cancer were reviewed, including 32 patients with SLNM and 29 without SLNM. All patients underwent multi-b-value diffusion-weighted imaging at 3.0 T. Images were analyzed using simplified DKI and biexponential IVIM models on the iCare SpinX work…

Efficacy of Motion-Sensing Game-Assisted Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

BACKGROUND: While motion-sensing game (MSG) platforms provide immersive, real-time feedback environments for rehabilitation, research findings on their effectiveness in chronic obstructive pulmonary disease (COPD) pulmonary rehabilitation remain heterogeneous. OBJECTIVE: This study aims to systematically evaluate the efficacy of MSG-assisted pulmonary rehabilitation for patients with COPD. METHODS: This meta-analysis was conducted in accordance with the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses…

Quantification and Dosimetric Impact of Normal Organ Motion During Adaptive Radiation Therapy Planning Using a 1.5 Tesla Magnetic Resonance-Equipped Linear Accelerator (MR-Linac).

PURPOSE: Patients receiving adaptive magnetic resonance guided radiation therapy (MRgRT) undergo contour modification prior to treatment delivery, which takes 15 to over 60 minutes. We hypothesized that during the time required to create an adaptive MRgRT plan, organ movement will result in dosimetric changes to regional organs at risk (OARs). This study quantifies the dosimetric impact of OAR motion during the time required to perform adaptive MRgRT. METHODS AND MATERIALS: Thirty-one patients with pancreatic adenocarcinoma, prostate adenocarcinoma, hepatocellular carcinoma, and oligo-metasta…

Comparing Effects of Caffeine and Total Motion Release Technique on Cognitive, Neuromuscular, and Anaerobic Function in Semi-Professional Male Sprinters: A Randomized Controlled Trial.

BACKGROUND AND PURPOSE: As sprinting gains popularity, enhancing anaerobic capacity, neuromuscular function, and cognitive performance is crucial. This study evaluated the effects of Total Motion Release (TMR) and caffeine on these functions in male sprinters to optimize performance strategies. METHODS: In this randomized controlled trial, 56 male sprinters were randomly assigned to control, caffeine, TMR, or caffeine plus TMR groups. The Stroop test, Eriksen flanker task, FMS, and Wingate test were used pre- and post-intervention, with effects analyzed via within- and between-group compariso…

First clinical application of Comprehensive Motion Management with 1.5T MR-linac on prostate cancer patients treated with radiotherapy: technical aspects and suggested workflow recommendations.

PURPOSE: MR-guided radiotherapy (MRgRT) on the MR-linac (MRL) with daily online plan adaptation enables better control of inter-fraction variability. Recently, Comprehensive Motion Management (CMM) was introduced for the 1.5T MRL. CMM halts dose delivery when the target moves outside its defined position and allows for target drift corrections, compensating for intra-fraction variability. This study aims to report the first clinical experience with prostate MRgRT using CMM, focusing on intra-fraction motion management and treatment delivery time. MATERIAL AND METHODS: Sixty patients with low-…

Within-session dose-response and between-session carry-over effects of eccentric contractions versus static stretches on range of motion and muscle-tendon mechanics.

PURPOSE: Eccentric resistance training produces substantial increases in maximum joint range of motion (ROM), highlighting its potential as an alternative to static stretching. However, little is known about the short-term effects or associated mechanisms. Therefore, this study compared within-session responses and between-session carry-over effects of eccentric contractions and static stretching in 18 healthy human volunteers. METHODS: Using a counterbalanced crossover design, participants completed four sessions across two conditions: Eccentric contractions (EC1, EC2) and static stretching …

От Лаборатории к жизни: улавливание движения на базе лаборатории и метеориты датчиков на местах для оценки моторных недостатков у людей с множественным склерозом.

Понимание взаимосвязи между лабораторными кинематическими показателями и реальными износимыми данными датчиков позволяет получить ценное представление о моторной дисфункции при множественном склерозе (МС). В этом исследовании изучается корреляция между конкретными контрольными параметрами, полученными с помощью систем улавливания движения при производстве чая и питье, и инерционными единицами измерения запястья и запястья (ИМУ). Разница в длине руки (PL_Diff) в лабораторных задачах выявила сильную корреляцию с расширенной шкалой статуса инвалидности (EDSS) (r=0,64, скорректированный p=0,02), ч

Совпадение в аннотации оригинала
Understanding the relationship between lab-based kinematic metrics and real-world wearable sensor data offers valuable insights into motor dysfunction in multiple sclerosis (MS). This study explores the correlations between task specific metrics derived from motion capture systems during Tea Making and Drinking tasks and wrist-worn inertial measurement units…

Identification of the Distal Dural Ring Using Three-dimensional Motion-sensitized Driven-equilibrium Prepared T1-weighted Fast Spin Echo Imaging: Application to Paraclinoid Aneurysms.

PURPOSE: This study investigated the ability of three-dimentional motion-sensitized driven-equilibrium prepared T1-weighted fast spin echo (3D MSDE-FSE) imaging to identify distal dural rings (DDRs) and paraclinoid aneurysms (ParaC-ANs) and differentiate between intradural and extradural ParaC-ANs and compared it with that of established MR cisternography-based techniques. METHODS: 3D MSDE-FSE images were acquired along with fast imaging employing steady state acquisition (FIESTA), and time-of-flight magnetic resonance angiography (TOF-MRA) on a 3T MRI system in 53 patients with unruptured an…

Concurrent Validity of Wearable Nanocomposite Strain Sensor with Two-Dimensional Goniometer and its Reliability for Monitoring Knee Active Range of Motion in Multiple Participants.

The range of motion (ROM) of joints in the human body is essential for movement and functional performance. Real-time monitoring of joint angles is crucial for confirming pathologic biomechanics, providing feedback during rehabilitation, and evaluating the treatment efficacy. This study aims to evaluate the concurrent validity of a wearable nanocomposite strain sensor with a two-dimensional electrical goniometer and its repeatability for measuring knee ROM during repetitive joint movements in 10 healthy female participants. The participants performed seated knee flexion and extension in three …

Combined Method Comprising Low Burden Physiological Measurements with Dry Electrodes and Machine Learning for Classification of Visually Induced Motion Sickness in Remote-Controlled Excavator.

The construction industry is actively developing remote-controlled excavators to address labor shortages and improve work safety. However, visually induced motion sickness (VIMS) remains a concern in the remote operation of construction machinery. To predict the occurrence and severity of VIMS, we developed a prototype system that acquires multiple physiological signals with different mechanisms under a low burden and detects VIMS from the collected data. Signals during VIMS were recorded from nine healthy adult males operating excavator simulators equipped with multiple displays and a head-mo…