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A Concept Analysis on Failure to Rescue in Maternal Health: Implications for Practice and Policy.

BACKGROUND: Although "Failure to Rescue" (FTR) has been widely studied in general healthcare contexts, and a few clinical specialties, its definition and implications remain underexplored within maternal health, particularly given the heightened risks for marginalized women. The quality measure was retired as a national quality metric before formal adoption into obstetric care, leaving significant gaps in maternal patient safety. High rates of preventable maternal morbidity and mortality, highlight the urgent need to explore and define this concept specifically within maternal health. OBJECTI…

Building linkages between private pharmacies and public facilities to improve diabetes and hypertension care in urban areas of Nepal: a protocol for implementation research.

BACKGROUND: Rapid urbanization is accelerating in low- and middle-income countries (LMICs), which impacts health behaviors and contributes to noncommunicable diseases (NCDs), such as diabetes and hypertension. As primary care services are overstretched, urban residents rely on pharmacies, creating an urgent need to implement evidence-based approaches such as the World Health Organization's Package of Essential Non-communicable Diseases (PEN) to reach low-income households at risk of hypertension and diabetes. This study aims to identify the facilitators and barriers to the adoption, implementa…

Using RE-AIM to inform the adaptation of a clinical decision support application for hypertension disorders of pregnancy: a qualitative study of provider perspectives.

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are significant contributors to maternal morbidity and mortality in the United States, … searchers used a hybrid qualitative approach to deductively apply the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework to data collection, organization, and presentation of results. An inductive approach was then used to identify themes within each RE-AIM domain. RESULTS: Seven participants highlighted the app's potential …

Implementation of antepartum preterm birth interventions: A scoping review.

While antenatal recommendations regarding preterm birth are essential to preventing neonatal morbidity and mortality, implementation of thes … IM framework - a comprehensive evaluative framework composed of 5 dimensions: reach, effectiveness, adoption, implementation, and maintenance. Of the 1178 articles that were screened, 18 were evaluated, and 13 included in this review. The studies were conducted in 12 countries, the majority of which were lower to lower-middle income countries. Designs rang …

Noninvasive Preimplantation Genetic Testing in Recurrent Pregnancy Loss and Implantation Failure: Breakthrough or Overpromise?

Background: Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) are significant challenges in reproductive medicine. For … es specifically in RPL and RIF cohorts. As such, niPGT is not yet ready to be a standalone clinical adoption in RPL and RIF cases. However, it may serve as a valuable adjunct for rescue scenarios following biopsy failure or for ethical reasons. Wider Implications: The integration of niPGT with artificial intelligence, time-lapse imaging, and multi-omics pr …

ARBOR-Telehealth study: an examination of telerehabilitation to improve function and reduce opioid use in persons with chronic low back pain in rural communities - protocol of a pragmatic, individually randomised group treatment trial.

INTRODUCTION: Chronic low back pain (LBP) imposes significant burden on patients, healthcare systems and society. Physical therapy is a cost … , participant self-report and medical chart abstraction. Implementation outcomes are acceptability, adoption, feasibility and fidelity of our treatment approach guided by the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework and assessed using surveys, semi-structured interviews and key performance metrics. ETHICS AND DISSE …

Implementation of an Australian helpline for low back pain: protocol of a type 2 hybrid effectiveness-implementation trial.

INTRODUCTION: Low back pain (LBP) is the leading contributor to disability globally. It has a substantial impact on the lives of those who e … gn process, the Practical Robust Implementation Sustainability Model, and the Reach, Effectiveness, Adoption, Implementation and Maintenance framework-to guide the codesign and development, implementation and evaluation of an upgraded helpline for people with LBP. The codesign process involves key stakeholders, including consumers and clinicians, to inform …

Diagnostic Accuracy and Clinical Impact of Handheld Point-of-Care Ultrasound in Pediatric Odontogenic Infections: A Prospective Cohort Study.

BACKGROUND: Pediatric odontogenic infections pose significant diagnostic challenges, particularly in distinguishing between cellulitis and a … ssociated with a lower annualized admission rate and demonstrated moderate diagnostic accuracy. Its adoption was associated with a notable reduction in hospitalizations, suggesting its potential for alleviating ED overcrowding, reducing healthcare costs, and minimizing pediatric stress. Wider adoption, supported by standardized training, could enhance heal …

Experiences of undetectable = untransmittable among couples with different HIV serostatus: a qualitative study in Tanzania and Uganda.

BACKGROUND: HIV serodifferent couples where one partner is living with HIV and the other is not, remain a key population for HIV prevention. Maintaining an undetectable viral load eliminates the risk of sexual HIV transmission, this principle is often summarised as undetectable = untransmittable (U = U). However, the extent to which this principle is understood and utilised by serodifferent couples remains unclear. This study aimed to explore both partners’ perceptions, experiences and adoption of U = U within their relationships. METHODS: We conducted an exploratory qualitative study using in…

Factors that shape the integration of HIV and TB services in Zomba District, Malawi.

BACKGROUND: The co-occurrence of HIV and tuberculosis (TB) presents significant challenges for effective healthcare delivery and patient out … sing the Atun framework, which groups factors shaping integration around the problem, intervention, adoption system, health system characteristics and broad context, was employed. RESULTS: Increased workload among health workers and side effects among patients were reported barriers given the nature of the problem. The benefits of integrating HIV/TB servi …

Analysis of value-based healthcare (VBHC) framework by incremental cost-effectiveness of surgical and therapeutic interventions: a retrospective study at tertiary private health group.

BACKGROUND: Rising healthcare costs have led to the adoption of value-based healthcare (VBHC), emphasizing patient outcomes and cost efficiency. This study evaluates VBHC in a tertiary private health group, focusing on cost-effectiveness using the median incremental cost-effectiveness ratio (ICER). METHODOLOGY: A retrospective cohort study analyzed 1576 patients treated between 2021 and 2024 in Almoosa Health Group, Al-Ahsa, Saudi Arabia. Patients underwent surgeries and therapies for Anterior Cruciate Ligament (ACL) injuries, knee and hip replacements, cerebral palsy, low back pain, and multi…

Оценка потенциала SNfL в качестве биомаркера в управлении MS в Соединенном Королевстве: выводы обследования SUNLIT.

Текущие данные подтверждают использование NfL в качестве биомаркера для нейроаксональных повреждений при множественном склерозе (MS), однако для оптимального управления пациентами необходим перевод с клинических испытаний на клиническую практику. МЕТОДЫ: Обследование " SUNLIT " , проводимое под руководством " Новартис " в сотрудничестве с ведущими экспертами в области медицины, было направлено на оценку полезности " SNfL " в качестве биомаркера для MS в рамках обычной клинической практики в Соединенном Королевстве. Обследование включало в себя ключевые вопросы для

Совпадение в аннотации оригинала
BACKGROUND: Current evidence supports the use of NfL as a biomarker for neuroaxonal damage in multiple sclerosis (MS), but translation from … and potential impact of sNfL testing on the management of MS, and the role of guidelines for on the adoption of sNfL into clinical practice for MS management across the UK. RESULTS: A total of 86 clinicians (neurologists specialising in MS, n = 45; MS nurse practitioners, n = 41) from the UK participated in the survey. All HCPs responded to all the survey …

Systematic Implementation of Effective Quality Assurance Processes for the Assessment of Radiation Target Volumes in Head and Neck Cancer.

PURPOSE: Significant heterogeneity exists in clinical quality assurance (QA) practices within radiation oncology departments, with most char … 12.6%; P = .039). Frequency of major modification requests significantly decreased over time after adoption of prospective peer contour review, with no red grades occurring >6 months after adoption. CONCLUSIONS: This study highlights the importance of prospective peer contour-review implementation into systematic clinical QA processes for HNC. Physician …

The UPFRONT project: tailored implementation and evaluation of a patient decision aid to support shared decision-making about management of symptomatic uterine fibroids.

OBJECTIVE: To evaluate implementation of a patient decision aid for symptomatic uterine fibroid management to improve shared decision-making at five clinical settings across the United States. METHODS: We used a type 3 hybrid effectiveness-implementation stepped-wedge design and the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) planning and evaluation framework. We conducted clinician training, monthly reach tracking with feedback to site clinical leads, patient and clinician surveys, and visit audio-recordings. Implementation strategies included assessment of organizat…

Implementation of a rural emergency department-initiated buprenorphine program in the mountain west: a study protocol.

BACKGROUND: Opioid related overdose morbidity and mortality continue to significantly impact rural communities. Nationwide, emergency depart … ures of an ED-initiated buprenorphine program in the rural Mountain West. The Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework outlines intervention assessments. The primary outcome is implementation measured by ED-initiated buprenorphine protocol core components. Reach, adoption, and maintenance are secondary outcomes. Ex …

The Support Hospital Opioid Use Disorder Treatment (SHOUT) Texas program implementation strategy for expanding treatment for hospitalized adults with opioid use disorder.

INTRODUCTION: In 2017, we launched the "B-Team" (buprenorphine team), the first hospitalist-led opioid use disorder (OUD) treatment program … rams (REP) strategy with statewide telementoring delivered via Project ECHO. To evaluate the reach, adoption, and impact of SHOUT Texas, we assessed: 1) participating hospitals (adoption); 2) patients screened for OUD (impact); 3) patients started on medications for OUD (impact); 4) patients discharged with coordinated outpatient care (impact); 5) provider …

Using Video Technology and AI within Parkinson's Disease Free-Living Fall Risk Assessment.

Falls are a major concern for people with Parkinson's disease (PwPD), but accurately assessing real-world fall risk beyond the clinic is cha … ll risk. Second, we investigated the perceptions of PwPD via a focus group discussion regarding the adoption of video technologies and AI during their everyday lives to better inform their own fall risk. This second aspect of the study is important as, traditionally, there may be clinical and patient apprehension due to ethical and privacy concerns on the …

The evolution of ventral intermediate nucleus targeting in MRI-guided focused ultrasound thalamotomy for essential tremor: an international multi-center evaluation.

BACKGROUND: The ventral intermediate nucleus (VIM) is the premiere target in magnetic resonance-guided focused ultrasound (MRgFUS) thalamoto … = 22) of centers based their targeting on anatomical landmarks rather than tractography. Increased adoption of tractography in clinical practice and/or for research was noted, changing from 34.6% to 78.3%. There was a statistically significant change in VIM-TAs in the superior-inferior plane across the study period; the percentage of VIM-TAs positioned 2 …

Development of a Management App for Postviral Fibromyalgia-Like Symptoms: Patient Preference-Guided Approach.

BACKGROUND: Persistent fibromyalgia-like symptoms have been increasingly reported following viral infections, including SARS-CoV-2. About 30% of patients with post-COVID-19 syndrome fulfill the fibromyalgia criteria. This complex condition presents significant challenges in terms of self-management. Digital health interventions offer a viable means to assist patients in managing their health conditions. However, the challenge of ensuring their widespread adoption and adherence persists. This study responds to this need by developing a patient-centered digital health management app, incorporati…

Contemporary media campaigns for musculoskeletal pain: A systematic review and meta-analysis with social marketing benchmarking.

Musculoskeletal pain is a global public health problem. Social marketing aims to increase adoption of desired behaviours in target audiences and may uncover new strategies to improve uptake of helpful pain-related behaviours at the population-level. We systematically evaluated effects of contemporary mass media campaigns targeting musculoskeletal pain and used social marketing benchmarking to explore strategies associated with campaign success. Published evaluations of campaigns involving an online/digital component and a comparator/control condition were eligible. The primary outcome was popu…