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259 Patients with DCIS of the breast applying USC/Van Nuys prognostic index: a retrospective review with long term follow up.

BACKGROUND: The Van Nuys Prognostic Index (VNPI) is a simple score for predicting the risk of local recurrence (LR) in patients with Ductal … mph Node Biopsy, four were found to have micrometastases and all of them had a previous Directional Vacuum Assisted Biopsy. CONCLUSIONS: Although in our series there is not a significant difference in LR rates by the parameter of age, the new USC/VNPI is still a simple and reliable scoring system for therapeutic management of DCIS. We did not find any s …

[Clinical effects of antibiotic bone cement and VSD combined with free chimeric anterolateral thigh perforator myocutaneous flaps for sequential treatment of diabetic calcaneal osteomyelitis wounds].

Objective: To explore the clinical effects of antibiotic bone cement and vacuum sealing drainage (VSD) combined with free chimeric anterolateral thigh perforator myocutaneous flaps for sequential treatment of diabetic calcaneal osteomyelitis wounds. Methods: This study was a retrospective investigation of case series. From June 2019 to June 2024, 12 patients with diabetic calcaneal osteomyelitis wounds who met the inclusion criteria were admitted to the Department of Burns and Plastic Surgery of Xiangya Hospital of Central South University, including 7 males and 5 females, aged 40 to 65 years.…

Medical methods for first trimester abortion.

BACKGROUND: Surgical abortion by vacuum aspiration or dilatation and curettage has been the method of choice for early pregnancy termination since the 1960s. Medical abortion became an alternative method of first trimester pregnancy termination with the availability of prostaglandins in the early 1970s and anti-progesterones in the 1980s. The most widely researched drugs are prostaglandins (PGs) alone, mifepristone alone, methotrexate alone, mifepristone with prostaglandins and methotrexate with prostaglandins. OBJECTIVES: To compare different medical methods for first trimester abortion. SE…

Randomised preference trial of medical versus surgical termination of pregnancy less than 14 weeks' gestation (TOPS).

OBJECTIVES: To determine the acceptability, efficacy and costs of medical termination of pregnancy (MTOP) compared with surgical termination … tol 400 micrograms 2 hours before the procedure. STOP was performed under general anaesthesia using vacuum aspiration. MTOP: all women < 14 weeks' gestation were given mifepristone 200 milligrams orally, returning 36-48 hours later for misoprostol. OUTCOME MEASURES: Main outcome measure was acceptability of TOP method. Secondary outcome measures include …

[Clozapine and pregnancy].

UNLABELLED: This article reviews the relations between clozapine and pregnancy. Six case reports are identified in the literature of pregnan … udies can explain how clozapine affects the labor exactly. Some case studies report use of forceps, vacuum or cesarean. CONVULSIONS: Stoner (1997) described neonatal convulsions 8 days after birth. The mother was receiving 350 mg of clozapine, but also lorazepam and haloperidol during her pregnancy. The newborn withdrawal of lorazepam can increase the r …

Evidence base to inform health service configuration for abortion provision: the SACHA (Shaping Abortion for Change) multi-component study.

BACKGROUND: Significant changes to the nature and context of abortion provision are taking place in the United Kingdom. Empirical evidence i … permit healthcare professionals other than clinicians to prescribe abortion medication and perform vacuum aspiration; and to allow abortion to be provided in additional suitable resourced and equipped facilities, notably community sexual and reproductive health services. Training was considered necessary to equip health professionals for an extended rol …

Incidence and Independent Risk Factors of Spinal Infection After Vertebral Augmentation: A Multicenter Propensity-Matched Case-Control Study.

OBJECTIVE: This study aimed to determine the incidence of spinal infection after vertebral augmentation (SIAVA) and identify its independent risk factors. METHODS: This multicenter, retrospective case-control study included patients who underwent percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fractures at 4 centers between January 2015 and December 2021. Each SIAVA case was matched with 3 controls using propensity score matching based on demographic and clinical variables. LASSO (least absolute shrinkage and selection operator) regression was used for variabl

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… The fluid sign in the fractured vertebral body was defined as the presence of an intravertebral vacuum cleft with fluid filling as the predominant feature. … As a result, T2-weighted MRI sequences typically show high signal, with an 81% probability that the intravertebral vacuum cleft in the thoracolumbar segment is filled with liquid [ 34 ]. …

Optimizing percutaneous vertebroplasty: extra-facet puncture for osteoporotic vertebral compression fractures.

PurposeTo assess the safety and efficacy of the extra-facet puncture technique applied in unilateral percutaneous vertebroplasty (PVP) for treating osteoporotic vertebral compression fractures.MethodsDemographics (age, gender, body mass index and underlying diseases) were recorded for analyzing. Visual analog scale (VAS) and Oswestry Disability Index (ODI) scores as well as their corresponding minimal clinically important difference (MCID) were used to evaluate clinical outcomes. The segmental kyphotic angle, the vertebral compression ratio and bone cement distribution pattern were evaluated b

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… Studies targeting the causes of residual back pain following PVP surgery have identified several risk factors such as low bone density, low bone cement volume, uneven bone cement distribution, intravertebral vacuum cleft and posterior fascia oedema et al. [ 12 – 16 ]. … Preoperative VAS, ODI, posterior fascia oedema ratio, intravertebral vacuum cleft ration, segmental kyphotic angle and vertebral compression ratio was essentially identical between the two groups (Table 2 , p > 0.05). …

[A prospective randomized controlled study of antibiotic bone cement in the treatment of diabetic foot ulcer].

Objective: To investigate the clinical effects and related mechanism of antibiotic bone cement in treating diabetic foot ulcer (DFU). Method … ensuring the patency of at least one main inferior genicular artery in each patient, the continuous vacuum sealing drainage was performed for 3-5 days after thorough debridement. Thereafter, the wounds in antibiotic bone cement group were treated with gentamicin-laden bone cement, and the wounds in silver sulfadiazine group were treated with silver sulfa …

Superior Pubic Ramus Screw Placement During Complex Acetabular Revision: Acetabular Distraction for Treatment of Pelvic Discontinuity.

UNLABELLED: Insertion of a superior pubic ramus screw may be indicated for the treatment of a chronic pelvic discontinuity when utilizing ac … ding neurovascular structures. ACRONYMS AND ABBREVIATIONS: OR = operating roomf/u = follow-upvac = vacuum-assisted closureRSA = radiostereometric analysis.

Closed Reduction of Pediatric Distal Radial Fractures and Epiphyseal Separations.

BACKGROUND: Sedated, closed reduction of a displaced distal radial fracture followed by cast immobilization is indicated in cases of unaccep … inside edges of the cast at the fracture site.Keeping cast saw blades sharp, using saws attached to vacuum devices, and cooling the blade while in use can prevent cast-saw burns.Zip sticks can be utilized to protect the skin but can sometimes be difficult to get under the cast.It is important to remember that swelling will occur following fracture reduct …

Localized Breast Amyloidosis Associated with Sjörgren Syndrome.

Sjörgren syndrome is a systemic autoimmune disease that is rarely associated with amyloid deposits, and in most reported cases, these deposits are localized to a single organ. Amyloidosis of the breast is a rare and unexpected finding, and only 5 case series with 63 patients have been published in the past 40 years. To date, only 6 cases have been reported in which Sjörgren syndrome is associated with amyloid deposits in the breast. A 61-year-old female diagnosed with Sjörgren syndrome underwent a breast needle core biopsy for calcifications. Microscopic examination revealed amyloid deposits i

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… Case Presentation A 61-year-old female presented with calcifications of the left breast on mammography and underwent stereotactic vacuum-assisted core biopsy. … H&E-stained sections of the 9-gauge vacuum-assisted breast core biopsy showed benign breast parenchyma with amyloid deposits in various stages (Figures 1(a) and 1(b) ). Multiple breast lobules had marked thickening of periductular basement membranes by eosinophilic deposits ( Figure 1(b) ). …

Нейрогенная желудочно-кишечная, мочевая и сексуальная дисфункция при множественном склерозе: многодисциплинарная основа для клинической практики.

Нейрогенные желудочно-кишечные, мочевые и сексуальные симптомы широко распространены у людей с множественным склерозом и существенно ухудшают качество жизни, повседневное функционирование и психосоциальное благополучие. Несмотря на их частотность и клиническую актуальность, управление по-прежнему носит разрозненный характер по различным специальностям, тесная взаимосвязь между этими симптомами зачастую игнорируется, а у клинических работников отсутствует прагматическая основа, адаптированная к различным условиям здравоохранения. Этот обзор преобразует нынешние данные в прагматичную модель уход

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… If pharmacological therapy is not effective, vacuum-constriction devices can be used as an add-on option to PDE5i. 59 Vacuum devices are used in conjunction with penile rings to maintain erection and should not be used for more than 30 min to avoid risk of ischemia. … An open trial of vacuum penile tumescence: constriction therapy for neurological impotence. Paraplegia. 1992;30(8):550–553. doi: 10.1038/sc.1992.113. 60. Hirsch I.H., Smith R.L., Chancellor M.B., Bagley D.H., Carsello J., Staas W.E., Jr. …

Clinical and cost-effectiveness of negative pressure wound therapy versus usual care for surgical wounds healing by secondary intention: the SWHSI 2 pragmatic RCT.

BACKGROUND: Surgical wounds healing by secondary intention occur if a surgical wound is not closed or dehisces following primary closure. Surgical wounds healing by secondary intention are common and adversely affect patients' quality of life. Treatment is often prolonged, complex and expensive. Negative pressure wound therapy applies a controlled vacuum to the wound and is increasingly used to promote surgical wound healing by secondary intention despite limited rigorous evidence for the clinical and cost-effectiveness of negative pressure wound therapy to augment surgical wound healing by se…

[Treatment methods of upper limbs with destructive electric burns and its clinical efficacy].

Objective: To investigate the treatment methods of upper limbs with destructive electric burns and its clinical efficacy. Methods: A retrosp … after tissue flap transplantation, which gradually healed after surgical debridement combined with vacuum sealing drainage treatment. At the last follow-up, the stump of two affected limbs healed well after amputation; 18 affected limbs that were successfully salvaged all survived well, of which 8 affected limbs had good recovery of finger flexion and e …

Spinal Fusion with Sacral Alar Iliac Pelvic Fixation in Severe Neuromuscular Scoliosis.

UNLABELLED: Neuromuscular scoliosis is characterized by rapid progression of curvature during growth and may continue to progress following … ity.Use a T-square to verify adequate spinopelvic alignment9.Postoperatively, the use of incisional vacuum-assisted closure can decrease soiling in these patients. ACRONYMS AND ABBREVIATIONS: SAI = Sacral alar iliacCP = Cerebral palsyAIS = Adolescent idiopathic scoliosisSMA = Spinal muscular atrophyIONM = Intraoperative neuromonitoringGMFCS = Gross Moto …

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.

BACKGROUND: Newborn infants have the ability to experience pain. Hospitalised infants are exposed to numerous painful procedures. Healthy newborns are exposed to pain if the birth process consists of assisted vaginal birth by vacuum extraction or by forceps and during blood sampling for newborn screening tests. OBJECTIVES: To determine the efficacy and safety of paracetamol for the prevention or treatment of procedural/postoperative pain or pain associated with clinical conditions in neonates. To review the effects of various doses and routes of administration (enteral, intravenous or rectal)…

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.

BACKGROUND: Newborn infants have the ability to experience pain. Hospitalised infants are exposed to numerous painful procedures. Healthy newborns are exposed to pain if the birth process consists of assisted vaginal birth by vacuum extraction or by forceps and during blood sampling for newborn screening tests. OBJECTIVES: To determine the efficacy and safety of paracetamol for the prevention or treatment of procedural/postoperative pain or pain associated with clinical conditions in neonates. To review the effects of various doses and routes of administration (enteral, intravenous or rectal)…

Midwife-led continuity models versus other models of care for childbearing women.

BACKGROUND: Midwives are primary providers of care for childbearing women around the world. However, there is a lack of synthesised informat … es (i.e. regional analgesia (epidural/spinal), caesarean birth, instrumental vaginal birth (forceps/vacuum), spontaneous vaginal birth, intact perineum, preterm birth (less than 37 weeks) and all fetal loss before and after 24 weeks plus neonatal death using the GRADE methodology: all primary outcomes were graded as of high quality.For the primary outcom …

Midwife-led continuity models versus other models of care for childbearing women.

BACKGROUND: Midwives are primary providers of care for childbearing women around the world. However, there is a lack of synthesised informat … s (i.e., regional analgesia (epidural/spinal), caesarean birth, instrumental vaginal birth (forceps/vacuum), spontaneous vaginal birth, intact perineum, preterm birth (less than 37 weeks) and overall fetal loss and neonatal death (fetal loss was assessed by gestation using 24 weeks as the cut-off for viability in many countries) using the GRADE methodolo …