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Medical methods for first trimester abortion.

BACKGROUND: Surgical abortion up to 63 days by vacuum aspiration or dilatation and curettage has been the method of choice since the 1960s. Medical abortion became an alternative method of first trimester pregnancy termination with the availability of prostaglandins in the early 1970s and anti-progesterones in the 1980s. The most widely researched drugs are prostaglandins (PGs) alone, mifepristone alone, methotrexate alone, mifepristone with prostaglandins and methotrexate with prostaglandins. OBJECTIVES: To compare different medical methods for first trimester abortion. SEARCH STRATEGY: The…

Medical methods for first trimester abortion.

BACKGROUND: Surgical abortion up to 63 days by vacuum aspiration or dilatation and curettage has been the method of choice since the 1960s. Medical abortion became an alternative method of first trimester pregnancy termination with the availability of prostaglandins in the early 1970s and anti-progesterones in the 1980s. The most widely researched drugs are prostaglandins (PGs) alone, mifepristone alone, methotrexate alone, mifepristone with prostaglandins and methotrexate with prostaglandins. OBJECTIVES: To compare different medical methods for first trimester abortion. SEARCH STRATEGY: The…

Efficacy and safety of tunneled pleural catheters in adults with malignant pleural effusions: a systematic review.

BACKGROUND: Malignant pleural effusions (MPE) are a frequent cause of dyspnea and discomfort at the end of cancer patients' lives. The tunneled indwelling pleural catheter (TIPC) was approved by the FDA in 1997 and has been investigated as a treatment for MPE. OBJECTIVE: To systematically review published data on the efficacy and safety of the TIPC for treatment of MPE. DESIGN: We searched the MEDLINE, EMBASE, and ISI Web of Science databases to identify studies published through October 2009 that reported outcomes in adult patients with MPE treated with a TIPC. Data were aggregated using su

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… The oldest study, published in 1994, used a tube known as the Tenckhoff catheter, which is also a small-bore flexible catheter that was tunneled into the pleural space. 20 One study employed a reusable plastic pump to drain pleural fluid instead of the standard vacuum drainage bottles designed for use … Putnam et al. found that early mean hospital charges were significantly lower in patients receiving a TIPC placed in the outpatient setting as compared to those who were treated as an inpatient with either chest tube or TIPC. 22 As the biggest long-term cost of the TIPC is that of the disposable vacuum …

Imaging of vertebral fractures.

Vertebral fracture is a common clinical problem. Osteoporosis is the leading cause of non-traumatic vertebral fracture. Often, vertebral fractures are not clinically suspected due to nonspecific presentation and are overlooked during routine interpretation of radiologic investigations. Moreover, once detected, many a times the radiologist fails to convey to the clinician in a meaningful way. Hence, vertebral fractures are a constant cause of morbidity and mortality. Presence of vertebral fracture increases the chance of fracture in another vertebra and also increases the risk of subsequent hip

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… The intravertebral vacuum cleft: A sign of ischemic vertebral collapse. Radiology. 1978;129:23–9. doi: 10.1148/129.1.23. 50. Samelson EJ, Christiansen BA, Demissie S, Broe KE, Zhou Y, Meng CA, et al. … Intravertebral vacuum cleft: Changes in content after supine positioning. Radiology. 1993;187:483–7. doi: 10.1148/radiology.187.2.8475295. 55. Uetani M, Hashmi R, Hayashi K. Malignant and benign compression fractures: Differentiation and diagnostic pitfalls on MRI. …

To Evaluate Effect of Airborne Particle Abrasion using Different Abrasives Particles and Compare Two Commercial Available Zirconia on Flexural Strength on Heat Treatment.

BACKGROUND AND OBJECTIVE: The popularity of ceramic restorations can be attributed to its life-like appearance, durability and biocompatibil … , heating rate of 100°c/ min, ending at a temperature of 1000°C and 15 minutes holding time without vacuum for the specimens in the group 4, 5, 9 and 10. Airborne-particle abrasion mimicking the preparation for cementation was applied to the lower surfaces with 50 µm alumina and silica coated alumina particles for the specimens in the groups 6, 7, 8, 9 a …

Nanomedicine: Principles, Properties, and Regulatory Issues.

Several scientific areas have benefited significantly from the introduction of nanotechnology and the respective evolution. This is especially noteworthy in the development of new drug substances and products. This review focuses on the introduction of nanomedicines in the pharmaceutical market, and all the controversy associated to basic concepts related to these nanosystems, and the numerous methodologies applied for enhanced knowledge. Due to the properties conferred by the nanoscale, the challenges for nanotechnology implementation, specifically in the pharmaceutical development of new dru

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… The main disadvantage of these methods is the operation under high-vacuum, although recently with the development of cryo-SEM sample dehydration has been prevented under high-vacuum conditions (Linsinger et al., 2012 ; Contado, 2015 ; Hodoroaba and Mielke, 2015 ). … parameters analyzed | Limitations Transmission Electron Microscopy | An electron beam interacts and passes through the sample and the scattered electrons are focused to create an image. | Particle size and size distribution; Shape; Agglomeration; Aggregation; Crystal structure. | Operation in high-vacuum …

Новые знания о генетической основе и транскриптомном освещении вирулентности в вариантах Pseudomonas shiringae pv. actinidiae.

Псевдомонас сирингаэ pv. actindiae (Psa) является причинным агентом киви бактериального канцера, но факторы, влияющие на его патогенность в природных условиях, остаются малоизученными. В этом исследовании мы изолировали two Пса, штаммы G126 и G282, из зараженных киви садов в китайской провинции Гуйчжоу. Оба изолируют, отнесенные к категории Psa-biovar 3, были подтверждены через Psa3-specific и филогеномический анализ. Анализы патогенности на киви-фруктовых листьях и ветках «Хонгян» показали значительное сокращение числа некротических пятен и уменьшение размеров повреждений при инфекции G282 по

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… (A) three variable virulence types of Psa-biovar 3 (Psa3) were infiltrated into the sterilized “Hongyang” leaves under vacuum and placed in 0.5% water agar medium in triplicate. Photographs were taken at 5 dpi. … Determining the cause of reduction in pathogenicity of Psa3 strain G126 (A) G1 and G126 were vacuum infiltrated in sterilized Kiwi branches, and 10 µL of bacterial solution was dropped onto the wound, with sterile water as a control. …

State-of-the-art imaging for diagnosis of metastatic bone disease.

Metastatic bone disease (MBD) is common-it is detected in up to 65-75% of patients with breast or prostate cancer, in over 35% of patients with lung cancer; and almost all patients with symptomatic multiple myeloma have focal lesions or a diffuse bone marrow infiltration. Metastatic bone disease can cause a variety of symptoms and is often associated with a poorer prognosis, with high social and health-care costs. Population-based cohort studies confirm significantly increased health-care utilization costs in patients presenting with cancer with MBD compared with those without MBD. The prolong

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… (CT) or fluid sign (MRI) in vertebral body Low signal intensity band on T1- and T2-weighted images “fluid sign” or intravertebral “vacuum cleft sign” Tumor permeation of vertebral border, focal paravertebral growth Table 8 Differentiating between osteoporotic and metastatic vertebral body fractures … (CT) or fluid sign (MRI) in vertebral body Low signal intensity band on T1- and T2-weighted images “fluid sign” or intravertebral “vacuum cleft sign” | Tumor permeation of vertebral border, focal paravertebral growth In acute vertebral fractures with extensive edema in the bone marrow, the addition …

Диет модернизирует терапевтическое воздействие диметилфумарата, поддерживаемого иммунометаболическим нейтрофильным рецептором HCAR2.

Монометилфумарат (ММФ) и его пронаркодиметилфумарат (ДМП) в настоящее время являются наиболее широко используемыми агентами для лечения множественных склерозов (МС). Однако не все пациенты получают помощь от ДМФ. Мы предположили, что переменная реакция пациентов может быть связана с их питанием. В поддержку этой гипотезы мыши, подвергшиеся экспериментальному аутоиммунальному энцефаломиэлиту (EAE), являющемуся моделью MS, не пользовались лечением DMF при питании богатой лауричной кислотой диетой. В противоположность этому, мыши на нормальном питании чау (NC) и даже мыши на рационе с высоким сод

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… After incubation and centrifugation, supernatants were dried under vacuum and reconstituted in 25 µl methanol/acetonitrile (1:1, vol/vol) for LC-MS/MS analysis. … After transferring the supernatant to a fresh tube, NaOH (0.8 M, 5 μl) was added, followed by evaporation of solvents via vacuum centrifugation. …

The Herba Patriniae (Caprifoliaceae): A review on traditional uses, phytochemistry, pharmacology and quality control.

ETHNOPHARMACOLOGICAL RELEVANCE: Herba Patriniae has been used for thousands of years in China as a traditional Chinese medicine with heat-clearing and detoxicating effects. It is applied widly for the treatment of rheumatoid arthritis, diarrhea, acute hepatitis, pelvic inflammatory disease and ulcerative colitis in clinic. Two species, namely Patrinia scabiosaefolia Fisch. (PS) and Patrinia villosa Juss. (PV) from the Caprifoliaceae family, are considered as Herba Patriniae in the pharmaceutical industry. AIM OF THE REVIEW: This paper aims to comprehensively outline the traditional uses, bota

Is There a Role of Cupping Therapy in the Treatment of Carpal Tunnel Syndrome in Primary Care Setting?

Carpal tunnel syndrome (CTS) is a clinical syndrome, which causes significant morbidity. It is currently managed conservatively with splinting or steroidal injections. Where conservative management is unsatisfactory, surgical decompression is carried out. Because of dangerous complications of surgical procedures and increasing economical burden of CTS condition, safe, traditional, cost effective conservative adjunct option is being evaluated in this review article. Cupping therapy is an ancient but increasingly popular therapy for a variety of pathologies. Studies over the last decade have ind

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… In the dry cupping skin is pulled into the cup via vacuum pressure whereas in the wet cupping, scarification is also carried out in order to draw blood into the cup (Figure 1 ) [ 19 ]. Figure 1 Cupping instrument. … In 26 patients of study population, the trapezius muscle area for wet cupping therapy, which consists of scarification (puncturing) of the skin, application of vacuum cup and mechanical suction, was chosen. Twenty-two controls were treated by application of heating pad. …

[Management strategy of femoral artery pseudoaneurysm combined with infectious wounds].

Objective: To investigate the surgical treatment methods of femoral artery pseudoaneurysm combined with infectious wounds and to evaluate th … unds that could be sutured were treated with tension reduction suture and extracutaneous continuous vacuum sealing drainage (VSD), while large wounds that could not be sutured were treated with VSD to control infection. In the secondary operation, tension reduction suture was performed to repair the wounds that could be sutured; large wounds were repaire …

Management, Functional Outcomes, and Quality of Life After Development of Pelvic Sepsis in Patients Undergoing Re-Do Ileal Pouch Anal Anastomosis.

BACKGROUND: The data on management and outcomes of pelvic sepsis after re-do IPAA are scarce. OBJECTIVE: The aim of this study is to report … inage and mushroom catheter placement (n = 1), mushroom catheter placement (n = 1), and endoluminal vacuum-assisted closure (n = 1). Average number of bowel movements, urgency, incontinence, pad use, and seepage were comparable between the pelvic sepsis and no pelvic sepsis groups ( p > 0.05). Lifestyle alterations, Cleveland Global Quality of Life score …

[Perioperative management of wounds associated with secondary sternal osteomyelitis and/or mediastinitis after sternotomy and its clinical effects].

Objective: To investigate the perioperative management of wounds associated with secondary sternal osteomyelitis and/or mediastinitis after … sternal defect. After the skin in the donor area was closed by tension-relieving suture, continuous vacuum sealing drainage was performed, and continuous even infusion and lavage were added 24 hours later. The thorax was fixed with an armor-like chest strap, the patients were guided to breathe abdominally, with both upper limbs fixed to the lateral chest …

Charge transport in nanoscale junctions.

Understanding the fundamentals of nanoscale charge transfer is pivotal for designing future nano-electronic devices. Such devices could be based on individual or groups of molecular bridges, nanotubes, nanoparticles, biomolecules and other 'active' components, mimicking wire, diode and transistor functions. These have operated in various environments including vacuum, air and condensed matter, in two- or three-electrode configurations, at ultra-low and room temperatures. Interest in charge transport in ultra-small device components has a long history and can be dated back to Aviram and Ratner'…

Health Risks from Microplastics in Intravenous Infusions: Evidence from Italy, Spain, and Ecuador.

The rising incidence of microplastics (MPs) is a possible health risk to humans. The present study aims to analyze the presence of MPs in intravenous (IV) infusions and compare MP concentrations from multiple brands. The IV solutions of 29 medical devices (IV-MDs) from seven brands commercialized in Ecuador, Spain, and Italy have been selected under specific consideration to carry out the study. The detection of MPs has been quite obvious in almost all of the samples from brands in the mentioned countries. MP concentrations ranged from 9 to 20 MPs/L in glass containers to 166-299 MPs/L in plas

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… Within the vacuum cabinet, the full volume of every IV-MD was vacuum filtered. … It used high-vacuum modes for samples with the highest resolution and low-vacuum modes for wet or non-conductive surfaces. It used backscattered secondary (composition, topography, and shadowing) electron detectors. …

Total Hip Replacement with Use of the French Paradox Cementing Technique for a Shortened Charnley-Kerboull Stem via a Bikini Approach.

BACKGROUND: The "French Paradox" technique, one of the various femoral cementing techniques in total hip replacement, was developed by Marce … adox technique is easy, cost-effective, and reproducible. There is no need for a tip centralizer or vacuum cement preparation, and the femoral preparation closely resembles that for a cementless implant, making the technique more intuitive for surgeons already experienced with cementless hip arthroplasty. EXPECTED OUTCOMES: El Masri et al. observed that …

[Phage therapy analysis of effectiveness in comorbid patients with wounds and surgical infections of various etiology based on the results of a comparative clinical study].

BACKGROUND: The continued importance of addressing the issue of treating purulent wounds and surgical infections of different origins and lo … s a combination of general and local phage therapy by various delivery routes (in particular, using vacuum devices with the possibility of instillation). CONCLUSION: The principles of treatment of soft tissues and bones severe surgical infection in comorbid patients in our country are still based on the method of active surgical treatment of wounds deve …

Gynaecological and obstetric management of women with inherited bleeding disorders.

OBJECTIVE: The prevalence of bleeding disorders, notably von Willebrand disease (vWD), among adult women with objectively documented menorrh … here is access to consultants in obstetrics, anesthesiology, hematology, and pediatrics (III-C). 9. Vacuum extraction, forceps, fetal scalp electrodes, and fetal scalp blood sampling should be avoided if the fetus is known or thought to be at risk for a congenital bleeding disorder. A Caesarean section should be performed for obstetrical indications only …

Gynaecological and obstetric management of women with inherited bleeding disorders.

OBJECTIVE: The prevalence of bleeding disorders, notably von Willebrand disease (vWD), among adult women with objectively documented menorrh … here is access to consultants in obstetrics, anesthesiology, hematology, and pediatrics (III-C). 9. Vacuum extraction, forceps, fetal scalp electrodes, and fetal scalp blood sampling should be avoided if the fetus is known or thought to be at risk for a congenital bleeding disorder. A Caesarean section should be performed for obstetrical indications only …