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[Research progress on analytical methods for the determination of hexachlorobutadiene].

Hexachlorobutadiene (HCBD) is one of persistent organic pollutants (POPs) listed in Annex A and Annex C of the Stockholm Convention in 2015 … nother key step for obtaining high recoveries of HCBD. Disk SPE involving the combination of a high-vacuum pump and a low-humidity atmosphere is an effective way to eliminate the residual water. In addition, a micro SPE method using functionalized polysulfone membranes as sorbents and employing ultrasonic desorption was developed for extracting HCBD from …

Cervical ripening before first trimester surgical evacuation for non-viable pregnancy.

BACKGROUND: Medications or mechanical dilators are often used to soften and dilate the cervix prior to surgical evacuation of the uterus for … rmacological or mechanical agents to ripen the cervix in women undergoing dilation and curettage or vacuum aspiration for non-viable pregnancy at less than 14 weeks' gestation were eligible for inclusion. Cluster-randomised controlled trials and trials using a cross-over design were not eligible for inclusion.Unpublished randomised controlled trials and …

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.

BACKGROUND: Newborn infants have the ability to experience pain. Newborns treated in neonatal intensive care units are exposed to numerous painful procedures. Healthy newborns are exposed to pain if the birth process consists of assisted vaginal birth by vacuum extraction or by forceps and during blood sampling for newborn screening tests. OBJECTIVES: Primary objectiveTo determine the efficacy and safety of paracetamol for the prevention or treatment of procedural/postoperative pain or pain associated with clinical conditions in neonates. Secondary objectiveTo review the effects of various do…

Улучшить долгосрочные механические свойства термопластических короткокалорийных соединений с использованием альтернативных матриц.

Древесные пластиковые композитные материалы (ВКН) обеспечивают средства для уменьшения углеродного следа за счет использования натуральных волокон для повышения механических свойств. Однако имеется ограниченная информация о механических свойствах этих материалов во враждебных условиях. В этом исследовании была проведена оценка составов полипропилена (PP), полистирола (PS) и полилактической кислоты (PLA), обработанных путем экструдирования и инъекции. Были проведены испытания на прочность и модулю прочности на растяжение и флексур, температуру смещения тепла (HDT) и на анализ ползучести при раз

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… The wood fibers were dried for 4 days at 105 °C in a ventilation oven (VWR Ventiline, Haryana, India), followed by 4 days under vacuum (Thermo Scientific Vacutherm, Waltham, MA, USA) at 105 °C. … The vacuum port was maintained at 0.7 bar relative negative pressure. The temperature settings for the various materials are presented in Table 2 . …

Complication Avoidance in Surgical Management of Vertebral Column Tumors.

The surgical management of spinal tumors has grown increasingly complex as treatment algorithms for both primary bone tumors of the spine and metastatic spinal disease have evolved in response to novel surgical techniques, rising complication rates, and additional data concerning adjunct therapies. In this review, we discuss actionable interventions for improved patient safety in the operative care for spinal tumors. Strategies for complication avoidance in the preoperative, intraoperative, and postoperative settings are discussed for approach-related morbidities, intraoperative hemorrhage, wo

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… The patient was discharged home with the wound vacuum, visiting nurse services, and a course of apixaban, and ultimately, she had a good functional outcome and resumed systematic therapy. … As observed in this case, patients with wound vacuums situated in the lumbopelvic region may be subject to prolonged bedrest and are at greater risk of VTE during their recovery. 5. …

Oral Presentations

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Autologous stem cell transplantation improves quality of life in economically challenged, Brazilian multiple myeloma patients.

OBJECTIVES: 1) To characterize the impact of multiple myeloma on the quality of life of patients treated in two public institutions in São Paulo State, Brazil, using a generic Short Form 36 Health Survey and a questionnaire specific for oncologic patients (QLQ-C30) upon diagnosis, after the clinical treatment, and at day +100 after autologous stem cell transplantation; 2) to evaluate whether autologous stem cell transplantation can improve the quality of life of our economically challenged population aside from providing a clinical benefit and disease control. METHODS: We evaluated 49 patient

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… This classification was created in 2000 and considers how many bathrooms, color TVs, radios, cars, vacuum cleaners, washing machines, DVD players, refrigerators, freezers and housemaids are in the patient's household. …

Оказываешь новую клиническую услугу - что у тебя в лифте?

Люди с множественным склерозом (PwMS) определяют эмоциональное благополучие как одну из ключевых неудовлетворенных потребностей в уходе. Меры, основанные на заботливости, могут повысить эмоциональное благосостояние в ПВМС; вместе с тем отсутствует информация о том, как они применяются в рамках обычного ухода. Лица, оказывающие влияние на политику в области здравоохранения, могут получить критическую информацию о процессе осуществления. Цель этого исследования заключалась в изучении потребностей и приоритетов тех, кто оказывает влияние на политику в области здравоохранения, в деле внедрения МБМ

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… This new initiative is … and everyone agrees that this would be a great initiative , but it gets lodged in the vacuum of everything else that is going on” – ID 010 “To me , it is becoming more and more clear how our system is disconnected , and I think because of that , a lot of our new programs … This new initiative is … and everyone agrees that this would be a great initiative , but it gets lodged in the vacuum of everything else that is going on” – ID 010 Another participant further noted that integration should be a key focus. “Integration is a big one. …

Cold Atmospheric Plasma in the Treatment of Osteosarcoma.

Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring most commonly in adolescents and young adults. Major improvements in disease-free survival have been achieved by implementing a combination therapy consisting of radical surgical resection of the tumor and systemic multi-agent chemotherapy. However, long-term survival remains poor, so novel targeted therapies to improve outcomes for patients with osteosarcoma remains an area of active research. This includes immunotherapy, photodynamic therapy, or treatment with nanoparticles. Cold atmospheric plasma (CAP), a hig

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… Depending on the plasma force, physical action is based on positive and negative ions, electrons, photons, and electromagnetic fields leading to the emission of visible ultraviolet (UV) or vacuum ultraviolet (VUV) radiation, and thermal effects. … Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids Phys. Plasmas 2015 22 122008 10.1063/1.4934989 86. Schneider S. Lackmann J.W. Narberhaus F. Bandow J.E. Denis B. Benedikt J. …

Harvest and Application of Bone Marrow Aspirate Concentrate to Address Acetabular Chondral Damage During Hip Arthroscopy.

BACKGROUND: During hip arthroscopy, managing concomitant cartilage damage and chondrolabral junction breakdown remains an ongoing challenge … gh the lateral cortex of the ilium just proximal to the sourcil. Under a relative negative-pressure vacuum, bone marrow is aspirated into 3 separate heparin-rinsed 50 mL syringes, each containing 5 mL of ACD-A. Slow and steady negative pressure should be used to pull back on the syringe plunger to aspirate a total volume of 40 mL into each syringe. To av …

Дело о фульминантном некротизирующем фасиите верхней конечности в иммунокомпрометированном пациенте.

Некротизирующий фаскиит (NF) — редкий, чрезвычайно агрессивный и угрожающий конечностям и жизни инфекция мягких тканей, требующая хирургического вмешательства. Диагноз часто задерживается неспециализированными ранними исследованиями, и иммунокомпромиссные пациенты подвергаются особому риску в связи с хладнокровными, атипичными представлениями. Мы представляем случай 70-летнего мужчины с отдаленной историей множественных миелом, обработанных трансплантацией стволовых клеток, который разработал большой NF правой верхней конечности в течение 24 часов после небольшой тупой травмы. Несмотря на появ

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… A wound vacuum-assisted closure (VAC) was attached to the amputation stump. The patient had minimal blood loss and was sent to the post-anesthesia care unit (PACU) in stable condition. Wound and blood cultures returned positive for Streptococcus pyogenes . …

Обобщение и оценка 6-ариламинобензамидов в качестве позитронных фотографических лигандов для рецептора фингозина-1-фосфата-5.

Спингосин-1-фосфат-5 (S1P5) является одним из пяти мембранных белковых рецепторов G, которые активируются лизофосфолипидом, фосфатом-1, что приводит к регулированию многих клеточных процессов. Рецепторы S1P5 расположены на олигодендроцитах и предлагаются для оказания влияния на физиологию олигодендроцитов. Понимание модуляции S1P5 в ходе таких процессов, как ремиелионация, может иметь потенциальные возможности для демиелионизации расстройств CNS, таких, как множественный склероз (MS). В этой связи мы сообщаем об обобщении и предварительной оценке серии фторированных 6-ариламинобензамидов в кач

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… The plate was filtered using a Millipore vacuum manifold, with a pressure between 600–800 mbar and then dried at 50 °C for 1–2 h. … This solution was dried by being stirred at 100 °C under vacuum and a stream of helium gas for 2 min. This process was repeated twice using acetonitrile (2 × 1 mL). The [ 18 F]fluoride was then completely dried by applying full vacuum for 1 min. …

Глубинные пространственные омики MLADI-MS, управляемые квантовой каскадной лазерной микроскопией среднего инфракрасного изображения.

В пространственной "omics " высокоуверенные молекулярные идентификации необходимы для исследования сложной биологии и для пространственной биомаркировки. Однако нынешняя масс-спектрометрическая съемка (MSI) на основе пространственной "омики" должна скомпрометировать скорость получения данных и глубину биохимического профилирования. Здесь мы введём быструю, без этикеток квантовую каскадную лазерную микроскопию среднего инфракрасного изображения (QCL-MIR), чтобы направить MSI в высокоинтересные области тканей, такие маленькие, как гломерули почки, культурные многоклеточные сфероидные я

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… Dried ITO slides were put in a slide mailer and vacuum-sealed to avoid environmental influences on the samples. … To tissue prevent degradation due to environmental conditions, the slides were either processed immediately or carefully placed in a slide mailer, vacuum-sealed and stored at −80 °C for optimal sample preservation. …

Staying Abreast of New Biomarkers in Hematology/Oncology.

There has been an increasing number of approvals for targeted therapies in oncology in the past decade, changing the treatment paradigm for many solid tumors and hematologic malignancies. At JADPRO Live 2023, presenters provided an in-depth review of cancer biomarkers, including testing methodology, recommended therapies, and how advanced practitioners can integrate results into clinical decision-making.

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… “It is interesting to understand that none of these mutations exist in a vacuum,” said Mr. Guinigundo. For example, a KRAS mutation with an STK11 mutation or a KRAS mutation with a KEAP1 mutation predicts a poor response to PD-L1 or PD-1 inhibitors. …

The Rates of Cement Leakage Following Vertebroplasty in Osteoporotic versus Metastatic Disease.

Introduction Percutaneous vertebroplasty is used for symptomatic osteoporotic fractures and osteolytic neoplasms. We performed a retrospective study to analyze the pattern of leaks in the two cohorts. Material and Methods Vertebroplasties performed over a 7-year period at a tertiary orthopaedic center were included in the study and divided into osteoporotic and neoplastic groups. The incidence and pattern of cement leaks in each group were documented and analyzed. Results There were 75 leaks of a cohort of 211 vertebroplasties with a relatively equal proportion in osteoporotic and neoplastic g

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… Pathogenesis of the intravertebral vacuum of Kümmell's disease. Exp Ther Med. 2016;12(02):879–882. doi: 10.3892/etm.2016.3369. 25. Chou L H, Knight R Q. Idiopathic avascular necrosis of a vertebral body. Case report and literature review. …

High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial.

BackgroundStereotactic body radiation therapy (SBRT)using intensity-modulated radiotherapy (IMRT) can be a safe modality for treating spinal bone metastasis with enhanced targeting accuracy and an effective method for achieving good tumor control and a rigorous pain response.Methods/designThis is a single-center, prospective randomized controlled trial to evaluate pain relief after RT and consists of two treatment groups with 30 patients in each group. One group will receive single-fraction intensity-modulated RT with 1 × 24 Gy, and the other will receive fractionated RT with 10 × 3 Gy. The ta

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… Immobilization is ensured with an Aquaplast head mask (Aquaplast Corporation, Wyckoff, NJ, USA), vacuum mattress, and Wingstep® (Elekta, Stockholm, Sweden). On the basis of the planning CT, risk organs and clinical target volume (CTV) are contoured. …

Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy.

Matrix metalloproteinases (MMPs) are a family of enzymes involved at different stages of cancer progression and metastasis. We previously identified a novel class of bisphosphonic inhibitors, selective for MMPs crucial for bone remodeling, such as MMP-2. Due to the increasing relevance of specific MMPs at various stages of tumor malignancy, we focused on improving potency towards certain isoforms. Here, we tackled MMP-9 because of its confirmed role in tumor invasion, metastasis, angiogenesis, and immuno-response, making it an ideal target for cancer therapy. Using a computational analysis, we

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… After a given time, the mixture was dried under vacuum and dissolved in EtOAc; the resulting solution was washed with NaHCO 3 and then with HCl 1N, NH 4 Cl ss, and brine. The organic phase was finally dried over anhydrous Na 2 SO 4 , filtered, and the filtrate was evaporated in vacuo. … The resulting solution was dried under vacuum. EtOAc was subsequently used to dilute the residue; then, 6-M NaOH was added until pH = 6. After separation of the layers, the organic phase was washed with brine, dried over anhydrous Na 2 SO 4 , filtered, and the filtrate was dried in vacuo. …

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour.

BACKGROUND: Epidural analgesia is often used for pain relief during labour and childbirth, and involves administration of local anaesthetics … ural-related adverse effects including caesarean delivery, instrumental delivery (use of forceps or vacuum devices), prolonged duration of labour analgesia, and LA consumption. However, clear evidence of the superiority of one technique over the other is lacking. Also, differences in the initiation of epidural analgesia such as combined spinal-epidural ( …

Comparison of vertebroplasty using directional versus straight needle.

BACKGROUND: Percutaneous vertebroplasty is a minimally invasive procedure that can be performed to treat pain and immobility associated with vertebral compression fractures. Previous studies have shown that a single injection can achieve adequate fill across the midline of the vertebral body. PURPOSE: To compare the radiological outcomes of using a novel steerable needle with using a conventional, straight needle in unipedicular vertebroplasty. MATERIAL AND METHODS: Data were collected from 19 patients who were operated at our institute between 1 September 2010 and 31 March 2011. Outcomes we

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… Am J Roentgenol 2009 ; 193 : 442 – 445 . 10.2214/AJR.09.2774 19843725 16 Peh WC Gelbart MS Gilula LA Percutaneous vertebroplasty: treatment of painful vertebral compression fractures with intraosseous vacuum phenomena . …

Continuation versus discontinuation of intravenous oxytocin in the active phase of labour.

RATIONALE: Intravenous oxytocin is widely used to induce labour or to augment labour (i.e. enhance contractions to promote progression), wit … cal outcome was caesarean section. Important maternal outcomes included instrumental vaginal birth (vacuum extraction or forceps delivery), postpartum haemorrhage, maternal infection, maternal satisfaction, duration of the active phase of labour, uterine hyperstimulation (tachysystole with abnormal CTG (cardiotocography)), and uterine tachysystole with n …