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Case Report: When pancreatic cancer is not cancer: a rare case of pancreatic head paraganglioma with life-threatening delayed pseudoaneurysm bleeding.

BACKGROUND: Primary pancreatic paragangliomas are extremely rare neuroendocrine tumors that may radiologically and cytologically mimic pancreatic ductal adenocarcinoma. Importantly, paragangliomas may be functional tumors capable of secreting catecholamines, which can lead to severe hypertensive crises during biopsy or surgical manipulation if unrecognized. CASE PRESENTATION: A 54-year-old male presented with intermittent abdominal pain. Cross-sectional imaging revealed a 13-mm mass in the pancreatic head. ERCP-guided duodenal brush cytology suggested malignant cells, and pancreaticoduodenect

Managing Nutrition After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC): A Qualitative Study of Colorectal Cancer Survivors' and Caregivers' Experiences.

BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is a potentially curative treatment for peritoneal metastasis in colorectal cancer. The procedure is extensive, and colorectal cancer survivors experience prolonged nutrition-impact symptoms and significant weight loss. OBJECTIVE: The aim of this study was to explore colorectal cancer survivors' and caregivers' experiences with managing nutrition after the CRS-HIPEC procedure. DESIGN: A qualitative descriptive design was used to gain insight into colorectal cancer survivors' and caregivers' experience

Coccygodynia in a Long-Term Cancer Survivor Diagnosed with Metastatic Cancer: A Case Report.

Background and Objectives: Rectal cancer is considered cured if no recurrence is found during the 5-year follow-up period after treatment. After this period, patients often believe that the cancer is completely eradicated. However, in modern society, where lifespans have become longer, it is important to recognize that metastatic cancer may occur long after the initial treatment has concluded. This highlights the necessity of continued vigilance and the long-term follow-up of cancer survivors. Case report: We present a case of metastatic cancer of the coccyx in an 87-year-old female patient. T

Factors associated with palliative care symptoms in cancer patients in Palestine.

Palliative care is critical to redundancy in cancer patients seeking to improve their quality of life. Evaluation should be incorporated into clinical practice routines at all stages of cancer. The Edmonton Symptom Assessment System (ESAS) was used to rate the intensity of ten symptom evaluations designed and validated for cancer patients in various languages and cultures. Therefore, the study aims to assess the symptoms reported using ESAS scores to identify patients who would benefit from palliative care that can improve the integration of palliative care into standard cancer care at An-Naja

The effect of Benson relaxation technique on cancer patients: a systematic review.

PURPOSE: Although many studies have investigated the effect of this method on cancer patients, no review of the available literature has been done. So, a literature review is conducted to evaluate all published literature on the Benson relaxation technique in cancer patients. METHODS: A systematic literature search was conducted. A systematic search of online electronic databases including PubMed/MEDLINE, Scopus Web of Science, PsycINFO, and EMBASE was performed using keywords extracted from Medical Subject Headings such as "Benson Relaxation Technique," "Cancer Patients," "Malignancy," and "

Quality of life and its influencing factors among breast cancer patients at Tikur Anbessa specialised hospital, Addis Ababa, Ethiopia.

BACKGROUND: Quality of life (QoL) has become an important measure for evaluating cancer patients' treatment and prognosis. Breast cancer patients are at an increased risk of experiencing poor QoL during active treatment of cancer. This study aimed to assess QoL and it's influencing factors among breast cancer patients using the newly updated breast cancer specific tool of the European Organisation for Research and Treatment of Cancer EORTC Breast Cancer Specific Quality of Life Questionnaire QLQ-BR45. METHODS: An institutional based crossectional study was conducted with 248 breast cancer pat

Cancer patient perspectives on survivorship goals from the Smart Patients online community.

BackgroundCancer impacts individuals' life goals. Recent cancer care guidelines recommend discussing life goals as part of patient-provider communication. The goal of this study was to understand patients' attitudes toward goal sharing with their cancer care providers.Patients and methodsSemi-structured questionnaires were conducted via email with cancer patients and survivors (n = 39) on an online social network called Smart Patients. Participants answered open-ended questions about their life goals. They then completed a survey regarding their attitudes toward goal sharing with healthcare pr

Comparison of quality of life and worry of cancer recurrence between endoscopic and surgical treatment for early gastric cancer.

BACKGROUND: The quality of life (QOL) of patients who survive early gastric cancer (EGC) is an area of increasing interest. OBJECTIVE: To compare the QOL and degree of worry of cancer recurrence in EGC patients who underwent endoscopic submucosal dissection (ESD) or surgery. DESIGN: Cross-sectional study. SETTINGS: A tertiary referral center. PATIENTS: A total of 565 patients with EGC who received ESD or surgery. INTERVENTION: Questionnaires. MAIN OUTCOME MEASUREMENTS: QOL was evaluated using the Short-form Health Survey and the European Organization for Research and Treatment of Cancer

Integration of palliative care in a multidisciplinary head and neck cancer clinic: A prospective cohort study.

BACKGROUND: Integrated palliative care may improve outcomes in patients with cancer, but few studies have specifically evaluated its benefits in head and neck cancer. AIM: To assess changes in symptom control, quality of life, and supportive care needs in patients with head and neck cancer consecutively treated at a palliative care outpatient clinic over 12 months. DESIGN: Prospective cohort study. Symptoms were assessed at baseline and at 1.5, 3, 6, 9, and 12 months, and quality of life at baseline, 2, and 4 months. Symptom management was adjusted and referrals made as needed. SETTING AND

Quality of life and perceived care in Lynch syndrome: Associated factors and interpretable machine-learning classification.

PURPOSE: To examine associations between pathogenic variant carrier status, cancer status, health-related quality of life (QoL), and perceived quality of care in Lynch syndrome, and to inform oncology nursing supportive care. METHODS: This cross-sectional study included 288 adults with Lynch syndrome carrying a pathogenic germline variant, with or without a history of cancer, and non-carrier relatives. Clinical and demographic data were extracted from medical records. QoL and perceived quality of care were assessed using validated instruments. Analyses included descriptive and inferential sta

Symptom burden and quality of life in patients with pancreatic and peri-pancreatic cancer at admission to specialized palliative care: a nationwide register-based study in Denmark.

BACKGROUND: Most patients with pancreatic cancer have advanced disease at the time of diagnosis and a poor prognosis. Therefore, it is important to investigate the symptom burden for these patients, e.g., at the start of specialized palliative care (SPC). AIM: To investigate symptoms, problems, and quality of life in patients with pancreatic cancer at the start of SPC and to explore the associations with demographic factors. METHOD: The data sources were the national Danish Palliative Care Database and Danish Pancreatic Cancer Database. Patients with pancreatic and peri-pancreatic cancer, wh

Exercise Therapy in Oncology—the Impact on Quality of Life and Side Effects.

BACKGROUND: The diagnosis and treatment of cancer are highly stressful. Exercise therapy is often used to mitigate the adverse effects of treatment. But how good is the evidence base, and what has changed in recent years? In this narrative review, we present the current data and what it implies for the care of adults with cancer. METHODS: This review is based on data from meta-analyses and systematic reviews concerning 16 relevant clinical endpoints (outcomes) of exercise therapy for cancer patients. RESULTS: The literature evaluated for this paper reveals that targeted exercise therapy is f

Metastatic spread of primary lung adenocarcinoma to the small intestine: A case report.

INTRODUCTION AND IMPORTANCE: Metastasis of primary lung cancer to the small intestine is rare, and the prognosis is poor. Early diagnosis of small intestinal metastasis is difficult because the incidence of clinically obvious symptoms is low. CASE PRESENTATION: This report described a rare case of small intestine metastasis of lung adenocarcinoma. It is worth noting that the patient was diagnosed with lung adenocarcinoma (T2aN0M0, stage IB) over a year ago. However, he complained of fever, black stools, and abdominal pain for about a year after the surgery. Enhanced CT scans showed thickening

Diagnostic delay of gynaecological cancer in women with postmenopausal bleeding.

INTRODUCTION: Postmenopausal bleeding is the primary reason for referral to the gynaecological fast-track suspected cancer programme due to an elevated risk of endometrial cancer. The aim of this study was to examine the diagnostic flow among women with postmenopausal bleeding. METHODS: Data were collected and analysed from 362 women at Sygehus Sønderjylland referred with the International Classification of Diseases, tenth edition, diagnosis "DN950 postmenopausal bleeding" from 2015 to 2019. RESULTS: We found a mean 83-day period between the initial consultation and the final cancer diagnosi

The quality, suitability, content and readability of online health-related information regarding sexual dysfunction after rectal cancer surgery.

AIM: Patients are not well informed about sexual dysfunction after rectal cancer surgery and often turn to the Internet for information. The purpose of this study was to assess online information for patients on sexual dysfunction after rectal cancer surgery. METHODS: An online search of Google, Yahoo and Bing was performed using specific (e.g., rectal cancer surgery and vaginal pain) and general (e.g., rectal cancer surgery and sex) search terms. Inclusion criteria were websites in English, designed for patients, and including content regarding sexual dysfunction after rectal cancer surgery.

Trends in End-of-Life Resource Utilization and Costs among Prostate Cancer Patients from 2006 to 2015: A Nationwide Population-Based Study.

PURPOSE: The purpose of this study was to evaluate end-of-life resource utilization and costs for prostate cancer patients during the last year of life in Korea. MATERIALS AND METHODS: The study used the National Health Information Database (NHIS-2017-4-031) of the Korean National Health Insurance Service. Healthcare claim data for the years 2002 through 2015 were collected from the Korean National Health Insurance System. Among 83,173 prostate cancer patients, we enrolled 18,419 after excluding 1,082 who never claimed for the last year of life. RESULTS: From 2006 to 2015, there was a 3.2-fo

Thromboembolism after cardiac surgery in a patient with cancer-related thrombosis and severe thrombocytopenia: A case report.

RATIONALE: Patients with cancer have elevated risk of both venous thromboembolism and bleeding compared with patients without cancer due to cancer- and patient-specific factors. Balancing the increased and competing risks of clotting and bleeding in these patients can be difficult because management of cancer-associated thrombosis requires anticoagulation despite its known increased risks for bleeding. The adjustment of blood transfusion or cessation of anticoagulants can be a challenge in surgical diagnosis or treatment of cancer patients with such an imbalanced coagulate status. PATIENT CON

The efficacy and safety of electro-acupuncture for alleviating chemotherapy-induced peripheral neuropathy in patients with coloreactal cancer: study protocol for a single-blinded, randomized sham-controlled trial.

BackgroundColorectal cancer is the most common cancer in Hong Kong. Oxaliplatin-based chemotherapy is a major first-line conventional therapy for advanced and metastatic colorectal cancer. However, oxaliplatin causes chemotherapy-induced peripheral neuropathy (CIPN). Acupuncture has long been used to alleviate limb numbness in Chinese medicine. This study aims to examine the efficacy and safety of acupuncture for alleviating CIPN in patients with colorectal cancer in Hong Kong.Methods/designThis is a single-blinded, randomized, sham-controlled efficacy trial. Eighty-four eligible patients, who

Insights into platinum-induced peripheral neuropathy-current perspective.

Cancer is a global health problem that is often successfully addressed by therapy, with cancer survivors increasing in numbers and living longer world around. Although new cancer treatment options are continuously explored, platinum based chemotherapy agents remain in use due to their efficiency and availability. Unfortunately, all cancer therapies affect normal tissues as well as cancer, and more than 40 specific side effects of platinum based drugs documented so far decrease the quality of life of cancer survivors. Chemotherapy-induced peripheral neuropathy is a frequent side effects of plat

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… Generally, cancer pain includes mixed mechanisms and rarely presents as a purely neuropathic pain, but rather as a complex with inflammatory and/or ischemic components. Accordingly, a distinction between cancer and noncancer-related neuropathic pain is almost impossible. … AAPT diagnostic criteria for chronic cancer pain conditions. J Pain. 2017;18:233–246. doi: 10.1016/j.jpain.2016.10.020. 64. Palm-Espling ME, Andersson CD, Bjorn E, Linusson A, Wittung-Stafshede P. …

[Clinical characteristics of metastasis-induced acute pancreatitis in patients with lung cancer].

Objective: To analyze the clinical features and prognosis of lung cancer patients with metastasis-induced acute pancreatitis (MIAP), and to provide clues for early diagnosis. Methods: The characteristics and prognosis of 8 patients with MIAP in lung cancer admitted to Peking Union Medical College Hospital from January 2002 to September 2019 were retrospectively analyzed and were compared with non-tumor-induced AP. Results: Sevencases(7/8) were Mild AP, one (1/8) was Severe AP. Four patients (4/8) presented with AP as the reporting sign and lung cancer was not diagnosed until (112±36) days afte