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An Appraisal of the Oleocanthal-Rich Extra Virgin Olive Oil (EVOO) and Its Potential Anticancer and Neuroprotective Properties.

Dietary consumption of olive oil represents a key pillar of the Mediterranean diet, which has been shown to exert beneficial effects on human health, such as the prevention of chronic non-communicable diseases like cancers and neurodegenerative diseases, among others. These health benefits are partly mediated by the high-quality extra virgin olive oil (EVOO), which is produced mostly in Mediterranean countries and is directly made from olives, the fruit of the olive tree (Olea europaea L.). Preclinical evidence supports the existence of antioxidant and anti-inflammatory properties exerted by t

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… The PDO label is an EU quality certification that protects foods, agricultural products and wines made within specific geographical areas, under specific physical and biological conditions, and using well-defined production practices [ 11 ]. 2. … Later in the text, we will also provide the example of a typical quality certification of an Italian nutraceutical EVOO, with laboratory results regarding the concentrations of distinct polyphenols. …

Psychiatric disorders in adolescent and young adult cancer survivors in Korea.

BackgroundAlthough adolescent and young adult (AYA) cancer survivors have an increased risk of psychiatric disorders, limited evidence has been suggested. We aimed to determine the risk of psychiatric disorders among AYA cancer survivors.Materials and methodsA retrospective population-based cohort study based on the Korea National Health Insurance Service database was carried out. All men and women aged 15-39 years diagnosed with cancer between 2006 and 2019 (N = 88 965) were included and matched with controls (1 : 4). The prevalence ratios (PRs) of psychiatric disorders were calculated in can

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… a self-administered questionnaire on medical history and health behavior, including smoking, drinking and physical activity, anthropometric measurements, and laboratory tests. 18 The participation rate among the target population was ∼76%. 18 Vital status and cause of death were obtained from death certification … As enrollment in this program is indicated by a special copayment reduction code for cancer (V193) and requires a medical certificate from a physician, the cancer diagnoses included in this study are considered sufficiently reliable, and this method has been used in previous studies. 20 Study outcomes …

Psychological distress, chronic conditions and quality of life in elderly hematologic cancer patients: study protocol of a prospective study.

BackgroundSimilar to most solid tumors, the incidence of hematologic malignancies has been rising. Although the median age at diagnosis is about 70 years, little is known about psychosocial aspects and comorbid conditions in elderly patients with hematologic cancers. The main objectives of our study are to assess the prevalence of psychological distress, chronic conditions, functional disabilities, and quality of life in both elderly hematologic cancer patients aged ≥70 years and an age-matched comparison sample of the general population.MethodsWe conduct a prospective study with three measuri

Predictive value of serial measurements of quality of life on all-cause mortality in prostate cancer patients: data from CaPSURE (cancer of the prostate strategic urologic research endeavor) database.

IntroductionHealth-related quality of life (HRQOL) is a legitimate construct for evaluating treatment and its side effects. Recently, predictive value of HRQOL on survival also has been of interest. In light of the longer survival in patients with prostate cancer and importance of quality of life, we seek to evaluate the association between HRQOL and survival using traditional and novel techniques.MethodsPatients from CaPSURE (Cancer of the Prostate Strategic Urologic Research Endeavor) who were treated within 6 months of diagnosis and had pre-treatment and sufficient post-treatment follow-up

Surveillance for Violent Deaths - National Violent Death Reporting System, 50 States, the District of Columbia, and Puerto Rico, 2023.

PROBLEM/CONDITION: In 2023, approximately 23,000 persons died of homicide and 49,000 persons died of suicide in the United States, according to the National Vital Statistics System. This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) on violent deaths and suicides that occurred in the 50 states, the District of Columbia, and Puerto Rico in 2023. PERIOD COVERED: 2023. DESCRIPTION OF SYSTEM: NVDRS collects data from death certificates, coroner and medical examiner records, and law enforcement reports. This report includes data collected from all 50 states, th

Surveillance for Violent Deaths - National Violent Death Reporting System, 42 States, the District of Columbia, and Puerto Rico, 2019.

PROBLEM/CONDITION: In 2019, approximately 67,000 persons died of violence-related injuries in the United States. This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) on violent deaths that occurred in 42 states, the District of Columbia, and Puerto Rico in 2019. Results are reported by sex, age group, race and ethnicity, method of injury, type of location where the injury occurred, circumstances of injury, and other selected characteristics. PERIOD COVERED: 2019. DESCRIPTION OF SYSTEM: NVDRS collects data regarding violent deaths obtained from death certific

Twenty five years of the National Academy of Medical Sciences of Ukraine - progress and priorities for future of radiation medicine and biology.

After the creation of the Academy of Medical Sciences of Ukraine in 1993 the Research Center for Radiation Medicine was among the first institutions to join the Academy (fig. 1). Estab lishing the Academy was among the first steps of the independent Ukrainian government and aimed to provide a high level health care for population. It was extremely needed for the minimization of Chornobyl medical consequences. This choice was related to a growing recognition of the scientific research in fulfilling the Сenter's mission - study of the effects of low dose radiation on human body and radiation pro

Patient Perceptions of CAR-T Therapy in the USA: Findings from In-Depth Interviews.

INTRODUCTION: Chimeric antigen receptor-T cell (CAR-T) therapy has revolutionized advanced blood cancer treatment. However, preparation, administration, and recovery from these therapies can be complex and burdensome to patients and their care partners. Utilization of an outpatient setting for CAR-T therapy administration could help improve convenience and quality of life. METHODS: In-depth qualitative interviews were conducted with 18 patients in the USA with relapsed/refractory multiple myeloma or relapsed/refractory diffuse large B-cell lymphoma, 10 of whom had completed investigational or

Physical Activity in People with Multiple Myeloma: Associated Factors and Exercise Program Preferences.

People with multiple myeloma (MM) often experience disease symptoms and treatment toxicities that can be alleviated through physical activity (PA). However, the majority of people with MM are insufficiently active. This study explored PA among people with MM, including differences by treatment stage, symptoms and demographics, and programming preferences. Overall, 126 people with MM (77% response rate) completed the survey. Pre-diagnosis, 25.4% were sufficiently active, with 12.0% remaining active after treatment. Respondents who were physically active pre-diagnosis were 46.7 times (95% confid

Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions.

Nuclear receptors (NRs) are a large family of ligand-dependent transcription factors that regulate the expression of a wide range of target genes in response to endogenous and exogenous ligands, including steroid hormones, thyroid hormone, vitamin D, retinoic acid, fatty acids, and oxidative steroids. Upon ligand binding, nuclear receptors form dimer complexes with transcriptional cofactors, which interact with specific DNA sequences in the promoter or enhancer regions of target genes to modulate gene expression. This process plays a crucial role in many physiological processes such as reprodu

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… This may be because the study is not done, the deadline for submitting results has not passed, this study is not required to submit results, or the sponsor or investigator has requested or received a certification to delay submitting the results) NAFLD BAR502; Placebo PHASE1 NCT03469583 COMPLETED (No … This may be because the study is not done, the deadline for submitting results has not passed, this study is not required to submit results, or the sponsor or investigator has requested or received a certification to delay submitting the results) Ulcerative Colitis; Inflammatory Bowel Disease Vitamin …

Real-World Quantitative Insights into the Treatment Experience of Patients with Cancer in the USA with Subcutaneous Versus Intravenous Drug Delivery.

IntroductionWhile oncology treatments have traditionally been delivered through the intravenous (IV) route of administration (ROA), subcutaneous (SC) alternatives have become increasingly available. Research comparing real-world patient experiences with these ROAs in the USA has been limited. This study aimed to quantify and compare preferences, satisfaction, and daily life impact between SC and IV delivery for patients with cancer in the USA experienced with both ROAs in a real-world setting.MethodsPatients with cancer in the USA experienced with both SC and IV delivery were eligible to compl

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… Most respondents had a college or university degree (36.3%) or had completed either some college or a certification program (32.3%). Approximately half of respondents had private health insurance, 25.9% had Medicare, and 19.9% had Medicaid. … Highest degree of education completed | | Elementary/primary school | 5.5 | 11 Secondary/high school or general equivalency diploma (GED) | 17.9 | 36 Some college or certification program | 32.3 | 65 College or university degree | 36.3 | 73 Graduate/post-graduate degree | 8.0 | 16 Q45. …

Exercise Recommendation for People With Bone Metastases: Expert Consensus for Health Care Providers and Exercise Professionals.

PurposeExercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal complications. The International Bone Metastases Exercise Working Group (IBMEWG) was formed to develop best practice recommendations for exercise programming for people with bone metastases on the basis of published research, clinical experience, and expert opinion.MethodsThe IBMEWG undertook sequential steps to inform the recommendations: (1) modified

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… American Physical Therapy Association: Specialist certification in oncology from the American Physical Therapy Association, https://specialization.apta.org/become-a-specialist/oncology 36. … Thrive Health: Cancer & exercise training for health & fitness professionals by Thrive, https://thrivehealthservices.com/professionals/certification/ 40. EX-MED Cancer: EX-MED Cancer professional development, https://exmedcancerpd.learnbook.com.au/ 41. …

Эффект здоровой вакцины при оценке обновленного COVID-19 вакцины для пожилых людей.

Установленные факторы, определяющие состояние здоровья пожилых людей, помогают определять рутинные процедуры управления указанными вакцинами, в то время как неизмеримая слабость может ограничивать доступ к вакцинам. Мы оцениваем эффективность работы 2024-2025 COVID-19 вакцина адаптирована к Omicron JN.1 в шведском населении в возрасте ≥65 годы (N = 245 696). Эффективность вакцин (VE) COVID-19-related В период с октября в различных группах проводится оценка госпитализации и негативных результатов контроля (НКО; смертность от всех причин) 1, 2024 по март 31, 2025. В.Е. 75% (В тыс.95% CI 70%-79%)

Trends and Disparities in Cancer-Related Mortality Among Adults With Diabetes in the United States: 1999-2019.

AimCancer and diabetes are major public health concerns, with diabetes linked to increased cancer-related mortality. However, national trends and disparities remain underexplored.MethodsUsing CDC WONDER data, we analysed deaths where both diabetes and cancer were listed as causes. Age-adjusted mortality rates (AAMRs) were calculated for diabetic cancer patients aged ≥ 25 years and stratified by demographics and geography. Joinpoint regression estimated annual percent changes (APCs) and average annual percent changes (AAPCs).ResultsFrom 1999 to 2019, 699,007 cancer-related deaths occurred among

A web-based knowledge database to provide evidence-based information to cancer patients: Utilization within the PIKKO study.

PurposeCancer is associated with an urgent need for understandable and reliable information, which is often not satisfied by information available online. Therefore, as part of the PIKKO project, a web-based knowledge database (WDB) was introduced to provide cancer patients with quality-assured, evidence-based information. This paper aims to provide insights into the usage (Who? How? What?) and the effects regarding health literacy of the WDB.MethodsA patient survey and automatically generated logfile data were evaluated. Two user groups, patients and patient navigators (PNs), were compared.Re

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… Team HON (2020) HONcode certification: Key points of the certification. https://en.wikipedia.org/wiki/Health_On_the_Net_Foundation . Accessed 15 July 2024 19. …

The State of Obesity in Kansas: A Community Based Approach to Chronic Care Management.

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… physician relative value units for performance, and a paucity of clear guidelines to document an encounter for reimbursement. 21 , 22 , 33 , 34 A recent study investigating medical licensing examinations found that concepts deemed important for obesity prevention and treatment were not featured on certification … Dec 1, 2013. https://www.cdrnet.org/certifications/number-of-registered-dietitians-by-state . 60. Wing RR. Behavioral approaches to the treatment of obesity. In: Bray GA, Bouchard C, editors. Handbook of Obesity: Clinical Applications. 2nd Edition. New York: Marcel Dekker, Inc; 2004. 61. …

Lipid Level, Lipid Variability, and Risk of Multiple Myeloma: A Nationwide Population-Based Study of 3,527,776 Subjects.

(1) Background: There is evidence that abnormality in lipid metabolism promotes cancer development. This study investigated whether lipid level and its variability are associated with the development of MM at a population level. (2) Methods: A retrospective cohort study included a total of 3,527,776 subjects aged 40 and above who participated in ≥3 health examinations within the previous five years, including the index year (2012-2013). Total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) were measured, and visi

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… This application requires a medical certificate issued by a treating physician, and most people apply for it to reduce the out-of-pocket cost. This information was used to verify the cancer diagnosis in studies using the NHIS database [ 32 ]. … However, there is a certification process for quality control implemented by the NHIS and a large sample size would mitigate such an effect. Third, our study only included a South Korean population. …

Pathology Competencies in Medical Education and Educational Cases: Update 2023.

Pathology is a core component of medical school curricula because understanding the pathogenesis of the disease is foundational both for diagnostic efficiency and optimal use of ancillary resources in patient care. The Pathology Competencies for Medical Education (PCME) were developed as a national resource of expectations of pathology knowledge for medical students. The PCME are composed of three competencies: disease mechanisms and processes, organ system pathology, and diagnostic pathology and therapeutic pathology. The learning goals and learning objectives of the PCME that were first publ

International Congress on Academic Medicine: 2025 medical education abstracts.

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… The conference earned a Gold Level certification of sustainability from Dalhousie's Sustainability Office, recognizing its dedication to sustainable event planning practices. …

Application of wearables for remote monitoring of oncology patients: A scoping review.

ObjectiveThis review aims to systematically map and categorize the current state of wearable applications among oncology patients and to identify determinants impeding clinical implementation.MethodsA Medline, Embase and clinicaltrials.gov search identified journal articles, conference abstracts, letters, reports, dissertations and registered studies on the use of wearables in patients with malignancies published up to 10 November 2021.ResultsOf 2509 records identified, 112 met the eligibility criteria. Of these, 9.8% (11/112) were RCTs and 47.3% (53/112) of publications were observational. We

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… A high share of studies published by US-based authors was observed in line with other reviews. 62 , 70 Strict regulatory laws concerning medical certification in the EU were presumed as a cause. 70 This assumption can only be agreed with regarding prospective medical certification since this review found … a high share of studies that applied consumer-grade devices without medical certification—both in the EU and the USA. …