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Examining Correlates of Child Abuse with Adult Attachment and Sexual Satisfaction Among Adults.

Millions of children around the globe experience abuse every year, with over a thousand children dying within the United States in 2020 alon … chment as the mediator in a sample of 30,507 partnered adults from a cohort study. Results from the mediation analysis illustrated significant, albeit modest in size, negative links between childhood physical abuse and adult sexual satisfaction through levels of adult attachment insecurity. These results are important as they encourage clinicians to consider the ind …

Understanding Adult Attitudes Toward Corporal Punishment in Honduras: The Role of Sex, Gender Roles, Education, Childhood Experiences, and Psychopathy.

Corporal punishment (CP) remains a contentious issue in child-rearing debates, with varying opinions influenced by cultural, educational, an … legalizing parental use of force. However, a minority still considers spanking effective (24.66%). Mediation analysis shows that childhood psychological abuse significantly reduces support for CP, while psychopathy and stereotypical gender roles increase it. Females exhibit lower levels of psychopathy and adherence to traditional gender roles, which mediates their …

Associations of Paternal Seminal Plasma Metals with their Spouses' Unexplained Recurrent Spontaneous Abortion (URSA) Risk and the Potential Mediating Role of Oxidative Stress.

Unexplained recurrent spontaneous abortion (URSA) is a prevalent reproductive issue but its etiology remains obscure. Male exposure to envir … metal mixtures elevating URSA risk. MDA was significantly and positively associated with URSA risk. Mediation analysis shows that the associations of Ti, Cd or Mg with URSA risk appear to be mediated by MDA at rates of 23.30%, 16.26% or 34.48%, respectively. In vitro experiments confirmed the seminal plasma relevant dose Ti, Cd or Mg exposure induced male mouse sper …

Causal Association Between Chronic Inflammatory Arthropathies and Sarcopenia and the Mediation Role of Inflammatory Factors.

BACKGROUND: Although chronic inflammatory arthropathies (CIA) are associated with sarcopenia, sarcopenia plays a role in their pathogenesis remains unknown. This study investigated the causal relationship between sarcopenia and CIA and to identify potential mediating factors. METHODS: We examined data from 458 910 participants in the UK Biobank to analyze the association between sarcopenia-related traits and CIA. Associations between hand-grip strength, muscle mass, walking pace, and CIA were analyzed using Cox regression models. Then, we performed a mediation analysis to explore the underlyi…

Relationship Between Sarcopenia and the Trajectories of Depressive Symptoms Among Chinese Older Adults: The Mediating Effect of Social Participation.

BACKGROUND: This study evaluated the relationship between sarcopenia and the trajectories of depressive symptoms among Chinese older adults … l logistic regression. The potential mediating effect of social participation was evaluated through mediation analysis. Subgroup and interaction analyses were also carried out. RESULTS: The results showed that the depressive symptom score trajectory of the sarcopenia group was higher than that of the normal group. The depressive symptoms of the general participants …

Peripheral blood metabolic profiles of chronic rhinosinusitis and their mediating role between obesity and disease.

BACKGROUND: Chronic rhinosinusitis (CRS) is increasingly linked to systemic inflammation, however, research on peripheral blood metabolic pa … were compared across different CRS endotypes and between CRS patients and healthy controls. Causal mediation analysis assessed the mediating effects of metabolites on the relationship between body mass index and CRS. RESULTS: CRS patients exhibited distinct metabolic profiles, with dysregulated lipid metabolism characterized by increased triglycerides, free fatty …

Nonsuicidal self-injury (NSSI) amongst LGBT+ young adults: The role of psychological distress.

Rates of nonsuicidal self-injury (NSSI) among lesbian, gay, bisexual, transgender, and other sexual or gender minority (LGBTQ+) young adults are high. Research is needed to elucidate potential mechanisms underpinning this elevated risk. In 2021, young adults in the United Kingdom and United States (n = 1475, aged 18-30) reported their NSSI history and psychological distress (Kessler Psychological Distress Scale) in an online survey. Participants were cisgender heterosexual (CH; n = 1100), cisgender sexual minority (CSM; lesbian, gay, bisexual, asexual) (n = 272), or gender minority (GM; transg

Knowledge, attitudes, and practices (KAP) of the Philippine general public towards human mpox (hMPX): a cross-sectional study.

INTRODUCTION: In the Philippines, research on knowledge, attitudes, and practices (KAP) regarding human mpox (hMPX) remains limited, despite rising case numbers. With vaccines unavailable locally, enhancing community awareness and promoting non-pharmaceutical interventions are crucial for reducing transmission risks. METHODS: This cross-sectional study utilized an anonymized online data collection tool to explore the general public's hMPX KAP and their relationships, and identify sociodemographic groups linked to low hMPX knowledge; 502 respondents were included in the analysis. RESULTS: Kno

The mediating effect of individual beliefs between self-testing knowledge and HIV self-testing use.

Background: HIV self-testing has been introduced as a secondary mode of testing in most countries as a way of counteracting the barriers ass … using a structured, validated, self-administered questionnaire. Data were analysed using regression mediation analysis in Process Macro Model 4 in SPSS v27.Results: Perceived susceptibility (β = 0.06, Boot 95% [0.03, 0.10]) and benefits (β = 0.06, Boot 95% [0.24, 0.39]) mediated HIV self-testing knowledge and HIV self-testing use. Perceived barriers (β = 0.01, Boot …

Resilience, and Personality Traits as Independent Correlates of Perceived Treatment Management Abilities in Middle-Aged and Older People Living with HIV.

As people living with HIV (PLWH) age, they face various stressors that may negatively affect HIV treatment adherence and management. Resilie … 2 = 0.40), and this model retained resilience, openness, depression, and health literacy. Follow up mediation analysis found that resilience partially mediated the association between openness and treatment management ability. Resilience, openness, depression, and health literacy are important psychosocial factors related to treatment management ability. Interventio …

Боязнь рецидива в множестве склерозов: изучение роли совершенства и нетерпимости к неопределенности.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Повторные выбросы MS (RRMS) характеризуются значительной неопределенностью в силу непредсказуемого характера нападений и их переменного воздействия на функциональность. Такая неопределенность усиливает страх пациентов перед нападениями, что, в свою очередь, отрицательно сказывается на их благополучии и качестве жизни. Однако основополагающие механизмы, лежащие в основе этого страха, по-прежнему недостаточно понятны. Цель настоящего исследования заключалась в изучении взаимосвязи между страхом рецидива, совершенством и нетерпимостью в отношении неопределенности у отдельны

Совпадение в аннотации оригинала
BACKGROUND: Relapsing-remitting MS (RRMS) is characterized by considerable uncertainty due to the unpredictable nature of attacks and their … ). Intolerance of uncertainty was also positively related to fear of relapse (β = 0.37, p < 0.001). Mediation analysis further revealed that intolerance of uncertainty significantly mediated the relationship between perfectionism and fear of relapse, accounting for approximately 48% of the total effect (indirect effect β = 0.19, 95% CI [0.11, 0.26]). CONCLUSION: Th …

Moral injury, race-related stress and post-traumatic stress disorder in a trauma-exposed Black population.

BACKGROUND: Race-related stress (RRS) is an unrecognized source of moral injury (MI)-or the emotional and/or spiritual suffering that may em … ng civilian MIE and MID, RRS, and PTSD. Bivariate correlations were conducted with MIE and MID, and mediation analysis with MID, to examine the role of MI in the relationship between RRS and PTSD symptom severity. RESULTS: MIE was significantly correlated with cultural (r = 0.27), individual (r = 0.29), and institutional (r = 0.25) RRS; MID also correlated with cul …

Stress and Psychosocial Distress Scale with Blunted Oscillatory Dynamics Serving Abstract Reasoning.

BACKGROUND: Chronic stress is associated with a multitude of psychopathological disorders that share similar alterations in neural dynamics and symptomatology. Applying the National Institute of Mental Health's Research Domain Criteria (RDoC) framework, we probed the stress-diathesis model by identifying how a transdiagnostic psychosocial distress index representing high-dimensional patterns of stress-related aberrations was coupled to the neural oscillatory dynamics serving abstract reasoning. METHODS: The sample consisted of 69 adults (mean age = 44.77 years, SD = 13.66) who completed the N

Depressive disorder benefits of cities: Evidence from the China.

BACKGROUND: Rapid urbanization is a major trend in global population migration. There is growing debate about whether this urban-rural disparity exacerbate depression at the individual level. This study aims to investigate how urban living has a beneficial impact on individual mental health. METHODS: Based on the data of 15,764 participants in the 2018 China Health and Retirement Longitudinal Study (CHARLS), we perform analysis of variance to identify the gap in depression levels between urban and rural areas. Extensive comparisons and detailed statistical analyses are carried out to demonstr

Validation of the Chinese version of the vaccine conspiracy beliefs scale during COVID-19 pandemic and its correlates.

OBJECTIVE: To validate the Chinese version of the vaccine conspiracy beliefs scale (VCBS) and to investigate and compare its correlates among healthcare workers and non-healthcare workers during COVID-19 pandemic. METHODS: From March 19 to April 05, 2021, a nationwide cross-sectional online survey was administered to Chinese individuals aged 16 and above. The study aimed to assess the reliability and validity of the Chinese version of the VCBS. A binary logistic or linear regression model, along with mediation analysis, was employed to explore the relationship between vaccine conspiracy belie…

Mortality Benefits of Cardiac Rehabilitation in Coronary Artery Disease Are Mediated by Comprehensive Risk Factor Modification: A Retrospective Cohort Study.

BACKGROUND: Cardiac rehabilitation (CR) is a multicomponent intervention to reduce adverse outcomes from coronary artery disease, but its mechanisms are not fully understood. The aims of this study were to examine the impact of CR on survival and cardiovascular risk factors, and to determine potential mediators between CR attendance and reduced mortality. METHODS AND RESULTS: A retrospective mediation analysis was conducted among 11 196 patients referred to a 12-week CR program following an acute coronary syndrome event between 2009 and 2019. A panel of cardiovascular risk factors was assesse…

Hypertensive disorders of pregnancy, neonatal outcomes and offspring developmental delay in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.

INTRODUCTION: Developmental delay at an early age indicates the probability of continued problems after school age. Hypertensive disorders o … ed developmental delay in five areas. We performed multivariate quasi-Poisson regression and causal mediation analysis by neonatal outcomes. RESULTS: At 24 months of age, compared to offspring born from normotensive mothers, offspring born from HDP-affected mothers were more likely to experience developmental delay (risk ratio [RR] 1.29, 95% confidence interval [CI …

Association between childhood maltreatment and suicidal ideation among Chinese patients with chronic schizophrenia: the mediating role of insomnia.

BACKGROUND: Childhood maltreatment is a well-established transdiagnostic risk factor for suicidal ideation; however, previous studies on the … stionnaire - Short Form and Beck Suicidal Ideation Inventory were employed. Logistic regression and mediation analysis were performed. RESULTS: (a) The prevalence of suicide ideation, insomnia, sexual abuse, emotional neglect, emotional abuse, physical abuse and physical neglect was 10% (n = 61), 18% (n = 111), 11% (n = 68), 25% (n = 153), 6.3% (n = 39), 17% (n = 1 …

Experience Curve With the Cone Procedure for Ebstein's Anomaly: Effect on Cost and Resource Utilization.

BACKGROUND: The volume-outcome relationship is well-known in health care. The Experience Curve, initially developed by the Boston Consulting … re was no statistically significant change in cardiopulmonary bypass or aortic cross clamp time. In mediation analysis, the reduction in cost was completely accounted for in the decline in ICU length of stay. ICU length of stay was correlated with duration of intubation. CONCLUSIONS: Increasing familiarity with Ebstein's anomaly and Cone reconstruction led to a red …

Annotation and Comparative Genomics of Prokaryotic Transposable Elements.

The data generated in nearly 30 years of bacterial genome sequencing has revealed the abundance of transposable elements (TE) and their importance in genome and transcript remodeling through the mediation of DNA insertions and deletions, structural rearrangements, and regulation of gene expression. Furthermore, what we have learned from studying transposition mechanisms and their regulation in bacterial TE is fundamental to our current understanding of TE in other organisms because much of what has been observed in bacteria is conserved in all domains of life. However, unlike eukaryotic TE, pr