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Disparities in Palliative and Hospice Care and Completion of Advance Care Planning and Directives Among Non-Hispanic Blacks: A Scoping Review of Recent Literature.

ObjectivesPublished research in disparities in advance care planning, palliative, and end-of-life care is limited. However, available data points to significant barriers to palliative and end-of-life care among minority adults. The main objective of this scoping review was to summarize the current published research and literature on disparities in palliative and hospice care and completion of advance care planning and directives among non-Hispanc Blacks.MethodsThe scoping review method was used because currently published research in disparities in palliative and hospice cares as well as adva

Treatment Decision Making at Diagnosis for Children Presenting With Advanced Cancer in Low- and Middle-Income Countries.

PurposeAlthough most children diagnosed with cancer live in low- and middle-income countries (LMICs), research exploring decision making in these settings remains sparse. When children present with advanced cancer in LMICs, local centers may lack resources to provide treatment required to achieve cure. Existing treatment guidelines often do not account for contextual and resource variations influencing decision making. This qualitative study sought to understand physician approaches to treatment decision making for children presenting with advanced cancer at diagnosis in LMICs.MethodsSemistruc

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… training, five completed 1-6 months of training, and six completed over 7 months of training in a high-income country. b For participants who completed training in palliative care, one completed an undergraduate/medical school course, five completed a thematic or postgraduate course without official certification … , and eight completed a certificate course. …

Множественный опыт и предпочтения в области миеломы: исследование смешанных методов лечения пациентов и партнеров по уходу в Соединенных Штатах.

ЦЕЛЬ: Множественная миелома (ММ) характеризуется рецидивом лечения и сопротивлением, что требует принятия последовательных решений о лечении на протяжении всего курса лечения. Для того чтобы понять, каким образом состояние заболеваний и изменение условий лечения влияют на решения, принимаемые пациентами и партнерами по уходу, было проведено исследование по изучению неинтервенционных смешанных методов. ПАТИЕНТЫ И МЕТОДЫ: Пациенты, самоотчитывающиеся MM и партнеры по уходу, были набраны через Гритское сообщество по борьбе с раком, социальные сети и снежные шары для участия в этом исследовании, п

The 2024 Saudi Pharmacotherapy Didactic Curriculum Toolkit: A Modified Delphi Study.

BACKGROUND: Several pharmacy schools in Saudi Arabia (S.A.) refer to the American College of Clinical Pharmacy (ACCP) pharmacotherapy toolkit in developing their pharmacotherapy curriculum. However, the ACCP toolkit does not specifically address the healthcare needs of the Saudi population. A tailored pharmacotherapy curriculum that offers graduates the essential competencies to better serve the nation's needs is warranted. This study aims to develop a population-centered didactic pharmacotherapy toolkit for the Saudi population to assist pharmacy schools in designing pharmacotherapy course co

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… ) Geographical Location Central 32 (57.14) Western 14 (25) Eastern 9 (16.07) Southern 1 (1.79) Northern 0 (0) Additional Degree(s)/ Training (Post-Bachelor) Post Bachelor Pharm.D. 16 (30.19) PGY1 34 (64.15) Master’s degree 11 (20.75) PGY2 41 (77.36) Fellowship 9 (16.98) Others 5 (9.43) Earned Board Certification … Central | 32 (57.14) Western | 14 (25) Eastern | 9 (16.07) Southern | 1 (1.79) Northern | 0 (0) Additional Degree(s)/ Training (Post-Bachelor) | Post Bachelor Pharm.D. | 16 (30.19) PGY1 | 34 (64.15) Master’s degree | 11 (20.75) PGY2 | 41 (77.36) Fellowship | 9 (16.98) Others | 5 (9.43) Earned Board Certification …

Оказание помощи лицам, страдающим множественным склерозом, в Италии: восходящий подход проекта < < Континхом > > .

ЦЕЛЬ: В Италии, вокруг 137,000 Люди живут с множественным склерозом, сталкиваясь с организационными сложностями из-за того, что нынешняя модель уделяет ограниченное внимание уходу в непосредственной близости. Этот проект направлен на определение модели близости в соответствии с последними изменениями в итальянской системе здравоохранения, которая включает в себя: 150 Заинтересованные стороны в области здравоохранения, которые могут оказать 14,000 Пациенты. МЕТОДЫ: Был проведен анализ с целью картирования многоразового склерозового пути, после чего были проведены собеседования для выявления фак

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… Tahan HM, Watson AC, Sminkey PV (2015) What case managers should know about their roles and functions: a national study from the Commission for Case Manager Certification: part 1. Prof Case Manag 20(6):271–296 49. … Tahan HM, Kurland M, Baker M (2020) Understanding the Increasing role and value of the professional case manager: a national study from the Commission for Case Manager Certification: part 1. Prof Case Manag 25(3):133–165 50. …

Technology forecast: advanced therapies in late clinical research, EMA approval or clinical application via hospital exemption.

Background: The umbrella term ATMPs (Advanced Therapy Medicinal Products) comprises cell therapies, gene therapeutics and tissue engineered products. After implementation of the Regulation 1394/2007, only a couple of products have obtained a centralized European marketing authorisation. Objectives: The aim of the presented study is to give an overview on ATMPs available within the European Union either via centralized marketing authorisation or via national Hospital exemption. Additionally, a forecast on innovative ATMPs in the process of EMA approval as well as in phase III and IV clinical tr

Abstracts From JADPRO Live 2019: Washington State Convention Center • Seattle • October 24-27.

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… During this time UCHealth was actively seeking Quality Oncology Practice Initiative (QOPI) certification for its system Oncology Service Line including 5 hospitals across three regions within the state. … Following certification, the QOPI steering committee promptly shifted focus to the proactive preparation for USP implementation, initially scheduled for July 1, 2018 (and later delayed to December 1, 2019). …

Демографическое исследование тенденций заболеваемости миеломой в Соединенных Штатах 2000-2020.

Миэлома one из наиболее распространенных видов гематологических магнатов. Мы намеревались изучить показатели распространенности миеломы в разбивке по полу, расе, возрасту и гистологическим подгруппам в Соединенных Штатах (США) в целом. 2000-2020. Данные были получены из системы наблюдения, эпидемиологии и конечных результатов (SEER) 22 База данных. Вариант Международной классификации болезней для онкологии 3 морфологические коды 9731, 9732, и 9734 Они были назначены для одиночной плазмоцитомы кости, плазменной клеточной миеломы и излишней плазмоцитомы, соответственно. Сообщалось о среднегодово

Саркоидоз и повышенный риск сопутствующих заболеваний и смертности в Швеции.

ВВЕДЕНИЕ: Саркоидоз — это системное воспалительное заболевание с неясной этиологией, включающее образование гранулом. В большинстве случаев оно затрагивает легкие и лимфоузлы в грудной полости. Саркоидоз может протекать в острой или хронической форме, каждая из которых имеет различные клинические проявления и прогноз. МЕТОДЫ: Кейс-контрольное исследование коморбидности и морбидности у лиц, диагностированных с саркоидозом (код ICD10 D86) в Швеции с 2007 по 2016 год. Контроли были сопоставлены с случаями в соотношении 2:1 по возрасту, полу и району диагностики. Данные собрали из Шведского нацио

Abstracts From JADPRO Live at APSHO 2017.

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… There are no specialty standards or certifications for neuro-oncology APs, no formal training programs, and no literature that addresses the competency requirements of neuro-oncology APs. … Methods: A correlational quantitative survey including area of practice, professional background, years in practice, certification, previous experience in EBP, and knowledge of a practice mentor were summarized using descriptive statistics. …

Assessing palliative care needs in adult patients with hematological malignancies and their caregivers: implications for referral practice.

BackgroundPatients with hematological malignancies frequently experience complex physical, psychological, and spiritual concerns due to disease progression and intensive therapies. Despite these needs, palliative care services are often underutilized. This study aimed to assess the palliative care needs of adult patients with hematological malignancies and their caregivers in a tertiary care setting in India.MethodsA descriptive survey was conducted from October 2022 to February 2023, involving 200 patients and their caregivers in oncology wards. The Needs Assessment Tool for Progressive Disea

Определение воздействия методов эмоциональной свободы на сексуальную дисфункцию и самообслуживание женщин, страдающих множественным склерозом.

АИМ: Данное исследование направлено на определение воздействия методов эмоциональной свободы (ЭФТ) на сексуальную дисфункцию и уход за собой у женщин, у которых диагностирован множественный склероз (МС). МЕТОД: Настоящее исследование проводилось с использованием экспериментальной схемы, разработанной до проведения испытаний, включая последующие оценки для оценки устойчивости последствий вмешательства. В выборку входили 16 женщин в возрасте от 19 до 49 лет, которым был поставлен диагноз MS и которые были представлены в неврологическую клинику университетской больницы в Тюркийе в период с октябр

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… Various professional organizations offer certification and training programs; however, there is currently no central authority that universally defines EFT (Feinstein 2009 ). …

Chimeric antigen receptor T-cell therapy: Challenges and framework of outpatient administration.

Adoptive cellular therapy has made a landmark change within the treatment paradigm of several hematologic malignancies, and novel cellular therapy products, such as chimeric antigen receptor T-cell therapy (CART), have demonstrated impressive efficacy and produced durable responses. However, the CART treatment process is associated with significant toxicities, healthcare resource utilization, and financial burden. Most of these therapies have been administered in the inpatient setting due to their toxicity profile. Improved toxicity management strategies and a better understanding of cellular

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… Currently, FACT is encouraging certification for immune effector cell (IEC) therapy if a program is administering research or commercial CART products. …

Preliminary results of a new intercalary modular endoprosthesis for the management of diaphyseal bone metastases.

OBJECTIVES: This study aims to evaluate functional outcomes of patients and to analyze complication rates of modular intercalary endoprosthetic reconstruction after resection of metastatic diaphyseal bone lesions. PATIENTS AND METHODS: Between December 2017 and February 2020, 22 patients (15 males, 7 females; median age: 64.2 years; range, 49 to 91) who underwent reconstruction with modular intercalary endoprostheses for metastatic bone tumors at five different centers were retrospectively analyzed. Age, sex, diagnosis, follow-up duration, previous treatments of patients, and resection length

Female sex is associated with a lower risk of bone metastases and favourable prognosis in non-sex-specific cancers.

BackgroundThe objectives were to investigate the disparity in the prevalence of bone metastases (BM) between the sexes and to assess the effect of female sex on the development and prognosis of BM.MethodsCases of invasive non-sex-specific cancers diagnosed between 2010 and 2015 in the Surveillance, Epidemiology, and End Results (SEER) program were used. The prevalence of BM was calculated by combining the prevalence of BM among different cancers. Multivariable logistic regression and proportion hazard regression were conducted to investigate the effect of female sex, and the results were poole

Disparities in All-Cause Mortality in Older Patients with Colorectal Cancer According to Disability Status: A Nationwide Analysis.

BackgroundAlthough investigating patterns of cancer mortality is important in understanding the effect of cancer on population health, knowledge regarding mortality in cancer patients with disability is scarce. This study examined the association between disability status and all-cause mortality in older patients with colorectal cancer.MethodsData were obtained from the 2008-2019 National Health Insurance Service claims data. The study population included patients with colorectal cancer aged 60 years or above. The outcome measure was all-cause 5-year and overall mortality. A survival analysis

Regulatory insights on gene therapies, adeno-associated virus-based gene therapies, cell/tissue-based products, and medical care/practice in cell and gene therapies: Report from the 7th Asia partnership conference - April 25, 2024.

The 7th Asia Partnership Conference of Regenerative Medicine (APACRM) was held both in person and online on April 25, 2024, to promote the regulatory harmonization of regenerative medicine products across Asia. Recognizing domestic regulatory guidelines and their underlying rationales within each country and region is an important initial step toward achieving harmonious regulation. The 7th APACRM featured open dialogues on the non-clinical evaluations of adeno-associated virus gene therapy products, regulation of gene therapies, considerations for conducting clinical trials, and provision of

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… HSA, Singapore Regulator: Singapore does not require retests; instead, it relies on Certificate of Analysis (CoA) provided by manufacturers. This approach is practical because of the high costs and limited quantities of these products as well as the need for timely administration. … Suggestions were made to enhance the training and certification processes for medical professionals involved in regenerative medicine. Additionally, improving the scientific rigor of therapies through better data collection and more robust clinical studies was emphasized. …

Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas.

Despite recent advances in frontline therapy for diffuse large B-cell lymphoma (DLBCL), at least a third of those diagnosed still will require second or further lines for relapsed or refractory (rel/ref) disease. A small minority of these can be cured with standard chemoimmunotherapy/stem-cell transplant salvage approaches. CD19-directed chimeric antigen receptor T-cell (CAR-19) therapies are increasingly altering the prognostic landscape for rel/ref patients with DLBCL and related aggressive B-cell non-Hodgkin lymphomas. Long-term follow up data show ongoing disease-free outcomes consistent w

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… Center certification is a lengthy and resource-exhaustive process that can take 6–18 months and is fraught with challenges and redundancies [ 36 ]. Analyses show 29–71% of estimated medically eligible rel/ref DLBCL patients, are not treated with a licensed CAR T-cell therapy [ 17 , 37 – 39 ]. … Paving the Road for Chimeric Antigen Receptor T Cells: American Society for Transplantation and Cellular Therapy 80/20 Task Force Consensus on Challenges and Solutions to Improving Efficiency of Clinical Center Certification and Maintenance of Operations for Commercially Approved Immune Effector Cell …

Assessment of Psychiatric Disorders in Consultation-Liaison Setting.

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… previous treatment papers, current MSE, psychometric assessment, application of appropriate screening tools, and rating scales If the above conditions become unremitting, persistent with significant deterioration in quality-of-life and psycho-social-impairment – the patients qualify for disability certificate … Ministry of Social Justice and Empowerment, Government of India Guidelines for Evaluation and Assessment of Mental Illness and Procedure for Certification. (No. 16-18/97-NI); 2002. [Last accessed on 2021 Oct 12]. Available from: http://www.ccdisabilities.nic.in/page . 48. Balhara YP, Dayal P. …

Нарушение порядка сбора кожи и опасное употребление алкоголя.

ОКРУЖАЮЩАЯ СТРУКТУРА: Несостояние кожей характеризуется повторным вымогательством кожи. Несмотря на то, что расстройство, связанное с выбиранием кожи, связано с проблемами, связанными с потреблением веществ, ни в одном из предыдущих исследований не рассматривались связи употребления алкоголя при сборе симптоматологии кожи. МЕТОДЫ: Взрослые, страдающие расстройством, связанным с кожей (n = 182), были набраны из общины в рамках онлайнового обследования. Участники закончили тест на выявление расстройств, связанных с употреблением алкоголя (АУДИТ), для измерения потребления алкоголя и различные са