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Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015.

A1 Introduction to the 2nd synchronicity forum of GHRI/CHVI-funded Canadian and African HIV prevention and vaccine teams O1 Voluntary medica … y Team O9 Secretor status and susceptibility to HIV infections among female sex workers in Nairobi, Kenya Nadia Chanzu, Walter Mwanda, Julius Oyugi, Omu Anzala O10 Natural Killer cell recall responsiveness to Gag-HIV-1 peptides of HIV-1 exposed but uninfected subjects are associated with peripheral CXCR6+ NK cell subsets Moustapha Mbow, Sabelle Jallow, …

Quality of life and its association with anxiety, depression, and clinical factors among patients with metastatic cancer attending oncology centers in Northwest Ethiopia.

BackgroundEnhancing quality of life (QoL) is the primary aim of palliative care and a key endpoint in oncology research.ObjectiveThis study aimed to assess the QoL and its association with anxiety, depression, and clinical factors among patients with metastatic cancer attending oncology centers in Northwest Ethiopia.DesignA cross-sectional study was conducted among 290 cancer patients with metastasis who were receiving treatment at oncologic centers in Northwest Ethiopia from August to October 2023.MethodsStudy participants were enrolled using the consecutive sampling method. QoL was measured

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… This observation aligned with findings from studies conducted in Kenya, 38 Nigeria, 39 and Serbia. 40 The presence of comorbidity could lead to adverse outcomes in conjunction with cancer treatment. … Determinants of quality of life among gynaecological cancer patients on follow up at a referral hospital in Kenya . Science Publishing Group , 2015 . 10 Smith EM Gomm S Dickens C . …

Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 34 cancers in 186 countries.

This article provides updated global cancer statistics for the year 2024 based on the GLOBOCAN estimates of the International Agency for Research on Cancer. The authors describe national cancer incidence and mortality by world region and the Human Development Index and predict the burden in 2050 based on demographic trends. In 2024, an estimated 20.6 million new cancer cases (19.5 million excluding nonmelanoma skin cancer) and 9.8 million deaths (9.7 million excluding nonmelanoma skin cancer) occurred worldwide, equivalent to one in five people developing cancer during their lifetime and one i

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… sexual debut and more partners. 204 , 208 , 209 Cervical cancer incidence remains highest and continues to increase in many sub‐Saharan African countries: Blantyre (Malawi) recorded the fastest rise (7.9% annually), with significant increases also observed in Eastern Cape (South Africa) and Eldoret (Kenya … DNA testing, supporting the scaling‐up of screening and treatment services for women who remain unvaccinated and at the highest risk. 216 , 217 , 218 As of March 2026, 91 of the 194 countries with national HPV vaccination programs have adopted single‐dose schedules. 219 For example, in November 2025, Kenya …

Health and economic impact of caregiving on informal caregivers of people with chronic diseases in sub-Saharan Africa: A systematic review.

With a disproportionate burden of chronic diseases and severe shortage of health workers in sub-Saharan Africa, the region implicitly relies on informal caregivers (ICGs) to support the patients both within and outside the health facilities. The aim of this review is to systematically summarise evidence on the health and economic impact of caregiving on informal caregivers of patients with chronic diseases in sub-Saharan Africa. Medline (Ovid), CINAHL (EBSCOhost), PsycINFO (Ovid), Embase (Ovid), Global Health, and Web of Science databases were systematically searched to identify original artic

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… Muriuki (2023) [ 52 ], Kenya | Quantitative (Health facility outpatients) | Family caregivers Mean age: Not reported Age range: 18 to >61 years Sex: Female 147 (57.6%) Employment: Employed 109 (42.8%), Unemployed 146 (57.3%) | 255 | Cancer (not specified) | Not reported | at least 2 weeks | Not reported … Assessment of role strain among family caregivers of adult patients with cancer at a national referral hospital in Kenya . Psychooncology [Internet]. 2023 Jan 30 [cited 2023 Jul 31]; 32 ( 1 ): 42 – 6 . …

The global prevalence of peripheral neuropathy following chemotherapy in cancer patients: a systematic review and meta-analysis.

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a major cause of dose reduction, drug modification, or drug discontinuation in cancer patients which negatively impacts the overall well-being of cancer patients and medication procedures. This systematic review and meta-analysis investigation aimed to determine the global prevalence of CIPN in cancer patients. METHODS: Various scientific databases (PubMed, Scopus, Web of Science, Embase, ScienceDirect, and Google Scholar) were systematically searched (by July 2023) for published studies reporting the CIPN prevalence. Meta-analys

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… Colombia 57 ± 13 1,551 “patients’ medical records” (49.9%) - - 17 Huang et al. [ 26 ] 2018 USA 31.8 ± 8.4 2811 CTCAE (9%) - - 18 Hong et al. [ 27 ] 2019 China - 254 CIPNAT (74.02%) - - 19 Haidinger et al. [ 28 ] 2019 Germany median: 49 ,20–81 1,122 unknown survey (65–69%) - - 20 Ezzi et al. [ 29 ] 2019 Kenya … | - 17 | Huang et al. [ 26 ] | 2018 | USA | 31.8 ± 8.4 | 2811 | CTCAE (9%) | - | - 18 | Hong et al. [ 27 ] | 2019 | China | - | 254 | CIPNAT (74.02%) | - | - 19 | Haidinger et al. [ 28 ] | 2019 | Germany | median: 49 ,20–81 | 1,122 | unknown survey (65–69%) | - | - 20 | Ezzi et al. [ 29 ] | 2019 | Kenya …

Healing Environments for Cancer Care: Toward a Patient-Centered Design Guideline for Inpatient Settings.

ObjectivesThis study proposes an evidence-based design guideline for oncology inpatient rooms that addresses the physical, emotional, and psychosocial needs of cancer patients.BackgroundCancer inpatients frequently experience long hospital stays with emotional vulnerability and clinical stress. Growing evidence suggests environmental design can shape patient experience, comfort, and recovery. Yet, current literature lacks an integrated framework for the spatial and sensory needs of this population.MethodA systematic literature review was conducted across Web of Science, Scopus, and PubMed. Fro

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… Quantitative | Retrospective registry cohort | In-patients | ( Tsai et al., 2021 ) 21 | 2009 | USA | N/A | Qualitative | Narrative review | N/A | ( Partridge-Hinckley et al., 2009 ) 22 | 2023 | China | China | Quantitative | Retrospective pre/postcohort | Patients | ( Zhao et al., 2023 ) 23 | 2017 | Kenya … | Kenya | Mixed | Mixed survey and FGDs | In-patients | ( Keiza et al., 2017 ) 24 | 2011 | USA | USA | Quantitative | Case environmental monitoring | In-patients | ( Linder & Christian, 2011 ) 25 | 2023 | USA | USA | Quantitative | Quasi-exp. metagenomics | N/A | ( Wright et al., 2023 ) 26 | 2025 | …

Transforming hematology care in LMICs: strategies for enhanced diagnosis and treatment.

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… Several countries, including Nigeria, Ghana, Kenya, Uganda, and Tanzania, have introduced newborn screening programs, hydroxyurea treatment initiatives, and laboratory strengthening strategies to improve hematology services ( 11 , 20 ). …

Оценка стабильности урожая генотипов пшеницы пальца методом анализа AMMI и GGE биоплота в различных условиях среды.

Производительность пшеницы пальца сильно зависит от взаимодействия генотипа × среды (GEI), что усложняет идентификацию высокопродуктивных и стабильных генотипов. В данном исследовании оценены 35 генетически разнообразных генотипов пшеницы пальца в трех агро-эко-зоне: Одиша (E1), ДжхаркHAND (E2) и Бихар (E3) в течение двух рахи сезонов (2023-24 и 2024-25). Использовался блочный дизайн с тремя повторами, и были зафиксированы ключевые количественные признаки, такие как урожайность на растение, вес 1000 зерен и количество пальцев на основной узле. Применены анализы AMMI и GGE биоплотов для оценки

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… At present, it is extensively grown in countries such as India, Nepal, Ethiopia, Uganda, and Kenya. It is commonly known as “ragi” in India, “dagussa” in Ethiopia, and “wimbi” in Kenya. …

Interventions for improving coverage of childhood immunisation in low- and middle-income countries.

BACKGROUND: Immunisation plays a major role in reducing childhood morbidity and mortality. Getting children immunised against potentially fa … co, Guatemala), 11 lower-middle-income countries (Côte d'Ivoire, Ghana, Honduras, India, Indonesia, Kenya, Nigeria, Nepal, Nicaragua, Pakistan, Zimbabwe), and three lower-income countries (Afghanistan, Mali, Rwanda). The interventions evaluated in the studies were health education (seven studies), patient reminders (13 studies), digital register (two st …

Efficacy of a bivalent (D614 + B.1.351) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, parallel, randomised, modified double-blind, placebo-controlled trial.

BACKGROUND: COVID-19 vaccines with alternative strain compositions are needed to provide broad protection against newly emergent SARS-CoV-2 variants of concern. This study aimed to describe the clinical efficacy and safety of a bivalent SARS-CoV-2 recombinant protein vaccine as a two-injection primary series during a period of circulation of the omicron (B.1.1.529) variant. METHODS: We conducted a phase 3, parallel, randomised, modified double-blind, placebo-controlled trial in adults aged 18 years or older at 54 clinical research centres in eight countries (Colombia, Ghana, India, Kenya, Mex…

Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections.

BACKGROUND: Cesarean delivery is one of the most common surgical procedures performed by obstetricians. Infectious morbidity after cesarean … erformed in 10 different countries (Saudi Arabia, Pakistan, Iran, Thailand, Turkey, USA, Egypt, UK, Kenya and India). The overall risk of bias was low for areas of attrition, reporting, and other bias. About half of the trials had low risk of selection bias, with most of the remainder rated as unclear. Due to lack of blinding, we rated performance bias …

Models of care for children and adolescents with type 1 diabetes in low- and middle-income countries: a scoping review.

BACKGROUND: In order to improve the outcomes of children and adolescents with type 1 diabetes mellitus (T1DM), access to and quality of comp … 19 LMICs across the different WHO regions. African Region We identified models of care in Cameroon, Kenya, Rwanda, Tanzania, and Uganda, largely supported by international initiatives like Changing Diabetes in Children (CDiC) and Life for a Child (LFAC). Models were implemented between 2004 and 2012, and aimed to enhance infrastructure and care delivery …

Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance.

BACKGROUND: The World Health Organization (WHO) recommends treating all school children at regular intervals with deworming drugs in areas w … adds the DEVTA trial from India, and draws on an independent analytical replication of a trial from Kenya. MAIN RESULTS: We identified 45 trials, including nine cluster-RCTs, that met the inclusion criteria. One trial evaluating mortality included over one million children, and the remaining 44 trials included a total of 67,672 participants. Eight tria …

Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment.

BACKGROUND: Pregnancy increases the risk of malaria and this is associated with poor health outcomes for both the mother and the infant, esp … trials were conducted between 1957 and 2008, in Nigeria (three trials), The Gambia (three trials), Kenya (three trials), Mozambique (two trials), Uganda (two trials), Cameroon (one trial), Burkina Faso (one trial), and Thailand (two trials). Six different antimalarials were evaluated against placebo or no intervention; chloroquine (given weekly), pyrim …

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be lived in good health, and the complementary measure of disability-adjusted life-years (DALYs), a composite measure of disease burden capturing both premature mortality and prevalence and severity of ill

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… Subnational estimation in GBD 2017 includes five new countries (Ethiopia, Iran, New Zealand, Norway, and Russia) and countries previously estimated at subnational levels (GBD 2013: China, Mexico, and the UK [regional level]; GBD 2015: Brazil, India, Japan, Kenya, South Africa, Sweden, and the USA; and … To meet data use requirements, we present all subnational estimates excluding those pending publication (Brazil, India, Japan, Kenya, Mexico, Sweden, the UK, and the USA); these results are presented in appendix tables and figures ( appendix 2 ). …

Intestinal Coccidian Infections in Cancer Patients: A Case Series.

Introduction Coccidian protozoa and microsporidian fungi are opportunistic pathogens increasingly implicated in infections in immunosuppressed individuals. These parasites typically infect the intestinal epithelium, resulting in secretory diarrhea and malabsorption. The disease burden and timeline are both greater and longer among immunosuppressed patients. Therapeutic options for immunocompromised individuals are limited. As a result, we wanted to better characterize the disease course and treatment efficacy of these parasitic gastrointestinal infections. Methods We performed a single-center,

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… Social and gender determinants of risk of cryptosporidiosis, an emerging zoonosis, in Dagoretti, Nairobi, Kenya. Kimani VN, Mitoko G, McDermott B, et al. Trop Anim Health Prod. 2012;44 Suppl 1:0–23. doi: 10.1007/s11250-012-0203-4. 24. …

A single-center 7-year experience with end-stage renal disease care in Nigeria-a surrogate for the poor state of ESRD care in Nigeria and other sub-saharan african countries: advocacy for a global fund for ESRD care program in sub-saharan african countries.

Background. A single-center ESRD care experience in a Nigerian teaching hospital is presented as a surrogate case to demonstrate the prevailing ESRD care situation in Nigeria and most SSA countries. Methods. The data of 320 consecutive ESRD patients undergoing maintenance haemodialysis treatment during a seven-year period were retrospectively analyzed. Results. Over 80% of the subjects funded dialysis treatments from direct out of pocket payment. The mean duration on dialysis before dropout was 5.2 ± 7.6 weeks, with majority 314 (98.1%) of the patients unable to sustain dialysis above 12 weeks

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… Others are Zimbabwe (59), Kenya (100), and Sudan (200). South Africa is the only SSA country with a more reliable ESRD data and much higher access to organized ESRD care. …

Community views on mass drug administration for soil-transmitted helminths: a qualitative evidence synthesis.

BACKGROUND: Soil-transmitted helminth (STH) infections are amongst the most common infectious diseases worldwide, with an estimated 24% of t … display our findings. MAIN RESULTS: We included 17 studies, conducted in Bangladesh, Benin, India, Kenya, Malawi, Nigeria, the Philippines, and Turkey. Four themes emerged, three of which were identified in the review of MDA for lymphatic filariasis. People weigh up the benefits and harms in their decision to participate in MDA, though some may not hav …

Circumcision devices versus standard surgical techniques in adolescent and adult male circumcisions.

BACKGROUND: Medical circumcisions are among the most common surgical procedures performed in males. The usual indications are phimosis (inab … RESULTS: Eighteen trials met the inclusion criteria. Trials were conducted in China, South Africa, Kenya and Zambia, Mozambique, Rwanda, Uganda and Zimbabwe. Primary outcomes Serious adverse events: there were no serious adverse events in either treatment arm (11 trials, 3472 participants). Moderate adverse events: there may be a slight increase in mod …