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Donor Evaluation for Hematopoietic Stem and Progenitor Cell Collection

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… Burundi Cameroon Cape Verde Central African Republic Chad Congo (Congo-Brazzaville) Côte d’Ivoire Democratic Republic of the Congo (Congo-Kinshasa) Equatorial Guinea Gabon Gambia Ghana Guinea Guinea-Bissau Kenya Liberia Mali Niger Nigeria Rwanda Senegal Sierra Leone South Sudan Sudan Tanzania Togo Uganda … Burundi Cameroon Cape Verde Central African Republic Chad Congo (Congo-Brazzaville) Côte d’Ivoire Democratic Republic of the Congo (Congo-Kinshasa) Equatorial Guinea Gabon Gambia Ghana Guinea | Guinea-Bissau Kenya Liberia Mali Niger Nigeria Rwanda Senegal Sierra Leone South Sudan Sudan Tanzania Togo Uganda …

Повышение уровня информированности и знаний о раке в Йоханнесбурге и округах iLembe с помощью целенаправленных просветительских мероприятий на уровне общин: экспериментальное исследование.

В Южной Африке рак по-прежнему вызывает все большую озабоченность в области общественного здравоохранения, особенно в недостаточно обслуживаемых общинах, где различия в уровне информированности и доступе к медицинскому обслуживанию приводят к задержкам в диагностике. В рамках этого исследования была проведена оценка воздействия ориентированной на культурные особенности просветительской деятельности на основе адаптированного модуля исследований и просвещения по вопросам доступа к информации о раковых заболеваниях (c-CARE) в районах Йоханнесбурга и iLembe. Было проведено экспериментальное исслед

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… Mapping awareness of breast and cervical cancer risk factors, symptoms and lay beliefs in Uganda and South Africa. PLoS ONE. 2020;15:e0240788. doi: 10.1371/journal.pone.0240788. 11. Nnaji C.A., Kuodi P., Walter F.M., Moodley J. …

Impact of facilitating continued accessibility to cancer care during COVID-19 lockdown on perceived wellbeing of cancer patients at a rural cancer center in Rwanda.

During the COVID-19 pandemic in Rwanda, Partners In Health Inshuti Mu Buzima collaborated with the Butaro Cancer Center of Excellence (BCCOE) to mitigate disruptions to cancer care by providing patients with free transportation to treatment sites and medication delivery at patients' local health facilities. We assessed the relationship between facilitated access to care and self-reported wellbeing outcomes. This cross-sectional telephone survey included cancer patients enrolled at BCCOE in March 2020. We used linear regression to compare six dimensions of quality of life (EORTC QLQ-C30), depre

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… Psychometric properties of the EORTC QLQ-C30 in Uganda . Health Qual Life Outcomes . 2021 ; 19 ( 1 ): 131 . doi: 10.1186/s12955-021-01769-x 33892718 PMC8066473 63 Hinz A , Mehnert A , Kocalevent RD , Brähler E , Forkmann T , Singer S , et al . …

A global, regional, and national survey on burden and Quality of Care Index (QCI) of hematologic malignancies; global burden of disease systematic analysis 1990-2017.

BackgroundHematologic malignancies (HMs) are a heterogeneous group of cancers that comprise diverse subgroups of neoplasms. So far, despite the major epidemiologic concerns about the quality of care, limited data are available for patients with HMs. Thus, we created a novel measure-Quality of Care Index (QCI)-to appraise the quality of care in different populations.MethodsThe Global Burden of Disease data from 1990 to 2017 applied in our study. We performed a principal component analysis on several secondary indices from the major primary indices, including incidence, prevalence, mortality, ye

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… Considering the GDR variety between different countries, we see the highest GDR in Namibia and Uganda, and the lowest GDR in Mongolia and Sweden (Fig. 3 d, and Additional file 7 : Figure S3A-E). …

Keyword Index for Volume 90

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… gene therapy 2210 tumour hypoxia 2232 tumour latency 2219 tumour marker 1877 tumour necrosis factor 853, 906 tumour necrosis factor-alpha 183 tumour vaccine 1636 tumour vasculature 430 tumour vessel 549 tumour-associated antigens 263 Turkmen 1402 tyrosine kinase 189, 1620, 2250 UFT 1003 Uganda …

Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults.

BACKGROUND: Xpert MTB/RIF Ultra (Xpert Ultra) and Xpert MTB/RIF are World Health Organization (WHO)-recommended rapid nucleic acid amplifica … of which nine evaluated both tests. Most studies were conducted in China, India, South Africa, and Uganda. Overall, risk of bias was low for patient selection, index test, and flow and timing domains, and low (49%) or unclear (43%) for the reference standard domain. Applicability for the patient selection domain was unclear for most studies because we w …

Clinical Presentation and Causes of Non-traumatic Spinal Cord Injury: An Observational Study in Emergency Patients.

Introduction: Diagnosing non-traumatic spinal cord injury (NTSCI) is often challenging. However, clear discrimination from non-spinal pathologies, e.g., "myelopathy-mimics" (MMs), is critical in preventing long-term disability and death. In this retrospective study we (1) investigated causes of NTSCI, (2) identified clinical markers associated with NTSCI and (3) discuss implications for NTSCI management. Methods: Our sample consisted of 5.913 consecutive neurological and neurosurgical patients who were treated in our emergency department during a one-year period. Patients with a new or worsene

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… Epidemiology of non-traumatic spinal cord injury in Uganda: a single center, prospective study with MRI evaluation. BMC Neurol. (2019) 19:1–7. 10.1186/s12883-019-1236-3 5. Smith É, Fitzpatrick P, Lyons F, Morris S, Synnott K. …

The impact of mHealth interventions on medication adherence in breast cancer: a systematic review of randomized controlled trials.

BackgroundNon-adherence to medication can reduce therapeutic effectiveness in breast cancer patients, thereby increasing the risk of disease progression or recurrence. This study aimed to systematically review the existing scientific literature on the impact of mHealth interventions on medication adherence among breast cancer patients.MethodsThis systematic review was conducted following PRISMA guidelines and focused on randomised clinical trials published in English. The review evaluated the effectiveness of mHealth interventions in improving medication adherence in breast cancer patients fro

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… Feasibility of a short message service (SMS) intervention to deliver tuberculosis testing results in peri-urban and rural Uganda. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases , 16, 100110. 10.1016/j.jctube.2019.100110 Brown, M. T., & Bussell, J. K. (2011). …

Managing emotional and physical stress in sickle cell anemia: a review of effective strategies and approaches.

Sickle cell anemia (SCA) is a genetic blood disorder characterized by recurrent pain episodes, chronic complications, and significant emotional and physical stress. This review article explores effective strategies for managing both the emotional and physical aspects of stress in SCA patients. A comprehensive literature search was conducted across multiple databases, including PubMed, Scopus, and Google Scholar, using keywords such as "sickle cell anemia", "stress management", "psychological support", and "pain management". Emotional stress in SCA arises from chronic pain, frequent hospitaliza

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… Psycho-social challenges faced by caretakers of children and adolescents aged 0–19 years with sickle cell disease admitted in a tertiary hospital in Eastern Uganda . J Pediatr Nurs 2023 ; 69 : e21 – 31 . 36463013 10.1016/j.pedn.2022.11.026 [7] Ahmed SG Ibrahim UA . …

A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors.

Observational and ecological studies are generally used to determine the presence of effect of cancer risk-modifying factors. Researchers generally agree that environmental factors such as smoking, alcohol consumption, poor diet, lack of physical activity, and low serum 25-hdyroxyvitamin D levels are important cancer risk factors. This ecological study used age-adjusted incidence rates for 21 cancers for 157 countries (87 with high-quality data) in 2008 with respect to dietary supply and other factors, including per capita gross domestic product, life expectancy, lung cancer incidence rate (an

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… Lebanon, Lesotho, Libya, Madagascar, Maldives, Mali, Malta, Martinique, Mauritania, Moldova, Morocco, Mozambique, Myanmar, Namibia, Nepal, New Caledonia, Niger, Nigeria, Pakistan, Papua New Guinea, Reunion, Saudi Arabia, Senegal, Sierra Leon, Solomon Islands, Sudan, Tanzania, Thailand, Togo, Tunisia, Uganda …

Health Risks from Microplastics in Intravenous Infusions: Evidence from Italy, Spain, and Ecuador.

The rising incidence of microplastics (MPs) is a possible health risk to humans. The present study aims to analyze the presence of MPs in intravenous (IV) infusions and compare MP concentrations from multiple brands. The IV solutions of 29 medical devices (IV-MDs) from seven brands commercialized in Ecuador, Spain, and Italy have been selected under specific consideration to carry out the study. The detection of MPs has been quite obvious in almost all of the samples from brands in the mentioned countries. MP concentrations ranged from 9 to 20 MPs/L in glass containers to 166-299 MPs/L in plas

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… India leads global exports of glucose and NaCl infusions to countries like Ghana, Tanzania, and Uganda. Germany, the UK, and France are key European markets due to their strong healthcare infrastructure. Canada and Japan are projected to grow at annual rates of 6.3% and 5.6%, respectively. …

Psychological Resilience, Symptom Burden, and Supportive Care Needs in Chemotherapy Patients: A Path Analysis

ABSTRACT Introduction and Aim While chemotherapy contributes to the survival of cancer patients, it also leads to various psychological and physiological problems, increasing the need for supportive care. This study aimed to determine the relationship between psychological resilience, chemotherapy symptoms, and supportive care needs in patients undergoing chemotherapy. Method This is a descriptive and correlational study. Data were collected using the Descriptive Characteristics Form, the Psychological Resilience Scale (PRS), the Nightingale Symptom Assessment Scale (N‐SAS), and the Supportive

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… “Health‐Related Quality of Life Among Adult Patients With Cancer in Uganda—A Cross‐Sectional Study.” Global Health Action 17, no. 1: 2325728. https://www.tandfonline.com/doi/full/10.1080/16549716.2024.2325728 . Ölmez, N. , and Karadağ E.. 2022. …

Facilitators and barriers to provision of hospital in the home: does geographical location matter? A scoping review.

BackgroundThere is an increasing imperative for hospital services delivered in the home due to overburdened hospital systems, ageing populations and rising prevalence of chronic disease. Hospital in the home services have numerous advantages including reduced mortality, reduced hospital readmission and emergency department presentations and improved patient quality of life. Despite anticipated benefits for rural communities, which typically experience high prevalence of chronic disease and high rates of potentially avoidable hospitalisation, there appears to be limited research that focusses s

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… . | Jang [ 37 ] | 2013 | Sub-Saharan Africa (mainly Uganda, South Africa) | Review (literature, scoping, systematic etc.) | NA | Palliative care | Health professional, policy advisor/health system Resource utilization and cost analyses of home-based palliative care service provision: the Niagara West …

State of the art biology, progression, and clinical management of monoclonal B-cell lymphocytosis (MBL): consensus report from the Intercepting Blood Cancers Workshop Committee.

In March 2023 and 2024, a panel of international experts convened at the first and second Intercepting Blood Cancers (IBC) Workshops, with the aim of better appreciating the diagnostic challenges, pathophysiology, and potential therapeutic interventions for precursor malignant hematology conditions. Here, we report a summary of the proceedings from the sessions focused on monoclonal B-cell lymphocytosis (MBL)/chronic lymphocytic leukemia (CLL). We highlight four main content areas: biology of MBL, clinical implications of MBL, progression of MBL and transformation from indolent CLL to aggressi

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… In a cross-sectional study of hospital-based populations in the United Kingdom and rural Uganda, the overall prevalence of MBL was higher in the Ugandan cohort than the United Kingdom cohort (14% versus 8%), and notably a higher prevalence of an atypical CD5-negative immunophenotype MBL was observed …

Development and psychometric properties of a general cancer stigma scale.

Cancer stigma negatively impacts diagnosis, quality of life, and survival outcomes, yet stigma reduction efforts are hindered by the lack of a valid and universal scale to measure cancer stigma. This study aimed to develop and validate a global cancer stigma scale, the Cross-Cultural Oncology Measure for Perception and Awareness of Stigma Scale (COMPASS), which measures internalized, anticipated, and enacted stigma. The scale was developed using mixed methods in two phases: (1) feedback from experts and people with cancer on an initial pool of items, and (2) psychometric validation with people

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… Exploring stigma as a barrier to cancer service engagement with breast cancer survivors in Kampala, Uganda. Psychooncology. 2016;25(10):1206‐1211. doi: 10.1002/pon.4215 18. Suneja G, Kimani SM, Gill H, Painschab MS, Knettel BA, Watt MH. …

Repurposing Drugs in Oncology (ReDO)-mebendazole as an anti-cancer agent.

Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. Significantly, there are also two case reports of anti-cancer activity in humans. The data are summarised and discussed in relation to suggested mechanisms of action. Based on the evidence presented, it is proposed that mebendazole would synergise with a range of other drugs, including existing chemotherapeutics, and that further exploration of the potential of mebendazole as an anti-cancer

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… Namwanje H Kabatereine NB Olsen A Efficacy of single and double doses of albendazole and mebendazole alone and in combination in the treatment of Trichuris trichiura in school-age children in Uganda Tran R Soc Trop Med Hyg 2011 105 10 586 590 10.1016/j.trstmh.2011.07.009 21885077 10. …

An evaluation based on the analytic hierarchy process and GGEbiplot on French fry potato genotypes in Yunnan, China.

A total of 33 potato (Solanum tuberosum L.) cultivars and breeding clones imported from the United States and two local cultivars (Yunshu 401 and Cooperation 88, CK) were planted and evaluated. To determine their suitability for processing into French fries at five locations (e1-e5) in Yunnan Province, China, we developed a comprehensive evaluation system using the analytical hierarchy process (AHP). Eleven evaluation indicators for French fry quality, yield, and agronomic characteristics with a relative importance (weight coefficients) of 0.483, 0.301 and 0.216, respectively, were used to ana

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… “Processing traits of potato varieties grown in Uganda for potential production of French fries,” in Masters dissertation (Makerere University; ). Buciumeanu E. C., Vizitiu D. E., DincĂ L., Radomir A. M. (2021). …

The Disruptive Impact of COVID-19 on the Utilization of Cancer Chemotherapy-Related Healthcare Assistance at the Principal Nationwide Referral Hospital in Kenya.

Background Lockdown measures to reduce the outbreak of COVID-19 negatively impacted the administration of cancer chemotherapy globally; however, data from Kenya are limited. Researchers strove to address this information gap and assess chemotherapy trends before and during the pandemic at Kenyatta National Hospital (KNH), the most wide-ranging referral infirmary in Kenya, along with associated factors to provide future guidance. Methods Time series analyses and patient interviews were undertaken at the KNH Cancer Treatment Centre. Patient data were analyzed descriptively and inferentially. The

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… COVID-19 pandemic and the widening gap to access cancer services in Uganda. Abila DB, Ainembabazi P, Wabinga H. https://pubmed.ncbi.nlm.nih.gov/33193955/ Pan Afr Med J. 2020;35:140. doi: 10.11604/pamj.supp.2020.35.140.25029. 50. …

Оценка стабильности урожая генотипов пшеницы пальца методом анализа AMMI и GGE биоплота в различных условиях среды.

Производительность пшеницы пальца сильно зависит от взаимодействия генотипа × среды (GEI), что усложняет идентификацию высокопродуктивных и стабильных генотипов. В данном исследовании оценены 35 генетически разнообразных генотипов пшеницы пальца в трех агро-эко-зоне: Одиша (E1), ДжхаркHAND (E2) и Бихар (E3) в течение двух рахи сезонов (2023-24 и 2024-25). Использовался блочный дизайн с тремя повторами, и были зафиксированы ключевые количественные признаки, такие как урожайность на растение, вес 1000 зерен и количество пальцев на основной узле. Применены анализы AMMI и GGE биоплотов для оценки

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… At present, it is extensively grown in countries such as India, Nepal, Ethiopia, Uganda, and Kenya. It is commonly known as “ragi” in India, “dagussa” in Ethiopia, and “wimbi” in Kenya. …