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Staff perspectives on the feasibility of a clinical pathway for anxiety and depression in cancer care, and mid-implementation adaptations.

BackgroundClinical pathways (CPs) are intended to standardise and improve care but do not always produce positive outcomes, possibly because they were not adapted to suit the specific context in which they were enacted. This qualitative study aimed to explore staff perspectives of implementation of a CP for routine screening, assessment, referral and management of anxiety and depression (the ADAPT CP) for patients with cancer, focussing on perceived feasibility of the CP and negotiated adaptations made during the implementation phase.MethodsThe ADAPT CP was implemented in 12 urban and regional

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… Management, Program Coordinator, Practice Manager Psychosocial staff: Psychologist, Psychologist Intern, Social Worker, Counsellor b Other languages spoken at home: Spanish, Mandarin, Cantonese, Indonesian, Portuguese, Tagalog, Malayalam c Other countries of birth: UK, China, India, Indonesia, Brazil, Kenya …

Treatment Decision Making at Diagnosis for Children Presenting With Advanced Cancer in Low- and Middle-Income Countries.

PurposeAlthough most children diagnosed with cancer live in low- and middle-income countries (LMICs), research exploring decision making in these settings remains sparse. When children present with advanced cancer in LMICs, local centers may lack resources to provide treatment required to achieve cure. Existing treatment guidelines often do not account for contextual and resource variations influencing decision making. This qualitative study sought to understand physician approaches to treatment decision making for children presenting with advanced cancer at diagnosis in LMICs.MethodsSemistruc

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… Kizyma MD (Clinical Center of Children's Healthcare, Lviv, Ukraine); Essy Maradiege, MD (Cancer Prevention and Control Directorate - Ministry of Health, Lima, Peru); Hoa Thi Kim Nguyen, MD, PhD (Hue Central Hospital, Hue, Vietnam); Irene Nzamu, MBChB, MMed, FPHO (Kenyatta National Hospital, Nairobi, Kenya …

Impact of facilitating continued accessibility to cancer care during COVID-19 lockdown on perceived wellbeing of cancer patients at a rural cancer center in Rwanda.

During the COVID-19 pandemic in Rwanda, Partners In Health Inshuti Mu Buzima collaborated with the Butaro Cancer Center of Excellence (BCCOE) to mitigate disruptions to cancer care by providing patients with free transportation to treatment sites and medication delivery at patients' local health facilities. We assessed the relationship between facilitated access to care and self-reported wellbeing outcomes. This cross-sectional telephone survey included cancer patients enrolled at BCCOE in March 2020. We used linear regression to compare six dimensions of quality of life (EORTC QLQ-C30), depre

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… Challenges for cancer care during COVID-19 pandemic in Kenya: Policy implications . J cancer policy . 2020/07/28. 2020 Sep ; 25 : 100247 . doi: 10.1016/j.jcpo.2020.100247 32834996 PMC7385499 8 Martei YM , Rick TJ , Fadelu T , Ezzi MS , Hammad N , Quadri NS , et al . …

Stakeholder perspectives and requirements to guide the development of digital technology for palliative cancer services: a multi-country, cross-sectional, qualitative study in Nigeria, Uganda and Zimbabwe.

IntroductionCoverage of palliative care in low and middle-income countries is very limited, and global projections suggest large increases in need. Novel approaches are needed to achieve the palliative care goals of Universal Health Coverage. This study aimed to identify stakeholders' data and information needs and the role of digital technologies to improve access to and delivery of palliative care for people with advanced cancer in Nigeria, Uganda and Zimbabwe.MethodsWe conducted a multi-country cross-sectional qualitative study in sub-Saharan Africa. In-depth qualitative stakeholder intervi

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… Nurse-led palliative care for HIV-positive patients taking antiretroviral therapy in Kenya: a randomised controlled trial. Lancet HIV. 2015;2(8):e328–e334. doi: 10.1016/S2352-3018(15)00111-3. 12. Gomes B, Calanzani N, Higginson IJ. …

Материалы Международного общества по картированию раковых заболеваний (ИСИС) 18th Ежегодный учебный курс: Ментон, Франция. 7-9 октябрь 2018

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Изменчивость генотипов кассавы (Manihot Escelenta [Cranz]) для состава питания в юго-западной Эфиопии.

В ходе исследования было использовано в общей сложности 100 Генотипы кассавы, полученные из МИТА, Нигерия (биофортифицированные генотипы), и собранные на месте земли Эфиопии, сохранены в Центре сельскохозяйственных исследований Джиммы. Таким образом, понимание изменчивости состава рациона питания может служить ориентиром для будущего генетического совершенствования и поддерживать развитие питательных разновидностей маниоки. Цель этого исследования заключалась в оценке изменчивости генотипов кассавы на основе их анализа состава питательных веществ. Анализ различий (АНОВА) выявил весьма значител

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… . & Nutritional Composition Antinutritive Compounds, and Starch Properties of Flour from Cassava Varieties Grown in Nakuru County, Kenya. 10.21203/rs.3.rs-3606733/v1 (2023). 26. …

Proceedings of the International Cancer Imaging Society Meeting and 21st Annual Teaching Course : Boston, MA, USA. 12-14 September 2022

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… Waweru University of Nairobi, Nairobi, Kenya Correspondence: T.M. …

Analysis of the distribution of malignant tumor burden across eight systems in Africa: an epidemiological analysis based on the Global Burden of Disease Study 1990-2021.

ObjectiveAfrica, a continent abundant in natural resources yet facing economic and cultural challenges. This study investigates the burden of cancer in Africa, leveraging data from the Global Burden of Disease Study 2021 to highlight the need for targeted healthcare interventions and policy reforms.Materials and methodsWe analyzed cancer incidence, prevalence, mortality rates, and Disability-Adjusted Life Years per 100 000 population across 54 African countries from 1990 to 2021. The study categorized malignancies into eight major organ systems and utilized the Social Demographic Index (SDI) t

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… Bone and joint cancers are most prevalent in Egypt with an ASIR of 1.70, with Kenya (ASIR = 1.53) and Ethiopia (ASIR = 1.51) also showing higher rates relative to other regions (Fig. 1 ). …

A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors.

Observational and ecological studies are generally used to determine the presence of effect of cancer risk-modifying factors. Researchers generally agree that environmental factors such as smoking, alcohol consumption, poor diet, lack of physical activity, and low serum 25-hdyroxyvitamin D levels are important cancer risk factors. This ecological study used age-adjusted incidence rates for 21 cancers for 157 countries (87 with high-quality data) in 2008 with respect to dietary supply and other factors, including per capita gross domestic product, life expectancy, lung cancer incidence rate (an

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… , Bangladesh, Benin, Bolivia, Botswana, Burkina Faso, Burundi, Cambodia, Cameroon, Cape Verde, Central African Republic, Chad, Chile, China, Comoros, Djibouti, Ethiopia, French Polynesia, Gabon, Gambia, Ghana, Guadeloupe, Guinea, Guinea-Bissau, Honduras, India, Indonesia, Iraq, Ivory Coast, Jordan, Kenya …

An overview of cancer health disparities: new approaches and insights and why they matter.

Cancer health disparities remain stubbornly entrenched in the US health care system. The Affordable Care Act was legislation to target these disparities in health outcomes. Expanded access to health care, reduction in tobacco use, uptake of other preventive measures and cancer screening, and improved cancer therapies greatly reduced cancer mortality among women and men and underserved communities in this country. Yet, disparities in cancer outcomes remain. Underserved populations continue to experience an excessive cancer burden. This burden is largely explained by health care disparities, lif

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… Sawe, R.T. et al. (2016) Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration. BMC Cancer, 16, 204. 174. …

First Clinical Nutrition Outpatient Consultation: A Review of Basic Principles in Nutritional Care of Adults with Hematologic Disease.

MethodsA bibliographic survey was carried out between 2020 and 2022 using two databases: PubMed/MEDLINE and Scientific Electronic Library Online (SciELO) and the information source Academic Google, irrespective of language or geography.ResultsIn the first nutrition consultation (FNC), there should be an investigative direction focused on nutritional interventions in the short, medium, and long term. The record in the patient's medical record is relevant for carrying out the consultation, according to the recommendations of the normative councils of medicine and nutrition. The main steps to be

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… Vitamin D deficiency causes rickets in an urban informal settlement in Kenya and is associated with malnutrition Maternal and Child Nutrition 2018 14 1 e12452 10.1111/mcn.12452 2-s2.0-85018271704 PMC5763407 28470840 150 Guedeney A. …

Effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer: A systematic review and meta-analysis.

BackgroundTelehealth is being integrated with palliative care for patients with advanced cancer to improve access to specialized palliative care. However, its effectiveness and implementation requirements in palliative care remain unclear.AimThis study evaluates the effectiveness of and implementation requirements for telehealth in palliative care patients with advanced cancer.DesignThis was designed as a systematic review and meta-analysis with narrative synthesis (registered; CRD42024581786). The effects on patients' quality of life, symptom burden, and depression were analyzed using a rando

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… Telehospice for cancer patients discharged from a tertiary care hospital in Western Kenya . J Pain Symptom Manag 2023 ; 65 ( 5 ): 378 – 387 . 10.1016/j.jpainsymman.2023.01.027 PMC10106447 36773732 47 Formica V Fossile E Pellegrino R , et al . The Medical Care Continuity (MCC) project. …

The effectiveness of school-based family asthma educational programs on the quality of life and number of asthma exacerbations of children aged five to 18 years diagnosed with asthma: a systematic review protocol.

REVIEW OBJECTIVE: The objective of this review is to identify the best available quantitative evidence related to the effectiveness of schoo … from the Ivory Coast, Costa Rica and Wales have higher asthma prevalence compared to children from Kenya, Brazil and England respectively. Indigenous Australians, Aboriginal and Torres Strait Islander Australian children have a higher prevalence of asthma compared to non-Indigenous Australian children. The international prevalence of asthma prompted go …

Medicinal Plants with Anti-Leukemic Effects: A Review.

Leukemia is a leukocyte cancer that is characterized by anarchic growth of immature immune cells in the bone marrow, blood and spleen. There are many forms of leukemia, and the best course of therapy and the chance of a patient's survival depend on the type of leukemic disease. Different forms of drugs have been used to treat leukemia. Due to the adverse effects associated with such therapies and drug resistance, the search for safer and more effective drugs remains one of the most challenging areas of research. Thus, new therapeutic approaches are important to improving outcomes. Almost half

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… Tithonia diversifolia as a green manure for soil fertility improvement in western Kenya: A review Agrofor. Syst. 2000 49 201 221 10.1023/A:1006339025728 126. Oliveira F. Andrade-Neto V. Krettli A. Brandão M. …

Multidrug-Resistant Bacteria in Immunocompromised Patients.

The increasing incidence of antibiotic resistance in bacteria is a major problem in terms of therapeutic options, especially in immunocompromised patients, such as patients from intensive care units (ICUs), HIV-positive patients, patients with malignancies or transplant patients. Commensal bacteria, especially anaerobes, serve to maintain microbial stability by preventing overpopulation with pathogenic bacteria. In immunocompromised patients, microbiota imbalance caused by antibiotic therapy and decreased host immunity favors intestinal overpopulation with pathogenic species, leading to increa

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… A study from Kenya regarding bacterial infections of 162 ICU patients showed that 90 patients (55.6%) had bacterial infections with GNB, the most common infections being urinary tract infections, wound infections and lower respiratory tract infections. …

Reporting of surrogate endpoints in randomised controlled trial protocols (SPIRIT-Surrogate): extension checklist with explanation and elaboration.

Randomised controlled trials often use surrogate endpoints to substitute for a target outcome (an outcome of direct interest and relevance to trial participants, clinicians, and other stakeholders—eg, all cause mortality) to improve efficiency (through shortened duration of follow-up, reduced sample size, and lower research costs), and for ethical or practical reasons. However, their use has a fundamental limitation in terms of uncertainty of the intervention effect on the target outcome and limited information on potential intervention harms. There have been increasing calls for improved repo

Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration.

Randomised controlled trials commonly use surrogate endpoints to substitute for a target outcome (outcome of direct interest and relevance to trial participants, clinicians, and other stakeholders—eg, all cause mortality) to improve their efficiency (through shorter trial duration, reduced sample size, and thus lower research costs), or for ethical or practical reasons. But reliance on surrogate endpoints can increase the uncertainty of an intervention’s treatment effect and potential failure to provide adequate information on intervention harms, which has led to calls for improved reporting o

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… Consent and Community Engagement in Diverse Research Contexts: Reviewing and Developing Research and Practice: Participants in the Community Engagement and Consent Workshop, Kilifi, Kenya, March 2011 . J Empir Res Hum Res Ethics 2013 ; 8 : 1 - 18 . 10.1525/jer.2013.8.4.1 . …

The 11th NORDIC NUTRITION CONFERENCE NNC2016.

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Haematological Diseases in the Tropics

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Ход работы сессии 29th Европейский конгресс педиатрии.

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… Czech Republic; 6 Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Türkiye; 7 Department of Paediatric Rheumatology, Great Ormond Street Hospital, London, United Kingdom; 8 Department of Paediatric Rheumatology, Aga Khan University Hospital, Nairobi, Kenya …