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Preseason Baseline Neurocognitive Performances and Symptom Reporting on Immediate Post-Concussion Assessment and Cognitive Testing: A Comparison of Adolescent Student-Athletes Tested in Spanish and English.

CONTEXT: Student-athletes are commonly administered the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) battery at preseason baseline and postconcussion. The ImPACT is available in many languages, but few researchers have examined differences in cognitive performances and symptom ratings based on the language of administration. OBJECTIVE: To examine differences in ImPACT neurocognitive composites and symptom reporting at preseason baseline testing between student-athletes who completed ImPACT in Spanish versus English. DESIGN: Cross-sectional study. SETTING: Preseason ba

Is the endorsement of the Attention Deficit Hyperactivity Disorder symptom criteria ratings influenced by informant assessment, gender, age, and co-occurring disorders? A measurement invariance study.

OBJECTIVES: This study aims to ascertain whether the differences of prevalence and severity of attention deficit hyperactivity disorder (ADHD) are true or whether children are perceived and rated differently by parent and teacher informant assessments (INFAs) according to gender, age, and co-occurring disorders, even at equal levels of latent ADHD traits. METHODS: Use of latent trait models (for binary responses) to evaluate measurement invariance in children with ADHD and their siblings from the International Multicenter ADHD Gene data. RESULTS: Substantial measurement noninvariance between

Symptom prevalence, severity and palliative care needs assessment using the Palliative Outcome Scale: a cross-sectional study of patients with Parkinson's disease and related neurological conditions.

BACKGROUND: Palliative care is rarely being offered to patients with Parkinson's disease. AIM: To assess symptom prevalence, severity and palliative care needs in advanced stages of Parkinsonism. DESIGN: A cross-sectional survey using a palliative care assessment tool, the Palliative Outcome Scale was administered to patients. SETTING/PARTICIPANTS: Eight-two patients with a diagnosis of idiopathic Parkinson's disease, multiple systems atrophy or progressive supranuclear palsy were included in the study. RESULTS: Their mean age and disease stages 3-5 Hoehn and Yahr were 67 years and 4.1, re

[Validation of the new version of the minimal documentation system (MIDOS) for patients in palliative care : the German version of the edmonton symptom assessment scale (ESAS)].

BACKGROUND: repeated self-assessment of symptoms and problems of patients is required for quality assurance in palliative care. In Germany, the Minimal Documentation System (MIDOS) has been designed specifically for palliative care patients. To adapt MIDOS as a German version of the Edmonton Symptom Assessment Scale (ESAS) a revised version of MIDOS(2) has now been validated. Two original items on average and highest pain intensity (11-step NRS) were replaced by one item on pain intensity on a 4-step VRS and the assessment of vomitus, lack of appetite and depressive mood were added to the asse…

Development and Preliminary Testing of the Withdrawal Assessment Tool-Alpha 2 Agonist: An Assessment Instrument for Monitoring Iatrogenic Withdrawal Symptoms in Children Receiving an Alpha-2 Agonist.

OBJECTIVES: To develop and conduct preliminary testing of the Withdrawal Assessment Tool-Alpha 2 Agonist (WAT-A2A) to monitor dexmedetomidine and clonidine withdrawal symptoms in acutely ill children. DESIGN: Three-phase instrument development study. Phase 1: retrospective chart review of symptoms exhibited by children with documented dexmedetomidine withdrawal; phase 2: WAT-A2A instrument construction based on phase 1 data; and phase 3: prospective testing of the WAT-A2A in children weaning from alpha 2 agonists (A2As). SETTING: Academic free-standing children's hospital. PATIENTS: Acutely

Comparative assessment of reported symptoms of influenza, respiratory syncytial virus, and human metapneumovirus infection during hospitalization and post-discharge assessed by Respiratory Intensity and Impact Questionnaire.

BACKGROUND: The hospitalized acute respiratory tract infection (HARTI) study used the Respiratory Intensity and Impact Questionnaire (RiiQ™) Symptom Scale, derived from FluiiQ™, to assess and compare the burden of respiratory infection symptoms for patients with influenza, respiratory syncytial virus (RSV), and human metapneumovirus (hMPV) infection, with or without core risk factors (CRF) (age ≥65; chronic heart, renal, obstructive pulmonary disease; asthma). METHODS: This was a prospective cohort study in adult patients hospitalized with acute respiratory tract infection (40 centers, 12 cou

Characterizing Pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Symptom Burden, Functional Impairment, and Comparison With Adults in the Multi-Site Clinical Assessment of ME/CFS (MCAM) Study.

OBJECTIVES: To characterize the clinical, functional, and educational characteristics of adolescents with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and compare selected illness domains with adults in the Multi-Site Clinical Assessment of ME/CFS (MCAM) study. STUDY DESIGN: Baseline cross-sectional data from adolescents aged 10-17 years enrolled in MCAM were analyzed. Standardized measures included the Short Form-36 (SF-36v2), CDC Symptom Inventory (CDC-SI), Multidimensional Fatigue Inventory (MFI-20), and selected domains of the DePaul Questionnaire. Descriptive statistics ch

Validation of the Functional Assessment of Cancer Therapy - Immune Checkpoint Modulator 17-Item Symptom Index (FACT-ICM-17) to facilitate implementation in research and clinical care.

BACKGROUND: Immune checkpoint modulators (ICMs) have revolutionized cancer treatment but have unique immune-related adverse events (irAEs). The aim of this study was to develop and validate a brief measure of the most common, distressing, and diagnostically useful symptomatic irAEs. METHODS: Items were generated to assess symptomatic irAEs through a multistep process of (1) literature review and iterative expert input and (2) qualitative interviews of patients, caregivers, and clinicians regarding ICM-related irAEs and quality of life (QOL) impacts. An initial item set was administered across

Comparison of recognition of symptom burden in MPN between patient- and physician-reported assessment - an intraindividual analysis by the German Study Group for MPN (GSG-MPN).

Myeloproliferative neoplasms (MPN) are associated with a variety of symptoms that severely impact patients' quality of life and ability to perform daily activities. Recent studies showed differences in the perception of physician- versus patient-reported symptom burden. However, studies directly comparing patient- and physician-reported ratings are lacking. Here, a retrospective analysis on symptom burden of 3979 MPN patients of the Bioregistry of the German Study Group for MPN was conducted to intra-individually compare physician and patient reports collected at the same time. Cohen's kappa w

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… We found only one study with data on simultaneous patient-physician symptom assessment in MPN patients, which similarly showed that patients reported higher symptom presence than physicians [ 9 ]. … The MPN Landmark survey also found that only 26% of participating physicians used a validated symptom assessment form, with nearly half using their own rating methods [ 3 ]. …

Assessment of the quality of life of patients with advanced and end-stage cancer or serious infections with a symptom-based or an impact-based instrument.

In 1992 a project was started in which home care technology was made available to patients with cancer or serious infections. Primary care providers were trained and supported to administer parenteral drugs and fluids in the home setting. Between 1992 and 1995 we applied the Rotterdam Symptom Checklist (RSCL) and the Sickness Impact Profile (SIP) as questionnaires for quality of life (QoL) assessment in a group of 112 hospitalized patients who were prepared to receive further treatment at home. Scores on the RSCL revealed a high level of symptomatology in both the physical and the psychologica

Optimizing brief, focused assessment of priority symptoms and concerns in recurrent and/or metastatic squamous cell carcinoma of the head and neck: Content validation of the Functional Assessment of Cancer Therapy/National Comprehensive Cancer Network Head and Neck Symptom Index-10 (FHNSI-10).

BACKGROUND AND AIMS: Patients with recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) experience vast disease and treatment burdens. Brief, focused instruments are needed to assess patient-reported priority symptoms and concerns as targeted outcome assessments for use in clinical research. Although the instrument was developed based on expert and patient input and is psychometrically valid, the Functional Assessment of Cancer Therapy (FACT)/National Comprehensive Cancer Network (NCCN) Head and Neck Symptom Index-10 (FHNSI-10) has yet to undergo content valid

Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International Index of Erectile Function-5 questionnaires.

OBJECTIVE: The aim of this study is to assess the association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) using the Core Lower Urinary Tract Symptom Score (CLSS) and the International Index of Erectile Dysfunction (IIEF)-5 questionnaires. METHODS: A total of 220 consecutive treatment-naive men completed the International Prostate Symptom Score (IPSS), CLSS, and IIEF-5 questionnaires. The clinical diagnoses were benign prostate hyperplasia (BPH, n=58), prostatic cancer (n=51), prostatitis (n=28), overactive bladder wet (OAB wet, n=16), other diagnoses (n=39), and

Assessment of mental and behavioural non-motor symptoms of Parkinson's Disease using Artificial Intelligence (AI): a systematic review.

BACKGROUND: Parkinson's disease is a progressive neurodegenerative disorder with both motor and non-motor symptoms. Mental and behavioural non-motor symptoms such as cognitive impairment, sleep disturbances, depression, and anxiety greatly affect quality of life but remain difficult to assess with traditional tools. Artificial intelligence has shown potential in healthcare, yet its role in evaluating these symptoms in Parkinson's disease remains under-reviewed. This systematic review aims to evaluate the performance of artificial intelligence tools in diagnosing, assessing, and managing these

Musculoskeletal symptoms among teleworkers assessed using validated tools: a systematic review and single-arm meta-analysis.

BACKGROUND: Work-related musculoskeletal disorders are common in teleworkers, but reported prevalence rates are inconsistent. This study aimed to estimate the pooled prevalence of musculoskeletal symptoms and to quantify ergonomic risk in teleworkers through single-arm meta-analysis. METHODS: Two reviewers searched PubMed, Scopus, Web of Science, and EBSCO from database inception to March 19, 2026 for observational studies reporting musculoskeletal symptoms or ergonomic risk in teleworkers assessed using validated instruments. A random-effects single-arm meta-analysis was performed to calcula

Validation of a french assessment of prolonged grief (PG-13-R): Age-by-gender differences in prolonged grief symptoms.

Prolonged Grief Disorder (PGD) is a persistent form of grief associated with substantial functional impairment. The PG-13-Revised (PG-13-R), aligned with DSM-5-TR criteria, has not been validated in French. This study evaluated its psychometric properties in bereaved adults (N = 1,066; ≥12 months post-loss; 30-day retest n = 270). Following translation, the PG-13-R demonstrated a unidimensional structure, excellent internal consistency (ω=.92), strong test-retest reliability (ρ=.815, p<.001), and expected associations with symptoms of pathological grief (TGI-SR), post-traumatic stress (PCL-5),

Relationship between depression, neuropsychiatric symptoms and cognitive profiles of the elderly in India: An assessment using the ICMR-MUDRA toolbox.

India's aging population faces escalating cognitive decline and neuropsychiatric challenges. This cross-sectional study examined relationships between geriatric depression, neuropsychiatric symptoms and cognitive performance among 1,013 community-dwelling elderly participants (≥60 years) in Gorakhpur using the ICMR-MUDRA Toolbox. Multistage random sampling was employed. Depression was assessed using GDS-30, and neuropsychiatric symptoms were assessed using NPI-Brief. It was observed that geriatric depression was present in 63.3% of participants, while neuropsychiatric symptoms affected 78.5%,

Computerized assessments of emotional expression and emotional reactivity predict negative symptoms in individuals at clinical high-risk for psychosis.

BACKGROUND: Negative symptoms are a core feature of psychosis and a strong predictor of functional outcome, yet they remain difficult to assess due to conceptual and methodological challenges. Although abnormalities in emotional expressivity and emotional reactivity are documented in individuals at clinical high-risk (CHR) for psychosis, these domains are typically examined independently, and their relationship remains unclear. METHODS: Facial expressions were quantified using automated facial analysis (FaceReader) during clinical interviews in 101 CHR individuals and 41 healthy controls (HCs

Guidance for the assessment of the dietary intake and gastrointestinal or nutrition impact symptoms etiologic criterion of GLIM: A modified-Delphi study.

The GLIM malnutrition diagnostic framework includes the etiologic criterion for reduced dietary intake or assimilation (i.e., digestion or absorption). This criterion required further specification to support consistent use in clinical practice. Three rounds of a modified Delphi was undertaken to develop consensus on guidance to support identification of this criterion. A working group (n = 11) developed surveys iteratively. Invited global experts with diverse disciplines and practice contexts (n = 30) fully completed surveys; consensus was determined at 75% agreement. Three surveys and rounds