Результаты поиска

[The significance of mechanical factors in the development of spondylolysis. Experimental studies (author's transl)].

The cause of spondylolysis is a controversial subject. A variety of experiments were conducted at the University Orthopedic Clinic in Frankfurt am Main to determine the significance of mechanical factors. Experiments on dogs whose lumbosacral joints were forced into lordosis by a specially developed instrumentarium did not prove that processes tantamount to fatigue fracture occur in the pars interarticularis. Two series of experiments were carried out on the lumbar vertebral columns of adults, stretch measuring strips being attached to the pars interarticularis. The forces acting on the L5 par…

Leading through strain and satisfaction: A mixed methods study of principal well-being through the dual-factor and job demands-resources frameworks.

Guided by the job demands-resources model and dual-factor model of mental health, this study used a mixed method survey to examine principals' experiences with job demands, resources, and their compassion fatigue and satisfaction in the context of postpandemic recovery based on a survey study conducted among 247 principals in California. Quantitative and qualitative analyses on survey responses suggested that staffing shortages, the spillover effect of COVID-19, the school community's needs, and workload were identified as top stressors. Regression and path analyses demonstrated a significant …

Characteristics and influencing factors of sleep disturbance in breast cancer patients: a cross-sectional study.

BACKGROUND: With prolonged survival of breast cancer patients, symptom management is increasingly pivotal. Sleep disturbance, a prevalent and persistent quality-of-life-impairing symptom, remains incompletely elucidated, thus this study aims to clarify its clinical characteristics and influencing factors. METHODS: A total of 150 breast cancer patients were recruited. Sleep disturbance was assessed using the Pittsburgh Sleep Quality Index (PSQI). Pain was evaluated with the Visual Analogue Scale (VAS), fatigue via the Revised Piper Fatigue Scale (PFS-R), and emotional status through the Hospit…

The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension.

The aim of the study was to investigate the effect of MOTS-c on the key functional alterations in the rat soleus muscle during 7-day unloading - the transformation of slow fibers into fast ones, atrophy and increased fatigue. We daily intraperitoneally injected male Wistar rats with a short mitochondrial peptide MOTS-c during 7-day unloading of their hind limbs. After the end of the experiment, we conducted an ex vivo fatigue test of soleus muscle and showed that the MOTS-c administration prevents increased fatigue during 7-day hind limb unloading. Also, using immunohistochemical analysis, we …

Гейт Кинематика, оцененная Виконом, и качество корреляции жизни у пациентов с множественным склерозом: перекрестное исследование.

Множественный склероз — это воспалительное и нейродегенеративное заболевание, которое приводит к моторным, когнитивным и сенсорным расстройствам, серьезно влияющим на ходьбу и качество жизни. Цель этого исследования состояла в анализе взаимосвязи между качеством жизни и кинематическими параметрами ходьбы у лиц с множественным склерозом, а также в оценке влияния усталости, равновесия и когнитивных характеристик на различные аспекты качества жизни. Было проведено перекрестное наблюдение с 32 пациентами, у которых диагностирован множественный склероз с увеличением шкалы инвалидности в размере ≤5,

Совпадение в аннотации оригинала
Multiple sclerosis is an inflammatory and neurodegenerative disease that leads to motor, cognitive, and sensory impairments, significantly a … walking parameters in individuals with multiple sclerosis, as well as to evaluate the influence of fatigue, balance, and cognitive performance on different aspects of quality of life. A cross-sectional observational study was conducted with 32 patients diagnosed with multiple sclerosis with Expanded Disability Status Scale scores of ≤5.5. Quality of life …

Факторы, связанные с саморегистрацией способностей к труду у людей с множественным склерозом в Швеции.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Индекс способностей к труду (ИПТ) является инструментом, измеряющим способность к труду при проведении обследований на рабочем месте и медицинских обследований в области гигиены труда и исследований. Он используется в различных группах населения. Но исследования ограничены среди людей с множественным склерозом (PwMS). ЦЕЛЬ: Определение факторов, связанных с производственными способностями, среди ПТМС в Швеции. МЕТОДЫ: В анализ было включено в общей сложности 4103 ПВМС, которые ответили на вопросы обследования на базе Интернета. Способность к труду оценивалась с использов

Совпадение в аннотации оригинала
BACKGROUND: Work ability index (WAI) is an instrument that measures work ability in workplace surveys and health examinations in occupationa … ll mean WAS was 6.9 (standard deviation = 2.8). Health-related quality of life (R-squared = 31.6%), fatigue (28.3%), occupation (22.6%), and expanded disability status scale (EDSS) score (18.1%), explained the highest proportions of variation in WAS, individually. In the adjusted model, occupation, EDSS score, and fatigue had the strongest associations wi …

Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study.

BACKGROUND: Osimertinib is regarded as a promising third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) for advanced non-squamous non-small cell lung cancer (NSCLC) patients who developed T790M. However the adverse effects, primarily fatigue, remain an overwhelming deficiency of Osimertinib, hindering it from achieving adequate clinical efficacy for such NSCLC. Ganoderma lucidum has been used for thousands of years in China to combat fatigue, while Ganoderma Lucidum spores powder (GLSP) is the main active ingredient. The aim of this study is to investigate w…

Spring-Mass Characteristics in Runners Before and After a 56-km Road Ultramarathon.

Ultramarathons are a unique model to study the effects of systemic fatigue in athletes. This investigation applied the spring-mass template to study runners before and 2 days after a road ultramarathon to characterize the effects of fatigue on systemic gait patterns. Overground kinetics were captured 7 days before and 2 days after the event in 14 runners. Traditional kinetic and spring-mass parameters were calculated, along with nonlinear regression-derived parameters and spring-mass model fit metrics. After the ultramarathon, vertical force magnitudes and loading rates were unchanged, but imp…

Relationship between Sleep Quality and Shoulder Disorders in People with Stroke.

Background and objective: The primary aim of the study was to investigate the relationship between sleep quality (SQ) and shoulder disorders in people after a stroke. The secondary aim was to explore the relationship between SQ and stroke outcomes, including the impact of stroke, fatigue, and quality of life (QOL). Material and Methods: A sample of 94 stroke patients was included. The Pittsburgh Sleep Quality Index (PSQI) was used to assess SQ, whereas the Shoulder Pain and Disability Index (SPADI) was utilized to assess shoulder pain and disability. The Stroke Impact Scale 16, the Modified Fa…

Perceived Cognitive Function in People With Systemic Sclerosis: Associations With Symptoms and Daily Life Functioning.

OBJECTIVE: Perceived cognitive dysfunction is prevalent in patients with systemic sclerosis (SSc) but not well understood. This study aimed … s with SSc perceived mild-to-severe cognitive dysfunction. Being on work disability and having more fatigue were both significantly associated with perceived cognitive dysfunction. When examining the contributions of cognition and other symptoms to functional measures, self-reported cognition became nonsignificant after fatigue and pain were entered into …

Health-related quality of life in patients with neuroendocrine neoplasms: a two-wave longitudinal study.

PURPOSE: Scientific knowledge on health-related quality of life (HRQoL) in patients with neuroendocrine neoplasm (NEN) is still limited and … ciated to the absence of distant metastases, while the presence of metastases with higher levels of fatigue, diarrhea, and financial difficulties. Higher levels of resilience are still associated with better GH and lower levels of fatigue, diarrhea, and financial difficulties, but no longer with constipation. Furthermore, patients with gastroenteropancrea …

The effects of operating height and the passage of time on the end-point performance of fine manipulative tasks that require high accuracy.

Sustained shoulder abduction, which results from an inappropriate worktable height or tool shape and long task hours, leads to an accumulation of muscle fatigue and subsequent work-related injuries in workers. It can be alleviated by controlling the table height or ergonomic tool design, but workers who are doing some types of work that require a discomfortable posture, such as minimally invasive surgery, cannot avoid these situations. Loads to the shoulder joint or muscles result in several problems, such as muscle fatigue, deterioration of proprioception or changing movement strategies of th…

Cardiovascular Autonomic Regulation, ETCO2 and the Heart Rate Response to the Tilt Table Test in Patients with Orthostatic Intolerance.

Chronic orthostatic intolerance (COI) is defined by changes in heart rate (HR), blood pressure (BP), respiration, symptoms of cerebral hypop … autonomic control, the orthostatic HR response, EtCO2 and the severity of orthostatic symptoms and fatigue in patients referred for evaluation of COI. Patients (N = 108) performed standardized testing protocol of the Autonomic Reflex Screen and completed the Composite Autonomic Symptom Score (COMPASS-31) and the Fatigue Severity Scale (FSS). Greater seve …

Pain as a significant symptom in patients with periodic paralysis-A cross-sectional survey.

INTRODUCTION: Periodic paralysis (PP) is thought to be limited to episodes of muscle weakness, but there are reports of fibromyalgia-like pain in PP. We aimed to evaluate pain and comorbid sleep, fatigue, and mood disorders in PP patients. METHODS: We administered a cross-sectional survey to PP patients at the 2019 Periodic Paralysis Conference. The survey consisted of the Brief Pain Inventory, Widespread Pain Index, Pittsburgh Sleep Quality Index, Modified Fatigue Impact Scale, and ten-question Center for Epidemiologic Studies Depression Scale (CESD-10). Descriptive statistics for PP patient…

Identification of physical and psychosocial problems based on symptoms in patients with Behçet's disease.

The purpose of this study was to use the International Classification of Functioning, Disability and Health (ICF) to identify physical and p … number of problem categories was significantly greater in patients with BD with eye involvement and fatigue (eye involvement, 25.7 categories; fatigue, 25.2 categories; both P < 0.001). Specifically, patients with eye involvement had more difficulties with problems in daily life, such as writing (odds ratio 4.2), understanding such nonverbal messages as g …

Changes in joint, muscle, and tendon stiffness following repeated hopping exercise.

The purpose of this study was to elucidate the mechanisms of decline in joint stiffness after repeated stretch-shortening cycle exercises according to changes in both muscle-tendon properties and neuromuscular activities. Eleven males performed fatigue task (5 sets of 50 hopping). Ankle joint stiffness and electromyographic activities (mEMG) of plantar flexor and tibial anterior muscles during drop jump were measured before and after fatigue task. Active muscle stiffness with (100 deg·sec-1 ) and without (250 deg·sec-1 ) stretch reflex were calculated according to changes in estimated muscle f…

The hybrid assistive limb (HAL) for Care Support successfully reduced lumbar load in repetitive lifting movements.

Work-related low back pain is a serious socioeconomic problem. This study examined whether HAL for Care Support, which is a newly developed wearable robot, would decrease lumbar fatigue and improve lifting performance during repetitive lifting movements. Eighteen healthy volunteers (11 men, 7 women) performed repetitive stoop lifting movements of a cardboard box weighing 12 kg as many times as possible. The first lifting trial was executed without HAL for Care Support, and the second was with it. We evaluated the VAS of lumbar fatigue as the lumbar load and the number of lifts and the lifting …

The hybrid assisted limb (HAL) for Care Support, a motion assisting robot providing exoskeletal lumbar support, can potentially reduce lumbar load in repetitive snow-shoveling movements.

An excessive lumbar load with snow-shoveling is a serious problem in snowfall areas. Various exoskeletal robots have been developed to reduce lumbar load in lifting work. However, few studies have reported the attempt of snow-shoveling work using exoskeletal robots. The purpose of the present study was to test the hypothesis that the HAL for Care Support robot would reduce lumbar load in repetitive snow-shoveling movements. Nine healthy male volunteers performed repetitive snow-shoveling movements outdoors in a snowfall area for as long as possible until they were fatigued. The snow-shoveling …

Reliability of contractile properties of the knee extensor muscles in individuals with post-polio syndrome.

OBJECTIVE: To assess the reliability of contractile properties of the knee extensor muscles in 23 individuals with post-polio syndrome (PPS) and 18 age-matched healthy individuals. METHODS: Contractile properties of the knee extensors were assessed from repeated electrically evoked contractions on 2 separate days, with the use of a fixed dynamometer. Reliability was determined for fatigue resistance, rate of torque development (MRTD), and early and late relaxation time (RT50 and RT25), using the intraclass correlation coefficient (ICC) and standard error of measurement (SEM, expressed as % of…

Optical flow and driver's kinematics analysis for state of alert sensing.

Road accident statistics from different countries show that a significant number of accidents occur due to driver's fatigue and lack of awareness to traffic conditions. In particular, about 60% of the accidents in which long haul truck and bus drivers are involved are attributed to drowsiness and fatigue. It is thus fundamental to improve non-invasive systems for sensing a driver's state of alert. One of the main challenges to correctly resolve the state of alert is measuring the percentage of eyelid closure over time (PERCLOS), despite the driver's head and body movements. In this paper, we p…