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Longitudinal Assessment of Ocular Biomarkers in Individuals With Gulf War Illness Symptoms.

INTRODUCTION: Gulf War illness (GWI) is characterized by a constellation of symptoms, including, but not limited to, diarrhea, fatigue, and memory problems that affect Gulf War veterans. Currently, there are no objective biomarkers for GWI. Previous studies have identified differences in optical coherence tomography (OCT) metrics between individuals with GWI symptoms and those without. However, there are limited data on how these metrics change over time. Therefore, in this current study, we conducted a prospective case-control investigation to determine if OCT metrics show longitudinal change

Leveraging an established neighbourhood-level, open access wastewater monitoring network to address public health priorities: a population-based study.

BACKGROUND: Before the COVID-19 pandemic, the US opioid epidemic triggered a collaborative municipal and academic effort in Tempe, Arizona, which resulted in the world's first open access dashboard featuring neighbourhood-level trends informed by wastewater-based epidemiology (WBE). This study aimed to showcase how wastewater monitoring, once established and accepted by a community, could readily be adapted to respond to newly emerging public health priorities. METHODS: In this population-based study in Greater Tempe, Arizona, an existing opioid monitoring WBE network was modified to track SA

[Epidemiological characteristics of dengue fever in Shenzhen City in 2024].

OBJECTIVE: To investigate the epidemiological characteristics of dengue fever in Shenzhen City in 2024, so as to provide insights into formulation of the preventive and control measures for dengue fever. METHODS: The epidemiological data of dengue cases reported in Shenzhen City in 2024 were extracted from the China Disease Prevention and Control Information System and field epidemiological survey data of dengue fever in Shenzhen City, and the temporal, regional and population distributions of dengue fever cases, source of acquire dengue virus infections, disease diagnosis and treatment and o

Proceedings of the 8th Annual Conference on the Science of Dissemination and Implementation : Washington, DC, USA. 14-15 December 2015.

A1 Introduction to the 8th Annual Conference on the Science of Dissemination and Implementation: Optimizing Personal and Population Health David Chambers, Lisa Simpson D1 Discussion forum: Population health D&I research Felicia Hill-Briggs D2 Discussion forum: Global health D&I research Gila Neta, Cynthia Vinson D3 Discussion forum: Precision medicine and D&I research David Chambers S1 Predictors of community therapists’ use of therapy techniques in a large public mental health system Rinad Beidas, Steven Marcus, Gregory Aarons, Kimberly Hoagwood, Sonja Schoenwald, Arthur Evans, Matthew Hurfor

Early intervention for high-risk smoldering multiple myeloma (SMM).

RATIONALE: Smoldering multiple myeloma (SMM) represents an intermediate stage between monoclonal gammopathy of undetermined significance (MGUS) and active multiple myeloma. Early identification and intervention for people with high-risk SMM may prevent or delay progression to symptomatic disease. Current evidence on the optimal timing and choice of intervention remains controversial, necessitating a systematic evaluation. OBJECTIVES: To evaluate the benefits and harms of different early interventions compared to observation alone or placebo in people with high-risk smoldering multiple myeloma

Clinical and experimental observations with regard to the injection of certain agents (Pregl's Solution) into chronic arthritic joints : J. E. M. Thomson MD (1889-1962). The 14th President of the AAOS 1946.

J.E.M. (Tommy) Thomson was born in Los Angeles, California in 1989, of “pious and scholarly” parents with “evangelistic...interests” [3]. His grandfather had been a missionary bishop in the Methodist Church. He attended Evanston Academy and then Northwestern University. While he began his medical studies at Texas Christian College, he completed his medical education at Rush Medical College in 1915. He took an internship in Chicago, where his mentors reportedly included Drs. Edwin Ryerson (first President of the AAOS), John Ridlon, and Dallas Phemister [3]. In 1916 he began medical practice wit

Investigations of Possible Multistate Outbreaks of Salmonella, Shiga Toxin-Producing Escherichia coli, and Listeria monocytogenes Infections - United States, 2016.

PROBLEM/CONDITION: Salmonella, Shiga toxin-producing Escherichia coli (STEC), and Listeria monocytogenes are the leading causes of multistate foodborne disease outbreaks in the United States. Responding to multistate outbreaks quickly and effectively and applying lessons learned about outbreak sources, modes of transmission, and risk factors for infection can prevent additional outbreak-associated illnesses and save lives. This report summarizes the investigations of multistate outbreaks and possible outbreaks of Salmonella, STEC, and L. monocytogenes infections coordinated by CDC during the 2

On the Occasion of the 80th Anniversary of the Faculty of Medicine of Charles University in Hradec Králové.

Last autumn we commemorated the 80th anniversary of the founding of the Faculty of Medicine of Charles University in Hradec Králové. A number of events were held and several publications were released, including a special issue of the Časopis lékařů českých entirely dedicated to this anniversary and to the faculty. At the ceremonial assembly of the academic community on 8 October 2025, the dean of the faculty, Professor Manďák, delivered an extensive speech in which he clearly described the historical circumstances of the faculty's foundation, its beginnings, development, and growth through va

[Expert consensus on optimizing the multidisciplinary clinical pathways and management models for pulmonary function testing].

The promotion and application of pulmonary function tests (PFTs) in China have achieved preliminary success;however, numerous deficiencies persist in multidisciplinary PFT clinical application pathways and management. Current challenges remain in identifing target population, implementing pathways within and outside medical institutions, allocating hardware, training personnel, managing information, and assessing performance.The consensus aims to optimize multidisciplinary clinical pathways and management models for PFTs by leveraging information technology and strengthening organizational coo

Healthcare workers' perceptions and experiences of communicating with people over 50 years of age about vaccination: a qualitative evidence synthesis.

BACKGROUND: Infectious diseases are a major cause of illness and death among older adults. Vaccines can prevent infectious diseases, including against seasonal influenza, pneumococcal diseases, herpes zoster and COVID-19. However, the uptake of vaccination among older adults varies across settings and groups. Communication with healthcare workers can play an important role in older people's decisions to vaccinate. To support an informed decision about vaccination, healthcare workers should be able to identify the older person's knowledge gaps, needs and concerns. They should also be able to sh

[Italian Cystic Fibrosis Registry (ICFR). Report 2021-2022].

INTRODUCTION: Italian Cystic Fibrosis Registry (ICFR) collects data of patients with cystic fibrosis (CF) through the collaboration with Italian CF referral and support Centres (Italian law 548/93). It aims at analysing medium and long-term clinical and epidemiological trends, identifying healthcare needs at regional and national levels, contributing to healthcare programmes, and resource allocation. Italian data are also compared at international level through the collaboration with the European CF Registry for sharing epidemiological data on general aspects like CF epidemiology and specific

Contributing Factors of Foodborne Illness Outbreaks - National Outbreak Reporting System, United States, 2014-2022.

PROBLEM/CONDITION: Approximately 800 foodborne illness outbreaks occur in the United States each year. These outbreaks include approximately 15,000 illnesses, 800 hospitalizations, and 20 deaths. Although illnesses from outbreaks account for a small portion of all foodborne illnesses, outbreak investigations reveal how these illnesses originate by offering crucial data through epidemiologic, environmental health, and laboratory analyses and aid in outbreak mitigation and prevention. PERIOD COVERED: 2014-2022. DESCRIPTION OF SYSTEM: The Foodborne Disease Outbreak Surveillance System (FDOSS),

International guidelines for groin hernia management.

INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the Euro

Использование ресурсов здравоохранения и связанные с этим расходы в течение первого периода 5 Годы после диагностирования и в конце жизни: Общенациональное кохортное исследование пациентов с множественной миеломой в Финляндии.

Как ожидается, в связи со старением населения возрастет бремя, связанное с лечением пациентов с множественной миеломой (ММ). Таким образом, политикам и врачам необходимо целостное представление об использовании ресурсов здравоохранения (ГХРУ) и расходах, связанных с ММ и его лечением для принятия обоснованных решений. Вместе с тем в Финляндии практически отсутствует общенациональная информация о ГКРУ и расходах, связанных с ММ. Цель этого исследования состояла в том, чтобы определить использование ресурсов здравоохранения, модели использования услуг и связанные с этим расходы финских пациентов

Оказание высококачественной комплексной помощи в области склероза в Германии: проблемы и региональные модели.

Множественная склерозовая (МС) помощь в Германии вступила в стадию, когда терапевтический прогресс все больше сдерживается возможностями родовспоможения. Более ранняя диагностика, более широкий доступ к высокоэффективным методам лечения заболеваний (ДМТ) и более совершенные стратегии мониторинга расширили возможности для достижения благоприятных долгосрочных результатов. В то же время эти достижения усилили потребность в специализированных экспертных знаниях, инфильтрации и инфраструктуре мониторинга, оперативном доступе к изображениям, структурированных процедурах обеспечения безопасности и м

Shared-Care in Complex Malignant Hematology: An Integrative Review Using the RE-AIM Evaluation Framework.

Complex malignant hematology (CMH) shared-care programs have been established to support patients with access to care closer to home. This integrative review examined what is known about CMH shared-care using the RE-AIM evaluation framework. We searched five electronic databases for articles published until 16 January 2024. Articles were included if they were qualitative or quantitative studies, reviews or discussion papers, and reported on an experience with shared-care (defined as a reciprocal, ongoing patient-sharing relationship between a specialist centre and community hospital) for patie

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… AND care) OR co-management OR (care AND coordination) OR hospital shared services (meSH) OR (hospital AND (shar? OR sharing?) …

Препятствия и факторы, способствующие реформированию системы здравоохранения.

ВВЕДЕНИЕ: Системы здравоохранения во всем мире сталкиваются с растущим давлением, обусловленным растущим бременем неинфекционных заболеваний и старением населения, а также хронической нехваткой рабочей силы, инфраструктурными ограничениями и структурными дисгармониями между моделями ухода, предназначенными для лечения острых заболеваний, и долгосрочными потребностями сложных пациентов. Многие страны предпринимают комплексные усилия по преобразованию, включая перенос ухода ближе к дому, улучшение раннего выявления заболеваний и решение проблем, связанных с рабочей силой. Цель этого исследования

Factors related to the change in Swiss inpatient costs by disease: a 6-factor decomposition.

There is currently little systematic knowledge about the contribution of different factors to the increase in health care spending in high-income countries such as Switzerland. The aim of this paper is to decompose inpatient care costs in the Swiss canton of Zurich by 100 diseases and 42 age/sex groups and to assess the contribution of six factors to the change in aggregate costs between 2013 and 2017. These six factors are population size, age and sex structure, inpatient treated prevalence, utilization in terms of stays per patient, length of stay per case, and costs per treatment day. Using

Customized Marketing Strategies for Cancer Immunocyte Therapy Based on its Distinctive Attributes.

Cancer constitutes a persistent global health challenge, and immunocyte therapy has emerged as one approach in oncological care. This narrative review aimed to systematically analyze, synthesize, and critically interpret the therapeutic characteristics, advantages, market landscape, and current access barriers of cancer immunocyte therapy, based on thematic clustering and cross‑study integration of clinical evidence, market data, and industry reports. Immunocyte therapy exhibits distinctive features including personalization, long‑term immune memory, and observed efficacy in refractory maligna

Stakeholder perspectives and requirements to guide the development of digital technology for palliative cancer services: a multi-country, cross-sectional, qualitative study in Nigeria, Uganda and Zimbabwe.

IntroductionCoverage of palliative care in low and middle-income countries is very limited, and global projections suggest large increases in need. Novel approaches are needed to achieve the palliative care goals of Universal Health Coverage. This study aimed to identify stakeholders' data and information needs and the role of digital technologies to improve access to and delivery of palliative care for people with advanced cancer in Nigeria, Uganda and Zimbabwe.MethodsWe conducted a multi-country cross-sectional qualitative study in sub-Saharan Africa. In-depth qualitative stakeholder intervi