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Social Factors Influencing Decision-Making in Intracerebral Haemorrhage: A Survey among Neurology Professionals.

INTRODUCTION: Intracerebral haemorrhage (ICH) is the most severe type of stroke characterized by high morbidity and mortality rates. While prognostic scales aim to predict outcomes based solely on medical information, clinicians' assessments may be influenced by patients' social factors, potentially resulting in inequitable care. METHODS: A cross-sectional study using a vignette-based survey presenting five pairs of fictitious ICH cases (10 total) was distributed to professionals involved in ICH patient care. Each pair included identical medical data and a comparable computed tomography scan.

Education Research: Assessing the Current State of Telestroke Exposure in Vascular Neurology Fellowship.

BACKGROUND AND OBJECTIVES: Telestroke is now a core component of acute stroke care, yet how fellows are trained to deliver care in this setting remains variable. With telestroke incorporated into Accreditation Council for Graduate Medical Education (ACGME) milestones, there is a need to better understand current training practices and gaps. The objective of this study was to evaluate telestroke training across vascular neurology (VN) fellowship programs in the United States and identify barriers to fellow participation. METHODS: We conducted a national survey of VN fellowship program director…

Child Neurology: Transient Global Amnesia Precipitated by a Valsalva Maneuver in an Adolescent.

Transient global amnesia (TGA) is a benign clinical syndrome characterized by the sudden onset of anterograde amnesia with preserved consciousness and no focal neurologic deficits, resolving within 24 hours. It predominantly affects middle-aged and older adults and is rarely reported in pediatric populations. In adults, TGA is often preceded by identifiable triggers, including Valsalva maneuvers. We describe a previously healthy, typically developing 16-year-old boy who presented with acute anterograde amnesia after an intentional Valsalva maneuver performed during a school video. He experienc

Case-Based Lessons on Remote Patient Monitoring in Neurology Using Consumer-Grade Wearables.

Consumer-grade wearables offer promising opportunities for remote patient monitoring (RPM) in neurological disorders, yet their clinical application remains uncertain. In this exploratory analysis, we draw on prospective observational trials using smartwatches in patients with multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, and migraine, who were monitored for 6 to 24 months. Through detailed clinical case narratives, we illustrate both the potential and the limitations of RPM in neurology. Wearable-generated data successfully captured early, clinicall…

A needs assessment of palliative care education in neurology residency programs in Brazil.

The importance of integrating palliative care (PC) competencies into the management of neurological diseases is increasingly acknowledged. The National Medical Residency Program Commission (NMRPC) mandates the inclusion of PC in the curricula of neurology residency programs (NRPs).To evaluate the implementation of PC training in NRPs across Brazil and to identify barriers to its effective integration.We conducted a cross-sectional study using an anonymous online survey distributed to all NRP directors in Brazil through the Brazilian Academy of Neurology (BAN). The survey, approved by the insti…

On Neurocardiology Updates: an Interdisciplinary Field at the Intersection of Neurology and Cardiology.

PURPOSE OF REVIEW: This review examines the evolving field of neurocardiology, tracing its development from early homeostatic theories to modern understandings of the bidirectional neural networks that link the heart and brain. We propose an integrative framework to explain neuro-cardiac interactions in health and disease, with a focus on clinical applications and emerging therapies. RECENT FINDINGS: The neuro-cardiac axis comprises hierarchical neural networks, from the intrinsic cardiac nervous system to subcortical and cortical brain regions. This structure underlies a range of clinical sy

Федеративное обучение в области неврологии: обеспечение конфиденциальности данных и искусственного интеллекта для охраны здоровья мозга.

Неврологические расстройства затрагивают сотни миллионов людей во всем мире, однако перевод достижений искусственного интеллекта (АИ) в клиническую практику по-прежнему сопряжен с трудностями из-за разрозненных, чувствительных к конфиденциальности наборов данных. Федеративное обучение (ФЛ) стало многообещающей парадигмой, позволяющей осуществлять совместную типовую подготовку в различных учреждениях без обмена необработанными данными о пациентах. В этом обзоре синтезируются приложения FL в неврологии с 2020 по 2025 год, охватывающие нейроимацию, электрофизиологию и электронные медицинские запи

Совпадение в аннотации оригинала
Neurological disorders affect hundreds of millions globally, yet translating artificial intelligence (AI) advances into clinical practice re … ng across institutions without sharing raw patient data. This review synthesizes FL applications in neurology from 2020 to 2025, spanning neuroimaging, electrophysiology, and electronic health records. We analyze real-world deployments, highlight algorithmic trends, and discuss technical, regulatory, and organizational barriers to clinical translation. Whil …

Absolute quantitation of sympathetic nerve activity using [123I] metaiodobenzylguanidine SPECT-CT in neurology.

BACKGROUND AND PURPOSE: The ability of [123I]metaiodobenzylguanidine (MIBG) sympathetic nerve imaging with three-dimensional (3D) quantitation to clinically diagnose neurological disorders has not been evaluated. This study compared absolute heart counts calculated as mean standardized uptake values (SUVmean) using conventional planar imaging and assessed the contribution of [123I]MIBG single-photon emission computed tomography (SPECT)-CT to the diagnosis of neurological diseases. METHODS: Seventy-two patients with neurological diseases were consecutively assessed using early and delayed [123

Hypnosis therapy for self-esteem in pediatric neurology practice: A pilot exploratory study.

BACKGROUND: A number of pediatric conditions are chronic, such as attention-deficit/hyperactivity disorder (ADHD), idiopathic epilepsies, or anxiety disorder. They all have an impact on self-esteem with consequences on the quality of life. Hypnosis is a therapeutic strategy that consists in putting into trance an individual who becomes receptive to appropriate suggestions. Such an approach is now considered a simple and safe therapy with limited cost. The aim of the present study was to show the feasibility of hypnosis for improving self-esteem in children with the aforementioned conditions.

Biological Mechanism-based Neurology and Psychiatry: A BACE1/2 and Downstream Pathway Model.

In oncology, comprehensive omics and functional enrichment studies have led to an extensive profiling of (epi)genetic and neurobiological al … easing rationale to transfertilize this blueprint to other medical fields, including psychiatry and neurology. In order to illustrate the emerging paradigm shift in neuroscience, we provide a state-of-the-art review of translational studies on the β-site amyloid precursor protein cleaving enzyme (BACE) and its most studied downstream effector, neuregulin, w …

Neighborhood Social Determinants of Health in Patients Seen in Neurology Movement Disorders Clinics.

BACKGROUND AND OBJECTIVES: Chronic health conditions are influenced by social determinants of health (SDH) including neighborhood-linked markers of affluence. We explored whether neighborhood socioeconomic factors differ in people with different types of clinical movement disorders (MDs). METHODS: We conducted a retrospective study of patients seen in MD clinics at our center in 2021. Patient data were linked to the US National Neighborhood Data Archive linked to US census tract data. We evaluated variations in neighborhood socioeconomic factors across 8 different categories of MDs. RESULTS:

Child Neurology: KMT2B-Related Dystonia in a Young Child With Worsening Gait Abnormality.

KMT2B gene-related dystonia (DYT-KMT2B) is a primarily childhood-onset movement disorder that usually starts with lower limb dystonia progressing into generalized dystonia. Our patient described in this study experienced difficulty gaining weight, laryngomalacia, and feeding difficulties during infancy and later developed gait difficulties, frequent falls, and toe walking. Gait assessment revealed prominent bilateral intoeing, intermittent ankle inversion, and extension of left leg. At times, the gait seemed to be spastic. Whole-exome sequencing revealed a novel de novo heterozygous likely pat

Child Neurology: Pathologically Confirmed Thrombotic Microangiopathy Caused by Onasemnogene Abeparvovec Treatment for SMA.

Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy for spinal muscular atrophy (SMA). Although several cases of drug-induced thrombotic microangiopathy due to onasemnogene abeparvovec have been reported, none has been confirmed pathologically. Here, we present renal histopathologic findings of TMA due to onasemnogene abeparvovec. On day 5 after receiving onasemnogene abeparvovec, a 23-month-old girl with SMA type 1 developed thrombocytopenia, microangiopathic hemolytic anemia, liver dysfunction, acute kidney injury, and hypertension. She was diagnosed with TMA and

The Results of Whole Exome Sequencing Performed On Previously Undiagnosed Pediatric Neurology Patients.

OBJECTIVE: Whole exome sequencing (WES) is a new molecular diagnostic test, used in pediatric medicine, especially pediatric neurology. The diagnostic yield of WES is higher than conventional methods. Therefore, this study aimed to assess the diagnostic yield of WES in a pediatric neurology clinic and to report positive results. MATERIALS & METHODS: This retrospective study was performed on patients, presenting to the pediatric neurology clinic of Ghaem Hospital in Mashhad, Iran, between March 2015 and March 2017, with various neurological disabilities and unrevealing workup before WES. The p…

Acute Demyelinating Syndromes: A report of child neurology department of Sfax University Hospital.

INTRODUCTION: The yearly incidence of Acute Demyelinating Syndromes (ADS) in a multiethnic cohort of children published by Langer-Gould and … les; 18 male; SR = 1.33), were collected from the medical records of patients admitted to the child neurology department of Sfax University Hospital between 2008 and 2021 for clinical events with presumed inflammatory origin. Next, patients were categorized as per M. N. Nouri and al. up dated classification for ADS. Finally, characteristics of different ADS …

Clinical Spectrum of Movement Disorders in Neurology Inpatients in a Tertiary Care Centre.

Background  Little data are available on the spectrum of movement disorders in inpatients, particularly those admitted in neurology specialty. This may be related to the fact that patients presenting with movement disorders are usually evaluated from outpatient clinics. Objective  The aim of this study is to provide data on the pattern of movement disorders in neurology inpatients. Materials and Methods  Patients admitted through emergency department or neurology clinic with complaints of movement abnormalities were recruited in this study from October 2019 to September 2020. Cases were subjec…

Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology.

PURPOSE: Hyperintensities are common in neuroimaging scans of patients with mild acute focal neurology. However, their pathogenic role and clinical significance is not well understood. We assessed whether there was an association between hyperintensity score with diagnostic category and clinical assessments/measures. METHODS: One hundred patients (51 ± 12 years; 45:55 women:men), with symptomatology suggestive of short duration ischemia referred for magnetic resonance imaging, were prospectively recruited in NHS Grampian between 2012 and 2014. Hyperintensities were quantified, on T2 and FLAIR…

[Clinical course of myasthenia gravis at the department of neurology in Antananarivo Madagascar].

INTRODUCTION: myasthenia gravis (MG) is a rare disease affecting the neuromuscular junction. It can lead to a life-threatening condition, especially when it is associated with respiratory failure. Full remission is possible with treatment. Our aims are to describe the clinical course of patients with MG with under treatment, in order to further improve management and to implement a database of patients living in Madagascar. METHODS: we conducted a descriptive retrospective study in the Department of Neurology at the Befelatanana Antananarivo University Hospital Center between January 2010 and…