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Iron absorption and distribution in normal and scorbutic guinea pigs.

Ascorbic acid status does not influence iron absorption in normal guinea-pigs. A high tissue ascorbic acid saturation is associated with an increased absorption in iron-loaded animals and in those with a high absorption due to haemolytic anaemia. In all groups the percentage of the absorbed dose retained in the spleen is higher in scorbutic than in normal guinea-pigs.

Carrageenan-induced ulceration of the large intestine in the guinea pig.

A 5% aqueous solution of degraded carrageenan derived from the red seaweed Eucheuma spinosum was fed to guinea pigs in their drinking water over a period of 20-45 days. Occult blood in the faeces and multiple ulcers in the caecum, colon and rectum occurred in 100% of animals by the 30th day. The clinical and pathological features bear a close resemblance to human ulcerative colitis. The method provides a simple experimental model for the study of various aspects of the pathology of ulcerative lesions in the large intestine as well as the effects of therapeutic agents.

Laboratory experiments on the control of cyclops transmitting guinea worm.

Infection with the guinea worm (Dracunculus medinensis) affects millions of people living in rural areas in certain parts of the world. Usually, the standard of living is low and elaborate control measures would not be feasible. In this study, various insecticidal and molluscicidal compounds were tested in the laboratory for their toxicity to the intermediate hosts, namely, various species of cyclops, which often live in sources of potable water, such as step-wells, cisterns and ponds. Cheapness, low toxicity to mammals and ease of application, in conjunction with effectiveness against cyclops…

Electrophysiological study of the intestinal smooth muscle of the guinea-pig.

The membrane properties of single cells of intestinal smooth muscle of duodenum, jejunum, ileum, caecum and rectum of guinea-pig have been studied.1. The membrane potentials of longitudinal muscles of the duodenum, jejunum, ileum, caecum and rectum varied from 54 to 56 mV and those of circular muscles of jejunum, ileum, caecum and rectum varied from 57 to 60 mV. The ablated longitudinal muscle had a slightly lower value (50 mV) than the intact one.2. The longitudinal muscle generated spontaneous discharges but these were rare in the circular muscles of the intestine except for the caecum. Over…

Обследование антител для арбовирусов в сере детей в португальской Гвинее.

В настоящем документе описываются результаты исследования антител для нескольких арбовирусов в представительных группах детей в Португальской Гвинее. Это обследование было проведено в конце 1964 года и начале 1965 года в связи с программой вакцинации от желтой лихорадки, которая была осуществлена в период появления этой болезни в Западной Африке. Сера была изготовлена из 1103 образцов крови, собранных у 10-15-летних жителей в различных районах территории, и была протестирована на 17 различных антигенов с помощью теста на гемаглутинацию и ингибирование. Кроме того, была проведена проверка 51 се

Совпадение в аннотации оригинала
This paper describes the results of a study of antibodies to several arboviruses in representative groups of children in Portuguese Guinea. The survey was conducted in late 1964 and early 1965, in conjunction with a yellow fever vaccination programme undertaken when this disease appeared in West Africa. Sera were prepared from 1103 blood specimens collected …