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Outcomes and quality of life in conductive hearing loss.

OBJECTIVE: The goal was to measure quality of life (QOL) and hearing-specific functional status before and after treatment of conductive hearing loss (CHL). STUDY DESIGN AND SETTING: A prospective, longitudinal, outcomes-based study was performed at an academic medical center. RESULTS: Mean baseline QOL scores in CHL patients were comparable with those of the general population. Audiometric studies indicated significant improvements in hearing threshold in all treated patients. There was no significant improvement in mean global QOL scores after treatment of CHL, although there was little ro…

Measuring improved quality of life after laparoscopic Nissen fundoplication.

BACKGROUND: While the correction of pathologic gastroesophageal reflux by means of laparoscopic Nissen fundoplication (LNF) has been well documented, the psychological profiles of patients with this disease and the impact on their quality of life are less well understood. We obtained a baseline psychological profile and measured the impact of LNF on patients' quality of life with 2 standardized instruments: the psychological general well-being index (PGWB) and the gastrointestinal symptoms rating scale (GSRS). The study included 34 consecutive patients with typical symptoms of gastroesophageal…

Quality of life after laparoscopy-assisted Billroth I gastrectomy.

OBJECTIVE: To evaluate the quality of life of patients who had undergone laparoscopy-assisted Billroth I gastrectomy (LAG) for cure of cancer. SUMMARY BACKGROUND DATA: In 1994, the authors reported the first case of LAG for early gastric cancer, and this approach quickly has been adopted by Japanese surgeons. However, little is known about the subjective clinical results of this less invasive surgery. METHODS: Quality of life was estimated using the 24-item questionnaire with a scoring system of 1, 2, and 3 and was compared between 41 consecutive patients with LAG and 35 with conventional op…

Cost effectiveness and quality of life in knee arthroplasty.

Few studies quantitate the cost of a quality well being as produced by arthroplasty surgery. The objective was to use the Quality of Well Being Index to calculate the cost per quality of well year in knee arthroplasty surgery. The difference in Quality of Well Being Index scores before and after the intervention was calculated and multiplied by the patient's life expectancy. The procedure cost was divided by this quantity resulting in the cost of a quality well year. One hundred patients underwent a primary knee arthroplasty. There were 30 males (average age, 62 years old) and 70 females (aver

Quality of life in children with well-controlled epilepsy.

In our pediatric neurology clinic, we noticed that some of the children and adolescents with well-controlled epilepsy seemed to have difficu … ic and social difficulties. A simple tool like this questionnaire can be used to help nurses assess quality of life issues in children and adolescents with epilepsy.

Quality of Life in patients with resected oesophageal cancer.

Quality of Life (QL) is hard to assess and seldom measured in patients having carcinomas with an unfavourable prognosis. Oesophageal cancer is one of the malignancies with a low 5-year survival rate. Dysphagia (problems in swallowing food) is considered to be the most important indicator of QL in patients with oesophageal carcinoma. Moreover, the psycho-social aspects and subjective QL in cancer have recently gained importance. The present study investigated QL in a 132 patients with oesophageal cancer. Eighty-three of them had a surgical operation (removal of part of the oesophagus and part o…

Quality of life in patients with advanced heart failure.

Although evaluation of the treatment of congestive heart failure is usually based on objective clinical outcomes, patient self-assessment is increasingly recognized as an important component of evaluation. A study was designed to measure the quality of life of 134 patients with symptoms of advanced heart failure who were being evaluated for possible heart transplantation. The patients' quality of life was assessed using a mix of subjective and objective measures, including functional status, physical symptoms, emotional state, and psychosocial adaptation. There was no significant relationship …

Loneliness, quality of life, and life satisfaction among older adults: the mediating role of resilience.

Loneliness is a psychosocial factor associated with poorer quality of life and subjective wellbeing in later life. Few studies have examined whether resilience helps explain these associations among Korean older adults. This cross-sectional study examined whether resilience statistically mediated the associations of loneliness with quality of life and life satisfaction among Korean older adults. Data were drawn from the National Mental Health Survey of Korea 2021. Of 1,037 eligible adults aged 65-79 years, 1,018 participants with complete data were included in the analyses. Loneliness-related …

Evaluating Satisfaction and Quality of Life with Elpenhaler: A Pooled Analysis of Real-Life Studies.

PURPOSE: Patient adherence and satisfaction are critical for effective asthma and chronic obstructive pulmonary disease (COPD) management, as adherence strongly influences symptoms and prognosis. Patient-reported outcomes, including treatment satisfaction and quality of life, provide valuable insights into the effectiveness of therapeutic interventions from the perspective of individual patients. This study evaluated patient satisfaction with the Elpenhaler device and its impact on quality of life in routine clinical practice. PATIENTS AND METHODS: Individual participant data were pooled from…

Is my life going to change?-a review of quality of life after rectal resection.

Rectal resection is a common practice for colorectal surgeons. The causes of this procedure are varied. The most frequent is cancer, but also inflammatory bowel disease, endometriosis, and rectovaginal or rectourethral fistulas. The loss of the normal rectal reservoir function, urinary problems, sexual dysfunction or pelvic pain are frequently reported in patients after rectal surgery and these disorders markedly affect the overall quality of life (QoL). In the last decades, rectal surgery has radically changed, with the development of surgical techniques, and it has progressed from abdominope…

Adaptation of the Good Spirit, Good Life quality of life tool for remote Indigenous Australians.

PURPOSE: The Good Spirit, Good Life (GSGL) assessment tool was co-developed in urban and regional Australia to address quality of life (QoL) for older Aboriginal and Torres Strait Islander peoples and inform culturally responsive care. This study aimed to determine the acceptability and validity of the GSGL tool in Australian remote settings. METHODS: A co-design methodology was applied to this study. Yarning groups were conducted in 5 communities across 2 remote regions of Australia with older Aboriginal and Torres Strait Islander people. Required adaptations to the tool were refined with go…

The impact of spontaneous intracranial hypotension on social life and health-related quality of life.

OBJECTIVE: Spontaneous intracranial hypotension (SIH), which is often caused by a spinal cerebrospinal fluid leak, is an important cause of disabling headaches. Many patients report devastating changes in their quality of life because of their symptoms. This study aimed to evaluate the impact of SIH on patients' social/ working life and health-related quality of life (HRQoL). METHODS: We included consecutive patients with proven SIH treated at our institution from January 2013 to May 2020. Patients were contacted and asked to complete the 15D questionnaire for the collection of HRQoL data and…

Association of post-stroke hemiplegic shoulder pain with sleep quality, mood, and quality of life.

BACKGROUND: Hemiplegic Shoulder Pain (HSP) is a prevalent post-stroke complication, characterized by paralysis, spasticity, altered sensatio … gnificantly impacts the rehabilitation process, as evidenced by the negative effects it can have on quality of life (QoL), sleep quality, and mental status.This study aimed to determine the relationships between pain intensity, sleep quality, depressive symptoms and QoL in patients with post-stroke HSP. METHODS: This study was a cross-sectional survey of patient …

Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.

BACKGROUND: This study estimated the long-term changes of opioid agonist treatment (OAT) in quality of life (QOL) and quantified the quality-adjusted life years (QALY) from the loss of quality-adjusted life expectancy (QALE) in heroin users. METHODS: A total of 1283 heroin users stratified by OAT were linked to the National Mortality Registry for 8 years (2006-2014) to obtain survival functions, which were extrapolated to lifetime by applying a rolling extrapolation algorithm to survival ratio between the sub-cohorts and age- and sex-matched referents simulated from vital statistics of Taiwan…

To what extent is quality of life impaired in vitiligo? A multicenter study on Italian patients using the dermatology life quality index.

BACKGROUND: It is believed that vitiligo has an impact on the overall patient quality of life (QoL). OBJECTIVE: To estimate QoL in a fairly large sample of Italian vitiligo patients by using the Dermatology Life Quality Index (DLQI) questionnaire. METHODS: One hundred and sixty-one vitiligo patients referred to 9 dermatological centers were offered to participate by filling in the Italian version of the DLQI questionnaire. RESULTS: The mean total DLQI score was 4.3 (SD ±4.9; range: 0-22). In multivariate analysis, DLQI >5 was associated with female gender, stability of the disease over time…

Social functioning as a domain of quality of life in adults with obesity: results of the phase 2 validation of the Obesity Quality of Life Instrument.

OBJECTIVES: The aim of this study is to examine social functioning as a key domain of obesity-related quality of life (QoL) using the updated Obesity Quality of Life Instrument (OQI-3) v. 2. MATERIAL AND METHODS: The study was conducted in 2024 among adult patients diagnosed with obesity treated at a hospital dietary clinic in Warsaw, Poland. The study continued the validation work on the OQI-3 instrument following a pilot study. The updated OQI-3 v. 2 consists of 3 sections: 1) gender-adjusted workplace vignettes assessing perceived attitudes and emotions, 2) a multiple-choice list of obesit…

Assessing the Impact of Dermatophytosis on Quality of Life Using the Dermatology Life Quality Index: A Real-World Cross-Sectional Study From India.

BACKGROUND AND OBJECTIVE: Dermatophytosis has emerged as a chronic, recurrent, and high-burden dermatosis in India, with increasing reports of extensive involvement and treatment difficulty. Although clinical assessment is routinely performed, patient-reported quality of life (QoL) evaluation is inconsistently integrated into practice. This multicentric real-world study aimed to assess the QoL burden associated with dermatophytosis using the Dermatology Life Quality Index (DLQI). METHODS: A cross-sectional study was conducted between April and October 2025 involving clinically diagnosed derma…

Mapping Functions in Health-Related Quality of Life: Mapping from Two Cancer-Specific Health-Related Quality-of-Life Instruments to EQ-5D-3L.

BACKGROUND: Clinical trials in cancer frequently include cancer-specific measures of health but not preference-based measures such as the EQ-5D that are suitable for economic evaluation. Mapping functions have been developed to predict EQ-5D values from these measures, but there is considerable uncertainty about the most appropriate model to use, and many existing models are poor at predicting EQ-5D values. This study aims to investigate a range of potential models to develop mapping functions from 2 widely used cancer-specific measures (FACT-G and EORTC-QLQ-C30) and to identify the best model

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… Introduction In the United Kingdom, the National Institute for Health and Care Excellence (NICE) recommend the EQ-5D to measure preference-based health-related quality of life (HRQL) to estimate quality-adjusted life years (QALYs) in economic evaluations. 1 It has been demonstrated that the EQ-5D-3L … Table 1 Characteristics of the FACT-G and QLQ-C30 Data Sets For FACT-G, higher scores indicate better well-being and quality of life. The EORTC QLQ-C30 dimension score ranges from 0 to 100; higher scores indicate better functioning and quality of life. …