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Integrative Oncology for High-Grade Glioma: A Case Report on the Combined Effects of Oncothermia and Complementary Therapies.

High-grade gliomas are aggressive brain tumors with a poor prognosis despite conventional treatments such as surgery, radiation, and chemoth … zure. He refused conventional radiation therapy due to concerns about side effects and opted for an integrative medicine protocol. This protocol included oncothermia, high-dose vitamin C therapy, hydrogen inhalation, ozone therapy, magnet therapy, fasting, acupuncture, pulsed electromagnetic field therapy, yoga therapy, hydrotherapy, biologicals, and dietary modificat …

Integrative Approaches to Prostate Disease Management: Nutrition, Exercise, and Lifestyle Modifications.

Prostate-related conditions, including benign prostatic hyperplasia, prostatitis, and prostate cancer, represent significant health concerns, particularly among aging men. This study utilized a comprehensive review of existing literature and case studies to explore the effectiveness of integrative approaches, emphasizing nutrition, exercise, and lifestyle modifications, in managing prostate diseases. Data were collected from peer-reviewed journals, clinical trials, and meta-analyses focusing on dietary patterns, physical activity, and complementary therapies. The findings were synthesized to p

Pain care for patients with epidermolysis bullosa: best care practice guidelines.

BACKGROUND: Inherited epidermolysis bullosa (EB) comprises a group of rare disorders that have multi-system effects and patients present with a number of both acute and chronic pain care needs. Effects on quality of life are substantial. Pain and itching are burdensome daily problems. Experience with, and knowledge of, the best pain and itch care for these patients is minimal. Evidence-based best care practice guidelines are needed to establish a base of knowledge and practice for practitioners of many disciplines to improve the quality of life for both adult and pediatric patients with EB. M

Integrated health care for patients with motor neurone disease.

This article presents the findings from a study trip to Kaiser Permanente (KP), a private healthcare provider in the USA. The aim of the trip was to understand how healthcare integration is managed in KP and how this might help patients in the UK with motor neurone disease (MND). This article makes reference to the American and British healthcare systems, identifying the simple differences between health economies, and their impact on health care, with specific reference to MND. The trip was undertaken as part of the author's ongoing work on how patients with MND rate services delivered by the

An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia.

BACKGROUND: The molecular landscape of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) has been extensively characterized through single-modality studies. However, the interplay between molecular modalities and their collective influence on treatment response and outcomes remains poorly understood. METHODS: We integrated genomic, epigenomic, transcriptomic, and ex vivo drug response data from 1231 patients diagnosed with BCP-ALL. Using Multi-Omics Factor Analysis, we identified signatures explaining key aspects of the integrative molecular landscape, referred to as cross-mod

["Stronger Than Yourself": An Integrative Intervention Program to Improve Medication Adherence and Therapeutic Engagement in Pediatric Oncology Patients].

This article presents the "Stronger Than Yourself" program, developed within the integrative medicine service of the Oncology Department of Schneider Children's Medical Center of Israel. The program was designed to improve treatment adherence among pediatric oncology patients, with particular emphasis on oral medication intake. We describe the case of a 7.5-year-old girl diagnosed with acute lymphoblastic leukemia (ALL), who persistently refused to take her prescribed medication and struggled to cooperate with the medical team. Her condition required a tailored intervention to enable continuat…

The role of complementary and alternative methods in the treatment of pain in patients with cancer - current evidence and clinical practice: a narrative review.

IntroductionPain related to cancer, despite the numerous treatment options available, is still a challenge in contemporary pain medicine. The unsatisfactory treatment of cancer pain is one of the main reasons why patients seek complementary and alternative methods (CAM) and a more integrative/holistic approach to pain management. The popularity of CAM forces healthcare professionals to provide patients with current and evidence-based information on the effectiveness and safety of CAM. The aim of the paper is to present current evidence and limitations regarding CAM commonly used in the pain ma

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… Broadly conceived, integrative medicine includes Ayurvedic medicine and traditional Chinese medicine (TCM) [ 5 , 6 ]. So far, few randomized clinical trials have been conducted on CAM therapies in cancer patients, although the number of trials has significantly increased in the last decade. … As part of integrative medicine, some CAM techniques can be successfully incorporated into management of cancer patients to alleviate symptoms caused by cancer or cancer treatment. …

[Integrative oncology in everyday clinical practice: Continuing education and training].

Integrative oncology is gaining increasing importance in cancer care. Patients seek additional support that addresses not only physical, but also emotional and spiritual needs. At the same time, studies show positive effects of complementary therapy intervention on quality of life and symptom control. Nevertheless, healthcare professionals often remain uncertain in clinical practice regarding the safety, effectiveness, and communication of such therapies. This article provides an overview of continuing education and training opportunities in the field of integrative oncology in Switzerland, hi

Evaluating the shared risk factors between atherosclerotic cardiovascular disease and cancer: how significant is the link?

INTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) and cancer are the leading causes of death globally. While traditionally viewed as distinct, growing evidence reveals significant overlap in their risk factors and pathophysiology, suggesting a shared biological basis that warrants closer clinical and research attention. AREAS COVERED: This review explores modifiable lifestyle and pathological risk factors that contribute to both ASCVD and cancer, including tobacco use, poor diet, physical inactivity, environmental toxins, hypertension, hyperlipidemia, obesity, insulin resistance, a

[Yimusake alone or combined with trazodone hydrochloride for primary premature ejaculation].

OBJECTIVE: To study the clinical effects of the Chinese drug Yimusake, used alone or in combination with trazodone hydrochloride, on primary premature ejaculation (PE). METHODS: Sixty-eight primary PE patients were randomized to a control (n=32) and an experimental group (n=36), the former treated with Yimusake 1 tablet (50 mg) pre day, and the latter with 1 tablet of trazodone hydrochloride (50 mg) pre day in addition, both given orally after supper and for 4 weeks, followed by observation of the therapeutic effects. RESULTS: Eighteen cases (56.25%) responded in the control and 25 (69.44% )

[Comparative study on Chinese medical syndrome typing and treatment combined different surgical methods for treating clomiphene-resistant polycystic ovary syndrome].

OBJECTIVE: To observe the therapeutic efficacy of Chinese medical syndrome typing and treatment combined cold needle puncture drainage operation or unipolar electrocoagulation drilling technique under laparoscope for treating clomiphene-resistant polycystic ovary syndrome (PCOS). METHODS: Forty infertility patients with clomiphene-resistant PCOS were assigned to two groups using stratified random sampling method according to age, infertility time, and body mass index, 20 in each group. Patients in Group A were treated with Chinese medical syndrome typing and treatment combined cold needle pun

Traditional Chinese Medicine for treatment of cerebral palsy in children: a systematic review of randomized clinical trials.

OBJECTIVE: The objective of this study was to systematically evaluate the effects of Traditional Chinese Medicine (TCM) therapy including acupuncture, tu'ina, oral herbal medicine, herbal bathing, and collateral-channels conduct therapy for treating children with cerebral palsy (CP). METHODS: We included randomized controlled trials (RCTs) on TCM for children with CP. We searched the China National Knowledge Infrastructure, Database for Chinese Technical Periodicals, Chinese Biomedical Literature Database, databases of Chinese biomedical journals/Chinese Medical Current Contents, Wan Fang Dat

The expanding role of chronic pain interventions in multimodal perioperative pain management: a narrative review.

Surgery is a risk factor for chronic pain and long-term opioid use. As perioperative pain management continues to evolve, treatment modaliti … pain management when indicated. There may also be a role for acupuncture, music therapy, and other integrative medicine therapies. A transitional pain service can help coordinate outpatient care with inpatient perioperative pain management and promote a more personalized and comprehensive approach that can improve postoperative outcomes.

From Needles to Numbers: Leveraging Electronic Medical Records in Acupuncture Studies.

Acupuncture, a cornerstone of traditional Chinese medicine, is recognized for its therapeutic benefits in chronic pain management. However, … s approach could expand access to acupuncture and establish it as a key component of evidence-based integrative medicine. We urge physician-acupuncturists and researchers to lead this evolution in acupuncture research.

Psychoneurocutaneous medicine: past, present and future.

Psychoneurocutaneous medicine is an important and rapidly growing field. It is an integrative science created to address the interaction between the mind, nervous system and skin. Four major fields are involved: psychiatry, psychology, neurology and dermatology. The history of psychoneurocutaneous medicine is old and fascinating. Even though it is a young science only established in the last century, allusions to the nervous system and diseases of the skin can be traced back thousands of years in the literature. Characteristically, the last two centuries were of special importance for the deve

Development of medicines for rare diseases and inborn errors of metabolism: Toward novel public-private partnerships.

Medicine development for rare diseases, including inborn errors of metabolism (IEMs) is challenging. Many academic innovations fail to reach the patient, either by stranding in the translational stage or due to suboptimal patient access related to pricing or uncertain effectiveness. Expanding and solidifying the role of the academic in public-private partnerships (PPPs) may present an innovative solution to help overcome these complexities. This narrative review explores the literature on traditional and novel collaborative approaches to medicine development for rare diseases and analyzes exam

Narrative-based sexual medicine. A collection of patients' stories and clinical cases to better understand the management of erectile dysfunction with type 5 phosphodiesterase inhibitors in the real life.

INTRODUCTION: Narrative-based medicine (NBM) integrates patient stories with the clinician's perspective and scientific evidence to personalize care. This approach is particularly well suited to sexual medicine. Sexual dysfunctions - especially erectile dysfunction (ED) - are highly multifaceted conditions in which individual histories and couple dynamics substantially influence diagnosis and treatment. Traditional evidence-based tools may fail to capture this complexity, as sexual symptoms emerge from the interplay of several connected systems. . FINDINGS: This narrative review presents a se

Amyotrophic lateral sclerosis in Mainland China: clinical translational challenges and opportunities.

PURPOSE OF REVIEW: Amyotrophic lateral sclerosis (ALS) imposes a growing medical and socioeconomic burden in China. This review synthesizes recent advances in understanding ALS epidemiology, biomarker discovery, therapeutic innovations, and policy frameworks in China. It highlights the urgency of addressing challenges, including fragmented healthcare resources, translational medicine gaps, and regional inequities, while emphasizing China's unique contributions to global ALS research. RECENT FINDINGS: Chinese ALS cohorts exhibit distinct epidemiological profiles, including a younger mean age o