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Spontaneous splenic rupture complicating acute Q fever.

Q fever is usually a self-limited febrile illness that involves the lungs and the liver. Acute complications are rare. We present the case of a 30-yr-old patient with spontaneous splenic rupture during the course of acute Q fever infection. He was admitted to the hospital with high temperature and the radiological signs of an atypical pneumonia. Forty-eight hours after admission, he developed shock. Because of free intraabdominal liquid, a laparatomy was performed that revealed a tear in the enlarged spleen. A splenectomy was performed. The diagnosis of Q fever was established by a significant…

Mixed cryoglobulinemia associated with chronic Q-fever.

A 41-year-old woman who presented with purpura, glomerulonephritis and mixed cryoglobulinemia was found subsequently to have developed chronic Q-fever. Since Q-fever is a frequent cause of culture negative endocarditis in some endemic areas, the diagnosis of Q-fever endocarditis should be considered in patients presenting with mixed cryoglobulinemia of unknown cause.

Хроническая лихорадка Q: диагностика и наблюдение.

Сера была получена от 40 пациентов (25 мужчин и 15 женщин), имеющих клинические характеристики, совместимые с диагнозом хронической лихорадки Q. Имеются общие или частичные клинические данные. У всех из них были серологические данные о хронической лихорадке Q (титер I класса I, превышающий 800). Последним диагнозом была сосудистая инфекция в четырех случаях (при двух положительных культурах - коксиелла-жгуте ii), костная инфекция у двух пациентов (одна положительная культура), хронический гепатит у одного пациента и эндокардит - в 32. У последнего пациента была изолированная лихорадка с хронич

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Sera from 40 patients (25 men, and 15 women) with clinical features compatible with the diagnosis of chronic Q fever were received. Total or partial clinical data were available. All of them had serological evidence of chronic Q fever (IgG class anti-phase I titer greater than 800). The final diagnosis was vascular infection in four cases (with two positive …

Pericarditis associated with tick-borne Q fever.

A case of pericarditis associated with Q fever is described. Transmission was probably via an arthropod vector, which was most likely the kangaroo tick Amblyomma triguttatum. Complete recovery occurred in association with the use of non-steroidal anti-inflammatory agents only. This is a rare presentation of Q fever implicating transmission by a novel vector.

Glomerular nephropathy associated with chronic Q fever.

Of three patients with Coxiella burnetii endocarditis, two developed focal segmental proliferative glomerulonephritis (GN), and the third de … by immunohistologic techniques failed in two patients. The literature on the association of chronic Q fever with glomerulonephritis is briefly reviewed.

Transient severe hypoplastic anemia in Q fever.

A case of severe transient marrow hypoplasia as a complication of Q fever is described. This caused marked thrombocytopenia and anemia. The patient recovered fully over the period of 1 wk. The initial marrow showed severe hypoplasia. The subsequent regenerating marrow showed numerous epithelioid granulomas one of which had a characteristic fibrin ring.

Vaccine prophylaxis of abattoir-associated Q fever.

Q fever is an important cause of morbidity in Australian meatworkers; recently there have been sharp outbreaks of Q fever in abattoirs in several states. In an attempt to control Q fever by vaccination, 924 nonimmune volunteers at two South Australian abattoirs were inoculated with one dose of a purified, formalin-inactivated, Coxiella burneti, Henzerling strain, phase 1 vaccine. Some 56% of workers in one abattoir, and 64% in the other, seroconverted after vaccination. In the 18 months after vaccination, no Q fever occurred in fully vaccinated subjects, whereas there were 34 cases in 1349 unv…

Q fever epidemic in Victorian general practice.

In 1979, 110 people associated with a local rural abattoir presented with an acute febrile illness thought to be Q fever. Of these, 70 were shown by serotesting to have had Q fever, and one was shown to have had leptospirosis alone. Four individuals had mixed infections of Q fever with another zoonotic infection, two with leptospirosis, and two with brucellosis. Only 44% of suspected cases of Q fever were shown to have complement-fixing antibodies to Q fever four weeks after the infection, but 74% had anti-bodies 12 weeks after infection. This epidemic of Q fever occurred soon after the abatto…