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Электронные постеры

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Modern imaging techniques for monitoring patients with multiple myeloma.

Bone disease is a serious problem for many patients, often causing pathological bone fractures. A spinal collapse is a condition that affects the quality of life. It is the most frequent feature of multiple myeloma (MM), used in establishing the diagnosis and the need to start treatment. Because of these complications, imaging plays a vital role in the diagnosis and workup of myeloma patients. For many years, conventional radiography has been considered the gold standard for detecting bone lesions. The main reasons are the wide availability, low cost, the relatively low radiation dose and the

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Электронные постеры

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Complication Avoidance in Surgical Management of Vertebral Column Tumors.

The surgical management of spinal tumors has grown increasingly complex as treatment algorithms for both primary bone tumors of the spine and metastatic spinal disease have evolved in response to novel surgical techniques, rising complication rates, and additional data concerning adjunct therapies. In this review, we discuss actionable interventions for improved patient safety in the operative care for spinal tumors. Strategies for complication avoidance in the preoperative, intraoperative, and postoperative settings are discussed for approach-related morbidities, intraoperative hemorrhage, wo

Hypercalcemia of malignancy in metastatic esophageal squamous cell carcinoma with simultaneous PTHrP and calcitriol overproduction: A case report with literature review.

INTRODUCTION AND IMPORTANCE: hypercalcemia of malignancy is a severe complication of malignancy and associated with poor prognosis. Four mechanisms are implicated in this metabolic disorder, including excess parathyroid-related peptide secretion, focal osteolysis secondary to bone metastasis or multiple myeloma, excess calcitriol production, and ectopic parathyroid hormone production. Humoral hypercalcemia of malignancy secondary to isolated PTHrP or calcitriol overproduction is known; however, hypercalcemia of malignancy due to simultaneous PTHrP and calcitriol overproduction is less well kno

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… Case presentation A 63-year-old male presented by ambulance with 3 months of dysphagia with solid and liquid food, 7 days of right lower rib cage pleuritic chest pain, and 5 days of constipation associated with nausea, vomiting, poor oral intake, and generalized weakness. …

Е-постеры.

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… In this project, the model of the spine, developed with the musculosketetal modeling software OPENSIM, constitutes the complete thoracolumber spine and rib cage. Estimated trunk muscle loads, reactions and joint moments during several postures and loads were calculated. …

Sternum Metastases: From Case-Identifying Strategy to Multidisciplinary Management.

We aimed to overview the most recent data on sternal metastases from a multidisciplinary approach (diagnosis strategies, outcome, and histological reports). This narrative review based on a PubMed search (between January 2020 and 22 July 2023) using key words such as "sternal", "manubrium", and "metastasis" within the title and/or abstract only included original papers that specifically addressed secondary sternal spreading of cancer in adults, for a total of 48 original articles (14 studies and 34 single case reports). A prior unpublished case in point is also introduced (percutaneous incisio

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… Conventional chondrosarcoma of the rib cage and sternum: Clinicopathological and molecular analysis of 27 patients treated at a single institution Hum. Pathol. 2023 136 63 74 10.1016/j.humpath.2023.03.011 37019410 83. Agrawal M. Patil A. James T. Kumar N. Premalata C.S. …

Oral Presentations

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A Standardized Method for Vertical Sleeve Gastrectomy Bariatric Surgery Investigations in Cancer.

Obesity is a global epidemic that has affected the lives of over 14% of adults worldwide and over a third of Americans. Obesity is associated with the increased risk of thirteen obesity-associated cancers and poor cancer outcomes. Bariatric surgery is the most effective method of sustained weight loss and has been steadily increasing in clinical use over the past 4 decades. Importantly, bariatric surgery is established to decrease cancer risk. Vertical sleeve gastrectomy (VSG) is currently the most common bariatric surgery procedure. To evaluate underlying mechanisms of bariatric associated ca

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… Using sharp surgical scissors, make a midline laparotomy incision to open up the skin, leaving the abdominal wall intact, from the base of the rib cage down to the lower abdomen ( Figure 6A ). 4. With closed scissors, separate the skin from the muscle layer. 5. …

Биология и болезни крыс

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Rapid Fire

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Oral Presentations

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Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy.

Colon cancer is the second most common cause of cancer mortality in the Western world with metastasis commonly present at the time of diagnosis. Screening for propagation and metastatic behavior in a novel chimeric-mouse colon cancer model, driven by mutant p53 and β-Catenin, led to the identification of a unique, invasive adenocarcinoma. Comparison of the genome of this tumor, CB42, with genomes from non-propagating tumors by array CGH and sequencing revealed an amplicon on chromosome five containing CDK6 and CDK14, and a KRAS mutation, respectively. Single agent small molecule inhibition of

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… A small incision was made on the back to the right of the spine directly below the rib cage line. … A small incision was made on the abdominal body wall slightly to the left of the midline between the genitals and the rib cage. …

Oral Presentations

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E-Posters

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Spinal brown tumors as a rare cause of spinal cord compression: Report of case series.

INTRODUCTION AND IMPORTANCE: Brown tumors (BTs) are rare benign osteolytic lesions that arise in the context of uncontrolled hyperparathyroidism. They mostly located in the large bone and rarely in the spine. Spine involvement can cause neurologic symptoms and rarely spinal cord compression. The aim of this study is to diagnose BTs of the spine in presence of spinal cord compression symptoms leading to appropriate treatment. CASE PRESENTATION: Retrospective study of 4 cases of Brown tumors revealed by spine cord compression and rapidly operated in our neurosurgery department between 2014 and

Oral Presentations

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State-of-the-art imaging for diagnosis of metastatic bone disease.

Metastatic bone disease (MBD) is common-it is detected in up to 65-75% of patients with breast or prostate cancer, in over 35% of patients with lung cancer; and almost all patients with symptomatic multiple myeloma have focal lesions or a diffuse bone marrow infiltration. Metastatic bone disease can cause a variety of symptoms and is often associated with a poorer prognosis, with high social and health-care costs. Population-based cohort studies confirm significantly increased health-care utilization costs in patients presenting with cancer with MBD compared with those without MBD. The prolong

A Case of Autoimmune Hepatitis Initially Manifesting as Hepatic Encephalopathy.

Autoimmune hepatitis (AIH) is a T-cell-mediated liver disease characterized by elevated transaminases, circulating autoantibodies, hypergammaglobulinemia, and interface hepatitis. A 66-year-old female patient visited our department due to recurrent episodes of altered consciousness, sleep-wake inversion, and asterixis, indicating hepatic encephalopathy (HE). Her liver biopsy results clearly demonstrated interface hepatitis. The patient's severe HE does not parallel her relatively stable liver function and was attributed to a wide retroperitoneal collateral vein shunting blood directly into the

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… Her abdomen was distended without tenderness or rebound tenderness; the liver and spleen were not palpable below the rib cage. Edema was noted in her eyelids, with symmetrical pitting edema below the knees. …