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Respiratory symptoms associated with low level sulphur dioxide exposure in silicon carbide production workers.

Relations between pulmonary symptoms and exposure to respirable dust and sulphur dioxide (SO2) were evaluated for 145 silicon carbide (SiC) production workers with an average of 13.9 (range 3-41) years of experience in this industry. Eight hour time weighted average exposures to SO2 were 1.5 ppm or less with momentary peaks up to 4 ppm. Cumulative SO2 exposure averaged 1.94 (range 0.02-19.5) ppm-years. Low level respirable dust exposures also occurred (0.63 +/- 0.26 mg/m3). After adjusting for age and current smoking status in multiple logistic regression models, highly significant, positive, …

Artificial Feeding of Hard Ticks Using Silicone Membranes.

Artificial tick feeding systems (ATFS) provide an ethical alternative to using experimental animals for feeding ticks. Silicone membrane-based systems enable controlled feeding of diverse Ixodid tick species and life stages while supporting the 3R principles to replace, reduce, and refine animal use. Here, we present a protocol for silicone membrane-based ATFS, outlining practical steps, essential components, and key troubleshooting considerations.

Extraocular silicone oil deposition: a clinicopathologic case series.

PURPOSE: To characterize the clinicopathologic features of extraocular silicone oil (SO) migration in the ocular adnexae, including the conjunctiva, eyelid, and orbit (CEO). METHODS: Retrospective, single-institution case series. The Florida Lions Ocular Pathology Laboratory database at the Bascom Palmer Eye Institute was searched for surgical specimens diagnosed with “silicone oil” involving the ocular adnexae from 1997 to 2023. Clinical and histopathologic features were reviewed. All specimens were stained with hematoxylin-eosin, and immunohistochemical stains for histiocytes CD68 (M1, pro-…

Osteopontin attenuates the foreign-body response to silicone implants.

The inflammatory process resulting in the fibrotic encapsulation of implants has been well studied. However, how acellular dermal matrix (ADM) used in breast reconstruction elicits an attenuated foreign-body response (FBR) remains unclear. Here, by leveraging single-cell RNA-sequencing and proteomic data from pairs of fibrotically encapsulated specimens (bare silicone and silicone wrapped with ADM) collected from individuals undergoing breast reconstruction, we show that high levels of the extracellular-matrix protein osteopontin are associated with the use of ADM as a silicone wrapping. In mi…

3D printable and stimuli-responsive colorimetric silicone composites.

Silicone composites represent one of the most widely used soft, stretchable and biocompatible materials for a variety of applications such as medical implants, cosmetics, and soft robots. However, most of the existing silicone composites are either colorless or non-stimuli-responsive, which limits their applications as sensors. Herein, we report additive manufacturing of 3D printable and stimuli-responsive colorimetric silicone composites mixed with different functional dyes. Specifically, colorimetric silicone composites in the form of 2D films and 3D complex geometries such as baskets have b…

Computed Tomographic Appearance of Intraocular Silicone Oil in a Dog.

A 12-year-old male neutered miniature Schnauzer underwent computed tomography of the head for evaluation of a sublingual mass. The dog had prior bilateral pars plana vitrectomies with silicone oil tamponade and endolaser retinopexy for treatment of retinal detachment. On evaluation of the computed tomographic images, the vitreous chambers contained a large volume of smoothly marginated hyperattenuating material with a mass-like appearance, consistent with silicone oil. The imaging characteristics of silicone oil on computed tomography can be a source of diagnostic confusion, underscoring the i…

Silicone Migration from Intact Saline Breast Implants.

Breast augmentation is a widely performed surgical procedure worldwide, predominantly using silicone gel-filled implants. Concerns have primarily revolved around ruptures and the potential health risks associated with leaked silicone from silicone gel-filled implants. Cases of silicone migration from the shell of saline breast implants remain scarce. This case report introduces a unique case of a 66-year-old patient with silicone migration from intact saline breast implants. The patient presented with a range of symptoms consistent with breast implant illness. Radiological findings suggested t…

Multimodal imaging and histopathological evaluation in silicone oil keratopathy.

PURPOSE: To describe features in silicone oil keratopathy using multimodal imaging and histopathological examination. METHODS: Case report. RESULT: A 21-year-old male developed right corneal decompensation in the heavy SO (HSO)-filled eye. The patient underwent an initial lensectomy, pars plana vitrectomy (PPV) and HSO tamponade due open-globe injury with corneal wound, lens damage and in two retained intravitreal glass foreign bodies, followed by a revisional PPV with HSO tamponade due to tractional detachment associated with proliferative vitreoretinopathy and epiretinal membrane. One mont…

Biomimetic-Engineered Silicone Hydrogel Contact Lens Materials.

Contact lenses are one of the most successful applications of biomaterials. The chemical structure of the polymers used in contact lenses pl … gen permeability and biocompatibility, improving overall comfort, and duration of use. For example, silicone hydrogel contact lenses with high oxygen permeability were developed to extend the duration of use. In addition, controlling the surface properties of contact lenses in direct contact with the cornea tissue through surface polymer modification mimi …

The Prevalence of Hearing Impairments in Women with Silicone Breast Implants.

Many women with silicone breast implants (SBIs) report non-specific complaints, including hearing impairments. Hearing impairment appears to be associated with a number of autoimmune conditions. The current study aimed to evaluate the prevalence and severity of hearing impairments among women with SBIs and to explore potential improvements in their hearing capability following implant removal. Symptomatic women with SBIs (n = 160) underwent an initial anamnestic interview, and women who reported hearing impairments were selected for the study. These women completed self-report telephone questi…

Silicone Facial Implants, to Fixate or Not to Fixate: A Narrative Review.

Silicone implants are one of the most widely used implants for facial augmentation, especially in the chin, mandibular angle, and malar area, utilizing different surgical approaches. Despite their various advantages, many complications have also been reported, including hematoma, infection, bone resorption, numbness, displacement, and asymmetry. This study aims to evaluate the need for facial-implant fixation and compare and contrast fixated and nonfixated facial silicone implants in different facial sites. A narrative review of the topic of facial-implant stabilization using the PubMed databa…

Atropine-eluting silicone contact lenses for myopia control.

Myopia, also known as nearsightedness, is one of the prime reasons for vision impairment worldwide. Atropine in topical ophthalmic solutions … this work, an atropine-eluting contact lens was developed by encapsulating an atropine implant in a silicon-based contact lens, towards functioning in vision correction and controlling myopia. The safety and effectiveness of this atropine-eluting contact lens were verified with rabbit and guinea pig models. The results showed that the lenses reduced the s …

[Extraocular silicone oil migration to orbit: a case report].

Silicone oil insertion is a common modality in vitreoretinal surgeries after ocular perforating injury. It needs surgical removal after several months. Extraocular silicone oil migration to orbit and eyelid is uncommon complication. We reports a case of silicone oil migration to orbit and eyelid. A 41-year-old male presented with left upper eyelid swelling following silicone oil injection 3 years before admission. Orbital computed tomography scan showed multiple high-density well-defined masses in vitreous, left upper eyelid and orbit. We diagnosed the patient with orbital and eyelid mass, mea…

Trephination and silicone tube intubation in the treatment of canalicular obstruction.

PURPOSE: To evaluate the efficacy of trephination and monocanalicular/bicanalicular silicone tube use depending on the number of affected canaliculi in patients with canalicular obstruction. METHODS: This retrospective study included 46 eyes of 36 patients who underwent trephination and silicone tube intubation performed by a single experienced oculoplastic surgeon due to canalicular obstruction between 2005 and 2020. Monocanalicular silicone tube was applied to patients with one canalicular obstruction, and bicanalicular silicone tube was applied to those with the upper and lower canalicular…

Silicone Granulomas at the Peripheral Intravenous Cannula Puncture Site.

Different adverse reactions to silicone present in cosmetic fillers, implants, or medical devices have been reported. The granulomatous reaction on the injection site due to catheters' silicone coating is an infrequent complication, which may be clinically difficult to suspect. Although the definitive diagnosis requires identification of the silicone with techniques such as X-ray spectroscopy, the possibility of involvement of silicone, as well as the histopathologic demonstration of granulomas with refractile, nonpolarizable, and nonstainable material strongly suggests this diagnosis. Moreove…

Direct ink writing of tough, stretchable silicone composites.

In this work, we report 3D printable soft composites that are simultaneously stretchable and tough. The matrix of the composite consists of polydimethylsiloxane containing octuple hydrogen bonding sites, resulting in a material significantly tougher than conventional polydimethylsiloxane. Short glass fibers are also added to the material. Prior to solvent evaporation, the material possesses a viscoelastic yield stress making it suitable for printing via direct ink writing. We mechanically characterize the printed composite, including fracture tests. We observe robust crack deflection and delay

Бесплатный силиконовый грануломатоз и гиперкальцемия в трансгендерной женщине.

ВВЕДЕНИЕ: Недуг витамина D является редкой, но важной причиной гиперкальцемии. Грануломатное заболевание является одной из основных причин расстройств витамина D и часто ассоциируется с саркоидозом, туберкулезом, а в данном случае с грануломатозом иностранного тела. Жидкий или инъекционный силикон используется в качестве наполнителя косметического контура тела. Трансгендерные пациенты могут обращаться за инъекцией силикона в рамках операций по утверждению пола. Формирование грануломы является редким, но хорошо описываемым осложнением инъекционного силикона.ОПИСАНИЕ СЛУЧАЙ: А 40-year-old, получ

Совпадение в аннотации оригинала
INTRODUCTION: Vitamin D derangements are a rare but important cause of hypercalcemia. Granulomatous disease is a primary cause of vitamin D derangements and is frequently associated with sarcoidosis, tuberculosis, and in the present case, foreign body granulomatosis. Liquid or injectable silicone is used as a filler for cosmetic body contouring. Transgender …

Verapamil-containing silicone gel reduces scar hypertrophy.

A hypertrophic scar is a common dermal fibroproliferative lesion usually treated with topical silicone. Verapamil, a type of calcium channel blocker, is considered a candidate drug for the treatment of hypertrophic scars. Here, we report that the addition of verapamil to topical silicone gel enhances treatment outcomes of hypertrophic scars. Upon creation of hypertrophic scars with the rabbit ear model, varying concentrations of verapamil-added silicone gel (0.1, 1, and 10 mg/g) were applied daily for 28 days. After the animals were euthanised, microscopic measurement was performed for (a) sca…

Correction of a Leaking Stoma: Using Silicone Block Insertion.

BACKGROUND: Changes in abdominal contour, including peristomal indentations, can cause leakage of stoma effluent and other complications. P … dest improvement occurred following fasciocutaneous V-Y advancement flap surgery. After 7 months, a silicone block was inserted in the peristomal indentation. After 1 year of follow-up, the outcome remained satisfactory and no additional procedures were needed. CONCLUSION: In this case, silicone block insertion was an effective and minimally invasive alt …