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Radiation therapy in the treatment of pituitary tumors.

The treatment of pituitary tumors has progressed into a multidisciplinary approach that involves neurosurgeons, radiation oncologists, and endocrinologists. This has allowed improved outcomes in treatment of pituitary tumors due to a combination of surgical, medical, and radiation therapies. In this study, the authors review the role of radiation therapy in the treatment of pituitary adenomas.

Recent Population-Level Trends in Utilization of Outpatient Medical Oncology Services.

PURPOSE: Despite growing demand for medical oncology services, there is limited literature on trends in service utilization, and current workload models focus solely on incident caseloads. We characterized population-level trends in outpatient medical oncology service utilization among patients diagnosed with common solid tumors. METHODS: A cohort of all patients age ≥18 years, diagnosed between January 2015 and December 2022 with one of the seven solid tumors (lung, colon, rectal, pancreas, breast, melanoma, or prostate cancer) was identified from the Ontario Cancer Registry. Administrative

Decentralizing Post-Treatment Follow-Up for Cervical Cancer in Rwanda: Perspectives of Survivors and Clinicians.

PURPOSE: Cervical cancer incidence is increasing in Rwanda, leading to a growing population of survivors requiring long-term follow-up. The current oncologist-led survivorship model is not sustainable, given the limited oncology workforce and persistent geographic and financial barriers to specialist care. This study explored survivors' and clinicians' perspectives on decentralizing post-treatment cervical cancer follow-up to district hospitals. METHODS: We conducted semistructured, in-depth interviews with 33 cervical cancer survivors, six oncologists at the Rwanda Cancer Center, and four gy…

PleThora: Pleural effusion and thoracic cavity segmentations in diseased lungs for benchmarking chest CT processing pipelines.

This manuscript describes a dataset of thoracic cavity segmentations and discrete pleural effusion segmentations we have annotated on 402 computed tomography (CT) scans acquired from patients with non-small cell lung cancer. The segmentation of these anatomic regions precedes fundamental tasks in image analysis pipelines such as lung structure segmentation, lesion detection, and radiomics feature extraction. Bilateral thoracic cavity volumes and pleural effusion volumes were manually segmented on CT scans acquired from The Cancer Imaging Archive "NSCLC Radiomics" data collection. Four hundred

Development and Implementation of a Continuing Medical Education Program in Canada: Knowledge Translation for Renal Cell Carcinoma (KT4RCC).

An in-person multidisciplinary continuing medical education (CME) program was designed to address previously identified knowledge gaps regar … %), Québec City (18; 35%), and Montréal (7; 13%) and were staff urologists (21; 40%), staff medical oncologists (9; 17%), fellows (5; 10%), residents (16; 31%), and oncology nurses (1; 2%). The mean pre-CME test score was 61% and the mean post-CME test score was 70% (p = 0.003). Twenty-one participants (40%) completed the 3-month post-CME test. Of those that …

Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer.

The aim of this study was to describe the type of risk-reducing gynaecologic surgery (RRGS) and the extent of pathological evaluation being … predictors of adequate surgery were surgeon type (OR = 20; 95% CI 2-167; P = 0.005 for gynaecologic oncologists versus general gynaecologists), more recent surgery (OR = 1.33/year; 95% CI 1.07-1.67; P = 0.012) and younger patient age (OR = 0.93/year of age; 95% CI 0.87-0.99; P = 0.028). Independent predictors of adequate pathology were more recent surgery (OR …

The impact of a multidisciplinary breast cancer center on recommendations for patient management: the University of Pennsylvania experience.

BACKGROUND: Advances in the diagnosis and treatment of breast carcinoma have led to a multidisciplinary approach to management for patients with breast carcinoma. To assess the effect of this approach, the authors performed an evaluation for a cohort of patients examined in a multidisciplinary breast cancer center. METHODS: An analysis was performed for the records of 75 consecutive women with 77 breast lesions examined in consultation in a multidisciplinary breast cancer center between January and June 1998. Each patient's case was evaluated by a panel consisting of a medical oncologist, sur

Peaceful Acceptance of Illness Among Older Adults With Advanced Cancer: A Randomized Clinical Trial.

CONTEXT: Peaceful acceptance of illness is associated with lower psychological distress and increased engagement in advance care planning among adults with advanced cancer. Limited data exist on factors influencing illness acceptance in older adults. OBJECTIVES: To examine patient, caregiver, and oncologist characteristics associated with peaceful acceptance of illness in older adults with advanced cancer. METHODS: A secondary analysis of a cluster-randomized trial evaluating the impact of geriatric assessment (GA) on cancer care in community oncology practices (NCT02107443). Participants in

Accuracy of Pretreatment Ultrasonography Assessment of Intra-Abdominal Spread in Epithelial Ovarian Cancer: A Prospective Study.

The aim of this study was to test the accuracy of ultrasonography performed by gynecological oncologists for the preoperative assessment of epithelial ovarian cancer (EOC) spread in the pelvis and abdominal cavity. A prospective, observational cohort study was performed at a single tertiary cancer care unit. Patients with suspected EOC were recruited and underwent comprehensive transvaginal and abdominal ultrasonography performed by a gynecological oncologist. Sixteen intra-abdominal localizations and parameters were assessed using ultrasonography and compared with surgical-pathological status…

Thecal Sac Contouring as a Surrogate for the Cauda Equina and Intracanal Spinal Nerve Roots for Spine Stereotactic Body Radiation Therapy (SBRT): Contour Variability and Recommendations for Safe Practice.

PURPOSE: To present interobserver variability in thecal sac (TS) delineation based on contours generated by 8 radiation oncologists experienced in spine stereotactic body radiation therapy and to propose contouring recommendations to standardize practice. METHODS AND MATERIALS: In the setting of a larger contouring study that reported target volume delineation guidelines specific to sacral metastases, 8 academically based radiation oncologists with dedicated spine stereotactic body radiation therapy programs independently contoured the TS as a surrogate for the cauda equina and intracanal spi…

Modern evidence and future prospects of external body radiation therapy for lung oligometastases of breast cancer.

After Hellman and Weichselbaum defined "Oligometastasis" in 1995, several local therapies for lung oligometastases including surgical resection and external body radiation therapy were reported that improved local control (LC) and progression-free survival, overall survival, and quality of life. This suggests that oligometastases is a potentially curable state. Modern advances in radiation therapy such as stereotactic body radiation therapy (SBRT) in which high dose coverage of target lesion without exposure of normal organ is possible, and are widely used to treat solitary or a limited number

Nasofacial Anthropometric Study Among Students of Shiraz University of Medical Sciences, Iran: A Population Based Study.

Challenges in the Indian surgical oncology practice are varied - too many patients per surgeon, long operative waitlists, lacking infrastruc … dian operative time was 180 min. Pedicled TRAM flap is feasible and safe when performed by surgical oncologists, immediately after mastectomy, in the developing world. Psychosocial acceptance remains challenging, and requires dedicated counselling and inter-patient communication.

Where Oncologic and Surgical Complication Scoring Systems Collide: Time for a New Consensus for CRS/HIPEC.

INTRODUCTION: Morbidity and mortality rates after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are impo … t board using both systems. In a next step, a group of residents, experienced surgeons, and medical oncologists evaluated a set of twelve real complications, either with the Clavien-Dindo or CTCAE classification. RESULTS: The postoperative complication rate after CRS/HIPEC was 37 % (54/147), 6.8 % (10/147) were reoperated, and three (2 %) patients died. The …

Clinical assessment and pharmacologic treatment of pain in children: cancer as a model for the management of chronic or persistent pain.

This paper describes methods of assessment and pharmacologic management for chronic or persistent pain in children. This report will be a clinical one, derived from the experiences of a pediatric oncologist (P.M.Z.) and a pediatric pain consultant (L.K.Z.). Case reports will illustrate clinical assessment and management strategies.

Palliative Care for Advanced Cancer in Medicare Advantage and Physician Networks.

IMPORTANCE: Palliative care (PC) is guideline recommended to improve symptoms and quality of life concurrent with cancer-directed therapy fo … ncologist; MA beneficiaries within each plan were matched 1:1 to TM beneficiaries based on treating oncologists. Data were analyzed from November 18, 2025, to July 26, 2026. EXPOSURE: Medicare plan type. MAIN OUTCOMES AND MEASURES: Time to first PC, systemic therapy, and hospice utilization. Multivariable models estimated the associations between MA enrollm …

Association Between Smoking Status and Opioid Dose in Prescriptions Written for Breast Cancer-related Pain.

BACKGROUND: Cancer-related pain has historically been undertreated. Prescription opioids have been shown to be an integral part of the treatment of cancer pain. Despite the significant amount of scientific evidence that smoking is associated with variation in pain expression and opioid misuse in both cancer and non-cancer populations, little is known about the association between smoking status and opioid utilization in cancer populations. OBJECTIVES: To assess the association between smoking status and high-risk opioid-prescribing behaviors of oncologists prescribing opioids in the outpatien…

Professional and Psychological Impacts of the COVID-19 Pandemic on Oncology Residents: A National Survey.

PURPOSE: The COVID-19 pandemic has severely affected clinical practice in oncology, leading to organizational, ethical, and medical issues. … associated with the first peak of the COVID-19 pandemic. RESULTS: Overall, 222 residents (medical oncologists, 61%; radiation therapists, 39%) participated in our survey, representing approximately one third of all residents and fellows in France. One third of respondents had been reassigned to a COVID-19 ward. Training and research activity decreased for 8 …

DEGRO practical guideline for central nervous system radiation necrosis part 1: classification and a multistep approach for diagnosis.

PURPOSE: The Working Group for Neuro-Oncology of the German Society for Radiation Oncology in cooperation with members of the Neuro-Oncology Working Group of the German Cancer Society aimed to define a practical guideline for the diagnosis and treatment of radiation-induced necrosis (RN) of the central nervous system (CNS). METHODS: Panel members of the DEGRO working group invited experts, participated in a series of conferences, supplemented their clinical experience, performed a literature review, and formulated recommendations for medical treatment of RN including bevacizumab in clinical r

Опыт автоматической трансплантации стволовой клетки в Множественной миеломе: взгляд пациента и сторожа.

Было проведено качественное исследование опыта пациентов, получивших аутологическую трансплантацию стволовых клеток (ASCT) для лечения множественной миеломы (MM), с тем чтобы лучше понять их болезнь MM, включая первые симптомы, диагностику, ASCT и восстановление. Sixteen Участники, включая 12 пациентов с ММ и 4 В ходе совещаний целевых групп были проведены беседы с лицами, обеспечивающими уход за пациентами, имеющими MM. Боль, слабость и боль в костях были распространенными первыми симптомами среди пациентов. Диагноз MM часто делал гематолог или онколог. Пациенты после диагноза направляются к

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… For many, it took a few months (up to 6) to receive a diagnosis from their hematologist or oncologist; after diagnosis, they were referred to a specialized oncologist. … Decision-Making for ASCT Oncologists were the primary drivers in making ASCT treatment decisions. All patients said their oncologist strongly recommended ASCT. Most patients were receptive to this recommendation and readily agreed with their oncologist's recommendation. …

Evaluation and management of acute high-grade immunotherapy-related neurotoxicity.

Immune checkpoint inhibitor monoclonal antibodies allow the host's immune system to attack tumors, which has revolutionized cancer care over … . Thus, while assessing acutely ill cancer patients who are experiencing neurological symptoms, non-oncologists should be prepared to recognize, diagnose, and treat neurological immune related adverse events in addition to more familiar conditions. This narrative review is designed to update acute care clinicians on current knowledge and to present a symptom- …