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Studies on the clustering of multiple sclerosis in Finland.

The epidemiological investigation of multiple sclerosis (MS) in Finland revealed a prevalence rate of 40.3 per 100.000 inhabitants. The geographic distribution of MS was uneven in the country. MS seemed to occur more often in the western and southwestern parts of the country, where the prevalences varied between 51.7 and 62.1 This phenomenon became even more pronounced when the distribution of the disease was investigated in small geographic units. Optic neuritis showed a geographic distribution similar to that of MS, with clustering in the same parts of the country and even in the same narrow…

T and B lymphocytes in multiple sclerosis.

The percentage and total number of E and EAC rosettes, as indicators of T and B lymphocytes respectively, were studied in the blood of subjects with multiple sclerosis (MS) and normals. MS patients in acute exacerbation were found to have a decrease in E rosettes and an increase in EAC rosettes. The relationship of these findings to the pathogenesis of MS is unclear; several possible pathogenetic implications are considered.

Всемирная эпидемиология педиатрического множественного склероза: данные из Атласа Международной федерации склероза, третьего издания.

ОКРУЖАЮЩАЯ СРЕДА: Имеются ограниченные данные о глобальных темпах многократного педиатрического склероза. В этой связи мы сообщаем о предполагаемой распространенности в мире педиатрических MS. В 2020 - 2022 годах мы включили данные о распространенности заболеваний среди детей ( < < Атлас Международной федерации склероза > > ), а также данные о распространенности неюрологов среди детей (Международная ассоциация детской неврологии). Данные были разбиты на диапазоны распространенности на 100 000 человек. Страны были классифицированы по регионам ВОЗ и доходам Всемирного банка. Был пров

Совпадение в аннотации оригинала
BACKGROUND: Limited data are available on the global rates of paediatric multiple sclerosis. Here, we report on the estimated worldwide prevalence of paediatric MS. METHODS: We included paediatric prevalence data in 2020-2022 (Multiple Sclerosis International Federation Atlas of MS) and the prevalence of child neurologists (International Child Neurology Ass…

Диагностика множественных склерозов: из материалов Конференции Национального общества по проблемам множественных склерозов.

28-летняя чернокожая женщина имела как типичные, так и нетипичные особенности множественного склероза в условиях многоженства, включая психиатрическую историю, осложняющие диагностику и лечение. Этот случай иллюстрирует важность дифференциального диагноза и продольного контроля, прежде чем брать на себя обязательство по профилактике заболеваний. Особое внимание уделяется принятию решений в отношении индивидуального лечения.

Совпадение в аннотации оригинала
A 28-year-old Black woman presented with both typical and atypical features of multiple sclerosis in the setting of multimorbidity including psychiatric history, complicating diagnosis and treatment. This case illustrates the importance of differential diagnosis and longitudinal follow-up before committing to disease-modifying therapy. Individualized treatme…

Online psychological interventions to improve symptoms in multiple sclerosis: A systematic review: Online psychological interventions in Multiple Sclerosis.

The aim of this systematic review was to assess the effectiveness of Internet-based psychological interventions in the treatment of physical, socio-affective and cognitive symptoms and quality of life (QoL) in people with multiple sclerosis (pwMS) to provide currently available evidence. Systematic searches for eligible studies were carried out in four databases (August 2021) using key words. Studies were screened, data extracted, quality appraised and analysed by three independent reviewers, using predefined criteria and following the PRISMA rules. Study quality was assessed using Standard Qu…

Clinical Characteristics and Disability Progression of Early- and Late-Onset Multiple Sclerosis Compared to Adult-Onset Multiple Sclerosis.

BACKGROUND: Compared to the adult onset of multiple sclerosis (AOMS), both early-onset (EOMS) and late-onset (LOMS) are much less frequent, but are often under- or misdiagnosed. The aims of the present study were: 1. To compare demographic and clinical features of individuals with EOMS, AOMS and LOMS, and 2. To identify predictors for disability progression from relapsing remitting MS (RRMS) to secondary progressive MS (SPMS). METHOD: Data were taken from the Isfahan Hakim MS database. Cases were classified as EOMS (MS onset 18 years), LOMS (MS onset >50 years) and AOMS (MS >18 and 50 years).…

Multiple sclerosis and HIV: a case of multiple sclerosis-immune reconstitution inflammatory syndrome associated with antiretroviral therapy initiation.

Studies have suggested that the incidence of multiple sclerosis (MS) in HIV-infected (HIV+) patients is lower than that of the general population. Here, we present a case of MS in an HIV+ patient with a relatively suppressed CD4 cell count who developed clinical and radiographic disease worsening in the setting of antiretroviral therapy (ART) initiation. A 47-year-old HIV+ woman (CD4 cell count 216 cells/µl) presented with decreased vision in her right eye. Magnetic resonance imaging (MRI) revealed optic nerve enhancement and open ring-enhancing lesions in the brain concerning for demyelinatin…