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Minimizing the risk of Q fever in the hospital setting.

Q fever is caused by a rickettsial microorganism (Coxiella burnetii) harboured in sheep. The highest concentration of organisms are found in birth products. It is a very contagious organism which humans can contract by inhaling aerosolized organisms. Most commonly it leads to an acute 'flu-like illness. Rarely, chronic disease with endocarditis is fatal. Infected patients should be treated with tetracyclines or chloramphenicol. A number of outbreaks have been reported in hospital and research settings. Because of the fear of patients and staff contracting Q fever, Hospital Research Review Boar…

Acute meningoencephalitis as the sole manifestation of Q fever.

The case of a 25-year old man who presented with meningoencephalitis as the sole clinical manifestation of Q fever is described. Serological studies revealed the presence of IgM and IgG antibodies to Coxiella burnetii. The patient responded favourably to a ten-day course of i.v. ceftriaxone and was discharged without any neurological sequelae.

Lymphocytic meningitis as the sole manifestation of Q fever.

A young man who presented with a 3 week history of fever and severe headache accompanied by mild leukocytosis, was found to have lymphocytic meningitis due to Coxiella burnetti. Thus, Q fever can present as lymphocytic (aseptic) meningitis responsive to tetracycline with no evidence of pulmonary involvement.

[Q fever. A familial outbreak of 5 cases].

Five cases of acute Q fever diagnosed in the same family are reported. The epidemiological and clinical features, the therapy and evolution of the infections by Coxiella burnetti are discussed. Q fever is a condition to be considered in febrile illnesses or atypical pneumonia, particularly when developing in outbreaks. It is concluded that Q fever should be considered as endemic in some areas of this country (Basque Country, Catalonia...). Finally, we think that antibiotic therapy (tetracyclines) should be given, as it can shorten the duration of the disease and prevent the development of seve…

[Radiodiagnostic features of the pulmonary form of Q fever].

Patients with the pulmonary form of Q fever and the more rarely described pleural reaction were presented. The purpose of this work was as follows: to pay attention to all characteristics of the radiological picture of the pulmonary form of Q fever, to emphasize the importance of the radiological finding for the establishment of diagnosis, to point to the present possibilities of radiology and to put forward diagnostic procedures. Namely, when managing the patients in clinical practice, radiological examination is performed almost in the first place, the referring diagnosis is most frequently …

[Q fever in a 5-year-old girl].

The first case of Q fever in Poland in a 5-year girl is presented. A girl is inhabitant of the Lublin region where this disease is of endemic character. Q fever was diagnosed on the base of the clinical examinations and serological tests. The course of the disease was acute. Doxycycline and lincomycin were given. A short time lapse between the treatment and eradication of Coxiella burnetii antigen indicates rather spontaneous recovery.

Клинические аспекты и профилактика Q лихорадки у животных.

В последние годы в Федеративной Республике Германии было хорошо задокументировано увеличение распространенности инфекций коксиеллы в скотоводстве, а его связь с проблемами бесплодия у этих видов была показана рядом авторов. Расследования по этой проблеме сдерживаются тем, что еще один внутриклеточный агент, Chlamidia psittaci, который также может вызывать бесплодие, также широко распространен среди скота. Испытания на вакцинацию с использованием коммерческой вакцины от разбавления яйцеклеток против обоих агентов показали, что благодаря применению такой вакцины фертильность среди инфицированных

Совпадение в аннотации оригинала
In recent years, in the Federal Republic of Germany an increase in the prevalence of Coxiella burnetii infections in cattle has been well do … provement. Limited experiments with more purified experimental C. burnetii vaccines have shown that Q fever in cattle may be prevented by vaccination of young uninfected animals only. In this way herds free of C. burnetii may be established.

Seroepidemiology of Q fever in New Brunswick and Manitoba.

A seroepidemiological survey, using an indirect immunofluorescence test, was carried out on serum samples obtained from New Brunswick and Manitoba blood donors during 1986. The antigens were Coxiella burnetii phase I and phase II from strain Nine Mile. Eighty of the 503 (15.9%) Manitoba blood donors had a phase II antibody titer of greater than or equal to 1:8, while 41 (4.2%) of the 966 New Brunswick blood donors had such antibodies. We have recently diagnosed three cases of Q fever in New Brunswick but none have been diagnosed in Manitoba. Our data suggest that Q fever may be increasing in N…

A note concerning the analysis of an epidemic of Q fever.

Techniques of statistical analysis developed for the analysis of experiments, for which the usual precautions of randomization ensure independence, are not necessarily appropriate to the analysis of epidemics. An outbreak of Q Fever in a Swiss Alpine valley previously reported in the International Journal of Epidemiology is analysed to make this point.

An unexpected Q fever endocarditis. Report of a case.

A man with blood culture negative endocarditis since 1983 received in October 1984 a mitral valve bioprosthesis. Reintervention in April 1985 was performed because of a paravalvular leak. In September 1985, mitral insufficiency reappeared and high-titer phase II Q fever antibody was detected, which has since then persisted with concomitant high-titers of phase I antibody. In serum from 1983, phase II antibody was detected on reexamination in September 1985. For unexplained reasons this antibody had not been detected in 1983. The patient has since September 1985 been successfully treated with d…

Q fever in infancy: a review of 18 cases.

Infection with Coxiella burnetti (Q fever) was diagnosed in 18 children younger than 3 years of age in The Netherlands during a 16-month period. The diagnosis was confirmed serologically by means of a complement-fixation test and immunofluorescence for IgM determination. A summary of the clinical, hematologic, serologic and epidemiologic features is given. Four children had relapsing episodes of fever during several months. The problem of childhood infection with C. burnetii, particularly in relation to the possibility of intrauterine infection or infection during birth and in the neonatal per…

Q fever in the Basque Country: 1981-1984.

One hundred thirty cases of Q fever were seen in the Basque region of Spain between 1981 and 1984. Approximately 40% of these were related to epidemic outbreaks, and the remainder were isolated cases. The large majority of cases occurred in young men and women between 20 and 40 years of age. A seasonal peak coincided with lambing time in the region. Treatment had favorable outcome in each case, and no chronic disease was seen.