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Study protocol for a randomized controlled trial comparing penetrating needling and cognitive behavioral therapy for subjective tinnitus.

OBJECTIVE: To describe the protocol for a randomized controlled trial designed to evaluate the clinical efficacy of penetrating needling compared with cognitive behavioral therapy (CBT) in patients with subjective tinnitus. METHODS: This protocol describes a proposed assessor- and analyst-blinded, parallel-group randomized controlled trial. A total of 72 participants will be randomized 1:1 to a treatment group receiving penetrating needling plus health education or a control group receiving CBT plus health education. Penetrating needling will be administered five times weekly for two consecut…

The effects of cognitive behavioral therapy for insomnia on cardiovascular and immunological outcomes: A randomized-controlled study.

Insomnia disorder is associated with pathophysiological alterations that may contribute to long-term mental and physical health risks. Cognitive behavioral therapy for insomnia (CBTi) is the first-line treatment for insomnia disorder, yet its effects on physiological outcomes remain unclear. This secondary analysis of a randomized-controlled trial examined the effects of CBTi on cardiovascular and immunological biomarkers. Sixty-two participants with insomnia disorder were randomized to CBTi (N = 33, 75.8% female, Mage = 48.8 ± 17.1 years) or Waitlist (WL) control (N = 29, 75.9% female, Mage =…

Associations between anger reductions and functional improvements among veterans in brief cognitive-behavioral conjoint therapy for PTSD.

Anger is a significant problem for military veterans with posttraumatic stress disorder (PTSD). Interventions designed to treat PTSD have been shown to decrease anger, which may be associated with improvements in psychosocial functioning. Couple-based PTSD treatments, which target both PTSD and relationship functioning, may be particularly useful for improving anger and associated psychosocial functioning. Thus, the current study sought to examine whether decreases in veterans' and partners' anger following participation in a brief couple-based treatment for PTSD (brief Cognitive Behavioral Co

Gender Differences in Cognitive Behavioral Therapy Outcomes for Adolescents With ADHD: Examining the Impact of Internalizing Symptoms.

OBJECTIVE: This study investigates the effectiveness of Cognitive Behavioral Therapy (CBT) for adolescents with ADHD, while focusing on gender differences and comorbid internalizing symptoms. METHOD: A quantitative secondary data analysis was performed on 200 adolescents aged 12 to 18 years who participated in randomized control trials in either the Netherlands or Norway. RESULTS: Overall, CBT significantly reduced ADHD symptoms from pretest to posttest on parent measures; however, treatment response varied based on gender, internalizing symptoms, and treatment formats. Girls with elevated d…

Cognitive behavioral group therapy for bipolar disorder with comorbid anxiety disorder: a mixed-methods feasibility pilot study.

BACKGROUND: Half of all individuals with bipolar disorder (BD) are estimated to have or develop a comorbid anxiety disorder (AD). Comorbid AD is associated with decreased treatment response and a more severe illness trajectory. However, as only a few studies have targeted comorbid anxiety as a treatment goal in BD, this mixed-methods study aimed to assess the feasibility and preliminary effect of a cognitive behavioral therapy (CBT) based group course for comorbid ADs in people with BD. METHODS: Nine individuals with BD and comorbid AD completed a CBT group course for anxiety consisting of 15…

An international randomized waitlist-controlled trial of internet-delivered cognitive behavioral therapy for sexual urges toward children.

OBJECTIVE: Test whether Prevent It 2.0, a 9-week, anonymous internet-delivered cognitive behavioral therapy (iCBT) program, reduces the severity of sexual urges and behaviors toward children to prevent acts of child sexual exploitation and abuse. METHOD: In a randomized 1:1 waitlist-controlled trial with crossover at Karolinska Institutet, Sweden, N = 203 adults (≥18 years; 92.1% men, 0.5% women, 7.4% other; age 18-70, 66.6% aged 21-40; 49.8% Europe, 38.9% North America) were allocated to iCBT (n = 100) or waitlist (n = 103). The preregistered primary outcome was severity of sexual urges towa…

Health Care Leaders' Views About Remotely Delivered Cognitive Behavioral Therapy-Based Services for High-Impact Chronic Pain.

BACKGROUND: Chronic musculoskeletal pain remains a vexing clinical challenge, and health care systems have struggled to identify effective, scalable, and safe treatment alternatives to opioids and other higher-risk interventions. Remotely delivered cognitive behavioral therapy for chronic pain (CBT-CP) offers an evidence-based approach to meet this need. METHODS: The qualitative portion of the study aimed to advance understanding of how clinicians and health care system administrators perceive remotely delivered CBT-CP and to inform its dissemination and practical integration into health care…

Dietetic-Led Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder: Feasibility, Acceptability, and Proof-of-Concept.

OBJECTIVE: Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder (CBT-AR) is an emerging treatment for ARFID, but to date, it has only been delivered by mental health clinicians. Given the relevance of nutrition to treatment goals, we adapted the treatment to be dietetic-led (D-CBT-AR). METHOD: We conducted a pilot trial of D-CBT-AR. Participants self-referred to a multidisciplinary eating-disorder clinic in Brisbane, Australia, and attended in person or virtually. Participants rated D-CBT-AR on acceptability and feasibility. We also measured changes in ARFID psychopathol

The Development and Evaluation of a Web-Based Training Program for Cognitive Behavioral Therapy for Nightmares: CBTNightmares.org.

OBJECTIVE: Chronic nightmares are associated with a range of mental and physical health problems, including posttraumatic stress disorder, depression, alcohol use, and suicide risk. Cognitive behavioral therapy for nightmares (CBT-N) is a recommended treatment, but is underutilized because of the lack of providers trained in CBT-N. We developed and evaluated a web-based provider training for CBT-N: CBTNightmares.org. MATERIALS AND METHODS: Experts developed the content and a prototype of CBTNightmares.org. Testing occurred in 3 phases. First, licensed behavioral health providers and trainees …

Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial.

BACKGROUND: Cognitive behavioral therapy (CBT) is the most effective treatment for binge eating disorder (BED) but is limited by modest efficacy and low reach of in-person delivery. Combining mindfulness training with CBT could enhance efficacy by targeting emotion dysregulation, a key factor in BED that CBT does not adequately target. Digital delivery can enhance the reach of treatment. Accordingly, we developed CBT-based Mindful Courage, a 16-session digital intervention combining CBT and mindfulness training for BED. OBJECTIVE: The aim of this study is to conduct a pilot randomized control…

Videoconferencing Cognitive Behavioral Therapy for Panic Disorder in an Emergency Room in Mexico: A Multiple Baseline Design.

The aim of this study was to evaluate the effectiveness of a brief cognitive behavioral therapy intervention conducted via videoconference for adults with panic disorder and agoraphobia in the emergency room (ER) of a Mexican hospital. We examined the impact of the intervention on quality of life, emergency room utilization, and participants' satisfaction with the intervention and the use of telepsychology. A multiple-baseline single-case experimental design was employed. Sixteen adults diagnosed with panic disorder were assigned to one of four cohorts and received seven individual therapy ses…

Реальное наблюдение в мире усталости в множестве склерозов, сравнивая эгоистическую когнитивную поведенческую терапию с психообразованием.

Усталость является распространенным симптомом у людей с множественным склерозом (pwMS), имеющим серьезные последствия. Самоуправляемое, основанное на Интернете вмешательство в целях сокращения усталости в MS, основанное на когнитивной поведенческой терапии (CBT), было одобрено в качестве цифрового прикладного программного обеспечения в области здравоохранения (DIGA) в системе здравоохранения Германии. Однако реальных данных об эффективности не хватает. МЕТОДЫ: 165 - пациентов, прошедших проверку на усталость с использованием шкалы утомления моторных и когнитивных функций (FSMC), 129 у них диаг

Совпадение в аннотации оригинала
BACKGROUND: Fatigue is a common symptom in people with multiple sclerosis (pwMS) with severe implications. A self-guided, internet-based intervention to reduce fatigue in MS, based on cognitive behavioral therapy (CBT), is approved as a digital health application (DiGA) in the German healthcare system. However, real-world evidence for efficacy is lacking. M…

Internet-delivered cognitive behavioral therapy for adolescents with excessive worry: a randomized controlled trial with mediation analysis.

Excessive worry is common during adolescence and across psychiatric disorders. This study investigates whether: (1) internet-delivered cognitive behavioral therapy (ICBT) focused on exposure to uncertainty is effective in reducing excessive worry; (2) improvements in worry are associated with reductions in other psychiatric symptoms; and (3) changes in intolerance of uncertainty (IU) mediate worry outcomes. Adolescents (N = 62; aged 13-17 years) with excessive worry (≥30 total score on Penn State Worry Questionnaire for Children) were randomly allocated to 8 weeks of ICBT (n = 31) or a waitlis…

The role of idioms in reducing depression in university students: a study on group cognitive behavioral therapy.

PURPOSE: To evaluate the effectiveness of Culturally Adapted Cognitive-Behavioral Therapy (CA-CBT) compared to standard CBT in alleviating d … problems. However, CA-CBT did not better improve participants' emotion regulation, understanding of cognitive behavioral therapy, or reduction of cognitive distortions.At the same time, the CA-CBT group did not perform better than the standard CBT group in terms of dropout rate, treatment satisfaction, recommendation, and re-use rate. TRIAL REGISTRATION: The trial was regist …

Cognitive behavioral therapy for adult insomnia disorder in routine clinical care: a systematic review and meta-analysis.

A systematic review and meta-analysis was conducted of different types of CBTs for ID in adults treated in routine clinical care. Ovid MEDLINE, Embase OVID, and PsycINFO were systematically searched for studies published until January 2025. The effectiveness of CBT, methodological quality, and moderators of treatment outcomes were examined and benchmarked by meta-analytically comparing them with efficacy studies for ID. Thirty-two studies were included, comprising 5231 participants. Very large within-group effect sizes (ES; Hedges' g) were obtained for ID-severity at post-treatment (1.87), and

Pavlovian fear reversal learning predicts outcome of exposure-based cognitive behavioral therapy for adult obsessive-compulsive disorder.

Extinction of conditioned fear responses is assumed to relate to beneficial effects of exposure-based treatment, but few studies investigate … avlovian reversal learning experiment predicted the outcome of individual, manualized and ERP-based cognitive behavioral therapy (CBT) for 32 patients with OCD. In the first part of the experiment (acquisition stage) a picture of a face (CS+) was paired with an electrical stimulation (US) in one third of the trials while a second face (CS-) was never presented with the US. Du …

Active Components in Internet-Based Cognitive-Behavioral Therapy for Social Anxiety Disorder: A Randomized Full Factorial Trial.

INTRODUCTION: Many studies have demonstrated that social anxiety disorder (SAD) can be effectively treated with psychotherapy, particularly cognitive-behavioral therapy (CBT), including internet-based CBT (ICBT). Despite evidence-based treatments, many individuals do not sufficiently benefit from them. Identifying the active components could help improve the effectiveness of SAD treatment. This study tested the effects of four treatment components (psychoeducation, cognitive restructuring, attention training, and exposure) within ICBT for SAD to investigate its active components. METHODS: Thi

Continuous Improvement of Chronic Tinnitus Through a 9-Month Smartphone-Based Cognitive Behavioral Therapy: Randomized Controlled Trial.

BACKGROUND: Tinnitus is the perception of sound without an external auditive stimulus and can be a severe burden for affected patients. Medical guidelines recommend cognitive behavioral therapy (CBT) for tinnitus treatment, which effectively improves tinnitus-related distress and anxiety. OBJECTIVE: This study investigates the outcome of a 9-month smartphone-based CBT for patients with tinnitus. METHODS: The randomized controlled clinical trial in this study investigates the efficacy of a smartphone-based CBT for 187 patients with chronic tinnitus over a 9-month treatment period. In the init…

Internet-based cognitive behavioral therapy for alcohol use disorder: A systematic review of evidence and future potential.

INTRODUCTION: While cognitive behavioral therapy (CBT) remains a highly effective psychotherapy approach for managing Alcohol Use Disorder (AUD), its potential is hindered by workforce shortages and access barriers. In response to these challenges, Internet-Based Cognitive Behavioral Therapy (iCBT) has emerged as an innovative solution that integrates the core CBT structure with technology. In iCBT, educational materials, therapist communication and progress dashboards can be centralized in a digital format, and delivered in a self-guided, therapist-guided or blended approach. METHODS: In thi…

Efficacy of cognitive behavioral therapy-based smartphone app for smoking cessation in China: A randomized controlled trial.

BACKGROUND AND AIMS: Smoking is the leading preventable cause of premature death in China, yet less than 10% of smokers seeking to quit receive treatment. This study aimed to test the efficacy of a cognitive behavioral therapy (CBT)-based smoking cessation intervention ('Smokefree Life') via a smartphone app in China. DESIGN: A digital, parallel, single-blind, two-arm (1:1) randomized controlled trial. SETTING: This trial was conducted via 'Smokefree Life' app in the whole of mainland of China between 13 December 2021 and 15 April 2023. PARTICIPANTS: Chinese-speaking adult smokers (925 male…