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[Acaricidal activity of "Medifox" against the human itch mites Sarcoptes scabiei].

The acaricidal activity of Medifox was evaluated in terms of the itch mites to lend support to the validity of its regimen to treat human scabies. Experiments using mainly females, eggs, and larvae withdrawn from the burrows on the skin of patients with scabies were performed. Permethrin contained in 0.4% aqueous Medifox emulsion was found to affect an itch mite by contact and intestinal routes, without a marked knock-down effect; however, the signs of intoxication are irreversible and lead to the death of Medifox-treated mites. In an in vitro experiment, 100% death of specimens occurred 24-48…

[Pyrethroid exposure following indoor treatments with a dog flea powder].

UNLABELLED: Pyrethroid exposure following indoor treatments with a dog flea powder. HISTORY: A 42 year old woman reported hair loss, gastrointestinal and non-specific symptoms. The patient has lived in a council flat and kept a dog who had been regularly treated with pyrethroid containing flea powder. INVESTIGATIONS: The biological monitoring of pyrethroid meta-bolites in urine was performed using gas chromatography-mass spectrometry. The values at admission and follow-up after 4 weeks were highly elevated. Inspection of the flat revealed a humid and cramped dwelling. TREATMENT: We recommen

Mitochondria-targeted therapy with metformin and MitoQ reduces oxidative stress, improves mitochondrial function, and restores metabolic homeostasis in a murine model of Gulf War Illness.

Gulf War Illness (GWI) is a cluster of medically unexplained chronic symptoms, including neurological and gastrointestinal impairments, and muscle fatigue, suffered by veterans of the Persian Gulf War. A GWI model in C57BL/6 mice exposed to the nerve gas prophylactic pyridostigmine-bromide (PB) and the insecticide permethrin (PER) was used to test the effect of mitochondria-potentiating agents, metformin and MitoQ on chronic fatigue, observed in GWI. The exposure of mice to PB/PER resulted in enhanced oxidative stress, impaired mitochondrial function, and reduced autophagy. Treatment with the …

Management of a family outbreak of scabies with high risk of spread to other community and hospital facilities.

BACKGROUND: In developed countries, scabies is observed sporadically or as institutional outbreaks in hospitals and other health facilities. … essed to all contacts and the training of health care personnel. In addition, specific prophylaxis (permethrin 5%) was performed in 108 high-risk contacts and LTCF patients and staff. CONCLUSIONS: The control measures were successful in preventing the spread of the outbreak. However, misdiagnosis and the tendency of people to hide the symptoms caused the la …

Prevalence of antibodies to Rickettsia conorii in human beings and dogs from Catalonia: a 20-year perspective.

The incidence of Mediterranean spotted fever (MSF) in Catalonia (Spain) has decreased in the last two decades. The prevalence of antibodies … orii. A high proportion of the studied dogs (91·0%) were receiving anti-tick treatment, mainly with permethrin-imidacloprid spot-on (Advantix, Bayer, Germany). The current canine seroprevalence was not significantly different from that recorded in the 1987 survey (36.9%). In conclusion, this study shows a significant decrease in the prevalence of antibodies …

[Ectoparasites. Part 1: lice and fleas].

Ectoparasites and epidermal parasitic skin diseases are a heterogeneous group of infections of the external layer of the skin. The most comm … epeated cleansing and combing out of lice-infected hair and also local antiparasitic treatment with permethrin, pyrethrum extract, allethrin and dimeticon. Lindan which has been used for decades can no longer be used in medications after 2008 after a decision of the EU Commission. Failure of treatment of head lice can be a result of errors in the treatment w …

Oral ivermectin in scabies patients: a comparison with 1% topical lindane lotion.

Scabies. which constitutes a significant proportion of the outpatient attendance in tropical dermatology clinics, has so far been treated with lindane, crotamiton, sulphur, permethrin, etc. Ivermectin, an orally administered drug, was tried in scabies patients and compared with 1% topical lindane lotion to evaluate its effects and toxicity profile. Two hundred scabies patients were randomly allocated to one of two groups. One group received oral invermectin in a single dose of 200 micrograms/kg body weight. The other received 1% lindane lotion for topical application overnight. Patients were a…

Crusted (Norwegian) scabies in a patient with dystrophic epidermolysis bullosa.

A 13-year-old girl with severe non-mutilating recessive dystrophic epidermolysis bullosa (EB) was admitted to hospital because of a Staphylo … s successfully treated with two doses of ivermectin orally and one application of lindane ointment. Permethrin cream was not tolerated. In this patient crusted scabies may have developed because of: (i) a modified host response due to malnourishment; (ii) inability to scratch because of the absence of fingernails; and (iii) abnormal scratching behaviour beca …

Organic micropollutants in surface water across China: Occurrence and ecological risk.

Organic pollutants in surface water present considerable risks to aquatic ecosystems and human health. However, current screening efforts in … ities and variations across the six major river basins. Toxicological priority index indicated that permethrin demonstrated the highest toxicity, and dibutyl phthalate exerted the greatest risk index. Notably, fifteen compounds had risk quotients exceeding 1, signifying substantial ecological risk, with captafol, a previously unreported OCPs, exhibiting high …

Evaluation of insecticide resistance among Malaysian Aedes albopictus Skuse larvae based on revised diagnostic doses of larvicides.

The susceptibility levels of Malaysian Aedes albopictus larvae sampled from several agricultural, fogging-free residential and dengue prone … high resistance against dichlorodiphenyltrichloroethane (DDT), fenitrothion, fenthion, propoxur and permethrin (79.67% - 97.33% mortality). Moderate to high resistance were also demonstrated among all populations of Ae. albopictus larvae against temephos and chlorpyrifos (63.00% - 97.67% mortality). Except for Ae. albopictus larvae from oil palm plantations, …

Infectious Disease: Bedbugs, Lice, and Mites.

Bedbugs, mites, and scabies are ectoparasites that commonly affect humans. Bedbugs (Cimex species) were once rare in the United States but a … s tight. The diagnosis can be confirmed with dermatoscopy or microscopy. Management involves use of permethrin cream, oral ivermectin, or benzyl benzoate.

Общие условия развития кожи у детей: инфекция кожи.

Инфекции кожи являются одной из важных подкатегорий дерматологовых условий детства. К числу широко распространенных вирусных инфекций среди детей относятся бородавки, моллюски-контазиосум, болезнь ручных ног и яичников и герпес simpex. Хотя вирусные инфекции являются самоограничивающимися и часто лишь слегка симптомами, они могут вызывать тревогу, смущение и использование медицинских услуг. Для того чтобы отличать их от других кожных условий аналогичной морфологии, необходимо признать их общие и нетипичные представления. Импетиго, целлюлит и абсцесс составляют большинство детских бактериальных

Совпадение в аннотации оригинала
Skin infections account for a significant subset of dermatologic conditions of childhood. Common cutaneous viral infections in children incl … les. Scabies is the most common parasitic skin infection among children and is managed with topical permethrin. Although serious illness is not common among children returning from international travel, patients presenting with fever and rash, especially petechial or hemorrhagic lesions, require thorough evaluation. Of the numerous reportable conditions that …

Assessment of the prophylactic speed of kill of Frontline Tri-Act(®) against ticks (Ixodes ricinus and Rhipicephalus sanguineus) on dogs.

The objective of the study was to assess the speed of kill of a single topical treatment with a combination of fipronil and permethrin (Frontline Tri-Act(®)/Frontect(®)) against experimental infestations of Ixodes ricinus and Rhipicephalus sanguineus ticks on dogs. In this parallel group designed, randomised, single centre, controlled efficacy study, 16 healthy adult dogs were allocated to two groups: 8 dogs were treated with the topical combination on Day 0 and the other 8 dogs served as untreated controls. Each dog was exposed in a crate to 100 I. ricinus (50 females, 50 males) and 50 R. san…

Crusted demodicosis in an immunocompetent pediatric patient.

Demodicosis refers to the infestation by Demodex spp., a saprophytic mite of the pilosebaceous unit. Demodex proliferation can result in a n … aping revealed several D. folliculorum mites. Oral ivermectin (200 μg/kg, single dose) plus topical permethrin 5% lotion applied for 3 consecutive nights were administered. Oral ivermectin was repeated every week and oral erythromycin plus topical metronidazole cream was added. The facial lesions greatly improved within the following 3 months. While infestat …

Review: Targeting trachoma: Strategies to reduce the leading infectious cause of blindness.

The World Health Organisation (WHO) estimated that in 2002, 1.3 million people were blind due to trachoma, an eye infection caused by Chlamy … ma, but the evidence is less clear than for surgery and antibiotics. Pit latrines and spraying with permethrin insecticide may reduce the spread of trachoma via eye-seeking flies.

Epidemiology of Pediculosis capitis in elementary schools of Buenos Aires, Argentina.

The infestation with the human obligate ectoparasite Pediculus humanus capitis De Geer is a common public health problem affecting mainly schoolchildren worldwide. The aim of the present study was to investigate the infestation levels of head lice in elementary schools from Buenos Aires with resistant levels to permethrin >100. A total of 1,856 children aged 3-13 years old from eight selected elementary schools were examined for head lice. Pediculosis was observed in all the studied schools. The overall infestation rate was 29.7%. Girls were statistically significant more infested than boys, w…

Bioengineering of a cellulosic fabric for insecticide delivery via grafted cyclodextrin.

beta-Cyclodextrin (beta-CD) can be easily grafted onto cellulosic textiles through covalent bonds. In such a way beta-CD empty cavities prov … rmances. In this work we report the inclusion of two different products, the pyrethroid insecticide permethrin (PERM) and the insect repellent N,N-diethyl-m-toluamide (DEET), into beta-CD molecules grafted on cotton fabric. UV-vis spectrophotometry and thermal analysis confirmed the presence of the guest molecules on the fabric surface. Bioassays were carrie …

Clinical and parasitological aspects on human scabies in Qualyobia Governorate, Egypt.

In the last decade, human scabies caused by Sarcoptes scabiei and other non human strains is one of the most common contagious parasitic dis … exposure to infestation. The patients were successfully treated with 5% sulfur precipitate and 2-5% permethrin. The whole results were discussed on the light of the previous work.