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Vegans, Vegetarians and Pescatarians Are at Risk of Iodine Deficiency in Norway.

Low iodine intakes have been documented in different population groups in Norway. We aimed to assess iodine status, dietary intake, supplement and macroalgae use, and iodine knowledge in vegans, vegetarians and pescatarians. In this study, 115 vegans, 55 vegetarians and 35 pescatarians from the Oslo region of Norway, aged 18-60 years, participated. A spot urine sample was collected along with a dietary assessment of iodine intake, supplement and macroalgae use. The median urinary iodine concentration (MUIC) in vegans was 43 µg/L (moderate iodine deficiency), in vegetarians 67 µg/L and in pesca

Bromoanisoles and methoxylated bromodiphenyl ethers in macroalgae from Nordic coastal regions.

Marine macroalgae are used worldwide for human consumption, animal feed, cosmetics and agriculture. In addition to beneficial nutrients, macroalgae contain halogenated natural products (HNPs), some of which have toxic properties similar to those of well-known anthropogenic contaminants. Sixteen species of red, green and brown macroalgae were collected in 2017-2018 from coastal waters of the northern Baltic Sea, Sweden Atlantic and Norway Atlantic, and analyzed for bromoanisoles (BAs) and methoxylated bromodiphenyl ethers (MeO-BDEs). Target compounds were quantified by gas chromatography-low re

Diet and biliary tract cancer risk in Shanghai, China.

Trends in biliary tract cancer incidence rates have increased in Shanghai, China. These trends have coincided with economic and developmenta … bladder cancer (OR: 0.81, 95% CI: 0.68-0.97). Similar trends were seen in the food group containing seaweed and kelp (OR: 0.79, 95% CI: 0.67-0.96). In contrast, both preserved vegetables and salted meats food groups showed positive associations with gallbladder cancer (OR:1.27, 95% CI: 1.06-1.52; OR: 1.18, 95% CI: 1.02-1.37, respectively). Each of these f …

Immunotherapeutic and Antitumoral Potential of Fatty Acids from Subantarctic Macroalgae (Sarcopeltis skottsbergii).

Immunotherapy has emerged as a pivotal approach in cancer treatment, harnessing the body's immune system to recognize and eradicate tumor cells. The search for novel compounds that can enhance immune responses while selectively targeting cancer cells remains a significant area of research. This study investigates the immunotherapeutic and antitumoral potential of fatty acids derived from the subantarctic red macroalgae Sarcopeltis skottsbergii. The cytotoxic effects of these fatty acids were evaluated in vitro using HCC1954 (breast cancer), HL-60 (leukemia), and CHO (non-tumoral) cell lines. R

Interleukin 10 and hydrogen peroxide mediate anti-allergic activity of polysaccharide from Pyropia yezoensis f. narawaensis.

In recent years, anti-allergic effects of food factors have been attracting attention as a treatment for allergic diseases with fewer side effects. Previous study demonstrated that oral administration of the polysaccharide from Pyropia yezoensis f. narawaensis (PPY) to mice improved allergic responses, and that the suppressive effect involved an increase in IL-10 secretion into the blood. However, it was not clear how IL-10 secretion was related to the anti-allergic activity of oral administration of PPY. The aim of the present study was to investigate the mechanism of anti-allergic effect of

Identification of contaminants of concern in the upper Tagus river basin (central Spain). Part 2: Spatio-temporal analysis and ecological risk assessment.

This study provides a description of the water quality status in the tributaries of the upper Tagus River and a preliminary risk assessment for freshwater organisms. A wide range of physico-chemical parameters, nutrients, metals and organic contaminants (20 pesticides, and 32 point source chemicals, mainly pharmaceuticals) were monitored during spring, summer and autumn of 2016. Monitoring of organic contaminants was performed using conventional grab sampling and passive samples (POCIS). The variation of the different groups of parameters as regards to land use and sampling season was investig

Comparison of clinical characteristics and dietary intakes according to phenotypes of type 2 diabetes mellitus in South Korea: a cross-sectional study.

OBJECTIVES: Clinical nutrition treatment is the central part of diabetes management, such as prevention, treatment, and self-management of d … me of eating out and a high intake of vitamin C, and iodine because of the intake of vegetables and seaweeds. CONCLUSION: We observed differences in diet, nutrient intake, and clinical characteristics according to the phenotype of T2DM patients. In particular, obese diabetes patients have an increased risk of cardiovascular diseases, bad dietary habits, …

Устранение неврологических расстройств путем борьбы с нейродегенеративными ассоциированными ферментами: естественные и синтетические молекулы.

Неврологические расстройства, включая нейродегенеративные и нейро-воспалительные заболевания, создают значительные проблемы в области здравоохранения и клинических проблем. Недавние исследования показали, что различные ферменты играют ключевую роль в наступлении и развитии этих расстройств. В этом обзоре изучается терапевтический потенциал адресации этих ферментов естественными и синтетическими молекулами. К таким заболеваниям, как болезнь Альцгеймера, болезнь Паркинсона и множественный склероз, причастны основные ферменты, включая ацетилхолинестеразу, оксидазу моноамина, бета-секретазу, тау к

Совпадение в аннотации оригинала
Neurological disorders, encompassing neurodegenerative and neuroinflammatory conditions, present significant public health and clinical chal … ease progression, or reverse pathological changes. Natural molecules derived from plants, microbes, seaweeds, and animals have long been noted for their therapeutic potential. Their ability to interact with specific enzymes with high specificity and minimal side effects makes them promising candidates for treatment. These natural agents provide a foundati …

Inhibitory Effect of Biotransformed-Fucoidan on the Differentiation of Osteoclasts Induced by Receptor for Activation of Nuclear Factor-κB Ligand.

Bone homeostasis is regulated by constant remodeling through osteogenesis by osteoblasts and osteolysis by osteoclasts and osteoporosis can be provoked when this balance is broken. Present pharmaceutical treatments for osteoporosis have harmful side effects and thus, our goal was to develop therapeutics from intrisincally safe natural products. Fucoidan is a polysaccharide extracted from many species of brown seaweed, with valuable pharmaceutical activities. To intensify the effect of fucoidan on bone homeostasis, we hydrolyzed fucoidan using AMG, Pectinex and Viscozyme. Of these, fucoidan bio…

Assessing the effects of human activities on the foraging opportunities of migratory shorebirds in Austral high-latitude bays.

Human presence at intertidal areas could impact coastal biodiversity, including migratory waterbird species and the ecosystem services they … time spent foraging in two similar bays with contrasting disturbance levels: human presence (mostly seaweed harvesters accompanied by dogs) was on average 0.9±0.4 people per 10 ha in the disturbed bay, whereas it was negligible (95% days absent) in the non-disturbed bay. Although overall abundances were similar between bays, godwit density was higher in t …

Use of Biostimulants for Organic Apple Production: Effects on Tree Growth, Yield, and Fruit Quality at Harvest and During Storage.

The experiment was conducted during two consecutive seasons (years 2016 and 2017) in an organic apple orchard of the cultivar Jonathan. Several biostimulants were tested (10 in total), including humic acids, macro and micro seaweed extracts, alfalfa protein hydrolysate, amino acids alone or in combination with zinc, B-group vitamins, chitosan and a commercial product containing silicon. Treatments were performed at weekly intervals, starting from the end of May until mid-August. The macroseaweed extract was effective in stimulate tree growth potential in both years, as shown by a significantly…

Fucoxanthin Protects Against Acute Liver Injury by Inhibiting NOD-Like Receptor Protein 3 Inflammasome-Mediated Pyroptosis Through the Mitogen-Activated Protein Kinases and Nuclear Factor-Kappa B Pathway.

Acute liver injury (ALI) is a severe public health problem closely associated with oxidative stress, inflammation, and hepatocyte injury, leading to high mortality. Fucoxanthin (Fx), a marine carotenoid found in brown seaweeds, has various beneficial effects against multiple diseases. However, the potential role of Fx on ALI remains unclear. This study aims to explore the pharmacological potential of Fx in lipopolysaccharide (LPS)/D-galactosamine (D-Gal)-induced ALI. The therapeutic effect of Fx on ALI was primarily evaluated using a mouse model induced by LPS/D-Gal, focusing on pathological c…

Effects of probiotic fermentation on Gracilaria bailinae polysaccharides: Characterization and immunomodulatory potency.

Gracilaria bailinae polysaccharides have limited applications due to their high viscosity, large molecular weight, and poor solubility. Micr … indings provide a theoretical foundation for the development and application of probiotic-fermented seaweed polysaccharides.

Resolution-Phase Immunometabolic Reprogramming by Gelidiopsis variabilis Polysaccharides: Macrophage Polarization and In Vivo Anti-Inflammatory Efficacy.

Sulfated polysaccharides from red seaweeds are emerging as versatile bioactive macromolecules. Here, we report that funoran-type galactans from Gelidiopsis variabilis (GV) function as immunometabolic reprogrammers, orchestrating inflammation resolution through targeted remodeling of amino acid and fatty acid metabolism in macrophages, potentially via receptor-mediated pathways. Cold and hot water extraction yielded structurally distinct fractions (360-3006 kDa) characterized by NMR as sulfated galactans with κ-carrageenan motifs and variable sulfation (6.6-21.5%). In RAW264.7 macrophages, frac…

Recovery Following Harvesting of Ascophyllum nodosum Forests: Impacts on Populations and Canopy Composition.

Our overall aim was to assess the sustainability of exploitation of slow-growing, long-lived intertidal Ascophyllum nodosum forests. They ha … we demarcated two control plots and one harvest plot which was mechanically harvested by the local seaweed harvesting team. Biomass and cover of all fucoids and plant height of Ascophyllum plants were measured on shore transects from 2016 to 2021. Ascophyllum harvesting was most efficient in the middle and lower parts of its zone on the shore due to tida …

Effect of a phthalate derivative purified from Bacillus zhangzhouensis SK4 on quorum sensing regulated virulence factors of Pseudomonas aeruginosa.

Pseudomonas aeruginosa causes life-threatening diseases and is resistant to almost all conventional antibiotics. The quorum sensing (QS) system of P. aeruginosa contributes to many pathogenic factors some of which are pigment production, motility, and biofilm. The disruption of quorum sensing system may be an impactful strategy to deal with infections. The present study investigates the anti-quorum sensing property of a bioactive molecule extracted from marine epibiotic bacteria present on the surface of seaweeds. Among all the isolates tested against monitor strain Chromobacterium violaceum (…

Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-α/IFN-γ- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway.

Recent studies have revealed that marine brown seaweeds contain numerous bioactive compounds which exhibit various bioactivities. The present study investigated the effect of low molecular weight fucoidan (SCF) isolated from Sargassum confusum, a brown alga, on inflammatory responses and oxidative stress in HaCaT keratinocytes stimulated by tumor necrosis factor (TNF)-α/interferon (IFN)-γ. SCF significantly increased the cell viability while decreasing the intracellular reactive oxygen species (ROS) production in TNF-α/IFN-γ-stimulated HaCaT keratinocytes. In addition, SCF effectively reduced …

Phycochemical and Biological Activities From Different Extracts of Padina antillarum (Kützing) Piccone.

Seaweeds are non-vascular, photosynthetic that inhabit the coastal regions commonly within rocky intertidal or submerged reef-like habitats and have been one of the richest and most promising sources of bioactive primary and secondary metabolites with antimicrobial properties. They selectively absorb elements like Na, K, Ca, Mg, I, and Br from the seawater and accumulate them in their thalli. Padina antillarum (Kützing) Piccone is a member of Phaeophycota and has remarkable phycochemistry as well as bioactivity. The phycochemical tests of the different extracts showed the presence of alkaloids…