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Sydenham Chorea in Sudan; Presentation Panorama.

INTRODUCTION: Sydenham's chorea (SC) is the most common form of acquired chorea in childhood, it is considered a neurological complication of streptococcal pharyngitis. In this study, we aimed to determine the clinical pattern, association of Sydenham's chorea with other manifestations of acute rheumatic fever, and the laboratory findings of Sydenham's chorea among Sudanese patients. METHODS: A prospective cross-sectional study involving fifty patients of various ages diagnosed with Sydenham's chorea and followed up at The National Center for Neurological Sciences from January 2017 to Novembe…

External strangulated hernia in Khartoum, Sudan.

OBJECTIVES: To determine the pattern of presentation and outcome of strangulated external hernia, to predict the risk factors of strangulation, and to draw the attention towards the incidence of strangulation and its sequelae which are preventable by early repair. DESIGN: A prospective study over a two year period. SETTING: Khartoum Teaching Hospital, Casualty Department during the period May 2002 to May 2004. SUBJECTS: Sixty four patients with strangulated external hernias. RESULTS: The mean age was 42 years and the age range was between 0.5-72 years. The male: female ratio was 5:1 and ma

Визуальная потеря на постконфликтном юге Судана.

Бьючан обсуждает два исследования на юге Судана, в которых приводятся первые оценки распространенности и причин слепоты и слабовидения в этом регионе с момента начала 21-летнего конфликта.

Совпадение в аннотации оригинала
Buchan discusses two studies in southern Sudan that provide the first estimates of the prevalence and causes of blindness and low vision for this region since before the 21-year conflict began.

Blinding trachoma in postconflict southern Sudan.

BACKGROUND: Trachoma is a leading cause of preventable blindness. Reports from eye surgery camps and anecdotal data indicated that blinding trachoma is a serious cause of visual impairment in Mankien payam (district) of southern Sudan. We conducted this study to estimate the prevalence of trachoma, estimate targets for interventions, and establish a baseline for monitoring and evaluation. METHODS AND FINDINGS: A population-based cross-sectional survey was conducted in May 2005. A two-stage cluster random sampling with probability proportional to size was used to select the sample population. …

Yellow fever outbreak, Imatong, southern Sudan.

In May 2003, the World Health Organization received reports about a possible outbreak of a hemorrhagic disease of unknown cause in the Imatong Mountains of southern Sudan. Laboratory investigations were conducted on 28 serum samples collected from patients in the Imatong region. Serum samples from 13 patients were positive for immunoglobulin M antibody to flavivirus, and serum samples from 5 patients were positive by reverse transcription-polymerase chain reaction with both the genus Flavivirus-reactive primers and yellow fever virus-specific primers. Nucleotide sequencing of the amplicons obt…

Visceral leishmaniasis in Sudan. Clinical features.

Kala azar is a disease endemic to the Sudan and a cause of major morbidity and mortality to affected patients when the diagnosis or treatment has been delayed. In this report we described the clinical features of 99 parasite proven patients with visceral leishmaniasis. The Sudanese kala azar patient is young in age (teens to 20's), has marked weight loss despite a continuous, excellent appetite and suffers from insomnia, epistaxis and abdominal pain. Hepatosplenomegaly is universally present. Generalized lymphadenopathy is a prominent feature (72%). The high prevalence of lymphadenopathy has a…

Sudan virus disease - A quick review.

The recent Sudan virus disease (SVD) outbreak in Uganda is a reminder of threat from Filovirus diseases. Unlike Ebola virus disease, no effective antiviral and vaccine is available for SVD. The outbreak was declared over after 115 days, with 142 confirmed cases and case fatality rate of 39%, before any dose of candidate vaccine could be used on contacts. We provide a quick review of up-to-date information on the Uganda outbreak, summary of previous outbreaks, and detail the existing SVD treatment and vaccine candidates. Evolution of disease attributes and the impact on public health were also …

Childhood cancer in Sudan: 1999-2007.

There is paucity of information on childhood cancer from Sudan with the last studies published more than 20 years ago. This study aims to provide a current picture of childhood cancer in Sudan. Data was obtained from the hospital registry for the period May 1999 to June 2007 on all paediatric patients presenting to the Institute of Nuclear Medicine and Oncology, University of Gezira, Wad Madani, Sudan. There were 322 children with cancer during this time period with a male:female ratio of 1.6:1. Lymphomas (111, 35%), leukaemia (83, 26%) and Wilms' tumour (43, 13%) were the three most common gr…

Yellow fever outbreak, southern Sudan, 2003.

In May 2003, an outbreak of fatal hemorrhagic fever, caused by yellow fever virus, occurred in southern Sudan. Phylogenetic analysis showed that the virus belonged to the East African genotype, which supports the contention that yellow fever is endemic in East Africa with the potential to cause large outbreaks in humans.

Measles in Equatoria region--south Sudan.

A retrospective analysis of 208 cases of measles admitted to Sabbah Children's Hospital, Juba is presented. Seventeen per cent of the children were less than 10 months of age. The overall case fatality rate was 23%. The death rate was lowest in the first 9 months of life and increased with age, as did the incidence of malnutrition. It is recommended that measles vaccination should commence at 6 months of age in the Juba area, and that intensive health education about the dangers and management of measles be instituted.

Chronic renal failure in Khartoum, Sudan.

A study of the clinical presentation and conceivable causes of chronic renal failure (CRF) in 61 Sudanese patients in Khartoum is presented. The clinical features involved almost all the systems, however, gastrointestinal and cardiovascular signs and symptoms predominated. The causes of chronic renal failure in Sudan and Sweden are also studied for comparison. The causes of CRF in Sudan are chronic glomerulonephritis, obstructive nephropathy (stone disease), hypertension and diabetes mellitus in that order. The main causes of CRF in Sweden are chronic glomerulonephritis, diabetes mellitus and …

Screening hemodialysis patients for tuberculosis in Sudan.

OBJECTIVES: To estimate the prevalence of latent tuberculosis infection (LTBI) and the need for TB preventive treatment (TPT) among hemodialysis (HD) patients in Sudan. METHODS: We screened patients in a single HD center by two-step tuberculin skin test (TST), symptom survey, physical examination and chest radiography (CXR). RESULTS: The survey included 204 patients, five of whom (2.5%) had history of previously treated TB. The proportion of TST positive patients was 12.3% after the first test and increased to 21.1% after the second test. Patients previously treated for TB were more likely t…

Modelling the spatial distribution of mycetoma in Sudan.

BACKGROUND: Mycetoma is a neglected tropical disease that is reported worldwide and Sudan has the highest reported number of mycetoma infections across the globe. The incidence, prevalence and burden of mycetoma globally are not precisely known and its risk factors remain largely unelucidated. METHODS: This study aimed to identify the environmental predictors of fungal and bacterial mycetoma in Sudan and to identify areas of the country where these niche predictors are met. Demographic and clinical data from confirmed mycetoma patients seen at the Mycetoma Research Centre from 1991 to 2018 we…

An atlas of tsetse and bovine trypanosomosis in Sudan.

BACKGROUND: After a long period of neglect, initiatives are being implemented in Sudan to control tsetse and trypanosomosis. Their planning, execution and monitoring require reliable information on the geographic distribution of the disease and its vectors. However, geo-referenced and harmonized data at the national level are lacking, despite the fact that a number of epidemiological studies were conducted over the years. The Atlas of tsetse and bovine trypanosomosis in Sudan tries to fill this gap. METHODS: The present study includes both a review of historical datasets on tsetse flies and b…

Identification of congenital rubella syndrome in Sudan.

BACKGROUND: Epidemiological data about congenital rubella syndrome (CRS) are scarce and rubella vaccine is not yet included in the childhood immunization schedule in Sudan. This study aimed to identify and describe CRS cases among Sudanese infants with congenital eye or heart defects. METHODS: Between February and September 2010, paired oral fluid and dried blood spot samples were collected from 98 infants aged up to 12 months. These infants were enrolled during their visits to five hospitals in Khartoum, Sudan. Clinical samples were screened for rubella IgM and for ≥ 6 months old infants als…