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Measles in pregnancy: a threat for Italian women?

Measles in pregnancy may lead to serious sequelae for newborns and mothers. In Italy assessment of immunity against measles is not recommended as pregnancy screening. This study aimed to assess the immunity against measles in pregnant women from Apulia Region in Southern Italy between 2016 and 2017. Overall, 96.9% of pregnant women were positive for anti-measles IgG, younger women aged 19-29 years had a seroprevalence below 90%. No samples were positive for anti-measles IgM. In conclusion, younger pregnant women showed to be at higher risk of contracting measles during pregnancy. These finding…

Global landscape of measles and rubella surveillance.

BACKGROUND: All six World Health Organization (WHO) regions have committed to eliminate measles, and three WHO regions have committed to eliminate rubella. One of the key tenets of measles and rubella elimination is to have a strong surveillance system in place. The presence of a case-based measles and rubella surveillance system that is national, population-based, provides laboratory confirmation, and directs action, is one of the requirements for elimination-standard surveillance. METHODS: In order to understand the global landscape for measles and rubella surveillance, a questionnaire was …

Measles: a disease often forgotten but not gone.

Measles (rubeola) is a highly contagious vaccine-preventable disease caused by the measles virus-a virus of the Paramyxoviridae family. The illness typically begins with fever, runny nose, cough, and pathognomonic enanthem (Koplik spots) followed by a characteristic erythematous, maculopapular rash. The rash classically begins on the face and becomes more confluent as it spreads cephalocaudally. Laboratory confirmation of measles virus infection can be based on a positive serological test for measles-specific immunoglobulin M antibody, a four-fold or greater increase in measles-specific immuno…

A Rare Coincidence of Measles with Typhoid Fever.

Typhoid, otherwise known as enteric fever, and measles both have a high incidence worldwide. However, a coincidence of both has been only documented twice previously in 1866 and 1949. We present a case of a 24-year-old male who presented with high-grade fever and diffuse abdominal tenderness. He was diagnosed with typhoid initially, but during the course of his illness, he developed a maculopapular rash and pathognomonic Koplik's spots. Further investigations confirmed measles that was concurrent with typhoid. This highlights the importance of further comprehensive investigations even in diagn…

A Moral Imperative to Eradicate Measles, Rubella.

On Sept. 27, 2016, the Pan American Health Organization — the World Health Organization’s Americas branch — announced that measles had been eliminated in the region. It was exciting news! PAHO is the first WHO region to accomplish the task, a triumphant sequel to its 2015 announcement that, thanks to widespread vaccination, rubella (along with congenital rubella syndrome) had been eliminated in the Americas.1

Measles Lymphadenopathy in a Child With PFAPA Syndrome.

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a common cause of periodic fever in children. The pathogenesis of PFAPA is unknown but likely involves immune system dysregulation and may be initiated by an environmental trigger. Tonsillectomy resolves or improves symptoms in some patients, but the reason for this is unknown; moreover, specific abnormalities in tonsillectomy specimens from PFAPA patients have not been described. Here, we report measles virus in tonsil from a child with PFAPA. Measles-type viral cytopathic effect was discovered on hist…

Measles in Canada Between 2002 and 2013.

Background.  In 1994, Canada committed to eliminate measles by the year 2000. This report presents the epidemiology of measles in Canada between 2002 and 2013 and its implications in sustaining measles elimination. Methods.  Cases included individuals reported to the Canadian Measles and Rubella Surveillance System with confirmed measles. Results.  In Canada, 1171 cases of measles were reported between 2002 and 2013 (incidence 0.29 cases per 100 000 population). The annual number of cases ranged from 6 to 752. The majority of cases were unvaccinated (63%) or had an unknown vaccination status (…

Добавка к зинку для лечения кори у детей.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Корь по-прежнему является важной причиной детской заболеваемости и смертности во всем мире, несмотря на расширение охвата вакцинами. Цинк играет важную роль в поддержании нормальной иммунологической функции, и поэтому добавки, предоставляемые детям с дефицитом цинка, будут способствовать увеличению предложения цинка и могут снизить заболеваемость и смертность от кори. ЦЕЛИ: Оценка воздействия добавки цинка на снижение заболеваемости и смертности у детей с корью.Мы обыскали CENTRAL (2014, выпуск 5), MedLINE (1946 - 3 июня 2014), EMBASE (1974 - июнь 2014), CINAHL (1981 - и

Совпадение в аннотации оригинала
BACKGROUND: Measles is still an important cause of childhood morbidity and mortality globally, despite increasing vaccine coverage. Zinc plays a significant role in the maintenance of normal immunological functions, therefore supplements given to zinc-deficient children will increase the availability of zinc and could reduce measles-related morbidity and mor…

Prevention of measles spread on a paediatric ward.

Since measles is a highly contagious respiratory infection with significant airborne transmission risk in hospitals, effective prevention measures are crucial. After a mother accompanying her child on a paediatric ward lacking a negative pressure room was diagnosed with measles, exposed persons without evidence of immunity (documentary evidence of receiving two doses of measles-mumps-rubella vaccine) were treated with vaccination or intravenous immunoglobulin (IVIG). The interruption of transmission with these treatments was evaluated. There were 44 children and 101 adults exposed to the index…

[Measles re-emerging in the Ústí Region].

A report is given of a measles outbreak in healthcare workers and the general population that occurred in February to March in Ústí nad Labem. The source of infection was a man with a history of travel to India. The outbreak was primarily observed in the patients contacts and then spread widely to healthcare workers of the Masaryk Hospital in Ústí nad Labem. The outbreak further reached the general population including family contacts of the patients. By the end of March 2014, 171 measles cases were reported, 68 (39.8%) of which in healthcare workers. Cases we confirmed by laboratory analysis …

Antibiotics for preventing complications in children with measles.

BACKGROUND: Measles is the leading killer among vaccine-preventable diseases; it is responsible for an estimated 44% of the 1.7 million vaccine-preventable deaths among children annually. OBJECTIVES: To assess the effects of antibiotics given to children with measles to prevent complications and reduce pneumonia, other morbidities and mortality. SEARCH METHODS: We searched CENTRAL 2013, Issue 4, MEDLINE (1966 to May week 4, 2013) and EMBASE (1980 to May 2013). SELECTION CRITERIA: Randomised controlled trials (RCTs) and quasi-RCTs comparing antibiotics with placebo or no treatment, to preven…

Measles elimination goal: is it feasible for India?

OBJECTIVE: To assess whether measles elimination goal would be feasible for India or not. METHODOLOGY: Secondary review of data from WHO Regional Consultative Meet on Measles and Workshop on Rubella. Discussion with stakeholders such as UNICEF experts, PATH, and Government officials. RESULTS: The National Technical Advisory Group of India (NTAGI) has chalked out two broad strategies depending on the routine measles coverage of first dose (MCV1). In 18 states with sustained MCV1 coverage ≥80%, a second routine dose of measles would be given, whereas those states with <80% coverage, supplement…

Laboratory diagnosis of measles and rubella infection.

Current diagnostic laboratory tests were summarized. Measles outbreak was noted in Japan 2007 and large proportion of the patients was high school, college students, and adult patients, caused by D5 Bangkok type. Through molecular epidemiological study, drastic changes in circulating genotypes were demonstrated since 1984 to present, in Japan.

Otosclerosis and measles virus - association or causation?

Otosclerosis is a frequent condition which occurs exclusively in the human temporal bone. This peculiar disease affects mainly Caucasians an … xistence of otosclerosis genes (OTSC 1-5) including mutations of the collagen gene 1A1 and 1A2 or a measles virus (MV) infection were suggested. The existence of the MV proteins and RNA within the otosclerotic tissue has been shown by several authors. However, due to mainly technical problems, no further progress to elucidate the role of the virus could b …

[Measles elimination programme on the world and Poland].

Measles is still one of the leading causes of children mortality, despite of availability of a cheap, effective and safe vaccine for more than 40 years. Effective global eradication of smallpox and the success of polio eradication have provided an incentive to achieve the measles eradication all over the world. Elimination is achieved when no endemic measles cases has been observed in given area. This study analyzes epidemiological situation of measles, measles vaccination and laboratory diagnosis. In this report we describe the role of Global Measles Laboratory Network and integrated measles/…

Vaccines for measles, mumps and rubella in children.

BACKGROUND: Public debate over the safety of the trivalent measles, mumps and rubella (MMR) vaccine, and the resultant drop in vaccination rates in several countries, persists despite its almost universal use and accepted effectiveness. OBJECTIVES: We carried out a systematic review to assess the evidence of effectiveness and unintended effects associated with MMR. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 4, 2004), MEDLINE (1966 to December 2004), EMBASE (1974 to December 2004), Biological Abstracts (from 1985 to De…

Evaluation of the measles clinical case definition.

An accurate system of identifying and classifying suspected measles cases is critical for the measles surveillance system in the United States. To examine the performance of the clinical case definition in predicting laboratory confirmation of suspected cases of measles, we reviewed 4 studies conducted between 1981 and 1994. A clinical case definition was examined that included a generalized maculopapular rash, fever (>or=38.3 degrees C, if measured), and either a cough, coryza, or conjunctivitis. Serological confirmation of measles was done either by hemagglutination inhibition assay, complem…