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Efficacy of cefoxitin for the treatment of urinary tract infection due to extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates.

IntroductionCefoxitin has a good in vitro activity and stability in resistance to hydrolysis by extended-spectrum beta-lactamases and is a good candidate for the treatment of urinary tract infection. However, data are scarce regarding its use in clinical practice.MethodsWe conducted a retrospective study from September 2014 to November 2017, in a tertiary care hospital in Garches (France). We gathered all prescriptions of cefoxitin for urinary tract infection due to extended-spectrum beta-lactamase isolates. We compared the clinical outcomes between Escherichia coli and Klebsiella pneumoniae e

Move more, age well: prescribing physical activity for older adults.

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Primary hyperhidrosis: an updated review.

BACKGROUND: Hyperhidrosis (HH) is a condition characterized by excessive sweating beyond the physiological needs of thermoregulation. HH can be classified as primary (idiopathic) hyperhidrosis (PHH) or secondary hyperhidrosis (SHH), which is associated with underlying medical conditions, medications or systemic disorders. This narrative review provides an updated overview of PHH, with a focus on epidemiology, aetiopathogenesis, clinical manifestations, diagnostic approaches and current management strategies, particularly highlighting pharmacological and procedural treatment options. METHODS:

Спортивные представления в виртуальных мирах: систематический обзор спортивной имитации у неврологических паралимпийских спортсменов и неатлетических групп населения.

СВЯЗЬ: виртуальная реальность спорт-симулирования (ВР) может воспроизвести специфические для спорта ограничения в восприятии-моторе с тунцом и дополнительной обратной связью, открывая потенциальный мост от клиники до конкуренции для людей с неврологическими условиями. Мы систематически проводили оценку того, способствует ли погруженная и неимперативная спортивная имитация VR совершенствованию функции, связанной со спортом, обеспечивает ли она адекватную аэробную дозу и является ли она безопасной по сравнению с соответствующими компараторами. МЕТОДЫ: Мы проверили шесть баз данных с момента созд

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… In SCI laboratory protocols and exergame sessions (boxing, cycling), no autonomic dysreflexia or injuries were recorded; cybersickness was minimal during indoor VR cycling, with low ocular symptom scores on the VRSQ and no nausea reports, and perceived exertion remained in a submaximal range despite …

Ionic Plasticity: Common Mechanistic Underpinnings of Pathology in Spinal Cord Injury and the Brain.

The neurotransmitter GABA is normally characterized as having an inhibitory effect on neural activity in the adult central nervous system (CNS), which quells over-excitation and limits neural plasticity. Spinal cord injury (SCI) can bring about a modification that weakens the inhibitory effect of GABA in the central gray caudal to injury. This change is linked to the downregulation of the potassium/chloride cotransporter (KCC2) and the consequent rise in intracellular Cl- in the postsynaptic neuron. As the intracellular concentration increases, the inward flow of Cl- through an ionotropic GABA

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The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).

BACKGROUND & IMPORTANCE: This patient and public-involved systematic review originally focused on arachnoiditis, a supposedly rare "iatrogenic chronic meningitis" causing permanent neurologic damage and intractable pain. We sought to prove disease existence, causation, symptoms, and inform future directions. After 63 terms for the same pathology were found, the study was renamed Diseases of the Leptomeninges (DLMs). We present results that nullify traditional clinical thinking about DLMs, answer study questions, and create a unified path forward. METHODS: The prospective PRISMA protocol is pu

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… Autonomic dysreflexia can occur with injuries above T7 [ 956 – 958 ]. Bowel and bladder sphincter disturbances pose additional challenges. Resources can assist practitioners with communication of techniques and sex toys if uncomfortable with this topic [ 955 ]. …

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Резюме: 31 Европейский конгресс патологии.

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