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Mental imagery of photic stimulation provokes paroxysmal EEG activity in a photosensitive patient who self-induces seizures.

This article reports a case of a 14 year-old male photosensitive epileptic patient who was able to induce fits subjectively by the mental imagery of the effective visual stimuli. The patient underwent a comprehensive electroencephalographic (EEG) examination including hyperventilation. The basic EEG showed abnormalities. Intermittent photic (IPS) and pattern stimulations (PtnS), evoked photo and pattern paroxysmal responses (PPRs) within a wide range of frequencies for 2-50 flashes per second (fps) and 0.5-6 cycles per degree (cdp) respectively. The patient was able to reconstruct the PPRs men

An examination of levels of depression, the probability of suicide, and autistic traits in medical faculty students: A cross-sectional study.

Depression and suicide attempts are reported to be high among medical students. It has also been reported that depression, suicide attempts, … he ASQ subscale points of communication (z = -5.05, P < .001), social skills (z = -6.05, P < .001), imagination (z = -3.27, P = .001), attention shifting (z = -4.35, P < .001), and ASQ total points (z = -6.64, P < .001) were significantly higher for the participants with BDI total points above the cutoff value compared to those with BDI total points below the …

[Trauma and resilience associated with the COVID-19 pandemic in the cities of Bafoussam and Dschang in Cameroon].

INTRODUCTION: The emergence of the Covid-19 pandemic in Cameroon, as in Africa and around the world, was marked by a suddenness and unpredictability that fascinated the imagination. The considerable psychic and social repercussions of the pandemic mobilized a significant anguish of death. The sudden onset of the pandemic was followed by spectacular, high-profile deaths that fascinated the imagination, listing it in the order of traumatic events, provoking reactions of astonishment, flight and avoidance. GOAL: The objective of this study is to determine the symptomatology of post-traumatic str…

From Personal Trouble to Public Issue: Early-Onset Colorectal Cancer Among Young Latino Men.

C. Wright Mills' concept of the sociological imagination connects personal troubles to public issues. This editorial, co-authored by a sociologist, a Latino cancer survivor, and a community organizing director, applies that framework to early-onset colorectal cancer (EOCRC) among young Latino men, where molecular epidemiology and structural inequities converge. Recent genomic research identifies colibactin mutational signatures disproportionately present in EOCRC tumors, suggesting early-life microbial exposures may shape later carcinogenesis. Yet biological evidence alone cannot explain why y…

A First-in-Japanese Phase 1, Double-Blind, Placebo-Controlled, Parallel-Cohort Study of Sefaxersen, an Antisense Oligonucleotide Targeting Complement Factor B, in Healthy Participants.

Increased activity in the complement alternative pathway (AP) plays a key role in diseases such as IgA nephropathy (IgAN). This first-in-Jap … e. These findings support the inclusion of Japanese patients with IgAN in the global Phase 3 study (IMAGINATION, NCT05797610).

Laennec and the vesanias: A crossroad of medicine, philosophy, and modern psychiatry.

This article revisits a little-known lecture by René-Théophile-Hyacinthe Laennec (1781-1826), best known as the inventor of the stethoscope, … gradation, subjective experience, and the blending of pathology with normal human faculties such as imagination, emotion, and belief. He critiques the dominant anatomical paradigm, notably the views of Broussais, and advocates for a moral and observational approach to mental care. His views prefigure modern biopsychosocial models and anticipate concepts such …

Не каждый бизарский поступок - это психоз - эксклюзивное представление о навязчивых сексуальных расстройствах, имитирующих психический расстройство - доклад по делу не каждый бизаррский поступок - это психоз - Пекулярное представление о навязчивых сексуальных расстройствах, имитирующих психоз - доклад по делу

Болезни, связанные с половыми отношениями, часто являются недостаточно известными в развивающихся странах, вероятно, из-за общественного осуждения, отсутствия знаний и личного значения секса в их жизни [1]. Цифровые средства массовой информации предлагают переводимость, доступ и визуальное ясное изображение половых актов в высокой степени, что не оставляет ничего для воображения [2]. В ДСМ-5 не включены такие термины, как секс-зависимость или навязчивая сексуальность, однако такие случаи встречаются и в практике психиатрии. Многие сексуальные наркоманы имеют связанные с этим психические расстр

Совпадение в аннотации оригинала
Sex-related disorders are often underreported entities in developing countries probably due to social stigma, lack of knowledge, and the personal significance of sex in their life [1]. Digital media offers portability, access, and visually explicit depictions of sexual acts in high-definition that leave nothing to the imagination [2]. Terms like sex addictio…

Staying on course with early intervention for eating disorders: beware of dilution and drift. Comment on Downs, J. 'Redefining prevention and early intervention to include longstanding and severe eating disorders'.

In a thought-provoking opinion piece written largely from his own lived experience, James Downs calls for a 're-imagination' and broadening of the concepts, principles and practices of early intervention and prevention of eating disorders (EDs), to extend their application to the treatment of people with longstanding severe EDs. In this context, he cites the First Episode Rapid Early Intervention (FREED) model/care pathway as an exemplar of how early intervention has led to tangible improvements in clinical outcomes. He posits that the proposed broadening of concepts, principles and practice w…

Melatonin: Facts, Extrapolations and Clinical Trials.

Melatonin is a fascinating molecule that has captured the imagination of many scientists since its discovery in 1958. In recent times, the focus has changed from investigating its natural role as a transducer of biological time for physiological systems to hypothesized roles in virtually all clinical conditions. This goes along with the appearance of extensive literature claiming the (generally) positive benefits of high doses of melatonin in animal models and various clinical situations that would not be receptor-mediated. Based on the assumption that melatonin is safe, high doses have been a…

Weighing in: qualitative explorations of weight restoration as recovery in anorexia nervosa.

BACKGROUND: Anorexia Nervosa (AN) continues to capture the public's imagination, centered around physical appearance, particularly weight. Clinical conceptions of AN also emphasize weight. The objective of this study was to explore how individuals with lived AN experience thought about the role of weight in illness and recovery. METHODS: The current study employed a grounded theory approach through qualitative inductive inquiry and analysis of 150 anonymous narratives, exploring firsthand experience of AN and recovery of adult individuals, based in the United States of America. RESULTS: Indi…

A review on ergonomics evaluations of virtual reality.

BACKGROUND: Virtual reality (VR) is a combination of technologies that allow the user to interact with a computer-simulated environment with the experience of immersion, interactivity, and imagination. However, ergonomic problems related to virtual reality have adverse effects on the health and experience of users, which restrict the application of virtual reality technology. OBJECTIVE: The paper aims to provide an overview of the ergonomics evaluation of VR for further development of software and hardware of VR. METHODS: This paper describes and discusses the ergonomics issues involved in t…

Relationship between parental autistic traits and parenting difficulties in a Japanese community sample.

BACKGROUND: Previous studies have suggested an association between higher levels of parental autistic traits and negative aspects of parenti … l impaired communication and maternal poor attention switching, impaired communication, and lack of imagination were related to higher parenting difficulties, while a higher maternal level of attention to detail was associated with lower difficulties in parenting. CONCLUSIONS AND IMPLICATIONS: The findings of this study highlight the importance of focusing o …

Safety: From the Paris Morgue to Oxytocin.

On Tuesday April 21, 1896, Freud gave a lecture to the Viennese medical community arguing that "hysteria," as it was then known, was caused … he brought with him a new science-the "science" of psychoanalysis, which for all its creativity and imagination, was devoid of science. One of the core concepts that would be sacrificed was safety itself. The "reality" of safety (and thus the reality of danger) was replaced by the "phantasy" of safety (and thus the phantasy of danger). This article reexamines …

[Doomsday delusions of religious content (apocalyptic version)].

OBJECTIVE: To define psychopathological and phenomenological characteristics of the apocalyptic variant of end-world delusion with religious … sions with a predominance of delusions of perception (type I) or visual-figurative delusions of the imagination (type II), which have different duration, degree of dominance and depth of psychopathological disorders.

Bad Chemistry: Basilisks and Women in Paracelsus and pseudo-Paracelsus.

The basilisk of the pseudo-Paracelsian De natura rerum is the evil twin of the homunculus. Created from menstrual blood by artificial ectoge … ge mirrors, the genuine Paracelsus links contagious disease to the deleterious action of the female imagination. Second, because the basilisk was traditionally held to be the product of an unnatural birth, being born from an egg laid by a rooster and incubated by a toad, the Paracelsian corpus frequently invokes the monster as a model for unnatural generation …

Central neuropathic pain in paraplegia alters movement related potentials.

OBJECTIVES: Spinal Cord Injured (SCI) persons with and without Central Neuropathic Pain (CNP) show different oscillatory brain activities during imagination of movement. This study investigates whether they also show differences in movement related cortical potentials (MRCP). METHODS: SCI paraplegic patients with no CNP (n = 8), with CNP in their lower limbs (n = 8), and healthy control subjects (n = 10) took part in the study. EEG clustering involved independent component analysis, equivalent current dipole fitting, and Measure Projection to define cortical domains that have functional modul…

Cardiac sympathetic denervation 100years later: Jonnesco would have never believed it.

One hundred years have elapsed since Thomas Jonnesco performed the first left cardiac sympathetic denervation (LCSD) in a patient with unmanageable angina pectoris and ventricular tachyarrhythmias, and the progress in the field has surpassed imagination. Here we will review the historic basis of cardiac sympathectomy for the management of life-threatening arrhythmias and will then discuss the often forgotten critical experimental studies that provided the rationale for the amazing growth of its role in clinical management. We will then mention the evolution in the surgical approaches, with the…

A functional magnetic resonance imaging study of visuomotor processing in a virtual reality-based paradigm: Rehabilitation Gaming System.

The Rehabilitation Gaming System (RGS) has been designed as a flexible, virtual-reality (VR)-based device for rehabilitation of neurological … al magnetic resonance imaging of 18 right-handed healthy subjects (24 ± 3 years) in both active and imagination conditions. We observed that the imagery of target catching was related to activation of frontal, parietal, temporal, cingulate and cerebellar regions. We interpret these activations in relation to object processing, attention, mirror mechanisms, an …

Early manifestations of autism spectrum disorders. Experience of 393 cases in a paediatric neurology.

INTRODUCTION: Autism spectrum disorders are group of conditions characterised by qualitative impairments in social communication, interaction, and imagination, and by a restricted range of interests and typical repetitive behaviours. Frequently, there is a delay in the age of detection, and therefore in starting multidisciplinary evaluations and interventions, which may result in a poorer prognosis and reduced quality of life for both children and parents. The aim of our study was to describe clinical and epidemiological data including the age of detection and main initial complaints present i…