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Extensive surveillance of mosquitoes and molecular investigation of arboviruses in Central Iran.

BACKGROUND: Arboviruses are one of the greatest threats to animal and public health. Culicidae family is one of the most important vectors for the transmission of arboviruses in the world. According to the geographical, demographic, and climatic features of Qom city in Iran, it can be a suitable region for vectors and therefore transmission of arboviruses. METHODS: In this study, which was conducted between 2019 and 2020 in different parts of Qom city, 83 414 mosquitoes were collected, and after evaluating the species of mosquitoes based on morphological and molecular detection, the presence …

Prevalence of Coxiella burnetii in unpasteurized dairy products in west of Iran.

Q fever is a zoonotic disease caused by Coxiella burnetii. This study investigated the prevalence of C. burnetii in traditional dairy products, specifically yogurt and cheese, in Lorestan Province. A total of 100 samples of traditional yogurt and unpasteurized cheese were collected from various regions. To analyze the genome of C. burnetii, DNA was purified and molecular detection was performed using nested PCR with primers specific to the IS1111 transposon gene. The results revealed a prevalence of 13.3 % (95 % CI: 6.9 %-24.16 %) in yogurt samples and 12.5 % (95 % CI: 5.46 %-26.11 %) in chees

Сероэпидемиология хронического токсоплазмоза у пациентов с множественным склерозом в северо-восточном Иране.

КОЛИЧЕСТВО: Токсоплазма гонди — общий внутриклеточный паразит, связанный с хроническими инфекциями, который может способствовать патогенезу множественного склероза (MS). Потенциальная роль Т. Гонди в инициировании или усилении нейро-воспалительных процессов была предложена в ряде недавних исследований. Мы стремились оценить распространенность антител T. gondii IgG у пациентов MS по сравнению с здоровыми людьми и оценить связанные с ними демографические, экологические и жизненные факторы риска. МЕТОДЫ: В рамках этого перекрестного тематического исследования в Центре комплексной MS больницы Гхем

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BACKGROUND: Toxoplasma gondii is a common intracellular parasite implicated in chronic infections that may contribute to the pathogenesis of … this cross-sectional case-control study at the Comprehensive MS Center of Ghaem Hospital, Mashhad, Iran, 99 MS patients and 92 matched healthy controls were enrolled. Serum samples were tested for T. gondii IgG using ELISA, and data on demographics, pet ownership, diet, untreated water consumption, COVID-19 history, and MS symptoms (muscle weakness, b …

Prevalence of cataracts in Iran based on the Persian eye cohort study.

The PERSIAN eye cohort study is a population-based study that evaluates the overall prevalence of cataracts and their subtypes (nuclear sclerosis, cortical, and PSC) in Iran. In this study, from January 2015 to September 2021, 16,016 participants over 35 years of age from four provinces who were selected by random cluster sampling were examined. Demographic information, education, socioeconomic status, and place of residence were collected through interviews. The cataract status of the study participants was examined by two experienced ophthalmologists using slit lamp photography. The average …

Risk Factors for Retinopathy of Prematurity in Preterm Infants in Kerman, Iran.

PURPOSE: Retinopathy of prematurity (ROP) is the main cause of blindness in premature infants. Despite developments in neonatal care and management guidelines, ROP is becoming increasingly prevalent worldwide. Hence, the identification of risk factors for ROP is critical to diminish the burden of the disease. METHODS: This cross-sectional study included all infants with gestational age ≤ 36 weeks referred to the ophthalmology clinic at Shafa hospital, Kerman, Iran from 2014 to 2015. Ophthalmologic examinations were performed followed by demographic and ophthalmic data collection and analysis.…

Sensory neuropathy in patients with Pompe disease: a case series in Iran.

BackgroundPompe disease is a glycogen storage disease primarily affecting striated muscles. Despite its main manifestation in muscles, patients with Pompe disease may exhibit non-muscle symptoms, such as hearing loss, suggesting potential involvement of sensory organs or the nervous system due to glycogen accumulation.AimsThis study aimed to evaluate the presence of concomitant small and large fiber neuropathy in patients with Pompe disease.MethodsIn this case series study, nine patients with Pompe disease without complaints of neuropathy were evaluated. Small fiber neuropathy was assessed usi

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… Methods Study design This case series recruited patients diagnosed with Pompe disease who underwent Enzyme Replacement Therapy (ERT) at a teaching hospital in Tehran, Iran, from March 2021 to December 2021. … Among the 31 living patients with Pompe disease registered for treatment in Iran, nine patients were ultimately included in the study following evaluation for exclusion criteria, including a medical history of polyneuropathy risk factors (Table 1 ). …

Estimating avoidable burden of stillbirth attributable to greenness improvement in Iran.

INTRODUCTION: Expanding evidence suggests beneficial impacts of greenspace on human health, yet the relationships between greenness and stillbirth remain unknown. This study aimed to quantify the risk and burden of stillbirth associated with maternal greenness exposure during pregnancy. METHODS: A total of 3,982,304 eligible birth records across 31 provinces in Iran from 2013 to 2018 were included in this study. Greenness exposure during pregnancy was assessed using the satellite-based normalized difference vegetation index (NDVI) and enhanced vegetation index (EVI) with multiple buffers. Sti…

Molecular epidemiology of dermatophytosis in Golestan, Iran: A cross-sectional study.

Keratinophilic fungi, or dermatophytes, are recognized as the predominant fungal agents responsible for superficial skin diseases globally. The identification of species of dermatophytes is crucial for both therapeutic and epidemiological considerations. The primary objective of the present study was to investigate the epidemiology of dermatophytosis among patients who sought medical attention at the medical mycology laboratory in Golestan province. This study aims to provide a comprehensive assessment and analysis of fungal infections occurring in many anatomical regions of the human body and

The Impact of COVID-19 on Trauma Emergency Patients in Southeastern Iran.

OBJECTIVE: With the COVID-19 outbreak in countries around the world, the countries' healthcare systems underwent an unprecedented shock. This study aimed to examine the resilience of the medical service delivery system in providing emergency services during the Covid-19 pandemic. METHODS: This study was conducted in a reference hospital in Kerman that provided emergency services to trauma patients. It compared service delivery before and after COVID-19, as well as during the COVID-19 peak and non-peak periods. The compared variables were the number of trauma patients admitted to the hospital

A Case Report of Thoracic Ectopia Cordis in a Hospital in Zanjan, Iran.

METHODS: A 17-week-old female neonate with a history of prenatal diagnosis of congenital heart anomaly was admitted to Ayatollah Mousavi Hospital in Zanjan, Iran. For the diagnosis of thoracic ectopia, cordis fetal echocardiography and ultrasonography were performed. Moreover, the noninvasive prenatal testing (NIPT) genetic test performed in the 10th week of pregnancy was evaluated. RESULTS: The neonate was diagnosed with thoracic ectopia cordis, with the heart located outside the thoracic cavity and covered by a thin membrane. The Z scores of the analyzed maternal venous blood chromosomes we…

The first case of Mpox infection in Iran during the 2022 outbreak.

INTRODUCTION: The unexpected outbreak of human Mpox infection beginning in some European countries that were non-endemic for Mpox stunned the world during the Coronavirus Disease 2019 (COVID-19) pandemic in May 2022. The re-emerging Mpox outbreak, which has a greater capacity for human-to-human transmission, was mainly due to traveling. In this paper, we describe the first case of the disease was observed in an Iranian woman infected by her husband who had a history of traveling to Canada. CASE REPORT: The 34-year-old woman had flu-like syndrome with some skin rashes on her hand, finger, and …

Endocarditis Caused by Coxiella burnetii: A Case Report in Western Iran.

BACKGROUND: Q fever is a contagious zoonotic disease which is caused by a gram-negative and intracellular Coccobacillus known as Coxiella bu … -transmitted pathogen that has been known as an important cause of culture-negative endocarditis in Iran, and more attention needs to be paid to this disease in Iran by the healthcare system and physicians.

Treatment Options of Maxillofacial Fractures in Iran: A Comprehensive Systematic Review.

BACKGROUND: The aim of this study was to systematically review the literature on the treatment options of maxillofacial fractures in Iran, complementing a previous article regarding causes and the overall prevalence. METHODS: A systematic search of PubMed, Cochrane Library, Web of Science (WS) and Google Scholar (GS) electronic databases was conducted to identify the relevant articles published up to January 2023. Studies reporting the treatment option of maxillofacial fractures in Iran were included in the analysis. MOOSE guidelines were adopted for the current systematic review. No data or …

Evaluation of iron content in bakery flour samples of Tehran, Iran.

Given that iron-deficiency anemia is a major nutritional problem in Iran and bread is one of the main foods in Iranian household basket, a flour fortification program with iron was established in 2001. Thereafter, to quality control of the mentioned program, the iron concentration was measured in flour samples. Accordingly, this study was conducted to investigate the iron content in wheat flour samples in Tehran, Iran. One hundred and twenty-one samples of wheat flour (i.e., Confectionery, Taftoon, Setareh, Barbary, Sangak wheat flour) were randomly collected from bakeries in Tehran by simple …

Effect of local anesthetics on renal function: An animal study in Iran.

BACKGROUND: Although most of the metabolism of local anesthetics (LAs) takes place in the liver, no study has investigated the effect of these anesthetics on the kidney function of single-kidney humans or animals. The present study was conducted to examine the effect of LAs on renal function in single-kidney rats. MATERIALS AND METHODS: The present experimental animal study with two control groups was done in an animal laboratory. Forty-two rats were randomly assigned to seven groups of six rats, including two control groups and five experimental groups. The experimental groups underwent intr

Experience of individuals with unconsummated marriage in Iran: A qualitative content analysis.

BACKGROUND: Sex is one of the important aspects of marriage and a way of expressing intimacy. Unconsummated marriage is a common problem whose prevalence is about 1.5% in Iran and can significantly influence marital life. OBJECTIVE: This study aimed to assess the unconsummated marriage in a qualitative mode to offer new and beneficial solutions resulting from a better understanding. MATERIALS AND METHODS: In this qualitative study, conventional content analysis was used. Data collection and analysis were done from April 2013 to April 2014 with 11 women and 5 men participating, who were refer…

Drug Utilization Evaluation of Erythropoietin at a Referral Teaching Hospital in Iran.

OBJECTIVES: Drug utilization evaluation (DUE) studies aim to survey the appropriateness of drug use. DUE is an executive approach used to improve the use of medications as well as reduce the cost of treatment, ensure drug adequacy, and improve patient safety. The aim of this study was to evaluate the pattern of erythropoietin use, according to standard guidelines, in patients admitted to Namazi Hospital in Shiraz, Iran. METHODS: In this descriptive, retrospective study, 230 patients were assessed. All patients who were hospitalized in different wards of Namazi Hospital, affiliated to Shiraz U…

Identification of High-Yielding Genotypes of Barley in the Warm Regions of Iran.

One of the most important effects of climatic changes is increasing temperatures and expanding water deficit stress in tropical and subtropical regions. As the fourth most important cereal crop, barley (Hordeum vulgare L.) is crucial for food and feed security, as well as for a sustainable agricultural system. The present study investigates 56 promising barley genotypes, along with four local varieties (Norooz, Oxin, Golchin, and Negin) in four locations to identify high-yielding and adapted genotypes in the warm climate of Iran. Genotypes were tested in an alpha lattice design with six blocks…

Polypharmacy Pattern in Iran: A Comprehensive Analysis of a Large Prescription Database.

BACKGROUND: Polypharmacy is a significant patient safety concern. OBJECTIVES: This study aims to estimate the prevalence of polypharmacy, its continuity and associated factors, and common medication classes among a large outpatient population in East Azerbaijan province, Iran. METHODS: A retrospective prescription data analysis was performed. The cohort included all ≥ 20 years old subjects with at least one prescription filled during the main three-month study period (2020 March 1 - 2020 May 31). Polypharmacy was defined as being exposed to more than four different medications during the mai…