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Sustained postoperative elevation of ionized magnesium levels following cardiac surgery with magnesium-enriched cardioplegia: a prospective observational study.

This study aimed to clarify perioperative changes in ionized magnesium levels (iMg), a physiologically active fraction, and particularly the persistence of hypermagnesemia at the time of extubation in cardiac surgery using magnesium-enriched cardioplegia. We conducted a prospective observational study of 48 patients undergoing elective cardiac surgery. iMg was measured at three time points: induction of anesthesia, intensive care unit (ICU) admission, and extubation. The median duration of postoperative mechanical ventilation was 17 h. iMg increased markedly to 1.49 [1.23-1.85] mmol/L at ICU a…