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Chagas' disease: a model of denervation in the study of digestive tract motility.

The enteric nervous system (ENS) is an important neural network that integrates, modulates and coordinates various motor functions of the di … he motor alterations caused by impairment of the digestive tract in Chagas' disease are: absence of peristalsis in the esophagus, achalasia of the cardia, loss of the accommodation reflex in the proximal stomach, gastric emptying disorders, changes in the migrating motor complex (MMC), disappearance of postprandial motor phenomena in the colon and rectum, lac …

Manometric findings during spontaneous chest pain in patients with presumed esophageal "spasms".

Nine patients with intermittent chest pain thought clinically to be secondary to esophageal "spasms" developed typical pain while being studied with an intraluminal transducer probe placed in the distal esophagus. Manometric changes from control periods were examined preceding and during pain episodes. No significant difference in distal esophageal wave duration or amplitude or in frequency of abnormal peristalsis was observed preceding or during pain episodes when compared with nonpain periods over a mean monitoring time of 227 min. No change from the nonpain periods in esophageal baseline pr…

[Diagnosis of the functioning of an interposed part of the colon substituting part of the oesophagus after oesophageal resection (author's transl)].

In 6 patients with carcinoma of the oesophagus, resection of the oesophagus was performed, followed by substitution of part of the oesophagu … to the interposed part in horizontal position of the patient and in head down position. 4. Loss of peristalsis of the interposed part of the colon while preserving the natural sacculation and width of lumen. The findings correlated clearly with the signs and symptoms reported by the patients, such as heartburn, belching and retrosternal pain. Comparison of f …

[Familial syndrome combining short small intestine, intestinal malrotation, pyloric hypertrophy and brain malformation. 3 anatomoclinical case reports].

Anatomoclinical study of 3 cases of an exceptional malformative condition characterized by: --extreme shortness of the small intestine, --mesenterium commune, --hypertrophic pylorus, --malformation of the central nervous system (heterotopia, absence of operculum temporale). Clinically this malformative condition is characterized by failure and inertia of the intestinal peristalsis producing at intervals of 10-15 days episodes of subocclusion, the repetition of which causes death. The syndrome is familial and seems to be of autosomal recessive inheritance. The absence of mechanical obstruction,…

Esophagogastroduodenoscopy findings that do no not explain dysphagia are associated with underutilization of high-resolution manometry.

In patients with dysphagia that is not explained by upper endoscopy, high-resolution esophageal manometry (HRM) is the next logical step in … 29.7% were diagnosed with a disorder of esophagogastric junction outflow, 17.6% with a disorder of peristalsis, and 2.0% with both disorders of esophagogastric outflow and peristalsis. The diagnosis made by HRM was similar among those who had incidental EGD findings that were non-diagnostic for dysphagia compared with those who had completely normal EGD find …

Achalasia cardia: A case report in young female.

KEY CLINICAL MESSAGE: This case emphasizes the need for early recognition and accurate diagnosis of achalasia in young adults to avoid exace … esophageal sphincter (LES), leading to a loss of inhibitory neurons and resulting in the absence of peristalsis with failure of LES relaxation. Its origins are multifactorial, potentially involving infections, autoimmune responses, and genetics, with equal incidence in males and females. The hallmark symptoms include progressive dysphagia for solids and liqui …

Tubal muscles determine embryo implantation site; prognosis of ectopic pregnancy at chronic functional disorders.

Mammalian oviducts contain smooth muscles and inward-facing ciliated epithelium. Muscular contractions, not ciliary beating, propel oocytes … d sole length. Smooth muscle active states: tonic contraction/relaxation and rhythmic contractions (peristalsis) are involved in ovum transport. The ovum/embryo speed is linearly correlated with the tonus of the longitudinal and/or the circular muscles of the tube. Some known bioactive substances control muscular tonus and we suppose embryo speed through the …

An analysis of operations for gastroesophageal reflux disease: identifying the important technical elements.

BACKGROUND: Better understanding of the pathogenesis of gastroesophageal reflux disease in recent years has not been accompanied by apprecia … the short gastric vessels divided), with the choice between them based on the quality of esophageal peristalsis. The 3 groups of patients were similar in age, duration of symptoms, incidence of hiatal hernia, and incidence of esophagitis. MAIN OUTCOME MEASURES: Resolution of heartburn, incidence of postoperative dysphagia, and stability of the reconstruction …

Delayed diagnosis and treatment of achalasia: a case report.

BACKGROUND: Achalasia is characterized as an esophageal motility disorder with incomplete relaxation of the lower esophageal sphincter. Achalasia can be associated with abnormal peristalsis and symptoms of dysphagia, acid reflux, and chest pain. The exact pathophysiology of achalasia remains unclear, but it is hypothesized to be due to degeneration of the myenteric plexus. CASE PRESENTATION: In this case, a 46-year-old Hispanic man presented to the emergency room with a 12-year history of progressive discomfort with swallowing solids and liquids. Due to many years of incomplete follow-up care…

A Case Report of Hirschsprung's Disease in a Neonate: Early Detection and Review of Management.

Hirschsprung's disease is a rare disease characterized by the complete absence of ganglionic cells in the colon, thereby causing loss of peristalsis movement of the bowel. Most cases are diagnosed before the age of one. Here, we present a case of a newborn baby boy who was not feeding well and then developed a distended abdomen and began bilious vomiting. Blood mucoid stools were also observed. The diagnosis of Hirschsprung's disease was confirmed through a full-thickness rectal biopsy, and the Duhamel surgical procedure was performed as a course of treatment all within the first few days of b…

The IgSF Cell Adhesion Protein CLMP and Congenital Short Bowel Syndrome (CSBS).

The immunoglobulin-like cell adhesion molecule CLMP is a member of the CAR family of cell adhesion proteins and is implicated in human congenital short-bowel syndrome (CSBS). CSBS is a rare but very severe disease for which no cure is currently available. In this review, we compare data from human CSBS patients and a mouse knockout model. These data indicate that CSBS is characterized by a defect in intestinal elongation during embryonic development and impaired peristalsis. The latter is driven by uncoordinated calcium signaling via gap junctions, which is linked to a reduction in connexin43 …

Robotic multiple sigmoid and rectal mucosa skinning in a multicentric deep infiltrating bowel endometriotic nodules: a case report.

Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of n … ter the surgery, a normal diet was quickly restored, accelerating the recovery of the physiological peristalsis and the overall recovery time.

Iatrogenic Esophageal Perforation After Laparoscopic Heller's Myotomy Treated Successfully with Endoscopic Stent: Case Report and Literature Review.

BACKGROUND Achalasia cardia is a neuro-degenerative motility disorder, which results in the loss of esophageal peristalsis along with failure of the lower sphincter to relax in response to swallowing. It is relatively rare, with a prevalence of 10 cases per 100 000 individuals. The criterion standard in the management of achalasia is laparoscopic Heller's myotomy with partial fundoplication. Esophageal perforation is one of the earliest major complications that could be managed by primary repair. However, it has been reported that esophageal perforations in achalasia cases can be managed with …

Acute Colonic Pseudo-Obstruction Following the Use of Dexmedetomidine.

Dexmedetomidine is a preferred agent for light sedation with minimal adverse effects. We report a case of acute colonic pseudo-obstruction following dexmedetomidine use in a patient with alcohol withdrawal. He was treated with benzodiazepines first to control the withdrawal symptoms, then escalated to dexmedetomidine once delirium tremens ensued. Later on, the patient developed abdominal distension and vomiting. Imaging showed dilated bowel loops and absence of peristalsis on ultrasound. Decompression with the nasogastric (NG) tube was done, with high output from the NG tube. Dexmedetomidine i…

Hydrogen Peroxide Enema-induced Proctitis in a Young Female: A Case Report.

Hydrogen peroxide is a disinfectant commonly used for cleansing superficial wounds due to its oxidizing capacity. In the past, it has also been used for the management of meconium ileus in children as the oxidizing action of hydrogen peroxide potentiates peristalsis that relieves ileus or fecal impaction. The potential dangers were unknown till Pumphrey, in 1951, described the harmful effects of its use as an enema. We present a case of a 32-year-old female who was admitted for complaints of perianal pain. She used an enema, consisting of water and hydrogen peroxide, for constipation. It impro…

Hysteroscopic Methotrexate Injection Under Ultrasonographic Guidance for Interstitial Pregnancy.

A 36-year-old woman presented with pelvic pain and vaginal blood loss and interstitial pregnancy (a single gestational sac located in the proximity of the right uterine horn, without visualization of an embryo and/or attachments inside) on 2- and 3-dimensional ultrasonographic examination. The patient was clinically stable. Her abdomen was soft with normal peristalsis; superficial and deep palpation were painless, as was decompression. With the patient under general anesthesia, an operative hysteroscopy was performed visually via ultrasound. A slow injection of methotrexate solution was pushed…

Case report of Graves' disease manifesting with odynophagia and heartburn.

Graves' disease is an autoimmune disease, which can manifest with a variety of extrathyroidal clinical syndromes like ophthalmopathy, pretib … o decrease of all clinical symptoms after 5 d of Thiamazole administration. Complete restoration of peristalsis in the esophagus, according to manometry, was observed in 1 mo after initiation of treatment.

[Hypothermal sanation in acute peritonitis].

Comparative analysis of treatment of 78 patients, suffering an acute peritonitis, was conducted for studying of practical significance of hypertonic peritoneal-enteric sanation (PES). In 40 patients (control group) the conventional methods of treatment were used and in 38 (the main group)--the treatment was conducted on the PES background. Such clinical indices, as the patient state, body temperature, respiration rate, pulse and intestinal peristalsis, while the PES application, have had normalized earlier. As well the raising of the survival capacity of an organism, suffering critical state, …

Capsule endoscopy in 2005: facts and perspectives.

Capsule endoscopy has recently been introduced to explore endoscopically the whole small intestine, fulfilling a gap between examinations of the upper and lower gastrointestinal tract. The technique consists of a miniaturized endoscope, embedded in a swallowable capsule that is propulsed by peristalsis and achieves the journey to the right colon in five to eight hours. Images captured by the capsule are recorded on a hard drive worn in a belt by the patient. The main indication for capsule examination is the examination of the small bowel to find a bleeding lesion in patients with obscure blee…

Ахалазия. Возможно, поздняя причина постполиодисфагии.

Цель этого документа состоит в том, чтобы описать пациента с серьезными постполиологическими проблемами, у которого развилась акалазия. 66-летний пациент пришел на наше наблюдение за сильной дисфагией. Он страдал парализующим полиомиелитом в возрасте 7 месяцев и имел серьезные остаточные дефициты. В возрасте 62 лет он испытывал внезапную боль при распределении дерматом С4 и С5 и неспособность похитить левую руку. В то время он испытывал лишь эпизодическую и мягкую дисфагию; его пищевод не был расширен и опустошен нормально. В последующие месяцы его мускулистая функция улучшилась, но дисфагия у

Совпадение в аннотации оригинала
The aim of this paper is to describe a patient with severe postpolio problems who developed achalasia. A 66-year-old patient came to our obs … dilatation produced good resolution of dysphagia. A year later manometry showed the reappearance of peristalsis after all wet swallows. In patients with postpolio dysphagia, the possible presence of achalasia must be considered.