Результаты поиска

Difficulty diagnosing breast cancer recurrence in the context of a radio-frequency-identification device-containing breast implant - A case report.

Concerns around the risk of prosthetic post-mastectomy breast reconstruction obscuring breast cancer recurrence existed in the early days of breast reconstruction but were laid to rest with cohort studies. We present an unusual case where MRI images were limited in diagnosing breast cancer recurrence, partly due to an artefact produced by a radio-frequency-identification device (RFID) contained within the implant. Co-existing Tietze's syndrome, an uncommon benign inflammatory condition effecting the chest wall, further confused the picture. This case highlights the diverse pathologies that can…

177Lu-FAPI-2286 Therapy in a Patient With Radio-iodine Refractory Papillary Thyroid Carcinoma: A Favorable Clinical and Biochemical Response.

We report a 38-year-old man with radio-iodine refractory papillary thyroid carcinoma (RAIR PTC) who experienced significant relief from symptoms and showed a positive biochemical response after undergoing a single cycle of 177Lu-FAPI-2286 therapy. A pretreatment 99mTc-FAPI-46 scan showed diffuse uptake throughout both lungs and subsequent serial post-treatment scans demonstrated sustained uptake in pulmonary metastases. After treatment, there was a significant decline in serum thyroglobulin levels, accompanied by a remarkable improvement in symptoms, leading to near-complete resolution. This c…

Using radio programming to reach young adolescents with gender and sexual health information in a low-income urban setting in Kenya.

BACKGROUND: Radio programs have been used to broadcast health information across Africa and beyond. However, there has been limited focus on radio programming targeting young adolescents (aged 10 - 14) with gender and sexual and reproductive health (SRH) information. An increasing body of evidence indicates a need to provide young individuals with accurate and easily accessible gender and SRH information to equip them to make well-informed choices about their SRH. METHODS: We developed an engaging and educative seven-session radio show, which featured skits and guest speakers. A local radio s…

SEEG-Guided Radio-Frequency Thermocoagulation of the Epileptogenic Networks: Its Utility for Both Treatment and Validation for Localizing Epileptogenic Networks.

INTRODUCTION: Stereoelectroencephalography-guided radio-frequency thermocoagulation (SEEG-RFTC) is a minimally invasive technique whereby radio-frequency thermocoagulation is performed using SEEG electrodes, following recording and stimulation. It helps to disconnect/disrupt or ablate the epileptogenic networks and provides both therapeutic and diagnostic abilities. METHODS: This study is a retrospective study (2016-2024). All underwent comprehensive epilepsy surgery workup (video EEG, MRI, ictal-SPECT, PET, and magnetoencephalography). SEEG was placed using robotic guidance. Recording of hab…

Analysis of the Impact of Detection Threshold Adjustments and Noise Uncertainty on Energy Detection Performance in MIMO-OFDM Cognitive Radio Systems.

Due to the capability of the effective usage of the radio frequency spectrum, a concept known as cognitive radio has undergone a broad exploitation in real implementations. Spectrum sensing as a core function of the cognitive radio enables secondary users to monitor the frequency band of primary users and its exploitation in periods of availability. In this work, the efficiency of spectrum sensing performed with the energy detection method realized through the square-law combining of the received signals at secondary users has been analyzed. Performance evaluation of the energy detection metho…

Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal Cancer.

PURPOSE: Ataxia telangiectasia mutated kinase (ATM) inhibitors are potent radiosensitizers that regulate DNA damage responses and redox metabolism, but they have not been translated clinically because of the potential for excess normal tissue toxicity. Pharmacologic ascorbate (P-AscH-; intravenous administration achieving mM plasma concentrations) selectively enhances H2O2-induced oxidative stress and radiosensitization in tumors while acting as an antioxidant and mitigating radiation damage in normal tissues including the bowel. We hypothesized that P-AscH- could enhance the therapeutic index…

Revision of cytogenetic dosimetry in the IAEA manual 2011 based on data about radio-sensitivity and dose-rate findings contributing.

In order to achieve the goal of rapid response, effective controland protection of life inlarge-scale radiation events, the IAEA Manual 2011 has been revised based on the data of radio-sensitivity, dose-rate findings. Analyze individual differences in radiation sensitivity using 60 Co radiation (0.27 Gy/min). Chromosomal aberrations with different irradiation dose rates were used to establish the biological dose curve and analyze the excess of the "dicentric + ring" caused by the dose rate at each dose point; DAPI-images and Metafer 4 were used to capture metaphase images and make further anal…

Biological Uptake, Distribution, and Depuration of Radio-Labeled Graphene in Adult Zebrafish: Effects of Graphene Size and Natural Organic Matter.

The exciting commercial application potential of graphene materials may inevitably lead to their increasing release into the environment where they may pose ecological risks. This study focused on using carbon-14-labeled few-layer graphene (FLG) to determine whether the size of graphene plays a role in its uptake, depuration, and biodistribution in adult zebrafish. After 48 h exposure to larger FLG (L-FLG) at 250 μg/L, the amount of graphene in the organism was close to 48 mg/kg fish dry mass, which was more than 170-fold greater than the body burden of those exposed to the same concentration

Системная и слизистая иммунная реакция после пероральной аденовиральной доставки вакцины против гриппа кишечнику с помощью радиоконтроля.

Существует несколько преимуществ пероральной иммунизации, включая возможность получения слизистой иммунной реакции, которая может защитить от патогенов, проникающих через мукозальную поверхность. Нашему пониманию иммунной биологии человека мешает трудность изоляции мукосальных клеток от человека и тот факт, что животные модели могут или могут не полностью отражать кишечную иммунологию человека. В этом фармакодинамическом исследовании человека была изучена новая платформа на основе векторов аденовирусов, выражающая грипп гемагглутинина. Мы использовали радиоуправляемые капсулы, чтобы доставить

Совпадение в аннотации оригинала
There are several benefits of oral immunization including the ability to elicit mucosal immune responses that may protect against pathogens … , a novel adenovirus vector-based platform expressing influenza hemagglutinin was explored. We used radio-controlled capsules to deliver the vaccine to either the jejunum or the ileum. The resulting immune responses induced by immunization at each of the intestinal sites were investigated. Both intestinal sites were capable of inducing mucosal and syste …

Efficacy of sclerotherapy with radio-opaque foam guided by digital subtraction angiography for the treatment of complex venous malformations of the head and neck.

Our aim was to evaluate the efficacy of sclerotherapy using radio-opaque foam and guided by digital subtraction angiography (DSA) for complex venous malformations in the head and neck in 11 selected patients between 2011 and 2013. The sclerosing foam was manufactured by the classic Tessari method and consisted of air, 1% polidocanol, and radio-opaque media iopromide (Ultravist(®)300) in a ratio of 7:2:1. We recorded the site and size of the lesion, time and duration of treatment, and therapeutic response. The lesions were on the face, cheek, temporal region, parotid region, neck, tongue, floor…

A radio-telemetric system to monitor cardiovascular function in rats with spinal cord transection and embryonic neural stem cell grafts.

High thoracic or cervical spinal cord injury (SCI) can lead to cardiovascular dysfunction. To monitor cardiovascular parameters, we implanted a catheter connected to a radio transmitter into the femoral artery of rats that underwent a T4 spinal cord transection with or without grafting of embryonic brainstem-derived neural stem cells expressing green fluorescent protein. Compared to other methods such as cannula insertion or tail-cuff, telemetry is advantageous to continuously monitor blood pressure and heart rate in freely moving animals. It is also capable of long term multiple data acquisit…

Measurement of colonic transit time based on radio opaque markers in patients with chronic idiopathic constipation; a cross-sectional study.

BACKGROUND: Constipation is one of the most common gastrointestinal disorders particularly in industrialized countries. Incidence of constipation varies from 3.4 % to 27.2% in different societies. Increase in urban population, industrialization of communities, changes in behavioral and nutritional habits and inactivity have increased the number of patients suffering from constipation. OBJECTIVES: The aim of the study was to measure colonic transit time in patients with chronic idiopathic constipation. PATIENTS AND METHODS: Fifty-two patients with chronic idiopathic constipation (according to

Effect of a combined surgery, re-irradiation and hyperthermia therapy on local control rate in radio-induced angiosarcoma of the chest wall.

PURPOSE: Radiation-induced angiosarcoma (RAS) of the chest wall/breast has a poor prognosis due to the high percentage of local failures. Th … Gy) and 3-6 hyperthermia treatments (mean 4). Hyperthermia was given once or twice a week following radiotherapy (RT). RESULTS: The median latency interval between previous radiation and diagnosis of RAS was 106 months (range 45-212 months). Following reRT + HT, the complete response (CR) rate was 56 %. In the subgroup of patients receiving surgery, th …

Successful treatment of venous stasis ulcers with combination compression therapy and pulsed radio frequency energy in a patient scheduled for amputation.

BACKGROUND: Venous ulcers are a frequent complication of chronic venous insufficiency. Compression therapy remains the mainstay of conservat … nd preserve his limb, Mr A underwent treatment with a combination of compression therapy and pulsed radio frequency energy. CONCLUSION: Compression therapy plus pulsed radio frequency energy led to healing of his venous leg ulcers and avoided amputation of the affected limb. This treatment is currently being evaluated in other patients with chronic ven …

The use of pulsed radio frequency energy therapy in treating lower extremity wounds: results of a retrospective study of a wound registry.

Pulsed radio frequency energy (PRFE) has been shown to stimulate cultured epidermal cells in vitro, inciting a cascade of cytokines, cyclins, growth factors, and other gene products associated with wound healing. A retrospective, descriptive study was conducted to evaluate the effect of PRFE on healing lower extremity wounds. Using data from a patient registry of 510 wounds in 413 patients, information was abstracted on patients with lower extremity wounds treated with PRFE for at least 4 weeks between 2005 and 2008 and who were evaluated 4 weeks after the start of treatment; wou…

Radio-guided thoracoscopic surgery with (99m)Tc-methoxy-isobutylisonitrile for treating an ectopic mediastinal parathyroid adenoma in an adolescent girl.

Here we report the case of a 17-year-old girl treated for an ectopic mediastinal parathyroid adenoma using (99m)Tc-methoxy-isobutyl-isonitrile (MIBI) and radio-guided thoracoscopic surgery. Her serum calcium and intact parathyroid hormone levels were elevated, and an anterior mediastinal tumor was noted on her chest computed tomography scan. At 2 h before surgery, the patient was given an injection of 370 MBq of (99m)Tc-MIBI. Because it was not possible visually to distinguish the tumor from the mature thymic tissue in which it was embedded, a search for the tumor was carried out using a gamma…

Colonic transit study by radio-opaque markers to investigate constipation: validation of a new protocol for a population with rapid gut transit.

BACKGROUND: Constipation is a common problem, which may be due to slow transit or faecal evacuation disorders. Though the screening test of colonic transit study using radio-opaque markers given at 0, 24 and 48 hours followed by abdominal X-ray at 72 hours is a good protocol in the West, it is not suitable for Indians who have a rapid gut transit. METHODS: Nine patients with adult Hirschsprung disease, 11 with chronic intestinal pseudo-obstruction diagnosed using standard investigations and 11 healthy subjects were evaluated by colonic transit study using radio-opaque markers (SGmark), 20 eac…

[Non-traumatic osteoarthritis of the distal radio-ulnar joint: a consecutive series of 11 wrists with 42 months follow-up].

PURPOSE OF THE STUDY: Non-traumatic osteoarthritis of the distal radio-ulnar joint is generally observed in a context of chondrocalcinosis and can lead to rupture of the extensor tendons. We reviewed patients operated on in our unit between 1986 and 1988 for this condition in order to examine modalities of surgical care. MATERIAL AND METHODS: Eleven patients who underwent surgery for non-traumatic osteoarthritis of the distal radio-ulnar joint were included in the study. Demographic data, clinical signs, joint amplitudes, radiologically identified lesions, peroperative macroscopic features, a…