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Phaeohyphomycosis: A 10-Year Study From a Tertiary Care Centre in South India.

Background Phaeohyphomycosis, a fungal infection caused by dematiaceous fungi, presents a significant health challenge affecting both immuno … iopsies revealed pseudoepitheliomatous hyperplasia. Among the 19 cases where culture was performed, Alternaria was the most commonly isolated pathogen (42%). Conclusion The study brings to light the diagnostic challenges inherent in phaeohyphomycosis cases, which often eluded clinical diagnosis and were only conclusively identified via pathological examinati …

[Aerobiological study in Lima, Perú. ¿Tipuana-Tipu, perhaps a new allergen?].

OBJECTIVE: To report the Tipuana tipu pollen as a new allergen capable of triggering allergic symptoms. METHODS: The pollen counts were mad … hagoides pteronyssinus, Dermatophagoides farinae, Blomia tropicalis), molds (Cladosporium herbarum, Alternaria alternata, Aspergillus fumigatus, Penicillium notatum), cat and dog danders, Periplaneta americana, grass six mix, weed mix (Inmunotek, Spain) on 80 patients (18 to 50 years old) seen in our allergy center, they suffering from november to january rh …

Age-related differences in IgE between childhood and adulthood allergic asthma: Analysis of NHANES 2005-2006.

BACKGROUND: Asthma exhibits varying clinical features in children and adults. However, previous studies have mainly focused on the clinical … did not differ between Group 1 and Group 2 but were higher compared with Group 3, particularly for Alternaria-sIgE (50.3% and 46.2% vs 15.2%) and Aspergillus-sIgE (43.9% and 37.1% vs 16.2%). In Group 1, there was a negative correlation between pollen-sIgEs and indoor allergens, but this correlation was not commonly observed in Group 2 and Group 3. On the ot …

German Environmental Survey for Children (GerES IV)--first results.

German Environmental Surveys (GerESs) are large scale population studies which have been carried out on adults in 1985/86, 1990/92 and 1998 … examined (Penicillium (notatum) chrysogenum, Aspergillus versicolor, Wallemia sebi, Eurotium spp., Alternaria alternata). The most frequent sensitisation was against Penicillium chrysogenum. GerES IV might broaden the knowledge in terms of environmental causes of health outcomes. Children of smoking mothers showed higher mean cotinine concentrations than ch …

[Update on the diagnosis of dermatomycosis].

Dermatomycosis are mycotic diseases of skin caused by a few mycetes: dermatophytes, and some opportunistic fungi as Malassezia, Candida (not C. albicans), Trichosporon, Rhodutorula, Cryptococcus or Aspergillus, Geotrichum, Alternaria, etc. Dermatophytes are a group of closely related filamentous fungi that invade keratinized tissue (skin, hair, nails) of humans and other animals and produce infection called dermatophytosis or ringworm or "tinea". The etiological agents of dermatophytosis are classified in three genera: Microsporum, Trichophyton and Epidermophyton (Deuteromycetes). On the basis…

Evaluation of topical 1% posaconazole therapy in refractory fungal keratitis.

PURPOSE: The primary objective was to evaluate the clinical response of refractory cases of fungal keratitis to topical 1% posaconazole ther … adosporium spp. were best sensitive to natamycin and PCZ, Penicillium spp. to natamycin and azoles. Alternaria keratitis isolates were sensitive to voriconazole and PCZ, whereas Rhizopus isolate was best sensitive to PCZ. CONCLUSION: Topical 1% PCZ therapy in refractory fungal keratitis was comparable to that of conventional antimycotic agents, with lower M …

Inhibition of rat parotid and submandibular gland functions by ofloxacin, a fluoroquinolone antibiotic.

Asthmatic bronchial inflammation is associated with increased nitric oxide concentrations in exhaled air (eNO). Recent data suggest that thi … e following common allergens: Dermatophagoides pteronyssinus (Dpt), cat fur, Aspergillus fumigatus, Alternaria tenuis, mixed grass, mixed tree pollen, Parietaria officinalis, egg, and cow's milk. eNO was collected in 1-l mylar bags (exhaled pressure 10 cmH2O, flow 58 ml/s) and analyzed by using chemiluminescence. Atopic and non-atopic children without a hist …

Biosynthetic pathway construction and production enhancement of phenazine-1-carboxylic acid derivatives in Pseudomonas chlororaphis H18.

BACKGROUND: Phenazines represent a promising class of natural products with diverse biological activities, including antitumor, antiparasiti … ving been reported to exhibit superior fungicidal activity against the tobacco brown spot pathogen, Alternaria alternata, compared to PCA. To enhance titers of PCM and 2-OH-PCM, we implemented a systematic metabolic engineering strategy comprising: (1) increasing intracellular SAM supply, (2) overexpressing key genes, (3) knocking out the negative regulators …

Biofabrication of novel silver and zinc oxide nanoparticles from Fusarium solani IOR 825 and their potential application in agriculture as biocontrol agents of phytopathogens, and seed germination and seedling growth promoters.

Introduction: Plant pathogenic microorganisms adversely affect the growth and yield of crops, which consequently leads to losses in food pro … ity against Pectobacterium carotovorum. Moreover, AgNPs and ZnONPs inhibited the mycelial growth of Alternaria alternata, Fusarium culmorum, Fusarium oxysporum, Phoma lingam, and Sclerotinia sclerotiorum. MIC and MFC values of AgNPs ranged from 16-128 and 16-2048 μg mL -1, respectively. ZnONPs showed antifungal activity with MIC and MFC values of 128-2048 μg …

Evaluation of antifungal susceptibility and clinical characteristics in fungal keratitis in a tertiary care center in North India.

PURPOSE: To study the antifungal susceptibility of common corneal pathogenic fungi to antifungal agents in the North Indian population. MET … (n = 1) was natamycin: 8 μg/mL, amphotericin B: 0.75 μg/mL, posaconazole: 1.5 μg/mL. MIC against of Alternaria (n = 1) was voriconazole: 0.19 μg/mL, posaconazole: 0.094 μg/mL. MIC against Penicillium (n=1) was natamycin: 8 μg/mL, voriconazole: 0.25 μg/mL, itraconazole: 0.5 μg/mL, and Posaconazole: 0.125 μg/mL. CONCLUSION: Our observations highlight the vari …

Gamma rays-assisted bacterial synthesis of bimetallic silver-selenium nanoparticles: powerful antimicrobial, antibiofilm, antioxidant, and photocatalytic activities.

BACKGROUND: Bimetallic nanoparticles (BNPs) has drawn a lot of attention especially during the last couple of decades. A bimetallic nanopart … andard microbial strains including, Aspergillus brasiliensis ATCC16404, Candida albicans ATCC10231, Alternaria alternate EUM108, Fusarium oxysporum EUM37, Escherichia coli ATCC11229, Bacillus cereus ATCC15442, Klebsiella pneumoniae ATCC13883, Bacillus subtilis ATCC15442, and Pseudomonas aeruginosa ATCC6538 as a model tested pathogenic microbes. The individua …

Clinical Manifestations of Human Exposure to Fungi.

Biological particles, along with inorganic gaseous and particulate pollutants, constitute an ever-present component of the atmosphere and surfaces. Among these particles are fungal species colonizing almost all ecosystems, including the human body. Although inoffensive to most people, fungi can be responsible for several health problems, such as allergic fungal diseases and fungal infections. Worldwide fungal disease incidence is increasing, with new emerging fungal diseases appearing yearly. Reasons for this increase are the expansion of life expectancy, the number of immunocompromised patien

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… Disease | Etiological Agents | Risk Factors Farmer’s lung | Alternaria spp. A. fumigatus A. glaucus Botrytis spp. … Subcutaneous alternariosis in a renal transplant recipient with pulmonary Alternaria infection; ( L ): Alternaria spp. in tissue showing pigmented conidia (Gomori methenamine silver stain). …

[A clinical analysis of 1 414 cases of fungal keratitis].

Objective: To discuss clinical features and treatments of fungal keratitis, and to provide statistical data for clinical therapy and increas … surgery from 973 patients (68.8%). Most of the fungi were Fusarium (595 cases, 61.1%), followed by Alternaria (184 cases, 18.9%) and Aspergillus (119 cases, 12.2%). There were 603 cases (42.7%) of superficial and middle stromal infiltration, 614 cases (43.4%) of deep stromal infiltration and 197 cases (13.9%) of full-thickness corneal infiltration. Diameter …

Resolution of sick building syndrome in a high-security facility.

The main objective of this article is to serve as a case study for other industrial hygiene (IH) professionals' review as a "real world" eff … utes each at 28.3 liters/minute airflow. Cultures exhibited fungi such as Aspergillus, Penicillium, Alternaria, and Cladosporium. Certain strains of these fungi produce mycotoxins that may cause a variety of deleterious health effects such as those described by occupants. Initial 1994 airborne fungal concentrations ranged from 85 to 6157 colony forming units …

Проблемы с диагностикой и оказанием неотложной медицинской помощи в случае быстро прогрессирующего заболевания лёгких, вторичного и многократного заболевания миеломой.

Одновременное представление множественной миеломы (ММ) и межститиальной болезни легких (МЛ) остается исключительно редким, при этом ограниченная литература описывает оптимальные стратегии управления для этой двойной патологии. Мы сообщаем о сложном случае 62-year-old Мужчина с недавно поставленным диагнозом MM с цитогенетикой промежуточного риска (del13q, набирающий 1q), который одновременно представил быстро прогрессирующий ILD, демонстрирующий обычную интерститальную пневмонию (МСАГВ). Пациентка 6-month Клинический курс был отмечен участием многих организаций, периодическими инфекциями, тром

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… The hypersensitivity pneumonitis panel demonstrated markedly elevated Alternaria alternata-specific IgG (99 mgA/L; normal <30.0 mgA/L), along with raised Aspergillus fumigatus -specific IgG (35.50 mgA/L; normal <27.0 mgA/L) and pigeon serum protein, feather, and droppings-specific IgG (39.10 mgA/L; normal … Plasma cell-derived cytokine production: Malignant plasma cells in MM produce multiple cytokines (IL-6, TNF-α, IL-1β) that may trigger pulmonary fibrosis through Th2-mediated immune responses. 2) Infectious trigger: The elevated specific IgG antibodies to multiple fungal antigens (Aspergillus fumigatus, Alternaria …

Penile allotransplantation for penis amputation following ritual circumcision: a case report with 24 months of follow-up.

INTRODUCTION: Ritual circumcision complicated by gangrene is a leading cause of penile loss in young men in South Africa. This deeply rooted … per day. At 8 months after surgery, the patient had a skin infection with phaeohyphomycosis due to Alternaria alternata, which we treated with topical antifungal medication. Quality-of-life scores improved substantially after the operation (SF-36v2 mental health scores improved from 25 preoperatively, to 57 at 6 months and 46 at 24 months post transplant; p …

[Analysis of allergen sensitization profiles in patients with skin diseases at a hospital in Shanghai City from 2023 to 2024].

To investigate the differences in allergen-specific immunoglobulin E (specific immunoglobulin E, sIgE) profiles and levels between patients … with allergic skin diseases than in those with non-allergic skin diseases; however, sIgE levels for Alternaria alternata (Z=4.10, P<0.001), milk (Z=3.36, P=0.01), and egg white (Z=1.42, P=0.04) were significantly higher in patients with non-allergic skin diseases. Sex-stratified analysis revealed that female patients with non-allergic skin diseases had a sig …

Outbreak of Leucostoma Canker Caused by Leucostoma cincta on McIntosh Apple Trees in Wisconsin.

In fall 1996, cankers were observed on branches of 7- to 9-year-old apple trees (Malus domestica cvs. Empire and McIntosh, strains Marshall … ater turned brown. Conidium morphology was consistent with descriptions of Leucocytospora spp. (2). Alternaria spp. also were isolated frequently; other fungi, which were not identified, were isolated rarely. The presence of abundant pycnidia of Leuco-cytospora, but not perithecia of Leucostoma, on cankers was different from the signs described for Leucostom …

Microbial Keratitis in Thyroid Eye Disease: Clinical Features, Microbiological Profile, and Treatment Outcome.

PURPOSE: To report the incidence, clinical features, microbiologic profile, and risk indicators in the development of microbial keratitis in … , Corynebacterium sp., and Staphylococcus sp. Three eyes revealed a mixed infection of E. coli with Alternaria sp, and E. coli with Corynebacterioum amycolatum while 1 had Corynebacterium pseudodiptheriticum, and S. pneumoniae. Two eyes of the bilateral case showed no growth. Antibiotic susceptibility revealed 6 of the 7 gram-negative isolates were multidrug …

Clinical course of cow's milk protein allergy/intolerance and atopic diseases in childhood.

A cohort of 1,749 newborns from the municipality of Odense, born during 1995 at the Odense University Hospital, were followed up prospective … s (birch, grass, mugwort, dog, cat, horse, Dermatophagoidespteronyssinus, Dermatophagoides farinae, alternaria and cladosporium herbarum). Furthermore, lung function measurements were performed in children when 10 and 15 years of age. Based on controlled milk elimination and challenge procedures, the diagnosis of CMPA/I was confirmed in 39 out of 117 infants …