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Executive Dysfunction-A Serious Game for Assessment in Real-Life Contexts: Development and Cross-Sectional Usability Study.

BACKGROUND: Traditional neuropsychological assessments often lack ecological validity and have limited sensitivity for detecting executive dysfunction (ED) in daily life. Although grounded in standardized tasks, they do not represent the complexity of real-world contexts. Serious games (SGs) have emerged as a promising approach by simulating ecologically valid environments involving dynamic, emotional, and socially embedded interactions. OBJECTIVE: This study aimed to (1) describe the development of a clinically oriented SG for assessing executive functioning in ecologically valid scenarios,

Autogenous bone grafts in oral implantology-is it still a "gold standard"? A consecutive review of 279 patients with 456 clinical procedures.

BACKGROUND: This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. METHODS: A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the years of 2009 until 2011 with autologous bone transplantation prior to secondary implant insertion. Intraoral donor sites (crista zygomatico-alveolaris, ramus mandible, symphysis

What Orthopaedic Operating Room Surfaces Are Contaminated With Bioburden? A Study Using the ATP Bioluminescence Assay.

BACKGROUND: Contaminated operating room surfaces can increase the risk of orthopaedic infections, particularly after procedures in which hardware implantation and instrumentation are used. The question arises as to how surgeons can measure surface cleanliness to detect increased levels of bioburden. This study aims to highlight the utility of adenosine triphosphate (ATP) bioluminescence technology as a novel technique in detecting the degree of contamination within the sterile operating room environment. QUESTIONS/PURPOSES: What orthopaedic operating room surfaces are contaminated with biobur

Cost-effectiveness Analysis of Nutrition Facts Added-Sugar Labeling and Obesity-Associated Cancer Rates in the US.

ImportanceObesity-associated cancer burdens are increasing in the US. Nutrition policies, such as the Nutrition Facts added-sugar labeling, may reduce obesity-associated cancer rates.ObjectiveTo evaluate the cost-effectiveness of Nutrition Facts added-sugar labeling and obesity-associated cancer rates in the US.Design, setting, and participantsA probabilistic cohort state-transition model was used to conduct an economic evaluation of added-sugar labeling and 13 obesity-associated cancers among 235 million adults aged 20 years or older by age, sex, and race/ethnicity over a median follow-up of

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… Earlier studies reported that, after the US Congress passed a national law requiring chain restaurants with 20 or more outlets to list calories on menus in 2010, the mean calorie content per menu item fell from 327 kcal in 2008 to 318 kcal in 2015 in 44 of the 100 largest chain restaurants. 33 A meta-analysis … Sociodemographic disparities among fast-food restaurant customers who notice and use calorie menu labels . J Acad Nutr Diet . 2015 ; 115 ( 7 ): 1093 - 1101 . doi: 10.1016/j.jand.2014.12.004 25659920 37 Elbel B , Kersh R , Brescoll VL , Dixon LB . …

Longevity of dental amalgam in comparison to composite materials.

HEALTH POLITICAL BACKGROUND: Caries is one of the most prevalent diseases worldwide. For (direct) restaurations of carious lesions, tooth-coloured composite materials are increasingly used. The compulsory health insurance pays for composite fillings in front teeth; in posterior teeth, patients have to bear the extra cost. SCIENTIFIC BACKGROUND: Amalgam is an alloy of mercury and other metals and has been used in dentistry for more than one hundred and fifty years. Composites consist of a resin matrix and chemically bonded fillers. They have been used for about fifty years in front teeth. Amal

Surveillance for waterborne-disease outbreaks--United States, 1995-1996.

PROBLEM/CONDITION: Since 1971, CDC and the U.S. Environmental Protection Agency have maintained a collaborative surveillance system for collecting and periodically reporting data that relate to occurrences and causes of waterborne-disease outbreaks (WBDOs). REPORTING PERIOD COVERED: This summary includes data for January 1995 through December 1996 and previously unreported outbreaks in 1994. DESCRIPTION OF THE SYSTEM: The surveillance system includes data about outbreaks associated with drinking water and recreational water. State, territorial, and local public health departments are primari

Hip resurfacing arthroplasty reduces dislocation and infection rates without differences in clinical outcomes compared to short and standard stems: A Network Meta-Analysis.

BACKGROUND: Total hip arthroplasty (THA) and hip resurfacing arthroplasty (HRA) are established treatments for hip osteoarthritis. Recent advancements have introduced short-stem THA, which offers potential advantages in terms of bone preservation and biomechanical restauration. None of previous studies compared these three surgical interventions. The aim of this network meta-analysis (NMA) is to compare HRA, short stem and standard stem in THA in terms of: (1) complications rate (global, infection and dislocation rate), (2) clinical outcomes (WOMAC, Harris Hip Score (HHS), Oxford Hip Score (OH

Выдержка гемпта (Extractum Cannabis) в деле " Лечение кишечных расстройств и диспепсии: исторические сведения из Барселоны, Испания " .

В этом исследовании изучается траектория интереса и использования экстракта каннабиса (выдержка канабиса сативы L.) для симптоматического лечения легких желудочно-кишечных расстройств и диспепсии в Барселоне XIX и начала XX века (Каталония, Испания) 1939, на основе обзора первичных источников. Цель настоящего документа заключается в том, чтобы представить исторический фармацевтический и прикладный обзор использования гематома (Cannabis L.) в медицинских целях до его запрещения, способствуя тем самым его признанию в качестве медицинского продукта. Представленная информация свидетельствует об ис

[Surgery of abdominal aorta with horseshoe kidney].

Seventy one surgical procedures on abdominal aorta in patients with horseshoe kidney have been reported in literature until 1980. Bergan reviewed 30 operations of abdominal aortic aneurysms (AAA) in these patients until 1974. Of them 3 AAA were ruptured. Gutowitz noticed 57 surgically treated AAA in patients with horseshoe kidney until 1984. Over the period from 1991 to 1996 thirty nine new cases were reported , including 2 ruptured AAA. The surgery of the abdominal aorta in patients with horseshoe kidney is associated with the following major problems: -reservation of anomalous (aberrant) ren

Neuronal injury in chronic CNS inflammation.

INTRODUCTION: Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system which is characterized by inflammatory demyelination and neurodegeneration. Neurological symptoms include sensory disturbances, optic neuritis, limb weakness, ataxia, bladder dysfunction, cognitive deficits and fatigue. PATHOPHYSIOLOGY: The inflammation process with MS is promoted by several inflammatory cytokines produced by the immune cells themselves and local resident cells like activated microglia. Consecutive damaging pathways involve the transmigration of activated B lymp

Introducing the dataset for measuring centrality for sustainability-A case study of Pecinci municipality, Serbia.

The paper presents a novel way of integrating data for sustainable planning of central activities at the spatial planning level. The method … g on central activities such as industrial production, manufacturing, commercial offices, commerce, restaurants, cafes, cultural, government, and social services. Dataset presented in this article consists of analyzed data as follows: (1) Raw data on concentration in Municipality of Pećinci; (2) Formula for measuring centrality of general (community) and spec …

Foodborne Illness Outbreaks at Retail Food Establishments - National Environmental Assessment Reporting System, 25 State and Local Health Departments, 2017-2019.

PROBLEM/CONDITION: Each year, state and local public health departments report hundreds of foodborne illness outbreaks associated with retail food establishments (e.g., restaurants or caterers) to CDC. Typically, investigations involve epidemiology, laboratory, and environmental health components. Health departments voluntarily report epidemiologic and laboratory data from their foodborne illness outbreak investigations to CDC through the National Outbreak Reporting System (NORS); however, minimal environmental health data from outbreak investigations are reported to NORS. This report summariz…

National survey of patient perspectives on cost discussions among recipients of copay assistance.

BackgroundIndividuals with cancer and other medical conditions often experience financial concerns from high costs-of-care and may utilize copay assistance programs (CAP). We sought to describe CAP recipients' experiences/preferences for cost discussions with clinicians.MethodsWe conducted a national, cross-sectional electronic-survey from 10/2022 to 11/2022 of CAP recipients with cancer or autoimmune conditions to assess patient perspectives on cost discussions. We used multivariable logistic regression models to explore associations of patient perspectives on cost discussions with patient ch

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… We also asked participants whether healthcare costs led them to spend less money on lifestyle expenditures, including education, groceries, housing, clothing, dining at restaurants, or vacation. Figure 1. Patient-reported outcomes explored. … Individuals who reported spending less money on groceries (40% vs 33%, P = .004), clothing (48% vs 40%, P = .004), dining at restaurants (62% vs 52%, P < .001), and vacation (63% vs 54%, P < .001) were more likely to want their doctors to discuss costs with them. …

Расширение повседневной памяти и участие в многочисленных склерозах: экспериментальное исследование метакогнитивной стратегии вмешательства.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Когнитивная дисфункция у лиц с множественным склерозом (МС) связана с ограничениями в повседневной деятельности и ограниченным участием. Существующие меры по устранению когнитивной дисфункции часто свидетельствуют о непоследовательном переходе на повседневную деятельность и, как правило, требуют частых посещений клиник, что может быть сопряжено с трудностями для пациентов с НР из-за проблем с мобильностью. Для преодоления этого барьера мы разработали систему когнитивного вмешательства на основе телемедицины, которая основана на подготовке по вопросам метакогнитивной стра

Association of activity-based food environment index with obesity-related cancer mortality in the US.

BackgroundObesity and obesity-related cancers contribute to rising healthcare costs and declining life expectancy in the US and improving diet quality plays a crucial role in reversing such trends. Existing studies on the relationship between healthy food access and obesity-related cancer mortality present mixed findings, whereas food procurement activities are largely overlooked. The paper aims to construct a novel food environment index based on residents' food retailer visits, and then compare it with the location-based food environment index regarding the strength of associations with obes

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… Less healthy food retailers include limited-service restaurants (NAICS 722513) and convenience stores (NAICS 445120). We also complemented other limited-service restaurants by including food carry-out (SIC code 5812–06) and pizza restaurants (SIC code 5812–22). … Higher densities of fast-food and full-service restaurants are not associated with obesity prevalence. Am J Clin Nutr. 2017;106:603–13. 24. Paulitsch RG, Dumith SC. Is food environment associated with body mass index, overweight and obesity? …

Experience of life quality from patients with aplastic anemia: a descriptive qualitative study.

BackgroundDespite the increasing incidence of aplastic anemia in China, few studies have explored its effect on the patients' quality of life from the perspective of these patients. In fact, patients with aplastic disorder live with the disease for a long time, and need to face a variety of difficult realities, including multiple disease symptoms and drug side effects, heavy burden of medical costs, difficulties in social reintegration, and negative emotional distress. Therefore, this study used descriptive qualitative research to explore the direct and rich quality-of-life experiences of pati

Taxation of the fat content of foods for reducing their consumption and preventing obesity or other adverse health outcomes.

BACKGROUND: Overweight and obesity are increasing worldwide and are considered to be a major public health issue of the 21st century. Introd … other relevant sources of fat intake (e.g. packaged or processed food) or other food outlets (e.g. restaurants or cafeterias); hence, we judged the evidence on the effect of taxation on total fat consumption or saturated fat consumption to be very uncertain. We did not identify evidence on the effect of the intervention on energy intake or the incidence or p …

What are safe hemoglobin, neutrophil and platelet counts for people with hematological malignancies to participate in exercise and activities of daily living: a scoping review.

PurposeThe aim of this scoping review was to summarize the extent of the literature in relation to safe levels of platelet, hemoglobin and neutrophil count for people with hematological cancers to participate in exercise or activities of daily living (ADLs).MethodsA comprehensive search for this scoping review was completed in July 2024 across five databases: the Cochrane Library, Embase, PEDro, PubMed and OTSeeker. Original studies, reviews and expert opinion papers were included if they focused on people with active hematological cancer diagnoses or those undergoing treatment affecting bone

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… Hemoglobin: transfusions given according to individual limits, on basis of symptoms and co-morbidities Neutrophil: if < 0.5, told to avoid persons carrying infection or who had a fever, could leave their homes for daily walking however not allowed to go to supermarkets, cinemas, restaurants, buses, where … Hemoglobin: transfusions given according to individual limits, on basis of symptoms and co-morbidities Neutrophil: if < 0.5, told to avoid persons carrying infection or who had a fever, could leave their homes for daily walking however not allowed to go to supermarkets, cinemas, restaurants, buses, where …

Сопоставление воздействия смартфонного и личного обучения на качество жизни и навыки преодоления проблем у пациентов с множественным склерозом: случайное контролируемое испытание.

Множество проблемных признаков и симптомов множественного склероза (MS) снижает качество жизни пациентов (QOL) и способность справляться с ними. Личное (F2F) обучение является эффективным и практичным, поскольку оно позволяет более активно участвовать и активно учиться. Использование мобильных медицинских технологий для улучшения состояния здоровья населения в настоящее время открывает широкие возможности для создания более эффективной системы здравоохранения. Цель этого исследования состояла в том, чтобы определить последствия программы самообслуживания с использованием two - образование на о

Medication for bone loss in female patients with anorexia nervosa: a systematic review and management algorithm.

PURPOSE: Anorexia Nervosa can have a major impact on bone health through low bone mass and bone loss. Considering the lack of consensual guidelines for the prevention and treatment of bone loss in this condition, a systematic review was performed to provide practical treatment guidance for clinicians. METHODS: We systematically searched Medline, Cochrane, Psychinfo, and the Web of Science for anorexia nervosa AND (osteopenia OR osteoporosis OR bone density OR bone loss) AND (prevention OR treatment OR medication OR therapeutic) in clinical studies from March 1st, 2017, to October 31st, 2024,