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Clinical course of illness in women with early onset puerperal psychosis: a 12-year follow-up study.

OBJECTIVE: To complete a follow-up analysis at a mean of 12 years after patients had presented with an early onset puerperal psychotic index episode. METHOD: A retrospective design was used. Patients with puerperal psychosis and onset within 4 weeks after childbirth who had been referred to the Psychiatric Department of the Ludwig Maximilian University of Munich, Munich, Germany, between 1975 and 1995 (maximum: 24 years, minimum: 7 years) were followed up after a mean of 12 years post index episode. Ninety patients were included in the study. Before the index episode, 35 of the patients had p

Believing processes during the COVID-19 pandemic in individuals with bipolar disorder: An exploratory study.

BACKGROUND: Believing or "credition" refers to psychological processes that integrate the cognitions and emotions that influence our behavior. In the credition model by Angel and Seitz, four parameters are postulated: proposition, certainty, emotion and mightiness. It is assumed that believing processes are influenced by both the individual as well as socio-cultural factors and external circumstances. External or environmental circumstances can include threatening situations such as the ongoing pandemic. It has been hypothesized that believing processes related to the pandemic differ between i

Effects of olanzapine on resting heart rate in Japanese patients with schizophrenia.

It has long been known that antipsychotic drugs (ATP) causes tachycardia, however details such as the differences between ATP are not well k … ectively. To analyze the RHR, electrocardiographic measurements were obtained. At the same day, the Brief Psychiatric Rating Scale (BPRS) was evaluated, and fasting blood samples were drawn after an overnight fast of at least 8 h to examine electrolytes. Both Study 1 and 2 were conducted with the approval of the Gene Ethics Committee of Niigata University Graduate School of Med …

Delusional Themes Across Affective and Non-Affective Psychoses.

The current debate about the diagnostic significance of delusion revolves around two positions. The neurocognitive position conceives delusi … criteria, and in 348 patients were established with the SCID-I. All patients were administered the Brief Psychiatric Rating Scale (BPRS). In each patient, the presence of somatic delusions and delusions of guilt, grandiosity, and persecution was determined by examining the scores on relevant BPRS items. Delusions of guilt were almost pathognomonic for a psychotic depressive co …

Ziprasidone in adolescents with schizophrenia: results from a placebo-controlled efficacy and long-term open-extension study.

OBJECTIVE: The purpose of this study was to evaluate the short- and long-term efficacy, safety, and tolerability of ziprasidone in adolescen … rasidone (40-160 mg/day, based on weight) or placebo. Primary end-point was change from baseline in Brief Psychiatric Rating Scale-Anchored (BPRS-A) total score. Safety assessments included adverse events, vital signs, laboratory measures, electrocardiograms, weight and body mass index, and movement disorder ratings. RESULTS: Planned interim analysis for the primary end-point …

Mental disorder in Polish families: is diagnosis a predictor of caregiver's burden?

OBJECTIVE: To test whether a caregiver's burden is associated with the patient's psychiatric diagnosis and to find other predictors of family burden; to provide Polish data on the issue to international literature. METHOD: Of 377 eligible subjects, 141 were interviewed on admission to the mental hospital using Brief Psychiatric Rating Scale, Manchester Short Assessment of Quality of Life, Groningen Social Disability Schedule and Client's Sociodemographic and Clinical History Inventory. Their caregivers completed the Involvement Evaluation Questionnaire (IEQ). Subjects were grouped according t…

Long-term Multidomain Patterns of Change After Traumatic Brain Injury: A TRACK-TBI LONG Study.

BACKGROUND AND OBJECTIVES: Traumatic brain injury (TBI) may be a chronic condition carrying risk of future sequelae; few prospective studies examine long-term postinjury outcomes. We examined the prevalence of functional, cognitive, and psychiatric change outcomes from 1 to 7 years postinjury. METHODS: Transforming Research and Clinical Knowledge in TBI LONG (TRACK-TBI LONG) participants were prospectively enrolled within 24 hours of injury and followed up to 1 year postinjury; a subset participated in long-term follow-up from 2 to 7 years postinjury. Reliable change thresholds for the Brief

Prediction of attachment status from observation of a clinical intensive psychotherapy interview.

OBJECTIVE: The present study addresses whether it is possible to accurately determine a subject's Adult Attachment Interview (AAI) classification by observing a video-recorded clinical psychotherapy discussion that uses the principles of Intensive Short-Term Dynamic Psychotherapy (ISTDP). METHOD: A random sample of eight of the author's (Robert J. Nebrosky) private practice patients participated in an AAI administered by an experienced interviewer. The authors were blind to the results of the AAI, which were scored and classified by Erik Hesse, PHD (consultant and expert in AAI coding and cla

Defense mechanisms after brief cognitive-behavior group therapy for panic disorder: one-year follow-up.

Changes in defense mechanisms have been shown in long-term psychodynamic treatment. The aim of this study was to examine the changes that occurred after brief cognitive-behavior group therapy in the defense style of panic disorder patients that had failed to respond to pharmacotherapy. Forty-seven patients participated in the study and severity of panic disorder was evaluated by Clinical Global Impression. Defense mechanisms were evaluated by the Defense Style Questionnaire. Patients decreased the use of maladaptive defenses after cognitive-behavior group therapy, and the change in immature de

Changes over time in frontotemporal activation during a working memory task in patients with schizophrenia.

Studies on working memory (WM) dysfunction in schizophrenia have reported several functionally aberrant brain areas including prefrontal and temporal cortex. Longitudinal studies have shown changes in prefrontal activation during treatment. We used event-related functional magnetic resonance imaging and a parametric verbal WM task to investigate cerebral function during WM performance in healthy subjects and medicated patients with schizophrenia with an acute symptom exacerbation. Patients were scanned twice: within the first week after admission to the hospital and after 7-8 weeks of a multim

Brief psychotherapy of bereavement reactions. The relationship of process to outcome.

We studied the relationship of dispositional and process variables with outcome in 52 bereaved patients given time-limited dynamic psychotherapy. Outcomes were generally favorable in symptom relief and improvement in relationship and occupational functioning. Patients' symptoms improved more than did their social and work functioning. Pretreatment levels of impairment or distress were significantly related to outcome, but most demographic and dispositional variables did not predict outcome. Process variables examined in relation to outcome--therapeutic alliance and actions by the therapist--we

CSF norepinephrine in schizophrenia is elevated prior to relapse after haloperidol withdrawal.

Thirty-two male DSM-III diagnosed schizophrenic patients received a lumbar puncture (LP) during chronic haloperidol treatment that was followed by replacement with placebo for up to 6 weeks. Fourteen patients relapsed on placebo within 6 weeks. Patients received a second LP at the time of relapse or at the end of 6 weeks if they had not relapsed. Bunney-Hamburg Global Psychosis Ratings of the day and the hours of sleep of the night before the LP were obtained, as were the Brief Psychiatric Ratings Scale (BPRS) ratings during the week of the LPs. CSF norepinephrine (NE), 3-methoxy-4-hydroxyphen

The correlations of insomnia symptoms with psychopathology and hematological parameters as well as gender differences in patients with schizophrenia.

Patients with schizophrenia are at high risk for insomnia, but the associated influencing factors in this population have not been fully elucidated. Therefore, this study aimed to investigate the associations between insomnia symptoms and psychopathological indicators and hematological parameters in patients with schizophrenia, as well as to analysis the gender differences. From October 2022 to December 2024, this study recruited 184 patients with schizophrenia. The Insomnia Severity Index Scale (ISI), Brief Psychiatric Rating Scale (BPRS), Calgary Depression Scale (CDSS), and Modified Overt A…

Change in Emotional Arousal Variance in Clients with Borderline Personality Disorder during a Brief Psychiatric Treatment.

UNLABELLED: <p>Background: Research in the field of psychotherapy suggests that emotional arousal (EA) might be a key element to therapeutic success. However, its relevance depends on a situation-bound complex process, requiring its assessment at the right time and in relation to significant personal themes. METHODS: This article is a secondary analysis of a 4-month treatment RCT with two arms (General Psychiatric Management and Treatment As Usual) for borderline personality disorder (BPD). Fifty-five clients with BPD (GPM group: n = 28; TAU group: n = 27) as well as healthy controls (n = 29)

Correlation Between Serum Amisulpride Concentration, Therapeutic Efficacy, and Glycolipid Metabolism in the Treatment of Adult Female Schizophrenia.

BACKGROUND: Amisulpride is a novel atypical antipsychotic (AAP) with slower absorption, metabolism, and excretion in females, potentially le … post-treatment with amisulpride. Key parameters measured included serum amisulpride concentration, Brief Psychiatric Rating Scale (BPRS) scores, fasting blood glucose, total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and side effect scores. RESULTS: Serum amisulpride levels significantly increased at 2, 4, and 8 weeks …

Schizophrenia risk loci from xMHC region were associated with antipsychotic response in chronic schizophrenic patients with persistent positive symptom.

We examined whether common variants from the extended major histocompatibility complex (xMHC) region contribute to the response to antipsychotic drugs (APDs) in patients with schizophrenia with persistent psychosis. Subjects participated in a prospective longitudinal study of the effect of APDs on psychopathology were temporally split into discovery (n = 88) and replication (n = 42) cohorts. The primary endpoint was a change in Brief Psychiatric Rating Scale at 6-week or 6-month after treatment. rs204991 (β = 3.917, p = 3.72 × 10-6), the strongest signal associated with response at 6-week was …

Distinct aetiopathogenesis in subgroups of functional dyspepsia according to the Rome III criteria.

BACKGROUND AND OBJECTIVE: Whether there is distinct pathogenesis in subgroups of functional dyspepsia (FD), the postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) remains controversial. We aimed to identify the risk factors of FD and its subgroups in the Chinese population. METHODS: Patients with dyspepsia and healthy subjects who underwent gastric cancer screening were enrolled in this multicentre study from 2010 to 2012. All patients were evaluated by questionnaire, oesophagoduodenoscopy, histological examination and Helicobacter pylori tests. Subgroups of FD were class

Association of enhanced limbic response to threat with decreased cortical facial recognition memory response in schizophrenia.

OBJECTIVE: Recognition memory of faces is impaired in patients with schizophrenia, as is the neural processing of threat-related signals, bu … eatening versus nonthreatening affect were evaluated, and correlations with symptom severity (total Brief Psychiatric Rating Scale score) were examined. Functional connectivity analyses examined the relationship between activation in the amygdala and cortical regions involved in recognition memory. RESULTS: Patients performed the task more slowly than healthy comparison subjec …

Transcranial magnetic stimulation for treatment resistant depression: six case reports and review.

BACKGROUND: Depressive disorder is a common, recurrent, and chronic disorder that is a leading cause of functional impairment and disability An estimated 20-40% of patients do not benefit sufficiently from existing therapies. Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment for psychiatric illness. Evidences support its use in depression, either alone or combined with antidepressants. During rTMS, a time-varying current is discharged in an insulated coil attached to the scalp surface, generated a brief dynamic magnetic field that can freely, non-invasively penetrate

Сексуальная дисфункция и самоубийство у пациентов с биполярным расстройством и однополярной депрессией.

ВВЕДЕНИЕ: У пациентов с психическими расстройствами, особенно у больных с расстройствами настроения, часто случаются нарушения половой функции, которые недооцениваются. Немногие исследования были посвящены изучению взаимосвязи между сексуальными дисфункциями и клиническими характеристиками расстройств настроения. AIM: Цель настоящего исследования заключалась в изучении частотности сексуальной дисфункции у пациентов с биполярным расстройством I (BD) и однополярной депрессией (UD) в плане контроля над субъектами, а также их связи с самоубийством.Основные меры: Оценки включали: структурированное

Совпадение в аннотации оригинала
INTRODUCTION: Impairment in sexual function is frequent and underestimated in patients with mental disorders, particularly in those with moo … ew for Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (SCID-I/P), the 24-item Brief Psychiatric Rating Scale and the Mood Spectrum Self-Report, a questionnaire exploring lifetime mood spectrum symptomatology including symptoms of sexual functioning and suicidality. METHODS: A consecutive sample of 142 patients (60 BD and 82 UD) and a comparison group of 1 …