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Correction: Artificial testis: a testicular tissue extracellular matrix as a potential bio-ink for 3D printing.

Correction for 'Artificial testis: a testicular tissue extracellular matrix as a potential bio-ink for 3D printing' by Zahra Bashiri et al., Biomater. Sci., 2021, 9, 3465-3484, https://doi.org/10.1039/D0BM02209H.

Development of a Stereolithography 3D Printing-Based Micropatterning Method to Study Endothelial-to-Mesenchymal Transition Mechanobiology.

Endothelial-to-mesenchymal transition (EndMT) is the process of endothelial cells undergoing molecular changes that shift their phenotype fr … we aimed to develop an accessible micropatterning platform and created a stereolithography (SLA) 3D printing-based polydimethylsiloxane (PDMS) protein-stamp fabrication platform to create customized patterns of ECM proteins to study endothelial cell chirality during EndMT. Human aortic endothelial cells (HAECs) were treated with the inflammatory cytokine t …

Percutaneous Closure of Left Ventricular Outflow Tract to Left Atrium Fistula With 3-Dimensional Printing Simulation.

CASE SUMMARY: We present a case of a 31-year-old man with a history of aortic valve endocarditis and surgical aortic intervention. Computed tomography revealed a complex serpiginous fistula with 2 openings between the left ventricular outflow tract and the left atrium. Using 3-dimensional printing simulation for device fit testing and planning, the "mother-in-daughter" system, multimodality guidance with computed tomography angiography C-arm prediction, and 3-dimensional transesophageal echocardiogram guidance successfully guided an 18-mm Cribriform Amplatzer device deployed via a retrograde a…

Four-Dimensional Printing of Shape Memory Polymers for Biomedical Applications: Advances in DLP and SLA Manufacturing.

Shape memory polymers (SMPs) represent an innovative class of materials that possess programmed, reversible shape-changing capabilities in response to external stimuli. The recent emergence of SMPs' advanced manufacturing, specifically 4D printing, has created exceptional opportunities for use in biomedical engineering. This review presents a critical synthesis of the latest advances in the chemistry, biomedical applications, manufacturing strategies, and clinical translation of SMPs, highlighting vat photopolymerization techniques, such as stereolithography (SLA) and digital light processing …

Deformation Characterization of Glass Fiber and Carbon Fiber-Reinforced 3D Printing Filaments Using Digital Image Correlation.

The paper offers an in-depth deformation study of glass fiber-reinforced and carbon composite filaments of 3D printers. During the certification, the authors used DIC (Digital Image Correlation) as a full-field strain measurement technique to explore key material traits as a non-contact optical measurement method. The insights captured through the DIC technology enabled to better understand the localized strain distributions during the loading of these reinforced filaments. The paper analyzes the glass fiber and carbon fiber filaments used in 3D printing that are reinforced with these material…

Miniaturized High-Throughput Amorphous Solid Dispersion Screening via Picoliter Volume 2D-Inkjet Printing of Formulation Microarrays.

Many new drug substances exhibit poor physicochemical properties and therefore require significant time and material resources to develop in … tively late in the lead optimization process. Herein, we report the application of picoliter inkjet printing of drugs and polymers from solution to create addressable formulation microarrays. This allows the efficient screening of drug-polymer compositions while only requiring micrograms or less of the drug substance. A total of eight model compounds, name …

Compression mechanical properties of porous polylactic acid scaffolds generated by 3D printing and sterilized with autoclave.

INTRODUCTION AND OBJECTIVES: Three-dimensional (3D) printing and polylactic acid (PLA) have attacted considerable interest in the medical field thanks to their versatility. 3D printers can reproduce the microarchitecture of the designed objects and PLA has mechanical properties similar to bone. This makes the technology highly promising for personalized treatment of bone defects. In this article explores the changes to the designed object suffers after the printing, sterilization, and its behavior when subjected to compression forces before and after autoclave sterilization. METHODS: PLA scaf…

HME coupled with FDM 3D printing of a customized oral solid form to treat pediatric epilepsy.

Interest in hot-melt extrusion (HME) and fused deposition material (FDM) printing has increased in recent years, for the production of tailored medications for patients with specific requirements, such as pediatrics. Liquid forms are often preferred for children but these forms are less stable than oral solid forms (such as tablets or powder), requiring preservative not always suitable for children. Then, the aim of this study is to develop a dose-adapted dispersible 3D printed forms using HME with FDM to treat pediatric epilepsy. Polyethylene oxide (PEO)-based 3D printed forms were developed …

Borax - and tannic acid-based post-3D-printing treatment to tune the mechanical properties of scaffolds.

Digital light processing (DLP) methods are constrained by the narrow range of cell-compatible resins, limiting their use in biomedical applications that require varied mechanical and biofunctional properties. Current bioresins based on natural polymers such as methacrylated gelatine or alginate usually lack sufficient stretchability and toughness. In this study, we propose a post-processing strategy to tune the mechanical and functional properties of a DLP printable polyethylene glycol diacrylate (PEGDA)/polyvinyl alcohol (PVA) resin via simple treatment with 5% (w/v) tannic acid (TA) or borax

Inkjet printing of pharmaceutical tattoos for the direct deposition of oestradiol onto skin in turner syndrome.

Turner syndrome, a rare chromosomal disorder affecting 1 in 2500 females, is characterized by the partial or complete absence of the second … roducibility. Dose linearity was confirmed (R2 > 0.96) with 3.8 ± 0.5 µg of E2 delivered per single printing pass using a 2 mg/mL pharma-ink. Personalised dosing is achievable by altering the concentration of E2 in the ink or by adjusting the number of printing passes, ideal for young Turner syndrome patients who require periodic dose adjustments. In vitro …

Advancements in 3D modeling technologies for congenital heart disease: integrating 3D printing, virtual reality, and holograms.

This review examines the application of advanced imaging technologies in pediatric cardiology, focusing on enhancing the visualization of ca … a range of imaging tools, from low-cost virtual reality, mixed reality, and three-dimensional (3D) printing to more advanced technologies, and explores their clinical applications in CHD. Through a literature analysis, the paper offers practical insights to help integrate and optimize these technologies, aiming to improve diagnostic accuracy and patient c …

Hybrid methacrylated PCL/inulin photosensitive resins for 3D printing: a step forward in bone tissue engineering.

This study addresses the need for innovative, biocompatible photopolymerizable resins for resin-based 3D printing (3DP) in bone tissue engineering (BTE). A new class of hybrid resins was developed by combining polycaprolactone trimethacrylate (PCLTMA) of two molecular weights with methacrylated inulin (INUMA) at varying concentrations. This strategy aimed to overcome the hydrophobicity and slow degradation of PCL by introducing a more hydrophilic and bioactive component, while maintaining high printability. The resins were characterized and processed into macroporous scaffolds via stereolithog…

Presentation of complex laryngotracheal surgeries using CT-based 3D models and 3D printing: a technical note.

INTRODUCTION: Slide laryngotracheopexy for cricotracheal stenosis and extended partial laryngectomy combined with tracheopexy for T2-T3 glottic tumors represent novel, complex laryngotracheal surgeries requiring meticulous preoperative planning. METHODS: In addition to conventional diagnostic tools (imaging, endoscopy), digital/virtual 3D techniques along with 3D printing - also referred to as Additive Manufactoring (AM)- allow for the creation and application of CT-based virtual and 3D-printed models of the larynx and the trachea. These 3D technologies can facilitate surgical team preparatio…

Using material extrusion 3D printing for static computer-assisted implant surgery: An in vitro accuracy study.

OBJECTIVE: This study evaluated the accuracy of static computer-assisted implant surgery (sCAIS) using commercial implant planning software (Blue Sky Plan 4) combined with material extrusion (ME) and digital light processing (DLP) 3D printing technologies. METHODS: A mandibular typodont model with three missing teeth was used in the virtual implant planning software. Surgical guides were designed in a splint-type configuration and fabricated using ME and DLP. A total of 40 implants were placed following a fully-guided protocol. Accuracy was assessed by measuring coronal, apical, and angular d…

[Clinical and histological evaluation of three-dimensional printing individualized titanium mesh for alveolar bone defect repair].

OBJECTIVES: To evaluate the osteogenic efficacy of three-dimensional printing individualized titanium mesh (3D-PITM) as a scaffold material in guided bone regeneration (GBR). METHODS: 1) Patients undergoing GBR for alveolar bone defects were enrolled as study subjects, and postoperative healing complications were recorded. 2) Postoperative cone beam computed tomography (CBCT) scans acquired at least 6 months post-surgery were used to calculate the percentage of actual bone formation volume. 3) Alveolar bone specimens were collected during the first-stage implant surgery for histomorphometric …

Применение MR Pinger для печати позволило получить значения T1 и T2 в мозге взрослых: системный обзор.

ВВЕДЕНИЕ: Магнитная резонансная съемка (MRI) имеет важное значение для изображений мозга, однако традиционные методы основаны на качественном контрасте, являются трудоемкими и подвержены колебаниям. Магнитный резонансный отпечаток пальцев (MRF) устраняет эти ограничения, позволяя быстро и одновременно картировать свойства многочисленных тканей, таких как T1, T2. Используя динамические параметры приобретения и предварительно составленный словарь сигналов, МРФ обеспечивает надежные качественные карты, повышая диагностическую точность и расширяя применение клинических и исследовательских технолог

Совпадение в аннотации оригинала
INTRODUCTION: Magnetic resonance imaging (MRI) is essential for brain imaging, but conventional methods rely on qualitative contrast, are time-intensive, and prone to variability. Magnetic resonance finger printing (MRF) addresses these limitations by enabling fast, simultaneous mapping of multiple tissue properties like T1, T2. Using dynamic acquisition par…

Impact of introducing 3D printing-assisted surgery into clinical practice for traumatic pelvic and acetabular fractures.

BACKGROUND: Given the novelty of three-dimensional (3D) printing-assisted fracture surgery in orthopaedics, surgeon familiarity is limited and learning curve is high. As such, it is unclear how the introduction of 3D printing into clinical practice for pelvic and acetabular fracture surgery would impact perioperative outcomes. The aim of this study was to determine the impact of introducing 3D printing-assisted surgery on perioperative outcomes for traumatic pelvic and acetabular fractures. METHODS: We retrospectively identified consecutive patients who underwent surgical fixation of traumati…

Intaglio surface trueness of dentures bases fabricated with 3D printing vs. conventional workflow: a clinical study.

The latest generation of intraoral scanners can record the prosthetic field with relative ease, high accuracy and comfort for the patient, and have enabled fully digital protocols for designing and manufacturing complete dentures. The present study aims to examine the intaglio surface trueness of 3D printed maxillary dentures produced by fully digital workflow in comparison with dentures produced by analogue clinical and laboratory prosthetic workflow. The edentulous maxillary arch of 15 patients was scanned with an intraoral scanner as well as the intaglio of the delivered conventional dentur

Drop-on-demand printing of amine-responsive fluorescence-ratiometric sensor array for online monitoring meat freshness.

Aiming to enable online freshness-monitoring of meat within modified-atmosphere package, we developed a ratiometric array that was fluorescently responsive to volatile organic compounds-ammonia (NH3) released by protein decaying. The array was consisted of two 3 mm × 6 mm rectangles precisely and uniformly printed with fluorescein isothiocyanate (FITC) as indicator and rhodamine B (RhB) as internal reference on the filter-paper, respectively. The fluorescence intensity of the array area was calibrated according to Green/Red ratio of the digitalized pixels extracted from images facilitated by a

Flexible Sensors with Enhanced Sensitivity and Broadened Detection Range Through Conformal Printing and Space-Confined Design.

Enhancing the sensitivity and extending the linear sensing range of flexible pressure sensors are crucial for their development and incorporation in wearable electronics. Conventional sensors face a trade-off between sensitivity and linear sensing range, which is often limited by the monotonicity of materials and structural design. To address this challenge, a new piezoresistive flexible sensor is developed in this work, drawing inspiration from the intricate microstructure and pressure-sensing capabilities of human skin. This advanced sensor is constructed with a dual-layer resistive sensing