Результаты поиска

Responsiveness to Change and Establishment of the Minimal Clinically Important Difference for the Cutaneous Sarcoidosis Activity and Morphology Instrument.

This case series study measures the responsiveness of the Cutaneous Sarcoidosis Activity and Morphology Instrument to changes in disease activity over time.

Is the minimal clinically important difference (MCID) in acute pain a good measure of analgesic efficacy in regional anesthesia?

In the field of acute pain medicine research, we believe there is an unmet need to incorporate patient related outcome measures that move beyond reporting pain scores and opioid consumption. The term "minimal clinically important difference" (MCID) defines the clinical benefit of an intervention as perceived by the patient, as opposed to a mathematically determined statistically significant difference that may not necessarily be clinically significant. The present article reviews the concept of MCID in acute postoperative pain research, addresses potential pitfalls in MCID determination and qu…

Articular Cartilage Repair of the Pediatric and Adolescent Knee with Regard to Minimal Clinically Important Difference: A Systematic Review.

OBJECTIVE: To perform a systematic review of clinical outcomes following microfracture (MFX), autologous chondrocyte implantation (ACI), osteochondral allograft transplantation (OCA), and osteochondral autograft transplantation system (OATS) to treat articular cartilage lesions in pediatric and adolescent patients. We sought to compare postoperative improvements for each cartilage repair method to minimal clinically important difference (MCID) thresholds. DESIGN: MEDLINE, Web of Science, Scopus, and Cochrane Library databases were searched for studies reporting MCID-validated outcome scores i…

Measuring acute postoperative pain using the visual analog scale: the minimal clinically important difference and patient acceptable symptom state.

BACKGROUND: The 100 mm visual analog scale (VAS) score is widely used to measure pain intensity after surgery. Despite this widespread use, it is unclear what constitutes the minimal clinically important difference (MCID); that is, what minimal change in score would indicate a meaningful change in a patient's pain status. METHODS: We enrolled a sequential, unselected cohort of patients recovering from surgery and used a VAS to quantify pain intensity. We compared changes in the VAS with a global rating-of-change questionnaire using an anchor-based method and three distribution-based methods (…

Minimal Clinically Important Difference of the Modified Barium Swallow Impairment Profile (MBSImP) Pharyngeal Total Score in Post-Stroke Dysphagia.

The Modified Barium Swallow Impairment Profile (MBSImP) is widely used to quantify swallowing physiology during videofluoroscopic swallowing assessment, but the minimal clinically important difference (MCID) for its pharyngeal total score in post-stroke dysphagia remains unclear. This study estimated the MCID for improvement in the MBSImP pharyngeal total score during inpatient rehabilitation. This prospective multicenter observational study included stroke survivors with dysphagia admitted for inpatient rehabilitation 2 weeks to 3 months after stroke onset. Baseline and 10-day follow-up asses…

Dyspnoea-referenced minimal clinically important difference in the resting inspiratory capacity response to short-acting bronchodilators in COPD patients.

BACKGROUND: In COPD, the clinical significance of bronchodilator-induced changes in inspiratory capacity (IC) at rest remains uncertain. Unlike forced expiratory volume in one second (FEV1), IC may better reflect symptom improvement, but no minimal clinically important difference (MCID) has been formally established. RESEARCH QUESTION: To relate short-acting bronchodilator (SABD)-induced dyspnoea relief in stable COPD patients at rest with the concomitant IC changes and determine the MCID of the latter. STUDY DESIGN AND METHODS: In 106 stable COPD outpatients undergoing routine lung function…

Radiographic predictors of functional and pain outcomes in Scheuermann's kyphosis: an ROC-based minimal clinically important difference (MCID) analysis.

STUDY DESIGN: Retrospective study. OBJECTIVES: This study uses receiver operating characteristic (ROC)-based minimal clinically important difference (MCID) analysis to quantify which radiographic changes best predict meaningful functional and pain improvements following posterior spinal fusion for Scheuermann's kyphosis (SK). SK is a rigid spinal deformity resulting in significant back pain and functional impairment, commonly affecting adolescents and young adults. Surgical correction aims to restore sagittal balance, but the relationship between radiographic correction and patient-reported o…

Psychometric Validation and Determination of the Minimal Clinically Important Difference for the Bronchiectasis Health Questionnaire in Adults with Bronchiectasis.

Rationale: The Bronchiectasis Health Questionnaire (BHQ) is a concise, self-administered, and disease-specific instrument for measuring health-related quality of life in bronchiectasis. Objectives: We sought to investigate the psychometric properties of a simplified Mandarin BHQ and determine the minimum clinically important difference (MCID) as a reliable clinical endpoint for assessing the efficacy of bronchiectasis treatments. Methods: A longitudinal, randomized controlled trial cohort of 357 patients treated with tobramycin inhalation solution or saline inhalation for Pseudomonas aeruginos

Минимальная клиническая разница EQ-5D-5L, SF-6Dv2, и QLU-C10D в гематологовых халатных пациентах Китая.

СПРАВОЧНАЯ ИНФОРМАЦИЯ: Оценка минимальной клинически важной разницы (MCID) в Евроколе five- Размер five- уровеньEQ-5D-5L) Короткая форма Six- Многомерная версия 2 (В тыс.SF-6Dv2), и качество жизни 10 РазмерыQLU-C10D) у китайских пациентов с гематологическими микроорганизмами. МЕТОДЫ: Продольные данные были получены от лимфомы и нескольких пациентов с миеломой, проходящих лечение в третичной больнице в Шанхае, Китай. Базовые обследования были проведены в 2022, с последующими мерами 2023 на 3- до 6-month интервалы. Всего 200 лимфома и 139 Множество пациентов миэломы были зачислены 78 и 89 Пациен

Совпадение в полном тексте источника
… Responsiveness and minimal clinically important difference of the EQ-5D-5L in cervical intraepithelial neoplasia: a longitudinal study. Health Qual Life Outcomes. 2020;18(1):324. 34. Sagberg LM, Jakola AS, Solheim O. … Responsiveness and the minimal clinically important difference for HM-PRO in patients with hematological malignancies. Blood. 2018;132(Supplement 1):2294. 37. Breeze J, Mehta J, Tremblay G, Shacham S, Shah J, Li L et al. …

Minimal clinically important difference in the World Health Organization Quality of Life Brief (WHOQOL-BREF) for adults with neurofibromatosis.

PURPOSE: This study aimed to estimate minimal clinically important difference (MCID) values for the World Health Organization Quality of Life Brief version (WHOQOL-BREF) among adults with neurofibromatosis (NF). An MCID is needed to demonstrate clinical meaningfulness of interventions for NF. METHODS: We estimated MCID for the WHOQOL-BREF: the quality of life (QoL) measure recommended by the Response Evaluation in Neurofibromatosis and Schwannomatosis International Collaboration. We used data from 228 clinical trial participants with NF type 1, NF type 2-related schwannomatosis, or schwannoma…

Minimal clinically important difference for change in 6-minute walk test distance of adults with pathology: a systematic review.

RATIONALE, AIMS, AND OBJECTIVES: The 6-minute walk test (6MWT) is widely used as a test of functional exercise capacity. Several studies have reported the minimal clinically important difference (MCID) for the 6MWT; however, the findings of the studies have not been examined in the context of one another. In this review, we aimed to summarize available information on the MCID for the 6MWT performed by patients with pathology. METHODS: Relevant literature was identified by searches of 3 electronic databases (PubMed, Scopus, and Cumulative Index of Nursing and Allied Health), examination of art…

Cervical paraspinal sarcopenia affects ability to achieve PROMIS minimal clinically important difference in patients undergoing anterior cervical discectomy and fusion.

INTRODUCTION: Sarcopenia is an established risk factor for poor outcomes in the general surgery literature; however, this has been less expl … interference (PI) scores were collected at baseline and 1-year postoperatively and compared with a minimal clinically important difference (MCID) of 4.5 for PF and 4.9 for PI. Bivariate and multivariate analyses compared FI and CSA in patients who met versus failed to meet the MCID for PF and PI components. RESULTS: Seventy-eight patients met the inclusion criteria. The mean age was 5 …

Minimal clinically important difference (MCID)-based analysis of single-versus two-level laminectomy for lumbar spinal stenosis: a prospective study.

AIM: To compare outcomes and minimal clinically important differences (MCID) between single-level laminectomy (SLL) and two-level laminectomy (TLL) for lumbar spinal stenosis (LSS). METHODS: This prospective study included 119 patients with confirmed LSS who underwent SLL or TLL at Cantonal Hospital Zenica from January 2018 to January 2025. Assessments were performed preoperatively and at 1 and 6 months postoperatively using the Oswestry Disability Index (ODI), Swiss Spinal Stenosis Questionnaire (SSSQ), and Visual Analogue Scale (VAS) for back and leg pain, along with evaluation of motor, se…

Defining the minimal clinically important difference in smartphone-based mobility after spine surgery: correlation of survey questionnaire to mobility data.

OBJECTIVE: Patient-reported outcome measures (PROMs) are the gold standard for assessing postoperative outcomes in spine surgery. However, P … y were assessed and compared between patients who did and those who did not achieve the established minimal clinically important difference (MCID) for each measure. RESULTS: A total of 31 patients receiving laminectomy (n = 21) or fusion (n = 10) were included. Change between preoperative and 6-week postoperative VAS and PROMIS-PI scores demonstrated moderate (r = -0.46) and strong (r …

Importance of achieving Scoliosis Research Society-22r minimal clinically important difference for improving patient satisfaction after adult spinal deformity surgery.

OBJECTIVE: Achievement of minimal clinically important differences (MCIDs) in the Scoliosis Research Society-22r (SRS-22r) subdomains represents surgical efficacy. However, whether achievements of MCIDs in SRS-22r domains are associated with long-term satisfaction in patients with adult spinal deformity (ASD) is unclear. This study aimed to elucidate factors affecting patient satisfaction after thoracopelvic corrective fusion surgery in patients with ASD. METHODS: Data obtained in 187 patients with ASD who underwent extensive corrective fusion surgery from the thoracic spine to the pelvis bet…

Editorial Commentary: Large Heterogeneity of Minimal Clinically Important Difference Utilization in Hip Arthroscopy Studies: Where Do We Go From Here?

The minimal clinically important difference is a relatively new method to evaluate outcomes after surgery, defined as the lowest value of change in the outcome score that results in a perceived clinical improvement. There is no clear delineation of use for this metric, resulting in a heterogeneous application in hip arthroscopy research, making comparisons with other studies difficult. Cohort-specific values calculated using an anchor-based method are best.

Risk Factors Associated With Failure to Reach Minimal Clinically Important Difference After Correction Surgery in Patients With Degenerative Lumbar Scoliosis.

STUDY DESIGN: A retrospective study. OBJECTIVE: The aim of this study was to evaluate the factors affecting health-related quality of life (HRQOL) after surgery in patients with degenerative lumbar scoliosis (DLS) by minimum clinically important difference (MCID). SUMMARY OF BACKGROUND DATA: MCID has been introduced in the adult spinal deformity to quantify the absolute minimum change that can be considered a success. There are limited data available to identify factors affecting reaching MCID after DLS surgery. METHODS: This study reviewed a cohort of 123 DLS patients after correction surg

Minimal Clinically Important Difference in Patient-Reported Outcome Measures with the Transforaminal Endoscopic Decompression for Lateral Recess and Foraminal Stenosis.

BACKGROUND: Patient-reported outcome measures (PROMs) have become widely used to better measure patients' judgment of treatment benefits from surgical spine care. The concept of determining the minimal clinically important differences (MCIDs) of PROMs is aimed at assessing the benefits of lumbar spine care that are meaningful to the patient. The goal of this study was to validate the utility of MCIDs of the visual analog score (VAS) and Oswestry Disability Index (ODI) in patients with sciatica-type low back and leg pain due to lateral recess and foraminal stenosis who were treated with directl…

Defining a minimal clinically important difference for the Vanderbilt ADHD Parent Rating Scale in children with Attention-Deficit/Hyperactivity Disorder.

BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition in children and adolescents that poses substantial challenges to health, functioning, and well-being. This study aimed to estimate the minimal clinically important difference (MCID) for the Chinese version of the Vanderbilt ADHD Parent Rating Scale (VAFPRS) and its key score domains using anchor-based and distribution-based methods. METHODS: In this multicenter prospective observational study, 99 children aged 4-17 years who were diagnosed with ADHD were recruited from four tertiary hospita…

Defining and validating the minimal clinically important difference for the cough severity visual analogue scale in adults with subacute cough.

BACKGROUND: Subacute cough imposes a significant burden, yet determining meaningful symptom relief remains challenging. While the cough severity visual analogue scale (VAS) is widely used, its minimal clinically important difference (MCID) is undefined for this population, limiting its utility in symptom management and clinical decision-making. OBJECTIVES: To establish the VAS MCID in adults with subacute cough, confirm its psychometric validity, and validate its utility in predicting clinical outcomes. METHODS: Individual patient data were analyzed from two randomized trials (N = 335) invol…