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Векторная динамика, лежащая в основе нынешнего и будущего появления в Европе вирусов, передаваемых через " тика " .

Болезни, передаваемые через тик, представляют все большую угрозу для здоровья человека и животных в Европе, при этом вирус энцефалита, передаваемый через тикали, и вирус геморрагической лихорадки Крыма-Конго (CCFV), вектором которых являются, соответственно, иксодес рицинус и маржатум гиаломмы, становятся основными проблемами в области общественного здравоохранения. Способность клещей передавать патогены на множество носителей и поддерживать инфекцию на всех этапах жизни делает их высокоэффективными векторами. Вместе с тем многие аспекты экологии и векторной способности клещей по-прежнему недо

Совпадение в аннотации оригинала
Tick-borne diseases pose a growing threat to human and animal health in Europe, with tick-borne encephalitis virus (TBEV) and Crimean-Congo haemorrhagic fever virus (CCHFV), vectored by Ixodes ricinus and Hyalomma marginatum, respectively, emerging as primary public health concerns. The ability of ticks to transmit pathogens to multiple hosts and maintain in…

Zoonotic Pathogens in Eurasian Beavers (Castor fiber) in the Netherlands.

Successful repopulation programs of Eurasian beavers (Castor fiber) have resulted in an increase in beaver populations throughout Europe. Th … e was positive for N. mikurensis. The latter finding indicates that beavers can be bitten by Ixodes ricinus and be exposed to tick-borne pathogens. The detected ESBL/AmpC-gene was blaCMY-2 in an Escherichia coli ST6599. The findings suggest that the role of beavers in the spread of zoonotic diseases in the Netherlands is currently limited.

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission.

During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick salivary compounds and tick-borne pathogens. However, the immunological consequences of tick feeding for human skin remain unclear. Here, we assessed human skin and blood samples upon tick bite and developed a human skin explant model mimicking Ixodes ricinus bites and tick-borne pathogen infection. Following tick attachment, we observed rapidly occurring patterns of immunomodulation, including increases in neutrophils and cutaneous B and T cells. T cells upregulated tissue residency markers, while lym…

Tick transmission of toxoplasmosis.

Introduction: Infection with Toxoplasma gondii (T. gondii) causes the disease toxoplasmosis in humans and animals. Oral transmission alone may not explain the widespread distribution of this parasite over large species of host animals and geographic areas.Areas covered: Limited studies indicate the potential role of ticks in the distribution of T. gondii. The possibility of transmission of T. gondii has been demonstrated in Dermacentor variabilis, Dermacentor andersoni, Amblyomma americanum, Dermacentor reticulatus, Ixodes ricinus, Ixodes amblyomma, Amblyomma cajennense, Ornithodorus moubata a…

Insight into diversity of bacteria belonging to the order Rickettsiales in 9 arthropods species collected in Serbia.

Rickettsiales bacteria in arthropods play a significant role in both public health and arthropod ecology. However, the extensive genetic div … pecies in this region. Furthermore, the high prevalence of spotted fever group Rickettsia in Ixodes ricinus ticks highlights the potential public health risk of human Rickettsia infection.

Granuloma Annulare and Morphea: Correlation with Borrelia burgdorferi Infections and Chlamydia-related Bacteria.

A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea histology from patients with suspected tick bite was perf … eneous and contained Waddliaceae and Rhabdochlamydiaceae bacteria, which are also present in Ixodes ricinus ticks, while the Chlamydiales sequences detected in morphea closely resembled those found in healthy skin. In conclusion, tick-mediated infections can trigger GA in some cases, while correlation of either Borrelia or Chlamydiales with morphea is unl …

[Borrelia miyamotoi: a recently identified human pathogenic tick-borne relapsing fever spirochete].

Borrelia miyamotoi is a recently described relapsing fever spirochete transmitted by ticks of the Ixodes ricinus complex. This pathogen is different from Borrelia burgdorferi sensu lato (the Lyme borreliosis spirochetes) in its epidemiology, ecology and also genetics. Over 50 patients have been described worldwide with Borrelia miyamotoi disease, and three immunocompromised patients were reported with neurological symptoms. Our knowledge about Borrelia miyamotoi infection in ticks and its distribution in different habitats and also the mechanism of the infection is limited. The most common sym…

A seventeen-year epidemiological surveillance study of Borrelia burgdorferi infections in two provinces of northern Spain.

This paper reports a 17-year seroepidemiological surveillance study of Borrelia burgdorferi infection, performed with the aim of improving o … ticulatus (11.76%), Rhiphicephalus sanguineus (17.64%), Rhiphicephalus turanicus (5.88%) and Ixodes ricinus (23.52%). B. burgdorferi DNA was sought by PCR in ticks when available. One tick, a D. reticulatus male, was found carrying the pathogen. The seroprevalence found was similar to the previously demonstrated in similar studies in Spain and other Europ …

Prevalence of ectoparasitic arthropods on wild animals and cattle in the Las Merindades area (Burgos, Spain).

This paper reports the prevalence of ectoparasitic arthropods in sampled groups of wild (n = 128; 16 species) and domestic (n = 69; 3 species) animals in the Las Merindades area of the Province of Burgos, Spain. The study revealed that wild animals were more infested and with a wider variety of ectoparasites than domestic animals. The parasitic prevalence was 67% for wild animals and 48% for livestock. In this way, 39% of animals were infected by ticks. Ixodes ricinus and Ixodes hexagonus were the most prevalent species whereas Dermacentor reticulatus showed affinity for the fox and wolf. The …

Multisystem organ failure after large volume injection of castor oil.

We report a case of multisystem organ failure after large volume subcutaneous injection of castor oil for cosmetic enhancement. An unlicense … ring dialysis for an additional 1.5 months. Castor oil absorption was inferred from recovery of the Ricinus communis biomarker, ricinine, in the patient's urine (41 ng/mL). Clinicians should anticipate multiple complications after unapproved methods of cosmetic enhancement.

Migratory passerine birds as reservoirs of Lyme borreliosis in Europe.

To define the role of birds as reservoirs and disseminators of Borrelia spirochetes, we characterized tick infestation and reservoir competence of migratory passerine birds in Sweden. A total of 1,120 immature Ixodes ricinus ticks were removed from 13,260 birds and assayed by quantitative polymerase chain reaction (PCR) for Borrelia, followed by DNA sequencing for species and genotype identification. Distributions of ticks on birds were aggregated, presumably because of varying encounters with ticks along migratory routes. Lyme borreliosis spirochetes were detected in 160 (1.4%) ticks. Borreli…

Screening of plants acting against Heterometrus laoticus scorpion venom activity on fibroblast cell lysis.

The aqueous extracts of 64 plant species, listed as animal- or insect-bite antidotes in old Thai drug recipes were screened for their activi … ae), Passiflora laurifolia L. (Passifloraceae), Plectranthus amboinicus (Lour.) Spreng. (Labiatae), Ricinus communis L. (Euphorbiaceae), Rumex sp. (Polygonaceae) and Sapindus rarak DC. (Sapindaceae), indicating that they had a tendency to be scorpion venom antidotes. However, only Andrographis paniculata and Barringtonia acutangula extracts provided aroun …

[The entomological and acarological situation in Nizhegorod Province].

Ixodes, persulcatus, I. ricinus, D. reticulatus, D. marginatus, H. concinna were recorded in different regional environmental regions. The northern districts of the region are endemic for tick-borne encephalitis (TBE) and Ixodes tick-borne borreliosis (ITBB). The infection of ticks with TBE virus is 0.25%, that with Borrelia is 10.3% of the total number of the examinees. In 1997 TBE and TTBB morbidity rates were 1.91 and 2.0 per 100,000, respectively. Data on the phenology of prevailing Anopheles messeae are given. Human malaria contamination may take 99-102 days (the first ten days of June to…

Human babesial infections in Europe.

The tick transmission of Babesia from infected animals to human has been clearly demonstrated. Including the first case described by Skaraballo in 1957 in Yugoslavia, 22 cases of human babesiosis have been reported in Europe. B. divergens, which is the most common pathogen for cattle, was involved in 17/22 cases. France, British Isles and Ireland accounted for more than half of the cases, occurring especially between May and October, the period of maximal activity of Ixodes ricinus, considered as the major vector. Splenectomy was the main factor of risk which was found in 86% of the patients. …

Amplifying role of edible dormice in Lyme disease transmission in central Europe.

To determine whether the presence of edible dormice (Glis glis) amplifies the risk of human infection by the Lyme disease spirochete (Borrelia burgdorferi), the capacity of dormice as reservoir hosts was compared with that of other potential reservoirs in a central European site where risk of human infection is intense. Dormice appeared to be more heavily infested by subadult vector wood ticks (Ixodes ricinus) than were other reservoir hosts. Although their spirochete competence was similar to other reservoir hosts, field-derived dormice infected more ticks than did other rodents in the site, …

Lectin-cytochemical study on epithelial mucus glycoprotein of conjunctiva and pterygium.

The epithelium of pterygium and conjunctiva was studied with reference to cytochemical reactivity to six fluorescein-labeled lectins that recognize a certain carbohydrate residue(s) of cellular membrane-bound or secretory glycoprotein: Ulex europaeus agglutinin-1 (UEA-1, specific for fucose); Dolichos biflorus agglutinin (DBA, specific for N-acetylgalactosamine); peanut agglutinin (PNA, specific for galactose-beta 1-3N-acetylgalactosamine): wheat germ agglutinin (WGA, specific for N-acetylglucosamine and N-acetylneuraminic acid); Concanavalia ensiformis (Con A, specific for mannose); Ricinus c…

Lectin binding to normal, dysplastic, and neoplastic cervical epithelium.

Avidin-biotin-peroxidase labeling technic was used to localize the binding sites of Concanavalin agglutinin (Con A), Ricinus communis (RCA-I), Ulex europaeus (UEA-I), and Limus flafus (LFA) in the cervical epithelia afflicted with condyloma (2 cases), moderate dysplasia (6), severe dysplasia (3), carcinoma in situ (9), squamous cell carcinoma (18), adenosquamous carcinoma (2), adenocarcinoma (1), and glassy cell carcinoma (1). Normal squamous epithelium displayed binding sites predominantly located on the cellular membranes for all the tested lectins except UEA. Normal glandular epithelium sho…

[Clinical aspects and etiology of acrodermatitis chronica atrophicans].

We followed up nine patients with acrodermatitis chronica atrophicans (ACA) for an average of 2 years (6-44 months). Extradermal symptoms we … nd insignificant IgM antibody titers; similar results were obtained in some patients when an Ixodes ricinus spirochete isolated in the area of Munich was used as antigen. We believe that ACA is a chronic spirochetosis with manifestations present in the skin, joints, nervous system, and presumably in the heart.

Reactivity of isolated lipopolysaccharides of enterobacterial R mutants with complete or incomplete core structures with lectins.

Alkali-treated lipopolysaccharides of a range of enterobacterial R mutants with complete and incomplete core structures were investigated by agar gel and microcapillary precipitation onto their reactivity with three selected commercial lectins, namely Concanavalin A, Ricinus communis agglutinin and Wheat germ agglutinin. R lipopolysaccharides with complete R cores of the six so far established core types were differentiable from each other by their characteristic lectin reactivity pattern. One core type showed no reaction with all the three lectins. R lipopolysaccharides with incomplete core s…

Prevalence of Hepatozoon canis infection in dogs from the area of Lublin Voivodship.

Canine hepatozoonosis is a tick-borne protozoal disease. Two species of Hepatozoon may infect dogs: Hepatozoon americanum and H. canis. The … ith their owners in Turkey (group 2). DNA of H. canis was detected in 1 dog in group 1 (with Ixodes ricinus infestation), and in 2 dogs in group 2 (with Ripicephalus sanguineus infestation). The results obtained indicate that infections with H. canis should be taken into account and included in the differential diagnosis of vector-borne diseases in dogs i …