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A Case of Idiopathic Pulmonary Hemosiderosis Presenting With Signs and Symptoms Mimicking Hemolytic Anemia.

Idiopathic pulmonary hemosiderosis is primarily a disorder of childhood, which is characterized by hemoptysis, iron deficiency anemia, and diffuse parenchymal infiltrates on chest x-ray secondary to recurrent attacks of alveolar hemorrhage. It can be diagnosed by showing hemosiderin laden macrophages in bronchoalveolar lavage fluid after other specific causes of diffuse alveolar hemorrhage are definitely excluded. A 5-year-old male patient was admitted to our clinic with sudden-onset pallor during iron therapy given for anemia. While he was being investigated for clinical and laboratory signs …

Renal artery stenosis: An unusual etiology of hypertensive encephalopathy in a child with fanconi anemia.

A 9-year-old girl, diagnosed case of Fanconi anemia, presented with generalized convulsion with altered sensorium. She had fever, severe pallor, sinus tachycardia, blood pressure of 180/120 mmHg in both upper and lower limb, pan-systolic murmur of grade 2/6, abdominal bruit and bilateral papilledema. A provisional diagnosis of hypertensive encephalopathy was made and managed with continuous labetalol infusion. Detailed evaluation including magnetic resonance angiography of renal artery detected underlying atrophic and non-functioning right kidney secondary to severe renal artery stenosis on th…

A rare type of Usher's syndrome.

A case is presented of a very rare type of Usher's syndrome detected in a 30-year-old woman in her 28th week of pregnancy. She reported left eye visual impairment with a one-month history. She underwent standard ophthalmologic examination with additional procedures scheduled after childbirth, including fluorescein angiography, visual field (Goldman and Octopus) and electroretinography. Fundus examination revealed pallor of the optic disk, diffuse retinal blood vessel narrowing, no retinal pigmentation, left macular edema, vitreous liquefaction, and posterior vitreous detachment. Goldman perime…

Tumefactive demyelination-to cracks the nut without cracking the pot.

A 45-year-old female recently detected diabetic, admitted with difficulty in walking, irrelevant talk and urinary incontinence for 3 weeks and deviation of angle of mouth to left. Examination revealed pallor, delusional thoughts, right upper motor neuron facial weakness, ataxia. CT brain revealed bulky hyperdense lesion in corpus callosum and subsequently MRI of the brain revealed T2-hyperintense lesions involving genu and body of corpus callosum with restricted diffusion, and MR spectroscopy revealed reduced uptake of choline. Possibilities considered were infiltrative glioma of corpus callos…

Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis.

Syphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor and sheathing of vessels on fundoscopy. A diagnosis of probable endogenous endophthalmitis was made and vitreous tap performed. Vitreous biopsy showed no growth of fungus or bacteria. Rapid plasma reagin (RPR) and Treponema pallidum hemagglutination (TPHA) test were positive. Enzyme-Linked Immuno Sorb…

[Clinical observation of Flos magnoliae volatile oil nano-liposome nasal drops in treating pediatric allergic rhinitis].

OBJECTIVE: To observe the clinical efficacy of Flos Magnoliae volatile oil nano-liposome nasal drops (FMO) in treating pediatric allergic rh … fective rate on alleviating main symptoms (sneezing, nasal obstruction), signs (nasal mucosa edema, pallor) and the EOS count were significantly lowered, all were better than those in the control group (P <0.05). CONCLUSION: FMO has some positive effects on PAR, it might be realized by lowering the peripheral EOS.

ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy.

We report 3 cases of a previously uncharacterized form of histiocytosis presenting in early infancy and showing ALK immunoreactivity. The patients presented with pallor, massive hepatosplenomegaly, anemia, and thrombocytopenia. Liver biopsy showed infiltration of the sinusoids by large histiocytes with markedly folded nuclei, fine chromatin, small nucleoli, and voluminous lightly eosinophilic cytoplasm that sometimes was vacuolated or contained phagocytosed blood cells. One patient developed cutaneous infiltrates that morphologically resembled juvenile xanthogranuloma. The histiocytes were imm…

Clinical predictors of bioterrorism-related inhalational anthrax.

Limitation of a bioterrorist anthrax attack will require rapid and accurate recognition of the earliest victims. To identify clinical characteristics of inhalational anthrax, we compared 47 historical cases (including 11 cases of bioterrorism-related anthrax) with 376 controls with community-acquired pneumonia or influenza-like illness. Nausea, vomiting, pallor or cyanosis, diaphoresis, altered mental status, and raised haematocrit were more frequently recorded in the inhalational anthrax cases than in either the community-acquired pneumonia or influenza-like illness controls. The most accurat…

Resurgence of malaria in Calcutta in 1995: a hospital based study.

A total of 405 cases of fever who were either admitted to the Hospital or attended in paediatric out patient Department or Emergency of Medical College Hospital, Calcutta between January '95 and November '95 were included in the study. Majority of cases presented with usual features of malaria like fever with chill and rigor, hepatosplenomegaly, pallor. Apart from these, complicated manifestations like shock, convulsion D.I.C and jaundice were also observed. Some unusual presentations with severe diarrhoea, dehydration and features like that of acute viral respiratory tract infection were high…

Human herpesvirus-6 associated hemophagocytic syndrome in beta-thalassemia: report of one case.

An 8-month-old male infant with severe anemia and thrombocytopenia was brought to our hospital due to fever and pallor. The physical examination on admission showed pale conjunctivae, skin rash, lymphadenopathy and hepatosplenomegaly. Subsequent laboratory studies showed pancytopenia, impaired liver function, elevated lactate dehydrogenase level but without evidence of disseminated intravascular coagulation. Bone marrow aspiration demonstrated increased macrophages and prominent hemophagocytosis. The serological studies revealed a recent infection of human herpesvirus-6 which was confirmed by …

Visual and vestibular components of motion sickness.

BACKGROUND: The relative importance of visual and vestibular information in the etiology of motion sickness (MS) is not well understood, but these factors can be manipulated by inducing Coriolis and pseudo-Coriolis effects in experimental subjects. HYPOTHESIS: We hypothesized that visual and vestibular information are equivalent in producing MS. The experiments reported here aim, in part, to examine the relative influence of Coriolis and pseudo-Coriolis effects in inducing MS. METHODS: We induced MS symptoms by combinations of whole body rotation and tilt, and environment rotation and tilt,

Effects of different turn intervals on skin of healthy older adults.

A comparison of the effects of one-, one and a half-, and two-hour turning intervals on changes in the skin surface temperature, interface pressure, and color was conducted on 16 older, healthy adults. Both trochanters and the sacrum were the sites used for measurement. Findings indicated that the greatest increase in skin surface temperature occurred at the end of the two-hour turning interval and in the trochanteric positions. No significant differences in interface pressure were found with respect to the length of the turning interval or body position. A descriptive summary of changes in sk

Paediatric necrotising pancreatitis.

Necrotising pancreatitis is a rare but serious complication of acute pancreatitis in children. We report a case of a toddler who presented with a 1 day history of persistent non-bilious vomiting, intermittent pallor and irritability, without fever or diarrhoea. Initial examination was non-specific, but progressive abdominal tenderness and new onset of fever prompted imaging and laboratory investigations. Elevated inflammatory markers and serum lipase, along with contrast-enhanced CT findings, confirmed a diagnosis of necrotising pancreatitis. The patient was transferred to a tertiary hospital,…

Двойная автономность: синдром Эванса и множественный склероз.

Синдром Эванса (ES) — редкое аутоиммунное расстройство, связанное с аутоиммунной гемолитической анемией и иммунной тромбоцитопенией (ИТП). Пациенты, как правило, страдают от петехии, пурпуры, паллора и усталости. Диагностические критерии включают в себя положительное прямое антиглобулиновое испытание, ретикулокитоз, снижение уровня гаптоглобина, а также повышенный косвенный уровень билюродина и лактата дегидрогеназы. ЭУ может быть связано с другими аутоиммунными заболеваниями, включая системный волчанки эритематос, ревматоидный артрит и аутоиммунный гепатит. Вместе с тем в научной литературе в

Совпадение в аннотации оригинала
Evans syndrome (ES) is an uncommon autoimmune disorder associated with autoimmune hemolytic anemia and immune thrombocytopenia (ITP). Patients generally present with petechiae, purpura, pallor, and fatigue. Diagnostic criteria include a positive direct antiglobulin test, reticulocytosis, decreased haptoglobin, and elevated indirect bilirubin and lactate dehy…

Necrotizing eyelid fasciitis - Series of two cases and three eyelids.

Necrotising eyelid inflammation, also known as necrotising fasciitis (NF) of the orbit, is a rare but severe soft tissue infection. Prompt and appropriate treatment is crucial, as delayed intervention can result in the bacteria entering the bloodstream. Typical predisposing factors for NF include skin breaks after surgery or trauma, which may be small and overlooked. NF is mainly caused by group A beta-haemolytic streptococci, with significant cases also attributed to Pseudomonas aeruginosa and Staphylococcus aureus.Symptoms include swelling, fever and pallor in the orbital region. Untreated N…

Right-sided aortic arch with anomalous coronary artery origin and concomitant Stanford type A dissection: A rare case report.

Congenital anomalies of the aortic arch are rare and may be incidentally discovered or present with life-threatening complications. We report a case of a 58-year-old man with hypertension and a remote history of smoking, who presented with sudden, severe chest pain radiating to the back, hypotension, tachycardia, and pallor. Bedside ultrasound revealed moderate pericardial effusion and raised suspicion of aortic dissection. ECG-gated CT angiography (CTA) confirmed a Stanford type A aortic dissection with a right-sided aortic arch (RAA) and anomalous origin of the right coronary artery from the…

Bilateral Sequential Ocular Vascular Occlusions With Subsequent Unilateral Acute Retinal Necrosis in a Patient With HIV Infection.

Purpose: To report a case of bilateral ocular vascular occlusion with subsequent development of unilateral acute retinal necrosis in a patient with HIV infection. Methods: A single case was evaluated. Results: A 40-year-old woman presented with a sudden decrease in vision in the right eye for a 1-month duration. Disc pallor, arteriolar attenuation, and blot hemorrhages were seen in the midperiphery of the fundus of the right eye. On follow-up, the patient presented with reduced vision in the left eye for a 10-day duration. A fundus examination of the right eye showed extensive retinitis patche…