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Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators.

This study aims to systematically assess the therapeutic effectiveness of TiRobot-assisted percutaneous kyphoplasty or vertebroplasty in managing osteoporotic thoracolumbar compression fractures. Previous studies have suggested that TiRobot-assisted techniques outperform conventional manual procedures in treating this condition, but relevant conclusions remain controversial. A thorough literature retrieval was carried out across 4 major databases: PubMed, Embase, the Cochrane Library, and Web of Science. The final search was completed on July 20, 2025. After applying specific inclusion and exc…

Prognostic nutritional index and modified frailty index, independent risk factors for recompression in elderly patients with osteoporotic vertebral compression fractures.

BACKGROUND: To identify some clinical and laboratory independent risk factors for postoperative recompression among elderly osteoporotic vertebral compression fractures (OVCF) patients. METHODS: A retrospective analysis was conducted on 287 elderly OVCF patients after percutaneous vertebroplasty (PVP). Relevant risk factors for recompression were screened and further analyzed through multivariate logistic regression. RESULTS: Within postoperative 1 year, recompression had occurred in 72 patients, with an incidence of 25.1% (72/287). Multivariate logistic analysis indicated that mean spinal B

Occurrence of adjacent segment fractures after surgical treatment of an osteoporotic vertebral fracture: a retrospective comparison between two different treatment methods.

INTRODUCTION: Osteoporotic vertebral fractures are a major healthcare problem. Vertebral cement augmentation (VCA) is frequently used as a minimally invasive surgical approach to manage symptomatic fractures. However, there is a potential risk of adjacent segment fracture (ASF), which may require second surgery. The addition of transcutaneous screw-fixation with cement augmentation superior and inferior to the fracture [Hybrid transcutaneous screw fixation (HTSF)] might represent an alternative treatment option to reduce the incidence of ASF. MATERIALS AND METHODS: We retrospectively compared

[Diagnostics and treatment of osteoporotic vertebral fractures].

Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with vertebr … ections, patients have to be treated with percutaneous vertebroplasty (PVP) or percutaneous balloon kyphoplasty (BKP). PVP is a minimally invasive surgical procedure in which bone cement is injected into a fractured vertebra under radiological guidance using fluoroscopy. BKP is a variation of this approach, in which an inflatable balloon tamp is placed in the …

Treatment-dependent association between sarcopenia and ADL at discharge after osteoporotic vertebral fractures.

INTRODUCTION: Sarcopenia has been associated with lower activities of daily living (ADL). This study investigated whether sarcopenia at admission is associated with ADL at discharge in patients with osteoporotic vertebral fractures (OVF) and whether this differs by treatment (conservative or balloon kyphoplasty, BKP). MATERIALS AND METHODS: This prospective cohort study included 78 patients with OVF (76.8% female; mean age 83.0 ± 6.7 years). Sarcopenia was defined according to the 2019 Asian Working Group for Sarcopenia criteria, requiring low skeletal muscle mass and low handgrip strength. T…

Extended uses of robots in spine surgery beyond thoracolumbar pedicle screws: A narrative review.

Robotic assistance in spine surgery has matured considerably over the past two decades, with its initial role confined largely to thoracolum … , particularly S2 alar-iliac screw placement; (3) vertebral augmentation, including vertebroplasty, kyphoplasty, and sacroplasty; (4) biopsy and targeted puncture workflows; and (5) anterior and lateral interbody fusion approaches. For each category, we review the available evidence on accuracy, safety, clinical outcomes, and technical considerations. Across …

Differentiating benign from malignant vertebral fractures using T1 -weighted dynamic contrast-enhanced MRI.

PURPOSE: To differentiate pathologic from benign vertebral fractures, which can be challenging. We hypothesized that dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can aid in the noninvasive distinction between pathologic and benign fractures. MATERIALS AND METHODS: Consecutive patients with vertebral fractures who underwent DCE-MRI, biopsy, and kyphoplasty were reviewed. Forty-seven fractures were separated into pathologic and benign fractures. Benign fractures were in turn separated into acute and chronic fractures for further comparison. Regions of interest (ROIs) were plac…

Major surgical treatment of osteoporotic vertebral fractures in the elderly: a comparison of anterior spinal fusion, anterior-posterior combined surgery and posterior closing wedge osteotomy.

STUDY DESIGN: A retrospective study. PURPOSE: To clarify the differences among the three major surgeries for osteoporotic vertebral fractures based on the clinical and radiological results. OVERVIEW OF LITERATURE: Minimally invasive surgery like balloon kyphoplasty has been used to treat osteoporotic vertebral fractures, but major surgery is necessary for severely impaired patients. However, there are controversies on the surgical procedures. METHODS: The clinical and radiographic results of patients who underwent major surgery for osteoporotic vertebral fracture were retrospectively compar…

Myeloma bone disease and treatment options.

Multiple myeloma (MM) is a B-cell malignancy characterized by enhanced bone loss commonly associated with a diffuse osteopenia, focal lytic … bone disease in molecular level. The development of minimally invasive surgical procedures such as kyphoplasty and vertebroplasty allows myeloma patients with vertebral compression fractures to have immediate improvement in quality of life and shorter hospital stays. Monthly intravenous infusion of either pamidronate or zoledronic acid have reduced the skele …

Fracture and Vertebral Augmentation Utilization Following Androgen Deprivation Therapy in Men With Prostate Cancer: A Propensity Score-matched Cohort Study.

Study DesignRetrospective cohort study.ObjectiveTo investigate the association between androgen deprivation therapy (ADT), vertebral compression fracture (VCF) incidence, and subsequent vertebral augmentation (vertebroplasty/kyphoplasty) utilization in adult men with prostate cancer.MethodsAdult men with prostate cancer were stratified by ADT exposure and matched 1:1 to non-ADT controls on demographics, comorbidities, and bone health. Primary outcomes were VCF incidence at 3 months, 1 year, 3 years, and 5 years and vertebral augmentation utilization. Secondary outcomes included posterior spina…

Risk factors for subsequent vertebral fractures after percutaneous vertebral augmentation in Asian populations: a systematic review and meta-analysis.

OBJECTIVE: To identify the risk factors for subsequent vertebral fractures after percutaneous vertebral augmentation through the meta-analys … tebral fracture, postoperative Cobb angle, surgical method（percutaneous vertebroplasty/percutaneous kyphoplasty）, puncture method (unilateral/bilateral puncture), or bone cement volume. CONCLUSION: In Asian populations, advanced age, female, low T-score, low BMI, low CT HU values, presence of IVC, multi-segment vertebral fractures, and bone cement leakage ar …

Улучшается прогноз по множественным болезням кости миэломы: анализ ретроспективного анализа хирургических операций.

Множественная миелома (ММ) — гематологическая порча, характеризующаяся инфильтрацией костного мозга и формированием остеолитической опухоли. Несмотря на успехи в лечении этого заболевания, ММ остается неизлечимым и часто приводит к осложнениям, таким, как множественные заболевания костей миэломы (ММБД). Для борьбы с симптомами, связанными с болезнью костей, включая боль и переломы, часто необходимо хирургическое вмешательство. 135 у пациентов с диагнозом MMBD, которые прошли операцию, по сравнению с 190 у пациентов с диагнозом MM, которые не прошли хирургическую операцию и служили в качестве к

Совпадение в аннотации оригинала
BackgroundMultiple myeloma (MM) is a hematological malignancy characterized by bone marrow infiltration and osteolytic tumor formation. Desp … related bone disease, as indicated by imaging results. Patients who had only undergone percutaneous kyphoplasty or vertebroplasty (PKP/PVP) were excluded from this study.ResultsAmong patients who underwent surgery, the spine was the most common site of bone metastasis, accounting for 50% of cases. The number of operations (overall survival [OS], p = 0.82; pro …

Value of bone scan imaging in determining painful vertebrae of osteoporotic vertebral compression fractures patients with contraindications to MRI.

OBJECTIVE: To assess the value of bone scan imaging in determining painful vertebrae of osteoporotic vertebral compression fractures (OVCFs) … and bone scan to determine painful vertebrae. After the painful vertebra was defined, percutaneous kyphoplasty (PKP) was performed. Efficacy of PKP was assessed with visual analog (VAS) pain scale and the Oswestry Disability Index (ODI) preoperatively, postoperatively and during final follow-up assessments. RESULTS: The painful vertebrae shown on radiologic …

Does timing matter? A single-institution analysis of vertebral augmentation before or after radiotherapy in the treatment of painful spine metastases.

OBJECTIVE: Vertebral augmentation (VA), including vertebroplasty and kyphoplasty, has become pivotal in alleviating pain and disability associated with pathological compression fractures of the spine. However, there is no existing guidance informing the ideal timing of radiotherapy (RT) and VA, with a theoretical concern of tumoral seeding if adjuvant. This study compared locoregional cancer recurrence in patients who underwent neoadjuvant versus adjuvant RT. METHODS: The authors conducted a retrospective review of all adult cancer patients treated with VA and RT within 3 months between 2009 …

Usefulness of MRI in determining the appropriate level of cement augmentation for acute osteoporotic vertebral compression fractures.

STUDY DESIGN: This is a prospective study on consecutive patients with acute osteoporotic vertebral compression fractures (OVCFs). OBJECTIVES: To evaluate the usefulness of magnetic resonance imaging (MRI) for diagnosing appropriate acute lesions before a percutaneous cement augmentation technique. BACKGROUND: Vertebral compression fractures related to osteoporosis are very common in the elderly. Acute OVCFs are usually treated conservatively. In recent years, minimally invasive percutaneous cement augmentation techniques, vertebroplasty and kyphoplasty, have been introduced as alternative t…

Effects of robot-assisted minimally invasive surgery on osteoporotic vertebral compression fracture: a systematic review, meta-analysis, and meta-regression of retrospective study.

OBJECTIVE: To conduct a systematic review on the effect of robot-assisted minimally invasive surgery (R-MIS) on the clinical outcomes and complications of patients with osteoporotic vertebral compression fractures (OVCFs). METHODS: The researchers searched the papers published on PubMed, The Cochrane Library, Web of Science, Embase, Scopus, Ovid MEDLINE, Wiley Online Library, China National Knowledge Infrastructure (CNKI), Chinese biomedical literature service system (SinoMed), and China Medical Association Data. The standardized mean difference (SMD) or mean difference (MD), relative risk (R

Double Vertebrae Kümmell Disease: Five Cases Report and Literature Review.

Kümmell disease (KD) is a complication of osteoporotic vertebral compression fractures. There is a lot of literature on KD, but the reported cases are all single vertebrae. This study reports five double vertebrae KD cases (10 levels) and discusses the possible underlying mechanisms with a literature review. One hundred and thirty vertebrae KD were diagnosed from 2074 osteoporotic vertebral compression fractures patients treated in our hospital between 2015 and 2019. These vertebrae KD were divided into two groups, one-level vertebrae KD (n = 125) and double-level KD (n = 5). The diagnosis of

Practice Patterns of Percutaneous Vertebroplasty: A Survey of Neurosurgeons.

AIM: To characterize current vertebral augmentation practices among neurosurgeons in Türkiye, with particular emphasis on patient selection, … was primarily guided by pain severity and MRI-based fracture acuity. Support for vertebroplasty or kyphoplasty was highest for acute or subacute painful osteoporotic fractures refractory to conservative treatment. In contrast, support was lower for patients with chronic and traumatic fractures without neurologic deficit. Technical practice was relatively uni …

Intracardiac bone cement embolism and cardiac injury: a systematic review of 116 reported cases.

BACKGROUND: Intracardiac bone cement embolism (BCE) is a rare but potentially serious complication of spinal augmentation. Clinical awarenes … ent age was 69 years, and 75.9% were female. Most embolic events followed vertebroplasty (67.2%) or kyphoplasty (26.7%). Chest pain (59.5%) and dyspnea (54.3%) were the most common symptoms. Diagnostic yield was high for echocardiography (96.0%) and computed tomography (CT) (93.8%) but lower for chest X-ray (63.4%). Linear cement fragments were frequently ass …