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Prospective Cardiac MRI study comparing Recovered COVID-19 patients with Recovered Non-COVID-19 Viral Respiratory Infection Patients (R-COVID-CMR).

OBJECTIVE: Coronavirus disease 2019 (COVID-19) has been associated with subclinical myocardial inflammation. Post-COVID-19 infection, there … nfluenza virus, rhinovirus/enterovirus, parainfluenza virus, respiratory syncytial virus, and human metapneumovirus. At all three time points, blood results and cardiac function parameters were not significantly different between RCOVID and non-COVID patient groups (p-value not significant). Both patient groups had no significant differences for native T1/T2 valu …

[Investigation of viral respiratory tract infection agents by multiplex PCR method in autopsy cases: A five-year study].

Viral respiratory infections are one of the leading causes of morbidity and mortality, especially in children, elderly and immunocompromised … virus (EV), human bocavirus (HBoV), adenovirus (AdV), human coronavirus (HCoV 229,63,HKU,43), human metapneumovirus A ve B (HMPV-A/B), parechovirus, respiratory syncytial virus (RSV A/B) and Mycoplasma pneumoniae. In our study, at least one respiratory virus was detected by Rt-PCR in 379 (45.4%) of total 834 cases, whereas no viral agent was identified in 455 (54 …

[Simultaneous detection of respiratory viruses and influenza A virus subtypes using multiplex PCR].

This study was conducted to investigate the respiratory viruses and subtyping of influenza A virus when positive by multiplex PCR in patient … respiratory viruses [Adenovirus, parainfluenza virus (PIV) types 1-4, human bocavirus (HBoV), human metapneumovirus (HMPV), rhinovirus types A and B, human coronaviruses (HCoV) OC43, 229E/NL63] were investigated with those tests. In the study, 53.6% (375/700) of the patients were found to be infected with at least one virus and multiple respiratory virus infectio …

[Etiology of acute respiratory tract infection in hospitalized children in Suzhou from 2005 to 2011].

OBJECTIVE: To elucidate the etiology of acute respiratory tract infection (ARI) in hospitalized children in Suzhou from 2005 to 2011. METHO … moniae (MP) and chlamydia pneumoniae (CP) were detected by fluorescent quantitative PCR while human metapneumovirus (hMPV) was detected by reverse transcription PCR (RT-PCR). Sputum culture was applied to detect bacterial infection and quantitative ELISA was adopted to detect the specific antibodies of MP and CP. The results of the above detections were analyzed, …

Dynamics of respiratory virus transmission in children during and after COVID-19 outbreak control in Baiyin, China.

PURPOSE: We aimed to study the changes in respiratory virus detection rates during the control of the COVID-19 outbreak and to elucidate pos … respiratory syncytial virus (HRSV), human rhinovirus (HRV), human parainfluenza virus (HPIV), human metapneumovirus (HMPV), human adenovirus (HADV), enterovirus (EV), and human coronavirus (HCoV). The results were statistically analyzed using SPSS 26.0 software. RESULTS: A total of 1353 nasopharyngeal swab specimens were collected from children with SARI between …

PB2575: HIGH INCIDENCE OF RESPIRATORY TRACT INFECTIONS FOLLOWING COVID-19 WAVES IN PATIENTS WITH PLASMA CELL DYSCRASIAS

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… Positive swabs detected different viruses: 4 Coronavirus OC43/HKV1, 1 Influenza A, 3 Metapneumovirus, 3 parainfluenza, 8 rhinovirus and 11 respiratory syncytial virus (RSV). … There were 5 RSV co-infections with rhinovirus (2) and 1 each for metapneumovirus, Coronavirus OC43/HKV1 and parainfluenza and 3 RSV-superinfection (2 pulmonary aspergillosis, 1 bacterial pneumonia). 28 cases (93%) of RTI were mild and did not require hospitalization. 2 pts with RSV upper RTI (URTI) …

Characteristics and Outcomes of Patients With Hematologic Malignancies Hospitalized With Respiratory Viral Infections.

BackgroundRespiratory viral infections in patients with hematologic malignancies or hematopoietic stem cell transplants (HCTs) are associated with increased morbidity and mortality. However, the hospital presentations and courses of these infections remain under-described.MethodsWe performed a multicenter retrospective cohort study of hospitalized patients with hematologic malignancy or HCT at 2 comprehensive cancer centers between January 2019 and June 2023. We included all patients with acute viral respiratory infection (identified based on a constellation of test results and objective physi

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… Respiratory syncytial virus, human metapneumovirus, and Parainfluenza virus infections in lung transplant recipients: a systematic review of outcomes and treatment strategies. Clin Infect Dis 2022; 74:2252–60. 45. Pérez A, Gómez D, Montoro J, et al. … A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis 2005; 192:1061–5. 62. Martino R, Porras RP, Rabella N, et al. …

Severe infections and infection-related mortality in a large series of haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide.

Severe infections and their attributable mortality are major complications in recipients of allogeneic hematopoietic stem cell transplantation (alloSCT). We herein report 236 adult patients who received haploSCT with PTCy. The median follow-up for survivors was 37 months. The overall incidence of bloodstream infections by gram-positive and gram-negative bacteria at 37 months was 51% and 46%, respectively. The incidence of cytomegalovirus infection was 69%, while Epstein Barr virus infections occurred in 10% of patients and hemorrhagic cystitis in 35% of cases. Invasive fungal infections occurr

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… ESBL Escherichia coli 1 Pseudomonas aeruginosa 1 Multidrug resistance Pseudomonas aeruginosa 1 1 1 Klebsiella pneumoniae 2 ESBL or KPC Klebsiella pneumoniae 1 1 Acinetobacter baumannii 1 Stenotrophomonas maltophila 1 Serratia marcescens 1 Viral infection (N 7) 1 3 3 CMV disease (pneumonitis) 1 2 1 Metapneumovirus … Only one patient died as a consequence of metapneumovirus pneumonia. Upper (URTI) and lower (LRTI) respiratory tract infections by a CRV accounted for 34 and 28 episodes (55% and 45%), respectively (details shown in Table 4 ). …

Incidence and Diagnostic Evaluation of Postoperative Fever in Pediatric Patients With Neuromuscular Disorders.

BACKGROUND: Children with neuromuscular disorders have a significant chance of developing scoliosis and/or hip dislocation during childhood … eal aspirate culture 0/1, throat culture 1/1, adenovirus polymerase chain reaction (PCR) 0/5, human metapneumovirus PCR 0/5, parainfluenza PCR 0/5, rhinovirus PCR 0/1, 1/3 bronchoalveolar culture, and 0/7 respiratory virus panel. A total of 37 blood cultures were drawn and all were negative. There was a significant difference (P=0.04) in frequency of negative dia …

Evaluating Changes in The Clinical Presentation of Acute Obstructive Bronchitis in Preschool Children Using Antiviral Therapy.

UNLABELLED: A randomized double-blind controlled study was carried out to evaluate changes in the clinical presentation of acute obstructive … rmore, RNA of influenza B virus, respiratory syncytial virus, parainfluenza virus types 2 and 4 and metapneumovirus were also detected; 3 children in each group simultaneously had RNA of various viruses; no differences between the groups were observed. In group 1 average duration of increased body temperature (morning measurement) was 1.6 (1.4-1.9)±0.6 days, resp …

[Determination of the frequency of human bocavirus and other respiratory viruses among 0-2 years age group children diagnosed as acute bronchiolitis].

Acute bronchiolitis, mostly seen in infants and younger children, is a lower respiratory tract infection frequently caused by viral agents. … e detection of respiratory viruses [respiratory syncytial virus (RSV) A & B; rhinovirus (RV); human metapneumovirus (hMPV) A & B; influenza virus type A [H1N1, H3N2, H1N1v], B & C; parainfluenza virus (PIV) type 1, 2, 3 & 4A/B; adenovirus (AdV); HBoV; coronavirus (CoV 229E); enterovirus (EV)], were performed by using a commercial system namely CLART®Pneumovir (Cl …

Prevention, diagnosis and management of community acquired respiratory virus infections including COVID-19 in patients with cancer: 2025 updated evidence-based guideline of the infectious diseases working party (AGIHO) of the German society for hematology and medical oncology (DGHO).

Community-acquired respiratory viruses (CARV), such as influenza-, parainfluenza- or respiratory syncytial virus, pose a significant threat to immunocompromised patients with cancer. Following the COVID-19 pandemic, SARS-CoV-2 has now joined the ranks of endemic respiratory viruses and continues to be a cause of significant morbidity and mortality in patients with cancer. Strategies to protect this vulnerable patient population both by prevention of infection and by early therapeutic intervention in case of infectious disease are therefore of utmost importance. This guideline provides updated

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… al (2013) Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus. … Marinari LA Lower respiratory tract infection with human metapneumovirus: chest CT imaging features and comparison with other viruses Eur J Radiol 2020 128 108988 10.1016/j.ejrad.2020.108988 32388320 Marinari LA et al (2020) Lower respiratory tract infection with human metapneumovirus: chest CT imaging …

Risks and burden of viral respiratory tract infections in patients with multiple myeloma in the era of immunomodulatory drugs and bortezomib: experience at an Australian Cancer Hospital.

IntroductionInfections are a leading cause of morbidity and mortality in patients with multiple myeloma. The epidemiology, risk factors and outcomes of viral respiratory tract infections (vRTI) are not well described in patients with multiple myeloma managed with novel agents, the current standard of care.MethodsPatients with myeloma from 2009 to 2012 who tested positive on respiratory virus multiplex polymerase chain reaction had clinical, radiological and microbiological records reviewed. The Fourth European Conference on Infections in Leukaemia (ECIL-4) definitions of RTI were applied. Univ

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… Human metapneumovirus (HMPV) was included for detection in the panel in 2012. Statistical analysis Characteristics of patients with vRTI were summarised as proportional outcomes. Categorical variables were compared using the Fisher’s exact test. … Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus. Clin Infect Dis. 2013;56:258–266. doi: 10.1093/cid/cis844. 7. …

Respiratory Viral Infections in Recipients of Cellular Therapies: A Review of Incidence, Outcomes, Treatment, and Prevention.

Respiratory viral infections (RVIs) are of major clinical importance in immunocompromised patients and represent a substantial cause of morbidity and mortality in patients with hematologic malignancies and those who have undergone hematopoietic cell transplantation. Similarly, patients receiving immunotherapy with CD19-targeted chimeric antigen receptor-modified T cells, natural killer cells, and genetically modified T-cell receptors are susceptible to RVIs and progression to lower respiratory tract infections. In adoptive cellular therapy recipients, this enhanced susceptibility to RVIs resul

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… Infections Abbreviations: ALL, acute lymphoblastic leukemia; B-ALL, B-cell acute lymphoblastic leukemia; BCL, B-cell lymphoma; BCMA, B-cell maturation antigen; CAR-T, chimeric antigen receptor–modified T-cell therapy; CLL, chronic lymphocytic leukemia; DLBCL, diffuse large B-cell lymphoma; hMPV, human metapneumovirus … For patients with presumptive or confirmed RVI before CAR T-cell therapy, lymphodepleting chemotherapy should be delayed for 2 weeks or until symptoms resolve [ 23 ], especially for RSV, hPIV types 1–4, influenza virus A or B, and metapneumovirus [ 32 ]. …

Acute Pneumonia

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… CHILDREN | ADULTS Common | Common Respiratory syncytial virus Parainfluenza virus types 1, 2, 3 Influenza A virus Influenza B virus Rhinovirus Bocavirus Human metapneumovirus | Influenza A virus Influenza B virus Respiratory syncytial virus Human metapneumovirus Adenovirus types 4 and 7 (in military … Most cases of human metapneumovirus infection involve upper respiratory tract infections in children; pneumonia in adults has been described. 182 , 183 Multilobar infiltrates have been noted in 50% of cases, and pleural effusions are not uncommon. …

Epidemiological and etiological characteristics of 1266 patients with severe acute respiratory infection in central China, 2018-2020: a retrospective survey.

BACKGROUND: Severe acute respiratory infection (SARI), a significant global health concern, imposes a substantial disease burden. In China, … iratory syncytial virus, parainfluenza virus, adenovirus, human bocavirus, human coronavirus, human metapneumovirus, and rhinovirus. Bacterial cultures of respiratory specimens were performed with a particular focus on pathogenic microorganisms, including S. pneumoniae, S. aureus, K. pneumoniae, P. aeruginosa, Strep A, H. influenzae, A. baumannii, and E. coli. In …

Pulmonary and Hepatic Complications of Hematopoietic Cell Transplantation

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… The clinical impact of recently described viruses including human metapneumovirus and non-SARS human coronaviruses is not yet clear. Human metapneumovirus (hMPV) is a paramyxovirus recently recognized as the first human pathogen within the genus Metapneumovirus (van den Hoogen et al. 2004 ). … Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients. Ann Intern Med. 2006;144(5):344–349. doi: 10.7326/0003-4819-144-5-200603070-00010. Fattal-German M, Le Roy Ladurie F, Cerrina J, Lecerf F, Berrih-Aknin S. …

Consistent FFP2-masking as part of reducing viral respiratory infections on medical wards for allogeneic hematopoietic stem cell transplantation.

Patients undergoing allogenic hematopoietic stem cell transplantation (allo-HSCT) are highly susceptible to infections. The consequent use of masks on wards for allo-HSCT has been controversial in the past decades and was not common before the COVID-19 pandemic. We retrospectively compared incidence and outcomes of viral respiratory infections during allo-HSCT on our specialized ward between 01/2018 and 09/2020 to the era of FFP2 masking between 10/2020 and 10/2022 covering similar seasons of the year. Each group consisted of 150 matched patients. The usage of FFP2 masks reduced the incidence

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… The common pathogens for RVIs include the influenza virus, the parainfluenza virus (PIV), the respiratory syncytial virus (RSV), the human metapneumovirus (HMPV), the human coronavirus (HCoV) and the human rhinovirus (HRV). … Proven pathogens in the era before obligatory masking were 19 cases of rhinovirus, 6 of parainfluenza, 4 of coronavirus (not covid-19), 2 of metapneumovirus and 1 bocavirus with one patient having 2 RVIs during his stay. After masking was implemented, just 3 cases of rhinovirus were diagnosed. …

Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea.

Hematopoietic stem cell transplantation (HSCT) is a treatment for hematologic malignancies, immune deficiencies, or genetic diseases, ect. Recently, the number of HSCTs performed in Korea has increased and the outcomes have improved. However, infectious complications account for most of the morbidity and mortality after HSCT. Post-HSCT infectious complications are usually classified according to the time after HSCT: pre-engraftment, immediate post-engraftment, and late post-engraftment period. In addition, the types and risk factors of infectious complications differ according to the stem cell

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… In addition, human metapneumovirus, adenovirus, coronavirus, and bocavirus can cause URTIs and LRTIs in HSCT patients [ 129 , 137 ]. … The risk factors for progression to LRTI have been discussed for PIV, human metapneumovirus, and rhinovirus URTIs, but treatment is not recommended because of a lack of evidence [ 129 , 137 , 140 ]. …