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Drugs for treating giardiasis.

BACKGROUND: Giardiasis infection may be asymptomatic, or can cause diarrhoea (sometimes severe), weight loss, malabsorption, and, in childre … rasitological outcomes rather than clinical improvement.Ten trials, from India, Mexico, Peru, Iran, Cuba, and Turkey, compared albendazole (400 mg once daily for five to 10 days) with metronidazole (250 mg to 500 mg three times daily for five to 10 days). This once-daily regimen of albendazole is probably equivalent to metronidazole at achieving parasi …

Herpesviruses excretion in saliva of pediatric transplant recipients.

BACKGROUND: Saliva samples could be used for follow-up of herpesviruses infection in pediatric transplant recipients. OBJECTIVE: With the aim of determining the frequency of herpesviral infections in saliva samples after transplantation, and the association with viremia and complications, a pilot longitudinal follow-up of pediatric Cuban transplanted recipients (kidney and liver) was performed. METHODS: Quantitative real-time polymerase chain reaction of cytomegalovirus (CMV), Epstein-Barr virus, herpes simplex virus, human herpesevirus-6 (HHV6), varicella zoster virus, and human herpesvirus…

[Phenotypic and molecular identification of extended-spectrum beta-lactamase (ESBL) TEM and SHV produced by clinical isolates Escherichia coli and Klebsiella spp. in hospitals].

Nosocomial infections caused by gram-negative bacilli which produce extended spectrum beta-lactamase (ESBL) are associated with the increase of morbidity and mortality in hospitals. The objective of this study was to evaluate the frequency of ESBL, specifically the TEM and SHV type, produced by Escherichia coli and Klebsiella spp. strains, and also to determine the antimicrobial susceptibility of these isolates in comparison with other antibiotic families. A total of 326 strains were collected between 2002-2004 from hospitals in Havana City. The susceptibility tests were carried out according

First Report of Ceratocystis fimbriata-Caused Wilt of Eriobotrya japonica in China.

The loquat (Eriobotrya japonica (Thunb.) Lindl.), an important perennial evergreen fruit crop that originated in China and is also cultivate … he xylem of the trunk. A fungus was consistently isolated from the leaf when diseased leaves were incubated between two slices of fresh carrot root. Spore masses were picked from the apices of perithecia and transferred to malt extract agar medium (MEA) and incubated at 25°C. After perithecium formation, observed perithecia were black, globose (176.0 t …

Cancer vaccines: an update with special focus on ganglioside antigens.

Vaccine development is one of the most promising and exciting fields in cancer research; numerous approaches are being studied to developed … taken part in a project carried out by the <Centro de Inmunologia Molecular> (CIM) from La Havana, Cuba, to developed new strategies for specific active immunotherapy. The project included two ganglioside based vaccines and one anti-idiotypic vaccine. We focused on two antigens: first GM3, an ubiquitous antigen which is over-expressed in several epith …

[Prevalence of potentially pathogenic bacteria in nasopharynx of healthy children attending a day care center in Havana City].

During the first six-month period of 2001, a descriptive cross-sectional study of carriage in healthy children attending a day-care center in Havana City was performed. The objective was to find out the prevalence of potentially pathogenic bacteria and its association with possible risk factors. The design took into account the international and domestic regulatory bioethical requirements. Swabs of posterior nasopharynx of 160 children were directly cultured in brain heart agar plus sheep blood and in brain heart agar plus NAD, hemine and bacitracin and incubated for 18-24 h. Resulting isolate…

Highlights from the first ecancer-Liga Colombiana contra el Cancer conference, 17-18 November 2016, Bogota, Colombia.

The first oncology conference organised by ecancer and the Liga Colombiana contra el Cancer took place on 17-18 November 2016 in Bogota. It was a highly successful event owing to the number of participants, the quality of the speakers, and the academic programme. Around 48 professors from 8 different countries came and shared their knowledge and experience of cancer management. They also talked about the most recent developments noted or achieved in this area. The keynote speech from Dr Nubia Muñoz was of great interest which was related to the safety of a HPV vaccine and the implications of a

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… They were radiotherapists, clinical oncologists, oncologist nurses, gynaecologists, haematologists, urologists, palliative care professionals, and medical students who welcomed the high quality guest speakers from Spain, France, USA, Chile, Mexico, Peru, Argentina, Cuba and Colombia. … Dr Danay Saavedra, immunologist from the Centro de Investigaciones Moleculares in Cuba, spoke to us about the therapeutic vaccine CIMAVax-EGF and the results taken over several years in non-small cell lung cancer patients. …

Development and validation of a composite digital balance score for spinocerebellar ataxia: a prospective study.

BACKGROUND: Clinical trials in spinocerebellar ataxia are currently limited by the large sample sizes required by available clinical endpoin … xia types 1, 2, 3, or 6, recruited during clinical visits at five sites (four in the USA and one in Cuba) between June 23, 2017, and Aug 21, 2024. Participants were included if they had genetic confirmation of spinocerebellar ataxia, and were able to provide consent, walk 10 m independently without an assistive device, and stand unassisted for 30 s. A …

Alternative versus standard packages of antenatal care for low-risk pregnancy.

BACKGROUND: The number of visits for antenatal (prenatal) care developed without evidence of how many visits are necessary. The content of e … ew came from the three large, well-designed cluster-randomised trials that took place in Argentina, Cuba, Saudi Arabia, Thailand and Zimbabwe. All results have been adjusted for the cluster design effect. All of the trials were at some risk of bias as blinding of women and staff was not feasible with this type of intervention. For primary outcomes, evi …