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[Characteristics of surgical treatment of pathologic conditions of the cervical stump].

The paper gives the results of surgical management in 65 patients with cervical stump diseases. According to the pattern of the disease, 4 groups of patients were identified: 1) those with inflammatory diseases, 2) those with endometriosis, 3) those with myoma, and 4) those with prolapse of the cervical stump. Low-quality and inadequate suture material was found to be a cause of inflammatory diseases of the cervical stump. It is concluded that it is not expedient to use capron, lavsan, and silk to suture the cervical stump during supravaginal amputation of the uterus. Catgut, vicryl, debone we…

Определение стабильных и высокоурожайных генотипов кукурузы с использованием показателей стабильности на основе БЛУП и многопробегового отбора в различных средах.

Мейз (Zea Mays L.) one Наиболее важные зерновые культуры во всем мире служат основным источником продовольствия, корма и промышленного сырья; однако выявление высокоурожайных и стабильных генотипов кукурузы в различных средах является одной из ключевых целей программ улучшения кукурузы. Всего 60 Проведена оценка генотипов кукурузы four среды [лето] 2023 (E1), зима 2023 (E2), лето 2024 (Е3) и зима 2024 (Е4)] в конструкции альфа-латице с two тиражирование, включая six неполные блоки с 10 данные в блоке. Впоследствии 15 Для выявления более совершенных и стабильных генотипов кукурузы в различных с

Совпадение в аннотации оригинала
Maize (Zea mays L.) is one of the most important cereal crops worldwide and serves as a major source of food, feed, and industrial raw mater … 92.40%), biological yield (97.10%), cob yield (92.60%), and plant height (99.20%), whereas anthesis silking interval showed low heritability (12.70%), indicating strong environmental influence. Grain yield exhibited strong positive genotypic correlations with cob yield, biological yield, plant height, kernels per ear, ear length, seed index, and ear di …

[Role of attached gingiva in the extension of gingival inflammation. An experimental study in monkeys].

The purpose of this study was to evaluate the inflammatory response in dento-gingival units with or without attached gingiva in monkeys. Two … inical attachment level were recorded and oral photographs were taken. Following these examinations silk ligatures were placed around the neck of the teeth to induce gingival inflammation in both the experimental and control groups. A soft diet which allowed plaque accumulation on the teeth was given during the experimental periods. The clinical examin …

Protocol for extrusion 3D bioprinting of human-scale cardiac patches using cardiac spheroid-laden bioinks.

Extrusion-based bioprinting is a promising approach for developing novel clinical therapies for heart failure patients. Here, we present a protocol for bioprinting personalized human-scale cardiac patches incorporating human cardiac spheroids in a 1% silk fibroin/4% alginate/8% gelatin hydrogel. We describe steps for extrusion 3D bioprinting using a temperature-controlled hydrogel bioink. We also detail adjusting print parameters for optimal results. Although prepared for a specific experimental setup, the techniques described can be applied to other temperature-controlled biomaterials or extr…

Limb shaking transient ischemic attack secondary to innominate artery stenosis.

Limb shaking transient ischemic attack is a rare disease manifestation typically caused by carotid stenosis but rarely caused by flow-limiti … rization with innominate artery stenting. Continuous retrograde aspiration with the Enroute system (Silk Road Medical) and carotid clamping were used for embolic protection.

Intracardiac Thrombi in Morbus Adamantiades-Behçet in Two Swedish Patients.

Morbus Adamantiades-Behçet (MAB) is an inflammatory disease typically manifesting with oral and genital aphthosis, erythema nodosum, and vasculopathy, and in only around 2%, cardiac involvement. Its prevalence is usually higher along the historic Silk Road, but rarer in Scandinavia where 0.64-4.9 in 100,000 people are affected. We herein present two Swedish patients with cardiac manifestations of Morbus Adamantiades-Behçet. Along with the intracardial thrombi, which both patients presented with, one patient also had cerebrovascular insults leading to visual field deficits as well as involvemen…

[Transcesarean ileal resection of double Meckel diverticulum].

We report the case of Ileal resection, in a woman aged 27 during Kerr Caesarean section, we observe two ileum bag located at 20 and 40 cm, from the ileocecal valve, the farthest and largest containing air with breaking risk. Ileal surgical excision was performed with entero-entero anastomosis with silk sutures number 00. Postoperative treatment: antibiotics for 7 days: amikacin 500 mg intravenously every 12 hours and ceftriaxone 1 g every 8 hours. Fasting for 5 days diet progression to oral tolerance and normal bowel movements. Discharged from hospital on the seventh day after surgery in good …

MFG-E8 glycoprotein in inflammatory tissue regeneration: molecular mechanisms, therapeutic potential and advanced polymeric biomaterial delivery strategies.

Milk fat globule epidermal growth factor 8 (MFG-E8) is a multifunctional glycoprotein that coordinates efferocytosis, inflammatory resolutio … rs, offer protection, sustained release, and targeted delivery. This review systematically compares silk fibroin, PLGA, collagen, and chitosan-based platforms for MFG-E8 delivery, critically discusses translational bottlenecks (protein-polymer compatibility, manufacturing reproducibility, and safety), and proposes AI-driven co-engineering, closed-loop …

Surgical treatment of concomitant congenital left gastro-azygos and extrahepatic umbilico-caval portosystemic shunts in a dog.

A 6-month-old intact male English bull terrier dog was presented with chronic intermittent gastrointestinal signs followed by acute central nervous deficits. The dog was diagnosed, using computed tomography angiography, with concomitant congenital extrahepatic left gastro-azygos portosystemic shunt and extrahepatic umbilico-caval shunt; these were surgically attenuated with a complete silk suture ligation and placement of an Ameroid constrictor, respectively. The surgical outcome was successful and long-term follow-up was excellent. Key clinical message: This case report describes the features…

Anastomotic stricture following repair of esophageal atresia.

Anastomotic strictures developed in 74 (37.2%) of 199 patients undergoing primary or delayed primary repair of esophageal atresia with or without tracheoesophageal fistula. Significant predisposing factors included the use of braided silk sutures (relative risk 1.72 and 1.49, compared with polyglycolic acid and polypropylene sutures), the presence of gastroesophageal reflux and leakage of the anastomosis (relative risk 2.29 and 2.04, respectively). Tracheomalacia, personnel factors, and recurrent fistula did not affect the rate of stricture formation. Seventy-one patients responded to dilatati…

Widespread venous thrombosis: Unveiling a complex case of Behçet's disease with a literature perspective.

BACKGROUND: Behçet's disease, first described by Hippocrates and later recognized in modern medicine after Hulusi Behçet's description in 1937, is a complex vasculitis often referred to as the "Silk Road" disease. It is more prevalent in the Middle East and Mediterranean regions, primarily affecting males aged 25-35. CASE PRESENTATION: This study first describes the clinical presentation, timeline, diagnostic evaluation, and therapeutic interventions of one patient. Subsequently, the challenges in diagnosing the disease and selecting treatment strategies are discussed in detail. Finally, the …

Flow diversion of a dissecting PICA aneurysm.

A 47-year-old female with a history of a ruptured left posterior inferior cerebellar artery (PICA) aneurysm, status post coil embolization and retreatment for recurrence, presented with evidence of a recurrent dissecting PICA aneurysm. Given that these aneurysms are considered high risk and have a greater propensity for rupture than anterior circulation aneurysms, retreatment was recommended. With the patient's strong preference for endovascular therapy, flow diversion with a Silk Vista Baby was performed. Given the low-profile design of the device, a radial artery approach and coaxial techniq…

Surgical management of parotid salivary duct rupture secondary to non-iatrogenic trauma in a dog.

A 3-year-old French bulldog presented for evaluation of recurrent swelling and a fistula on the right cheek after a dog fight. A large volume of serous fluids was identified on the wound immediately after atropine drops. A diagnosis of parotid salivary duct rupture secondary to trauma was made. On surgical exploration, the thickened proximal segment of the severed duct was identified and circumferentially double ligated with 3-0 silk. No evidence of swelling and normal appearance of the parotid salivary gland were identified 4 months postoperative recheck. No further problems were noted 10 mon…

Spider-venom peptides as therapeutics.

Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid subjugation of prey. Most spider venoms are dominated by disulfide-rich peptides that typically have high affinity and specificity for particular subtypes of ion channels and receptors. Spider venoms are conservatively predicted to contain more than 10 million bioactive peptides, making them a valuable resource for drug discovery. Here we review …

Local opioids in a model of periodontal disease in rats.

There is growing evidence for the participation of opioid receptors in the development of inflammation. The present study was designed to clarify the role played by opioid receptors in periodontal disease. Periodontal disease was induced by placing a sterile silk ligature around the cervix of the second maxillary tooth on day 0. Morphine was administered either systemically or locally before and after the onset of periodontal disease. The results showed that in both patterns, morphine treatment reduced fiber attachment and alveolar bone loss, without affecting the increased leukocyte count in …

Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.

We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome. Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots. A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found…

Surgical gloves.

Surgeons and obstetricians, over the centuries, were only too aware that accidental open injuries during their work, especially in a septic … med Walbaum protected his hands by covering them with sheep's caecum. Others used gloves of cotton, silk and leather. After Charles Goodyear developed the vulcanisation process to stabilise rubber in 1844, this became the material of choice for these rather crude protective gloves.

Surgical treatment of giant hemangiomas of the head and neck.

This article is a review of 22 cases of giant hemangiomas of the head and neck treated at the American University of Beirut Medical Center over a 20-year period 1964 to 1984. All these cases were treated by surgical excision. Two maneuvers designed to reduce blood loss during the operation are described: the placement of strangulating silk sutures around the periphery of the hemangioma, and temporary occlusion of the ipsilateral external carotid artery. These cases were studied as to age, sex, site, size of hemangioma, histopathologic characteristics, mode of treatment, and results. A review o…

Proteomic profiling reveals immunologic mediators of endotoxin-related lung function decline: a longitudinal prospective study in textile workers.

BACKGROUND: Endotoxin is a major pathogenic component of cotton dust in the textile industry. While airborne endotoxin is associated with lung function decline, the underlying molecular mechanisms remain unclear. Proteomic profiling could provide important insights into the pathways that drive the harmful respiratory effects of endotoxin. METHODS: We conducted serum proteomic profiling of 221 endotoxin-exposed cotton workers and 192 endotoxin-free silk workers from the longitudinal cohort of the Shanghai Textile Worker Study. Using blood samples collected in 2016, proteins were quantified by d…

Hagfish-inspired hydrogel for root caries: A multifunctional approach including immediate protection, antimicrobial phototherapy, and remineralization.

Root caries is the main cause of oral pain and tooth loss in the elderly. Protecting root lesions from environmental disturbances, resisting … a mechanical self-regulating multifunctional platform for root caries treatment. The fluid system (silk fibroin-tannic acid-black phosphorene-urea, ST-BP-U), in which urea disrupts the hydrogen bonds between silk fibroin and tannic acid, can easily spread on the irregular root surface and permeate into dentinal tubules. Upon contact with the surroundi …