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How Would You Manage This Patient With Osteoporosis?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.

Osteoporosis is a skeletal disorder characterized by reduced bone strength that increases the risk for fracture. Approximately 10 million men and women in the United States have osteoporosis, and more than 2 million osteoporosis-related fractures occur annually. In 2016, the American Association of Clinical Endocrinologists issued the "Clinical Practice Guideline for the Diagnosis and Treatment of Postmenopausal Osteoporosis," and in 2017, the American College of Physicians issued the guideline "Treatment of Low Bone Density or Osteoporosis to Prevent Fracture in Men and Women." Both guideline

Incidence of rotavirus gastroenteritis hospitalizations and genotypes, before and five years after introducing universal immunization in Israel.

BACKGROUND: Uncertainty exists about the sustainability of the reduction in rotavirus gastroenteritis (RVGE) following the introduction of rotavirus vaccines into national immunization programs, and on its potential impact on circulating genotypes. RotaTeq was introduced into the Israeli national immunization program in December 2010, and vaccination coverage is around 80%. AIMS: To examine the change in incidence of RVGE hospitalization and rotavirus genotypes, during the five years after introduction of RotaTeq into the Israeli national immunization program. METHODS: Data were obtained pro…

Current data on acute haematogenous osteomyelitis in children in Southern Israel: epidemiology, microbiology, clinics and therapeutic consequences.

BACKGROUND: Acute haematogenous osteomyelities (AHO) is the most common form of osteomyelitis, occurring when bone is infected secondary to transient bacteremia. The prevalence, aetiology and outcome of AHO may vary from region to region and period to period. The study objectives were to define the epidemiology, clinical, laboratory and imaging characteristics and treatment consequences of AHO in children in southern Israel. METHODS: This was a retrospective cohort study, enrolling all children <16 years of age hospitalized with AHO. Epidemiologic, clinical, laboratory and imaging data were r…

Prolonged Exposure for Treating PTSD Among Female Methadone Patients Who Were Survivors of Sexual Abuse in Israel.

The aims of this pilot study were: (a) to test the feasibility of prolonged exposure (PE) therapy conducted by a social worker staff on female patients in methadone program clinics who were survivors of child sexual abuse or rape and (b) to examine preliminary outcomes of PE on posttraumatic stress disorder (PTSD), depression, and illicit drug use at pre- and posttreatment, and up to 12-month follow-ups. Twelve female methadone patients who were survivors of child sexual abuse or rape diagnosed with PTSD were enrolled in 13-19 weekly individual PE sessions. Assessments were conducted at pre-,

[Alertness is its own reward: adult type Hirschprung's disease--clinical description of first two cases in Israel].

Hirschprung disease is well known. The basic pathogenesis is lack of parasympathetic ganglia in the large bowel wall, part of it, or all of it. The absence of these ganglia paralyzes the involved segment leading to obstruction. Almost all babies are diagnosed and operated upon in their first year. Few rare cases manage to grow and reach maturity without diagnosis. These patients are characterized by severe constipation and grade III-IV hemorrhoids. This is adult type Hirschprung's disease. Two first cases in Israel were diagnosed, patients were operated upon, and recovered. Adult type Hirschpr…

Филогенетические связи вирусов Западного Нила, изолированных от птиц и лошадей в Израиле с 1997 по 2001 год.

В ноябре 1997 года вспышка нейропаралитической болезни, вызванной вирусом Западного Нила (WN), была диагностирована у молодых гусиных стадов. В конце лета и осенью 1998, 1999, 2000 и 2001 годов также пострадали домашние гуси. В 1998-2001 годах вирусы WN были также изолированы от мигрирующих и диких птиц и лошадей. Последовательность 1278 bp гена конверта 24 израильского вируса WN была сопоставлена с последовательности из семи изолированных от Африки, Европы и Нью-Йорка. В результате этого израильские изолированные группы можно было бы затем сгруппировать в две группы. Было установлено, что 15

Совпадение в аннотации оригинала
In November 1997, an outbreak of a neuroparalytic disease caused by West Nile (WN) virus was diagnosed in young goose flocks. Domestic geese were similarly affected in the late summer and fall of 1998, 1999, 2000 and 2001. WN viruses were also isolated from migratory and wild birds and horses in 1998-2001. A 1278 bp sequence of the envelope gene of 24 Israel…

Two-year follow up study of stress-related disorders among immigrants to Israel from the Chernobyl area.

We report on findings from a 2-year follow-up study of immigrants originating from exposed areas around the site of the 1986 Chernobyl accid … tudy shows that levels of psychological distress are waning as the new immigrants are absorbed into Israeli society. However, there still remains some independent effect on health associated with the experience of the Chernobyl accident.

High prevalence of vitamin D deficiency among Ethiopian women immigrants to Israel: exacerbation during pregnancy and lactation.

A population of 125 adult Ethiopian women immigrants to Israel was screened for serum levels of calcium, phosphorus, and alkaline phosphatase. Five women (prevalence of 4%) had hypocalcemia and in one of them osteomalacia was found. In the other 120 subjects normal values were recorded. All five patients had low serum levels of 25 hydroxy (OH) vitamin D3 and high parathyroid hormone (PTH) levels. In four of the five patients, clinical and biochemical manifestations of vitamin D deficiency were detected during pregnancy or lactation. Treatment with vitamin D2 for 4-13 months resulted in clinica…

Molecular epidemiology of type 1 polioviruses isolated in Israel and defined by restriction fragment length polymorphism assay.

The genomic variability of 27 type 1 polioviruses (PV-1) isolated in Israel during 1980-1991 was examined by restriction fragment length polymorphism (RFLP) analysis of a reverse-transcribed genomic fragment amplified by polymerase chain reaction. By using the restriction enzymes HaeIII, DdeI, and HpaII, strain-specific restriction profiles were generated for the PV-1/Mahoney and PV-1/Sabin strains and 27 wild-type isolates. The profile observed for PV-1 isolated during an outbreak in 1988 was also observed for PV-1 isolated from different places in Israel in 1982 and 1983, 1987, and 1991. Thi…

Atherosclerosis and von Willebrand factor. I. Prevalence of severe von Willebrand's disease in western Europe and Israel.

The prevalence of von Willebrand's disease (VWD) in Western European countries and Israel was assessed. Possible patients were identified initially by questionnaire and those with plasma levels of von Willebrand factor antigen ( WFAg ; factor VIII related antigen) less than 1 u/dl (less than 1%) were confirmed by immunoradiometric assay performed at four reference centres. The prevalences of severe VWD in Scandinavian countries were similar to each other and about 10 times greater than those in other Western European countries. The prevalence in Israel was intermediate. The Registry will form …

Bilharziasis survey in south-western Asia; covering Iraq, Israel, Jordan, Lebanon, Sa'udi Arabia, and Syria: 1950-51.

This paper describes a limited survey of bilharziasis and its vectors carried out during 1950 and 1951 in some countries of south-western As … the irrigated areas of Iraq and is also present, in comparatively smaller foci, in northern Syria, Israel, and Sa'udi Arabia. In the opinion of the senior author (M. A. A.), the envisaged extension of irrigation is likely to create a serious health problem in Mesopotamia and to introduce the disease into the Jordan region unless the spread of the mollus …

Western Models of PTSD Rehabilitation Among Military Veterans: A Narrative Comparative Review and Policy Implications for Israel.

Background: Post-Traumatic Stress Disorder (PTSD) is among the most prevalent and disabling mental health conditions affecting military vete … al models of PTSD rehabilitation among military veterans and to derive policy-relevant insights for Israel. Methods: We conducted a narrative comparative review of peer-reviewed literature and national policy documents published between 2014 and 2023, examining military and veteran PTSD rehabilitation frameworks in six Western countries: the United State …

Psychological outcomes and resilience among evacuees and non-evacuees following the October 7 Hamas attack in Israel.

The October 7th, 2023 Hamas attack on Israel's southern territory marked one of the most devastating events in the nation's history, and the ensuing war with Hamas in the south and Hezbollah in the north resulted in the internal displacement of more than a quarter million Israelis. In the current study we examined the impact of these traumatic events on 636 Israeli Jewish evacuees (n = 300) and non-evacuees (n = 336), focusing on the differential effects of personal resilience, community resilience, and trust in formal authorities on post-traumatic stress symptoms (PTSS) and life functioning. …

What Non-Professional Community Members From Minority Groups in Israel Think About Alzheimer's Disease: A Comparative Perspective.

Alzheimer's disease (AD) is the most common cause of dementia worldwide, yet awareness, diagnosis-seeking, and caregiving practices are strongly shaped by cultural and social contexts. Minority groups often face compounded barriers due to stigma, limited knowledge, and systemic inequalities. In Israel, a multicultural society, little is known about how non-professional community members from different minority groups perceive AD, seek diagnosis, and conceptualize appropriate care. We conducted a qualitative comparative study using six focus groups with 43 non-professional community members fro…

Lived Experiences of Adoptive Parents Raising Children with Fetal Alcohol Spectrum Disorders in Israel: A Qualitative Study.

Background: Fetal alcohol spectrum disorders (FASDs) are lifelong neurodevelopmental conditions resulting from prenatal alcohol exposure. Despite high FASD rates in high-risk adoptive populations, little is known about the experiences of adoptive parents in Israel, where underdiagnosis and limited professional awareness persist. Drawing on ecological and family systems theory, this study explored the daily challenges, coping strategies, and service-related barriers encountered by adoptive parents raising children with FASD. Methods: Using a qualitative, exploratory design, semi-structured inte…

Parental competence during war: Aspects of resilience and moral injury among body handlers and civilians in Israel.

OBJECTIVE: This study examined how traumatic stress symptoms (TSS) influence parental competence (PC) among Israeli civilian parents and reservist body handlers during the Gaza war, and explored two psychological mechanisms, moral injury and psychospiritual resilience, that may exacerbate or buffer these effects. METHOD: Three hundred seventeen parents (137 body handlers, 180 civilians) completed validated measures of TSS, moral injury, psychospiritual resilience, and PC. RESULTS: Structural equation modeling revealed that TSS was strongly associated with reduced PC in both groups. However, …

Alternative Childhood Vaccination Schedules in Israel: A Mixed-Methods Study on Prevalence, Patterns, and Public Health Implications.

Background/Objectives: Vaccination programs are highly effective public health interventions, yet parental hesitancy toward combination vacc … evalence patterns and parental motivations for requesting such alternative vaccination schedules in Israel, where national guidelines recommend specific combination vaccines, including measles-mumps-rubella-varicella (MMRV) and the pentavalent diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type b (DTaP+IPV+Hib) vaccines, but inform …

Multi-parametric analysis of thunderstorm ground enhancements (TGE) and associated gamma-ray emissions on Mount Hermon, Israel.

Thunderstorm Ground Enhancements (TGEs), sometimes referred to as gamma-ray glows, are transient increases in surface-level gamma-ray flux driven by thunderstorm electric fields. This study investigates two TGE events observed on January 4-6 and January 14, 2018, at the Emilio Segre Cosmic-Ray Observatory on Mount Hermon in northern Israel. Both cases were under rain-free conditions, thus excluding radon washout effects. Gamma-ray counts, vertical electric field strength, neutron flux, and lightning data were continuously monitored, enabling a detailed analysis of possible TGE mechanisms. Both…

Molecular characterization of two Myxidium species (Cnidaria: Bivalvulida: Myxidiidae) infecting barbs in the Sea of Galilee, Israel.

Myxozoans are parasitic cnidarians that can cause severe damage to fish, resulting in economic losses to aquaculture and fisheries. In Israel, only a few taxonomic studies have been conducted on Myxozoa infecting freshwater fish and none on barb parasites. Here, we describe two new myxozoan species - Myxidium grauri n. sp. and Myxidium sharmai n. sp. - from the gallbladder of the barbs Carasobarbus canis and Luciobarbus longiceps, respectively, from the Sea of Galilee (Lake Kinneret). The prevalence of infection was 42.2% (19/45) for M. grauri n. sp. and 25% (5/20) for M. sharmai n. sp. We obt…