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Surgical interventions for primary congenital glaucoma.

BACKGROUND: Primary congenital glaucoma (PCG) manifests within the first few years of a child's life and is not associated with any other sy … still remains uncertain. Adverse events, such as choroidal detachment, shallow anterior chamber and hyphema, were reported from four trials. None of the trials reported quality of life or economic data.These trials were neither designed nor reported well overall. Two trials were quasi-randomized trials and judged to have high risk of selection bias; four …

Pattern of ocular injuries in Bangladesh and its surgical management at hospital setting: A retrospective study.

OBJECTIVE: To determine the pattern of ocular injuries and their surgical management.. METHODS: The retrospective study was conducted at the Chittagong Eye Infirmary and Training Complex, Chittagong, Bangladesh, and comprised hospital data of patients with ocular injuries from October 1, 2016, to December 31, 2017. Information gathered related to type and cause of injuries, visual acuity, postoperative complications, follow-up visits, and outcome. SPSS version 22 was used for data analysis. RESULTS: Of the total injuries, 370 (91%) were classified open globe and 36 (9%) as close globe. In te

Persistent hyperplastic primary vitreous: diagnosis, treatment and results.

While the great majority of patients with persistent hyperplastic primary vitreous never obtain useful vision, it is encouraging that 18.07% … cause a secondary angle-closure glaucoma. A secondary glaucoma can also be produced from recurrent hyphema, which scars the outflow passageways in the angle. By removing the PHPV membrane and reducing the tractional forces applied to the ciliary body by the membrane, one can lessen the possibility of phthisis. Surgery reduces the centripetal, as well as …

Emergency Care

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Сердечно-сосудистые заболевания

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Build Your Own Eye: A Method for Teaching Ocular Anatomy and Pathophysiology.

AUDIENCE: Residents and medical students. INTRODUCTION: The eye is a critical, but often neglected, part of medical learning. This team-bas … vitis, episcleritis, globe rupture, iritis, uveitis, anterior uveitis, posterior uveitis, hypopyon, hyphema, acute angle closure glaucoma, congenital pupillary deformity, coloboma, globe rupture, nevus, essential iris atrophy, cataracts, presbyopia, myopia, hyperopia, traumatic iritis, iridocyclitis, ciliary body melanoma, vitreous degeneration, vitreous …

Manifestations of systemic disease in the retina and fundus of cats and dogs.

The fundus is unique in that it is the only part of the body that allows for a noninvasive and uninterrupted view of vasculature and nervous tissue. Utilization of this can be a powerful tool in uncovering salient incidental findings which point to underlying systemic diseases, and for monitoring response to therapy. Retinal venules and arterioles allow the clinician to assess changes in vascular color, diameter, outline, and tortuosity. The retina and optic nerve may exhibit changes associated with increased or decreased thickness, inflammatory infiltrates, hemorrhages, and detachments. While

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… The left eye was noticeably microphthalmic and had uveitis and hyphema. Both eyes had a cataract and the ocular fundus was not readily visible. A retinal detachment was seen ultrasonographically in the left eye offering an explanation for the source of blood. … (F) Hyphema and blood clots are formed in the anterior chamber. (G) Optic neuritis, subretinal and vitreal hemorrhage in the right eye of a dog affected by immune mediated thrombocytopenia. …

Сердечно-сосудистые заболевания

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Primary choroidal lymphoma with extrascleral extension and bone marrow involvement: a case report.

Primary extranodal marginal zone B-cell lymphoma (EMZL) of the choroid is a rare condition with a handful of cases reported in the literature. Here, we report a challenging case of primary EMZL of the choroid with extrascleral extension and bone marrow involvement. An 86-year-old male presented with 2 years of progressive vision loss in his left eye. Fundus examination revealed yellow-white subretinal infiltrates at the posterior pole. Ultrasonography detected diffuse choroidal thickening with retrobulbar hypoechoic mass. One year later, an inferior exudative retinal detachment developed. Ultr

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… Ophthalmoscopic fundus visualization was obscured by hyphema secondary to neovascular glaucoma. …

Cyclodestructive procedures for non-refractory glaucoma.

BACKGROUND: Glaucoma is a leading cause of blindness worldwide. It results in a progressive loss of peripheral vision and, in late stages, l … had transient conjunctival burns (percentages not reported). Severe iritis occurred in two eyes and hyphema occurred in three eyes. No instances of hypotony or phthisis bulbi were reported. The only adverse outcome that was reported by the treatment group was atonic pupil (RR 0.89 in the low-energy group, 95% CI 0.47 to 1.68; 92 participants; low-certaint …

Aductive laser iridoplasty and laser goniopuncture after non-perforating trabeculectomy.

INTRODUCTION: Successful non-perforating trabeculectomy (NPT) results in filtration of aqueous humor out of the anterior chamber and into a filtration bleb, without surgical excision of tissue from the anterior chamber angle, and without penetration into the anterior chamber. The complications of perforating trabeculectomy, due to early postoperative hypotony (shallow anterior chamber, hyphema, macular folds, suprachoroidal effusion, and ciliochoroidal hemorrhage) (3, 4, 5, 6, 7, 8, 9) are regarded by many surgeons as significant risks. Nonperforating surgery has been reported to reduce the in…

Cyclodestructive procedures for refractory glaucoma.

BACKGROUND: Cyclodestructive procedures are often used in patients with refractory glaucoma who have failed to achieve lower intraocular pre … 1.49, 95% CI 0.76 to 2.91; 50 participants; very low-certainty evidence). The presence of fibrin or hyphema were seen in five participants who received 8J and none who received 4J. There was a severe anterior chamber reaction in 11 of 26 (42%) participants who received 8J of energy and 2 of 21 (10%) participants who received 4J of energy. AUTHORS' CONCLU …

Feline Coronavirus Infection

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… Ocular signs include conjunctivitis, mucopurulent ocular discharge, thickening and hyperemia of the nictitans, uveitis with dyscoria or anisocoria, aqueous flare, keratic precipitates, hypopyon, hyphema, chorioretinitis, perivascular infiltrates, retinal detachment, or blindness ( Figure 20-5 ). …

State of the Art of Pharmacological Activators of p53 in Ocular Malignancies.

The pivotal role of p53 in the regulation of a vast array of cellular functions has been the subject of extensive research. The biological activity of p53 is not strictly limited to cell cycle arrest but also includes the regulation of homeostasis, DNA repair, apoptosis, and senescence. Thus, mutations in the p53 gene with loss of function represent one of the major mechanisms for cancer development. As expected, due to its key role, p53 is expressed throughout the human body including the eye. Specifically, altered p53 signaling pathways have been implicated in the development of conjunctival

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… As the tumor advances, affected individuals may develop hyphema, neovascular glaucoma, vitreous hemorrhage, or exudative retinal detachment. Extraocular tumor extension may be associated with significant proptosis and orbital inflammation [ 170 ]. …

Plasma Cell Disorders

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… Both bleeding and thrombotic problems can be observed. 81 Bleeding disorders including epistaxis, oral bleeding, melena, hyphema, and retinal hemorrhages have been reported in feline MRD. 1 , 29 , 48 , 56 Immunosuppression Numerous mechanisms for reduced cellular and humoral immunity have been described …

A review of feline infectious peritonitis virus infection.

Feline infectious peritonitis (FIP) is an infectious disease characterized by non-specific laboratory changes and clinical signs. Clinical symptoms include anorexia, jaundice, fever, and weight loss. Moreover, some lesions are found in the digestive and respiratory systems. FIP, whose virulence varies, cannot be distinguished using several diagnostic methods. Moreover, feline coronaviruses (FCoVs) can be classified into two serotypes based on differences in their amino acid sequences, spike (S) protein sequences, and antibody (Ab) neutralization. There are two pathotypes, namely those caused b

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… Exudation of either white blood cells (hypopyon) or red blood cells (hyphema) into the anterior chamber is indicative of uveitis and a significant breakdown of the blood-aqueous barrier. …

How does academia respond to the burden of infectious and parasitic disease?

BackgroundAcademic research is one of the main avenues through which humans can fight the threat of infectious diseases. However, there have been concerns regarding whether the academic system has provided sufficient efforts to fight infectious diseases we potentially face. Answering these questions could contribute to evidence-based recommendations for setting research priorities and third-mission policies.MethodsWith a focus on one of the most common categories of communicable diseases, infectious and parasitic diseases (IPDs), we searched Web of Science for articles and reviews relevant to

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… OR "Otitis externa" OR "Otitis media" OR "Presbycusis" OR "Tinnitus" OR "Vertigo" OR "Anisocoria" OR "Blepharitis" OR "eye cataract*" OR "Chalazion" OR "Conjunctivitis" OR "Corneal abrasion" OR "Corneal oedema" OR "Corneal ulcer" OR "Diplopia" OR "Dry eye syndrome" OR "Esotropia" OR "Glaucoma" OR "Hyphema …

Clinical outcomes of chemotherapy in cancer patients with different ethnicities.

BackgroundChoosing the most effective chemotherapeutic agent with safest side effect profile is a common challenge in cancer treatment. Although there are standardized chemotherapy protocols in place, protocol changes made after extensive clinical trials demonstrate significant improvement in the efficacy and tolerability of certain drugs. The pharmacokinetics, pharmacodynamics, and tolerance of anti-cancer medications are all highly individualized. A driving force behind these differences lies within a person's genetic makeup.Recent findingsPharmacogenomics, the study of how an individual's g

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… m 2 M: Liver CL: 201–810 mL/min/m 2 E: Urine (10%) | Crosslinks DNA, preventing replication and transcription | In a multi‐ethnic Asian community, individuals with primary open angle glaucoma and primary angle closure glaucoma who had phacotrabeculectomy with mitomycin‐C often experienced hypotony, hyphema …

Hematology and Immune-Related Disorders

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